• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Tra-0906

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Delta-1-pyrroline-5-carboxylate synthase
Ensembl Gene: TraesCS1B02G290600
Ensembl Protein: TraesCS1B02G290600.1
Organism: Triticum aestivum
Taxa ID: 4565
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAGADPNRSF  MKDVKRIIIK  VGTAVITRND  GRLALGRIGA  LCEQVKDLNA  QGYEVIMVTS  60
61    GAVGVGRQRL  RYRKLVNSSF  ADLQKPQMEL  DGKACAAVGQ  SGLMALYDML  FTQLDVSSSQ  120
121   LLVTDSDFDN  SNFRERLRET  VESLLELRVI  PIFNENDAIS  TRKAPYEDSS  GIFWDNDSLA  180
181   GLLALELKAD  LLVLLSDVDG  LYSGPPSEPS  SKLIHTYIKE  KHYHEITFGD  KSRVGRGGMT  240
241   AKVQAAVWAS  TGGVPVVITS  GCASQSLVKV  LRGEKIGTLF  HKNASLWEPS  KETSVREMAV  300
301   AARDCSRRLQ  NLSSEERKKI  LLDVADALEA  NEDLIRSENE  ADLAAAHEAG  YESALVSRLT  360
361   LKPGKIASLA  KSVRTLANME  DPINEILKRT  EVADGLVLEK  TSCPLGVLLI  IFESRPDALV  420
421   QIASLAIRSG  NGLLLKGGKE  AMRSNAILHK  VITNAIPDNV  GEKLIGLITT  RDEIADLLKH  480
481   DDVIDLVIPR  GSNKLVAQIK  SSTKIPVLGH  ADGVCHVYID  KSADMDMAKR  IVMDAKIDYP  540
541   AACNAMETLL  VHKDLMKTPE  LNDILVALKT  AGVNLYCGPV  AHKVLGYPKA  DSLHLEYSSM  600
601   ACTVEIVDDV  QSAIDHIHRY  GSAHTDCVVT  TDDKVAETFL  RQVDSAAVLY  NASTRFSDGA  660
661   RFGLGAEVGI  STGRIHARGP  VGVEGLLTTR  WLLRGKGQVV  NGDKDVEYTH  KSLPLQ  716
Nucleotide CDS Sequence (FASTA)
1     ATGACAGCTA  AAGTCCAAGC  TGCTGTGTGG  GCTTCAACGG  GTGGTGTACC  TGTTGTTATT  60
61    ACAAGTGGAT  GTGCATCTCA  GAGCCTTGTT  AAAGTTCTCC  GTGGGGAAAA  AATTGGTACT  120
121   CTTTTTCATA  AAAATGCAAG  TTTGTGGGAA  CCATCCAAGG  AGACCAGTGT  CCGTGAAATG  180
181   GCTGTTGCTG  CACGGGATTG  TTCAAGGCGT  CTACAGAATT  TGTCATCAGA  GGAGCGCAAG  240
241   AAAATATTGT  TAGATGTTGC  GGATGCTTTA  GAGGCAAATG  AGGATTTAAT  TAGATCCGAG  300
301   AATGAAGCAG  ATTTAGCAGC  AGCACATGAG  GCTGGGTATG  AGAGTGCTTT  GGTTTCTAGA  360
361   TTGACTCTGA  AACCAGGAAA  GATAGCAAGC  CTTGCCAAAT  CTGTTCGCAC  TCTTGCGAAT  420
421   ATGGAAGACC  CTATTAACGA  GATACTGAAA  AGGACAGAGG  TTGCTGATGG  TTTAGTTCTT  480
481   GAGAAAACAT  CTTGCCCTTT  GGGTGTTCTA  TTGATTATTT  TTGAGTCCCG  ACCTGATGCC  540
541   TTAGTCCAGA  TTGCGTCTTT  AGCCATTCGA  AGTGGTAATG  GTCTTCTCCT  AAAAGGTGGA  600
601   AAAGAAGCAA  TGAGATCAAA  CGCAATATTG  CATAAGGTTA  TAACCAATGC  TATTCCTGAC  660
661   AATGTTGGCG  AAAAATTGAT  TGGCCTTATT  ACAACTAGAG  ATGAAATTGC  GGATTTGCTA  720
721   AAGCATGATG  ATGTCATTGA  TCTTGTCATT  CCAAGAGGGA  GTAATAAGCT  TGTTGCTCAA  780
