• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Tra-1596
TUBA-2A

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tubulin alpha chain
Gene Name: TUBA-2A, TUBA-2B, TUBA-2D
Ensembl Gene: TraesCS1A02G350200
Ensembl Protein: TraesCS1A02G350200.3
Organism: Triticum aestivum
Taxa ID: 4565
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRECISIHIG  QAGIQVGNAC  WELYCLEHGI  QPDGQMPGDK  TVGGGDDAFN  TFFSETGAGK  60
61    HVPRAVFVDL  EPTVIDEVRT  GAYRQLFHPE  QLISGKEDAA  NNFARGHYTI  GKEIVDLCLD  120
121   RIRKLSDNCT  GLQGFLVFNA  VGGGTGSGLG  SLLLERLSVD  YGKKSKLGFT  VYPSPQVSTS  180
181   VVEPYNSVLS  THSLLEHTDV  SILLDNEAIY  DICRRSLDIE  RPTYTNLNRL  VSQVISSLTA  240
241   SLRFDGALNV  DVNEFQTNLV  PYPRIHFMLS  SYAPVISAEK  AYHEQLSVAE  ITNSAFEPSS  300
301   MMAKCDPRHG  KYMACCLMYR  GDVVPKDVNA  AVATIKTKRT  IQFVDWCPTG  FKCGINYQPP  360
361   GVVPGGDLAK  VQRAVCMISN  STSVVEVFSR  IDHKFDLMYA  KRAFVHWYVG  EGMEEGEFSE  420
421   AREDLAALEK  DYEEVGAEFD  EGEDGDEGDE  Y  451
Nucleotide CDS Sequence (FASTA)
1     ATGAGGGAGT  GCATCTCGAT  CCACATCGGC  CAGGCCGGCA  TCCAGGTCGG  GAACGCGTGC  60
61    TGGGAGCTCT  ACTGCCTCGA  GCATGGCATT  CAGCCTGATG  GCCAGATGCC  CGGTGACAAG  120
121   ACCGTTGGGG  GAGGTGATGA  TGCTTTCAAC  ACCTTCTTCA  GCGAGACTGG  GGCTGGGAAG  180
181   CACGTCCCCC  GTGCTGTCTT  CGTAGATCTC  GAGCCCACTG  TGATTGATGA  GGTGAGGACT  240
241   GGCGCTTACC  GCCAGCTCTT  CCACCCTGAG  CAGCTTATCA  GTGGCAAGGA  GGATGCAGCC  300
301   AACAACTTCG  CCCGTGGTCA  TTACACCATT  GGCAAGGAGA  TTGTTGATCT  GTGCCTTGAC  360
361   CGTATCAGGA  AGCTTTCAGA  CAACTGCACT  GGTCTCCAGG  GATTCCTTGT  CTTCAACGCT  420
421   GTTGGAGGTG  GAACTGGCTC  TGGCCTTGGT  TCTCTTCTGC  TGGAGCGCCT  CTCTGTTGAC  480
481   TATGGAAAGA  AGTCCAAGCT  TGGGTTCACA  GTGTACCCAT  CACCCCAGGT  CTCCACCTCT  540
541   GTTGTTGAGC  CATACAACAG  TGTCCTGTCC  ACCCACTCCC  TCCTTGAGCA  CACTGATGTG  600
601   TCTATCCTTC  TTGACAATGA  GGCCATCTAT  GACATCTGCC  GCCGCTCCCT  TGACATTGAG  660
661   CGCCCAACAT  ACACCAACCT  CAACAGGCTT  GTTTCTCAGA  CCAACTTGGT  GCCCTACCCG  720
721   AGGATCCACT  TCATGCTTTC  CTCCTATGCC  CCAGTGATCT  CAGCTGAGAA  GGCCTACCAT  780
781   GAGCAGCTGT  CTGTTGCTGA  GATCACCAAC  AGCGCCTTTG  AGCCTTCATC  TATGATGGCC  840
841   AAGTGTGACC  CCCGCCACGG  CAAGTACATG  GCCTGCTGTC  TCATGTACCG  TGGTGATGTT  900
901   GTTCCCAAGG  ATGTCAACGC  TGCTGTGGCC  ACCATCAAGA  CCAAGCGCAC  TATCCAGTTT  960
961   GTTGACTGGT  GCCCCACTGG  CTTCAAGTGT  GGTATCAACT  ACCAGCCACC  AGGTGTTGTC  1020
1021  CCAGGTGGTG  ACCTTGCCAA  GGTCCAGAGG  GCTGTGTGCA  TGATCTCCAA  CTCCACCAGT  1080
1081  GTCGTCGAGG  TCTTCTCCCG  CATTGACCAC  AAGTTTGACC  TCATGTACGC  CAAGCGTGCC  1140
