• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Urm-0510
RPS6KB1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ribosomal protein S6 kinase
Gene Name: RPS6KB1
Ensembl Gene: ENSUMAG00000022704.1
Ensembl Protein: ENSUMAP00000031439.1
Organism: Ursus maritimus
Taxa ID: 29073
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRRRRRRDGF  YPVPDFQDRE  AEDMAGVFDI  DLDQPEDAGS  EDELEEGGQL  NESMDHGGVG  60
61    PYELGMEHCE  KFEISETSVN  RGPEKIRPEC  FELLRVLGKG  GYGKVFQVRK  VTGANTGKIF  120
121   AMKVLKKAMI  VRNAKDTAHT  KAERNILEEV  KHPFIVDLIY  AFQTGGKLYL  ILEYLSGGEL  180
181   FMQLEREGIF  MEDTACFYLA  EISMALGHLH  QKGIIYRDLK  PENIMLNHQG  HVKLTDFGLC  240
241   KESIHDGTVT  HTFCGTIEYM  APEILMRSGH  NRAVDWWSLG  ALMYDMLTGA  PPFTGENRKK  300
301   TIDKILKCKL  NLPPYLTQEA  RDLLKKLLKR  NAASRLGAGP  GDAGEVQAHP  FFRHINWEEL  360
361   LARKVEPPFK  PLLQSEEDVS  QFDSKFTRQT  PVDSPDDSTL  SESANQVFLG  FTYVAPSVLE  420
421   SVKEKFSFEP  KIRSPRRFIG  SPRTPVSPVK  FSPGDFWGRG  ASASTANPQT  PVEYPMETSG  480
481   VEQMDVTMSG  EASAPLPIRQ  PNSGPYKKQA  FPMISKRPEH  LRMNL  525
Nucleotide CDS Sequence (FASTA)
1     ATGAGGCGAC  GACGGAGGCG  GGACGGCTTT  TACCCAGTGC  CGGACTTCCA  AGACAGGGAA  60
61    GCTGAGGACA  TGGCAGGAGT  GTTTGACATA  GACCTGGACC  AGCCAGAGGA  CGCGGGCTCT  120
121   GAGGATGAGC  TGGAGGAGGG  GGGTCAGTTA  AATGAAAGCA  TGGACCATGG  GGGAGTTGGA  180
181   CCATATGAAC  TTGGCATGGA  ACATTGTGAG  AAATTTGAAA  TTTCGGAAAC  TAGTGTGAAC  240
241   AGAGGGCCAG  AAAAAATCAG  ACCAGAATGT  TTTGAGCTAC  TTCGGGTACT  TGGTAAAGGG  300
301   GGCTATGGAA  AGGTTTTTCA  AGTACGAAAA  GTAACAGGAG  CAAATACTGG  GAAAATATTT  360
361   GCCATGAAGG  TGCTTAAAAA  GGCAATGATA  GTAAGAAATG  CTAAAGATAC  AGCTCATACA  420
421   AAAGCAGAAC  GGAATATTCT  GGAGGAAGTA  AAGCATCCCT  TCATTGTGGA  TTTAATTTAT  480
481   GCCTTTCAGA  CCGGTGGAAA  ACTCTACCTC  ATCCTTGAGT  ATCTCAGCGG  AGGAGAATTA  540
541   TTTATGCAGT  TAGAAAGAGA  GGGAATATTT  ATGGAAGACA  CAGCCTGCTT  TTACTTGGCA  600
601   GAAATCTCCA  TGGCTTTGGG  GCATTTGCAT  CAAAAGGGGA  TCATCTACAG  AGACCTGAAG  660
661   CCGGAGAATA  TCATGCTTAA  TCACCAAGGT  CATGTGAAAC  TAACAGACTT  TGGACTATGC  720
721   AAAGAATCTA  TTCATGATGG  AACAGTCACA  CACACATTTT  GTGGAACAAT  AGAATACATG  780
781   GCCCCTGAAA  TCTTGATGAG  AAGTGGCCAC  AATCGTGCTG  TGGATTGGTG  GAGTTTGGGA  840
841   GCATTAATGT  ATGACATGCT  GACTGGAGCA  CCCCCGTTCA  CTGGGGAGAA  TAGAAAGAAA  900
901   ACAATTGACA  AAATCCTCAA  ATGTAAACTC  AATTTGCCTC  CCTACCTCAC  ACAAGAAGCC  960
961   AGAGATCTGC  TTAAAAAGCT  GCTGAAAAGA  AATGCTGCTT  CTCGGCTTGG  AGCTGGTCCT  1020
1021  GGGGATGCTG  GAGAAGTTCA  GGCTCATCCA  TTCTTCAGGC  ATATTAACTG  GGAAGAACTG  1080
1081  CTGGCTCGGA  AGGTGGAGCC  CCCCTTTAAA  CCTCTGTTGC  AATCTGAAGA  GGATGTGAGT  1140
1141  CAGTTTGATT  CAAAGTTTAC  ACGTCAGACA  CCTGTTGACA  GCCCAGATGA  CTCAACTCTC  1200
1201  AGTGAAAGTG  CCAACCAGGT  CTTTCTGGGT  TTTACATATG  TGGCTCCATC  TGTACTTGAA  1260
1261  AGTGTGAAAG  AAAAATTTTC  CTTTGAACCA  AAAATCCGAT  CACCTCGAAG  ATTTATTGGC  1320
1321  AGCCCACGAA  CACCTGTCAG  CCCGGTCAAA  TTTTCTCCTG  GGGATTTCTG  GGGAAGAGGT  1380
1381  GCTTCAGCCA  GCACGGCAAA  TCCTCAGACA  CCTGTGGAAT  ATCCCATGGA  AACAAGTGGA  1440