781   ATCAAATCAT  CAACAAAGAT  TCCTGTTCTT  GGCCATGCTG  ATGGTGTTTG  TCATGTATAT  840
841   ATTGACAAAT  CAGCAGACAT  GGATATGGCA  AAACGTATTG  TGATGGATGC  AAAAATTGAT  900
901   TACCCAGCTG  CCTGCAACGC  AATGACGTTG  CTTGTTCATA  AAGATCTTAT  GAAGACTCCA  960
961   GAACTCAATG  ACATACTAGT  AGCACTCAAG  ACAGCAGGAG  TTAATCTTTA  TTGTGGGCCT  1020
1021  GTTGCGCATA  AAGTATTGGG  CTACCCAAAA  GCAGATTCAT  TACATCTGGA  GTACAGTTCT  1080
1081  ATGGCTTGCA  CAGTTGAGAT  AGTTGATGAT  GTACAATCAG  CAATTGACCA  TATACATCGC  1140
1141  TATGGAAGTG  CACATACAGA  CTGTGTGGTC  ACTACAGATG  ATAAAGTAGC  AGAGACCTTT  1200
1201  CTACGTCAAG  TTGATAGTGC  TGCCGTATTA  TACAACGCGA  GTACAAGATT  CTCCGATGGT  1260
1261  GCTCGTTTTG  GACTCGGTGC  TGAGGTTGGC  ATAAGTACAG  GCCGTATACA  TGCACGTGGA  1320
1321  CCTGTGGGTG  TTGAAGGTCT  TTTAACTACA  CGATGGCTCT  TACGAGGGAA  AGGGCAAGTG  1380
1381  GTGAATGGTG  ACAAGGATGT  TGAGTACACC  CATAAGAGCC  TTCCTTTGCA  ATGA  1434

▼ KEYWORD

ID
Family
Amino-acid biosynthesis
ATP-binding
Complete proteome
Kinase
NADP
Nucleotide-binding
Oxidoreductase
Proline biosynthesis
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
ATP binding
Molecular Function
Glutamate 5-kinase activity
Molecular Function
Glutamate-5-semialdehyde dehydrogenase activity
Biological Process
L-proline biosynthetic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hov-2027Hordeum vulgare97.770.01377
LLPS-Brd-0533Brachypodium distachyon93.30.01316
LLPS-Org-1563Oryza glaberrima88.130.01246
LLPS-Ors-1565Oryza sativa87.990.01246
LLPS-Orbr-0083Oryza brachyantha87.430.01238
LLPS-Sei-0414Setaria italica87.290.01237
LLPS-Lep-1550Leersia perrieri86.910.01211
LLPS-Sob-0818Sorghum bicolor86.870.01234
LLPS-Orb-1212Oryza barthii86.780.01237
LLPS-Orp-0456Oryza punctata86.780.01243
LLPS-Orm-1110Oryza meridionalis86.50.01237
LLPS-Ori-2343Oryza indica84.70.01233
LLPS-Orni-1997Oryza nivara83.580.01225
LLPS-Orgl-0373Oryza glumaepatula83.580.01226
LLPS-Orr-1694Oryza rufipogon83.440.01222
LLPS-Zem-2463Zea mays79.950.01192
LLPS-Amt-0609Amborella trichopoda78.020.01066
LLPS-Pot-0570Populus trichocarpa77.790.01082
LLPS-Tru-0872Triticum urartu77.160.01052
LLPS-Viv-1246Vitis vinifera76.820.01092
LLPS-Mae-2552Manihot esculenta76.260.01080
LLPS-Thc-0137Theobroma cacao76.120.01083
LLPS-Coc-1482Corchorus capsularis76.040.01078
LLPS-Nia-2573Nicotiana attenuata76.020.01080
LLPS-Gor-2177Gossypium raimondii75.880.01070
LLPS-Mua-0543Musa acuminata75.10.01019