1141  TTCGTCCACT  GGTACGTCGG  TGAGGGCATG  GAGGAGGGAG  AGTTCTCTGA  GGCCCGTGAG  1200
1201  GATCTTGCTG  CCCTGGAGAA  GGACTATGAA  GAAGTTGGTG  CTGAGTTCGA  CGAGGGTGAG  1260
1261  GACGGTGACG  AGGGCGACGA  GTACTAG  1287

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Cytoskeleton
GTP-binding
Microtubule
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Microtubule
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Structural constituent of cytoskeleton
Biological Process
Microtubule-based process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hov-2119Hordeum vulgare100.00.0 863
LLPS-Tru-1941Triticum urartu100.00.0 863
LLPS-Lep-1110Leersia perrieri99.070.0 858
LLPS-Orbr-2152Oryza brachyantha98.840.0 857
LLPS-Met-1864Medicago truncatula98.610.0 855
LLPS-Sob-1031Sorghum bicolor98.610.0 854
LLPS-Orgl-1631Oryza glumaepatula98.380.0 850
LLPS-Glm-2992Glycine max98.380.0 853
LLPS-Orb-2303Oryza barthii98.380.0 850
LLPS-Ori-2327Oryza indica98.380.0 850
LLPS-Orni-0878Oryza nivara98.380.0 850
LLPS-Orr-0647Oryza rufipogon98.380.0 850
LLPS-Orm-1731Oryza meridionalis98.380.0 850
LLPS-Org-2214Oryza glaberrima98.380.0 850
LLPS-Zem-2565Zea mays98.380.0 854
LLPS-Ors-1178Oryza sativa98.380.0 850
LLPS-Via-1000Vigna angularis98.150.0 848
LLPS-Cus-0944Cucumis sativus98.150.0 850
LLPS-Vir-1071Vigna radiata98.150.0 848
LLPS-Thc-0065Theobroma cacao98.150.0 851
LLPS-Prp-2376Prunus persica98.150.0 851
LLPS-Pot-1471Populus trichocarpa98.150.0 852
LLPS-Orp-1555Oryza punctata98.150.0 850
LLPS-Mae-1818Manihot esculenta98.150.0 851
LLPS-Amt-0703Amborella trichopoda98.150.0 852
LLPS-Sol-2173Solanum lycopersicum97.920.0 852
LLPS-Sem-0429Selaginella moellendorffii97.920.0 849
LLPS-Brn-2513Brassica napus97.920.0 849
LLPS-Php-0654Physcomitrella patens97.920.0 850
LLPS-Viv-1837Vitis vinifera97.920.0 847
LLPS-Gor-2538Gossypium raimondii97.920.0 851
LLPS-Art-1057Arabidopsis thaliana97.920.0 849
LLPS-Brd-0075Brachypodium distachyon97.690.0 845
LLPS-Arl-1010Arabidopsis lyrata97.690.0 846
LLPS-Dac-0916Daucus carota97.690.0 847
LLPS-Coc-1608Corchorus capsularis97.690.0 847
LLPS-Bro-2387Brassica oleracea97.690.0 846
LLPS-Brr-2564Brassica rapa97.690.0 846
LLPS-Nia-2478Nicotiana attenuata97.690.0 851
LLPS-Hea-2650Helianthus annuus97.450.0 847
LLPS-Phv-0112Phaseolus vulgaris97.450.0 847
LLPS-Sot-1554Solanum tuberosum96.760.0 842
LLPS-Sei-0199Setaria italica94.910.0 823
LLPS-Chr-1284Chlamydomonas reinhardtii93.060.0 824
LLPS-Osl-0496Ostreococcus lucimarinus92.590.0 823
LLPS-Pes-2445Pelodiscus sinensis89.767e-77 256
LLPS-Bot-0312Bos taurus85.420.0 779
LLPS-Scf-2328Scleropages formosus85.190.0 780