1441  GTAGAGCAGA  TGGATGTGAC  GATGAGTGGG  GAAGCTTCAG  CACCACTTCC  AATACGACAG  1500
1501  CCGAACTCCG  GGCCATACAA  AAAACAAGCT  TTTCCCATGA  TCTCCAAACG  ACCAGAGCAC  1560
1561  CTACGTATGA  ATCTATGA  1578

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aim-0691Ailuropoda melanoleuca100.00.01091
LLPS-Fec-0554Felis catus99.620.01088
LLPS-Caf-2859Canis familiaris99.620.01088
LLPS-Ova-0252Ovis aries99.580.0 991
LLPS-Anp-1262Anas platyrhynchos99.490.0 812
LLPS-Man-1381Macaca nemestrina99.430.01088
LLPS-Hos-0731Homo sapiens99.430.01088
LLPS-Pat-2026Pan troglodytes99.430.01088
LLPS-Cas-0494Carlito syrichta99.430.01088
LLPS-Mam-1690Macaca mulatta99.430.01088
LLPS-Caj-0286Callithrix jacchus99.430.01088
LLPS-Aon-1914Aotus nancymaae99.430.01088
LLPS-Chs-0817Chlorocebus sabaeus99.430.01088
LLPS-Maf-2257Macaca fascicularis99.430.01088
LLPS-Mup-0591Mustela putorius furo99.430.01087
LLPS-Myl-1220Myotis lucifugus99.430.01088
LLPS-Mal-0893Mandrillus leucophaeus99.430.01088
LLPS-Paa-2025Papio anubis99.430.01088
LLPS-Nol-0803Nomascus leucogenys99.420.01060
LLPS-Otg-0349Otolemur garnettii99.240.01086
LLPS-Loa-0123Loxodonta africana99.240.01085
LLPS-Ict-0250Ictidomys tridecemlineatus99.240.01085
LLPS-Eqc-1749Equus caballus99.240.01086
LLPS-Poa-1054Pongo abelii99.240.01087
LLPS-Cea-0019Cercocebus atys99.240.01085
LLPS-Bot-2699Bos taurus99.240.01086
LLPS-Sus-0893Sus scrofa99.050.01083
LLPS-Ran-0030Rattus norvegicus99.050.01083
LLPS-Tut-1095Tursiops truncatus99.050.01083
LLPS-Mum-1732Mus musculus98.860.01080
LLPS-Fud-0920Fukomys damarensis98.670.01078
LLPS-Ora-0278Ornithorhynchus anatinus98.330.0 979
LLPS-Meg-1314Meleagris gallopavo97.490.0 970
LLPS-Gaga-1174Gallus gallus97.410.01019
LLPS-Dio-2287Dipodomys ordii97.390.0 998
LLPS-Tag-1375Taeniopygia guttata96.810.01014
LLPS-Mod-2067Monodelphis domestica96.770.01042
LLPS-Pes-1910Pelodiscus sinensis96.220.01008
LLPS-Sah-1197Sarcophilus harrisii94.690.01020
LLPS-Anc-1275Anolis carolinensis94.250.0 990
LLPS-Fia-1713Ficedula albicollis94.180.0 975
LLPS-Cap-1558Cavia porcellus93.820.0 989
LLPS-Lac-0467Latimeria chalumnae93.070.0 832
LLPS-Pap-0237Pan paniscus91.890.0 971
LLPS-Xet-0418Xenopus tropicalis90.290.0 971
LLPS-Leo-0473Lepisosteus oculatus86.440.0 888
LLPS-Scf-3715Scleropages formosus86.390.0 824
LLPS-Rhb-2529Rhinopithecus bieti85.710.0 870
LLPS-Dar-1502Danio rerio84.780.0 879
LLPS-Asm-0886Astyanax mexicanus84.580.0 877
LLPS-Tar-0904Takifugu rubripes83.860.0 860
LLPS-Icp-0568Ictalurus punctatus83.790.0 864
LLPS-Gaa-0745Gasterosteus aculeatus83.40.0 856
LLPS-Orn-1506Oreochromis niloticus83.370.0 865
LLPS-Orl-3449Oryzias latipes83.170.0 865
LLPS-Scm-1710Scophthalmus maximus82.480.0 857
LLPS-Pof-0580Poecilia formosa81.980.0 836
LLPS-Xim-1284Xiphophorus maculatus80.630.0 836
LLPS-Ten-1095Tetraodon nigroviridis79.430.0 845
LLPS-Gog-3627Gorilla gorilla73.360.0 669
LLPS-Drm-0721Drosophila melanogaster72.830.0 565
LLPS-Cae-0265Caenorhabditis elegans68.381e-174 511
LLPS-Mea-3020Mesocricetus auratus66.060.0 647