• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Loa-0123
RPS6KB1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ribosomal protein S6 kinase
Gene Name: RPS6KB1
Ensembl Gene: ENSLAFG00000014259.3
Ensembl Protein: ENSLAFP00000011940.3
Organism: Loxodonta africana
Taxa ID: 9785
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRRRRRRDGF  YPAPDVRDRE  AEDMAGVFDI  DLDQPEDAGS  EDELEEGGQL  NESMDHGGVG  60
61    PYELGMEHCE  KFEISETSVN  RGPEKIRPEC  FELLRVLGKG  GYGKVFQVRK  VTGANTGKIF  120
121   AMKVLKKAMI  VRNAKDTAHT  KAERNILEEV  KHPFIVDLIY  AFQTGGKLYL  ILEYLSGGEL  180
181   FMQLEREGIF  MEDTACFYLA  EISMALGHLH  QKGIIYRDLK  PENIMLNHQG  HVKLTDFGLC  240
241   KESIHDGTVT  HTFCGTIEYM  APEILMRSGH  NRAVDWWSLG  ALMYDMLTGA  PPFTGENRKK  300
301   TIDKILKCKL  NLPPYLTQEA  RDLLKKLLKR  NAASRLGAGP  GDAGEVQAHP  FFRHINWEEL  360
361   LARKVEPPFK  PLLQSEEDVS  QFDSKFTRQT  PVDSPDDSTL  SESANQVFLG  FTYVAPSVLE  420
421   SVKEKFSFEP  KIRSPRRFIG  SPRTPVSPVK  FSPGDFWGRG  ASASTANPQT  PVEYPMETSG  480
481   IEQMDVTMSG  EASAPLPIRQ  PNSGPYKKQA  FPMISKRPEH  LRMNL  525
Nucleotide CDS Sequence (FASTA)
1     ATGAGGCGAC  GACGGAGGCG  GGACGGCTTT  TACCCAGCGC  CGGACGTCCG  AGACAGGGAA  60
61    GCTGAGGACA  TGGCAGGAGT  GTTTGACATA  GACCTGGACC  AGCCAGAGGA  CGCGGGCTCT  120
121   GAGGATGAGC  TGGAGGAGGG  GGGTCAGTTA  AATGAAAGCA  TGGACCACGG  GGGAGTTGGA  180
181   CCATATGAAC  TTGGCATGGA  ACATTGTGAA  AAATTTGAAA  TCTCAGAAAC  TAGTGTGAAC  240
241   AGAGGGCCAG  AAAAAATCAG  ACCAGAATGT  TTTGAACTAC  TTCGGGTACT  TGGTAAAGGG  300
301   GGCTATGGAA  AGGTTTTTCA  AGTACGAAAA  GTAACAGGAG  CAAATACTGG  AAAAATATTT  360
361   GCAATGAAGG  TGCTTAAAAA  GGCCATGATA  GTAAGAAATG  CTAAAGACAC  AGCTCATACA  420
421   AAAGCAGAAC  GGAATATTCT  GGAGGAAGTA  AAACATCCCT  TCATTGTGGA  TTTAATTTAT  480
481   GCCTTTCAGA  CCGGTGGAAA  ACTCTACCTC  ATCCTTGAGT  ATCTCAGCGG  AGGAGAACTA  540
541   TTTATGCAGT  TAGAAAGAGA  GGGAATATTT  ATGGAAGACA  CAGCTTGCTT  TTACTTGGCA  600
601   GAAATCTCCA  TGGCTTTGGG  GCATTTACAT  CAAAAGGGGA  TCATCTACAG  AGACCTGAAG  660
661   CCGGAGAATA  TCATGCTTAA  TCACCAAGGT  CATGTGAAAC  TAACAGACTT  TGGACTATGC  720
721   AAAGAATCTA  TTCATGATGG  AACAGTCACA  CACACATTTT  GTGGAACAAT  AGAATACATG  780
781   GCCCCTGAAA  TCTTGATGAG  AAGTGGCCAT  AATCGTGCTG  TGGATTGGTG  GAGTTTGGGA  840
841   GCATTAATGT  ATGACATGCT  GACTGGAGCA  CCTCCATTCA  CTGGGGAGAA  TAGAAAGAAA  900
901   ACAATTGACA  AAATCCTCAA  GTGTAAACTC  AATTTGCCTC  CCTACCTCAC  ACAAGAAGCC  960
961   AGAGATCTGC  TTAAAAAGCT  GCTAAAAAGA  AACGCTGCTT  CTCGTCTTGG  AGCTGGTCCT  1020
1021  GGGGATGCTG  GAGAAGTTCA  GGCTCATCCA  TTCTTCAGAC  ACATTAACTG  GGAAGAACTG  1080
1081  CTGGCTCGGA  AAGTGGAGCC  TCCTTTTAAA  CCTCTGTTGC  AATCTGAAGA  GGATGTGAGT  1140
1141  CAGTTTGATT  CAAAGTTTAC  ACGTCAGACA  CCTGTTGACA  GCCCAGATGA  CTCAACTCTC  1200
1201  AGTGAAAGTG  CCAACCAGGT  TTTTCTGGGT  TTTACATATG  TGGCTCCATC  TGTACTTGAA  1260
1261  AGTGTGAAAG  AAAAGTTTTC  CTTTGAACCA  AAAATCCGAT  CACCTCGAAG  ATTTATTGGC  1320
1321  AGCCCGCGAA  CACCTGTGAG  CCCAGTCAAA  TTTTCTCCTG  GGGATTTCTG  GGGAAGAGGT  1380