LLPS-Chs-1539Chlorocebus sabaeus85.190.0 778
LLPS-Fud-4403Fukomys damarensis85.190.0 780
LLPS-Asm-0148Astyanax mexicanus85.190.0 780
LLPS-Icp-1141Ictalurus punctatus85.190.0 780
LLPS-Dar-3733Danio rerio85.190.0 780
LLPS-Mal-2039Mandrillus leucophaeus85.150.0 775
LLPS-Paa-2748Papio anubis85.150.0 775
LLPS-Maf-0209Macaca fascicularis85.150.0 775
LLPS-Gog-3093Gorilla gorilla85.150.0 775
LLPS-Poa-3265Pongo abelii85.150.0 776
LLPS-Mam-0805Macaca mulatta85.150.0 775
LLPS-Hos-1672Homo sapiens85.150.0 775
LLPS-Pat-0458Pan troglodytes85.150.0 775
LLPS-Lac-1000Latimeria chalumnae85.150.0 778
LLPS-Orc-3307Oryctolagus cuniculus85.150.0 776
LLPS-Xim-1672Xiphophorus maculatus84.950.0 778
LLPS-Drm-0758Drosophila melanogaster84.950.0 775
LLPS-Dio-2079Dipodomys ordii84.950.0 777
LLPS-Ran-1850Rattus norvegicus84.950.0 777
LLPS-Cii-0592Ciona intestinalis84.950.0 777
LLPS-Mum-4242Mus musculus84.950.0 778
LLPS-Sus-3651Sus scrofa84.950.0 777
LLPS-Ten-2970Tetraodon nigroviridis84.950.0 778
LLPS-Cap-3401Cavia porcellus84.950.0 778
LLPS-Gaga-2212Gallus gallus84.950.0 777
LLPS-Anc-2036Anolis carolinensis84.950.0 777
LLPS-Pap-4472Pan paniscus84.950.0 778
LLPS-Urm-3000Ursus maritimus84.950.0 778
LLPS-Mod-1950Monodelphis domestica84.950.0 778
LLPS-Fec-0466Felis catus84.950.0 778
LLPS-Tut-0018Tursiops truncatus84.920.0 775
LLPS-Myl-1343Myotis lucifugus84.920.0 775
LLPS-Ora-0959Ornithorhynchus anatinus84.920.0 776
LLPS-Leo-3078Lepisosteus oculatus84.920.0 776
LLPS-Aon-0811Aotus nancymaae84.920.0 775
LLPS-Caj-2133Callithrix jacchus84.920.0 776
LLPS-Caf-1216Canis familiaris84.920.0 776
LLPS-Cas-1839Carlito syrichta84.920.0 776
LLPS-Meg-1613Meleagris gallopavo84.920.0 776
LLPS-Man-1838Macaca nemestrina84.920.0 775
LLPS-Mup-0654Mustela putorius furo84.720.0 776
LLPS-Cea-1318Cercocebus atys84.720.0 776
LLPS-Eqc-0069Equus caballus84.720.0 776
LLPS-Nol-2673Nomascus leucogenys84.720.0 776
LLPS-Ict-2143Ictidomys tridecemlineatus84.720.0 776
LLPS-Pof-3465Poecilia formosa84.720.0 776
LLPS-Scm-0904Scophthalmus maximus84.720.0 777
LLPS-Loa-1707Loxodonta africana84.720.0 770
LLPS-Fia-2663Ficedula albicollis84.720.0 777
LLPS-Ere-0436Erinaceus europaeus84.690.0 774
LLPS-Aim-3885Ailuropoda melanoleuca84.690.0 771
LLPS-Anp-1080Anas platyrhynchos84.690.0 772
LLPS-Otg-3152Otolemur garnettii84.690.0 773
LLPS-Mea-1952Mesocricetus auratus84.490.0 772
LLPS-Xet-0144Xenopus tropicalis84.490.0 776
LLPS-Ova-0174Ovis aries84.260.0 776
LLPS-Orl-0238Oryzias latipes84.260.0 775
LLPS-Tar-1284Takifugu rubripes83.80.0 772
LLPS-Gaa-2776Gasterosteus aculeatus83.560.0 771
LLPS-Cis-1540Ciona savignyi83.560.0 772