1381  GCTTCAGCCA  GCACAGCAAA  TCCTCAGACA  CCTGTGGAAT  ACCCAATGGA  AACAAGTGGA  1440
1441  ATAGAGCAGA  TGGATGTGAC  GATGAGTGGG  GAAGCATCAG  CACCACTTCC  AATACGACAG  1500
1501  CCAAACTCCG  GGCCATACAA  AAAACAAGCT  TTTCCCATGA  TCTCCAAACG  GCCAGAGCAC  1560
1561  CTGCGTATGA  ATCTATGA  1578

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mal-0893Mandrillus leucophaeus99.810.01089
LLPS-Paa-2025Papio anubis99.810.01089
LLPS-Myl-1220Myotis lucifugus99.810.01089
LLPS-Caj-0286Callithrix jacchus99.810.01089
LLPS-Aon-1914Aotus nancymaae99.810.01089
LLPS-Maf-2257Macaca fascicularis99.810.01089
LLPS-Chs-0817Chlorocebus sabaeus99.810.01089
LLPS-Nol-0803Nomascus leucogenys99.810.01062
LLPS-Cas-0494Carlito syrichta99.810.01089
LLPS-Mam-1690Macaca mulatta99.810.01089
LLPS-Man-1381Macaca nemestrina99.810.01089
LLPS-Hos-0731Homo sapiens99.810.01089
LLPS-Pat-2026Pan troglodytes99.810.01089
LLPS-Ova-0252Ovis aries99.790.0 992
LLPS-Bot-2699Bos taurus99.620.01087
LLPS-Cea-0019Cercocebus atys99.620.01086
LLPS-Ict-0250Ictidomys tridecemlineatus99.620.01087
LLPS-Caf-2859Canis familiaris99.620.01088
LLPS-Poa-1054Pongo abelii99.620.01088
LLPS-Eqc-1749Equus caballus99.620.01087
LLPS-Otg-0349Otolemur garnettii99.620.01087
LLPS-Fec-0554Felis catus99.620.01088
LLPS-Anp-1262Anas platyrhynchos99.490.0 813
LLPS-Mup-0591Mustela putorius furo99.430.01087
LLPS-Ran-0030Rattus norvegicus99.430.01084
LLPS-Tut-1095Tursiops truncatus99.430.01085
LLPS-Sus-0893Sus scrofa99.430.01085
LLPS-Aim-0691Ailuropoda melanoleuca99.240.01085
LLPS-Mum-1732Mus musculus99.240.01081
LLPS-Urm-0510Ursus maritimus99.240.01085
LLPS-Fud-0920Fukomys damarensis99.050.01080
LLPS-Ora-0278Ornithorhynchus anatinus98.540.0 979
LLPS-Meg-1314Meleagris gallopavo97.70.0 971
LLPS-Gaga-1174Gallus gallus97.610.01020
LLPS-Dio-2287Dipodomys ordii97.390.0 997
LLPS-Mod-2067Monodelphis domestica97.150.01044
LLPS-Tag-1375Taeniopygia guttata97.010.01014
LLPS-Pes-1910Pelodiscus sinensis96.410.01009
LLPS-Sah-1197Sarcophilus harrisii95.070.01021
LLPS-Anc-1275Anolis carolinensis94.440.0 991
LLPS-Fia-1713Ficedula albicollis94.380.0 976
LLPS-Cap-1558Cavia porcellus94.210.0 989
LLPS-Lac-0467Latimeria chalumnae93.070.0 832
LLPS-Pap-0237Pan paniscus92.280.0 972
LLPS-Xet-0418Xenopus tropicalis90.10.0 971
LLPS-Leo-0473Lepisosteus oculatus86.250.0 887
LLPS-Scf-3715Scleropages formosus86.180.0 823
LLPS-Rhb-2529Rhinopithecus bieti86.10.0 872
LLPS-Dar-1502Danio rerio84.580.0 879
LLPS-Asm-0886Astyanax mexicanus84.390.0 876
LLPS-Tar-0904Takifugu rubripes83.860.0 860
LLPS-Icp-0568Ictalurus punctatus83.790.0 864
LLPS-Gaa-0745Gasterosteus aculeatus83.40.0 855
LLPS-Orn-1506Oreochromis niloticus83.170.0 865
LLPS-Orl-3449Oryzias latipes82.970.0 865
LLPS-Scm-1710Scophthalmus maximus82.480.0 857
LLPS-Pof-0580Poecilia formosa81.980.0 835
LLPS-Xim-1284Xiphophorus maculatus80.630.0 836
LLPS-Ten-1095Tetraodon nigroviridis79.250.0 841
LLPS-Gog-3627Gorilla gorilla73.360.0 669
LLPS-Drm-0721Drosophila melanogaster72.830.0 565
LLPS-Cae-0265Caenorhabditis elegans68.381e-174 511
LLPS-Mea-3020Mesocricetus auratus66.060.0 647