LLPS-Glm-1753Glycine max74.720.01052
LLPS-Sot-2231Solanum tuberosum74.440.01056
LLPS-Sol-2417Solanum lycopersicum74.410.01055
LLPS-Met-1643Medicago truncatula74.30.01018
LLPS-Prp-0668Prunus persica74.230.01038
LLPS-Cus-1917Cucumis sativus73.60.01032
LLPS-Bro-2253Brassica oleracea73.180.01031
LLPS-Hea-0257Helianthus annuus72.770.01030
LLPS-Arl-1896Arabidopsis lyrata72.730.01028
LLPS-Brn-2029Brassica napus72.630.01022
LLPS-Art-2608Arabidopsis thaliana72.590.01025
LLPS-Php-2087Physcomitrella patens72.430.01026
LLPS-Brr-1333Brassica rapa72.210.01015
LLPS-Via-2407Vigna angularis72.060.0 976
LLPS-Dac-1579Daucus carota71.890.01027
LLPS-Phv-0399Phaseolus vulgaris71.870.01016
LLPS-Vir-1769Vigna radiata71.750.0 997
LLPS-Sem-0840Selaginella moellendorffii68.460.0 958
LLPS-Osl-1207Ostreococcus lucimarinus60.03e-166 492
LLPS-Chr-0871Chlamydomonas reinhardtii56.095e-168 505
LLPS-Dio-3399Dipodomys ordii52.365e-85 290
LLPS-Drm-2108Drosophila melanogaster47.40.0 592
LLPS-Pof-3959Poecilia formosa47.350.0 603
LLPS-Gaa-0600Gasterosteus aculeatus47.280.0 602
LLPS-Scf-2363Scleropages formosus47.210.0 598
LLPS-Myl-0232Myotis lucifugus47.210.0 600
LLPS-Scm-3551Scophthalmus maximus47.210.0 599
LLPS-Man-1353Macaca nemestrina47.140.0 585
LLPS-Fec-0116Felis catus47.140.0 598
LLPS-Xim-3315Xiphophorus maculatus47.080.0 602
LLPS-Sah-2346Sarcophilus harrisii47.00.0 596
LLPS-Gog-4762Gorilla gorilla47.00.0 597
LLPS-Hos-1328Homo sapiens47.00.0 597
LLPS-Pat-4948Pan troglodytes47.00.0 597
LLPS-Pap-0804Pan paniscus47.00.0 597
LLPS-Orl-3279Oryzias latipes46.940.0 600
LLPS-Sus-2581Sus scrofa46.870.0 597
LLPS-Mum-4260Mus musculus46.870.0 593
LLPS-Mea-2783Mesocricetus auratus46.870.0 598
LLPS-Caj-1305Callithrix jacchus46.870.0 595
LLPS-Bot-4463Bos taurus46.870.0 594
LLPS-Tut-1806Tursiops truncatus46.870.0 593
LLPS-Mup-0433Mustela putorius furo46.870.0 595
LLPS-Aim-3424Ailuropoda melanoleuca46.870.0 596
LLPS-Ran-2855Rattus norvegicus46.870.0 595
LLPS-Loa-0645Loxodonta africana46.870.0 598
LLPS-Urm-3575Ursus maritimus46.870.0 596
LLPS-Orc-3757Oryctolagus cuniculus46.870.0 595
LLPS-Poa-1734Pongo abelii46.870.0 593
LLPS-Caf-4550Canis familiaris46.870.0 595
LLPS-Eqc-3283Equus caballus46.870.0 597
LLPS-Ict-3087Ictidomys tridecemlineatus46.812e-162 493
LLPS-Leo-3922Lepisosteus oculatus46.80.0 594
LLPS-Mod-1684Monodelphis domestica46.790.0 588
LLPS-Tar-3417Takifugu rubripes46.740.0 608
LLPS-Cea-0043Cercocebus atys46.730.0 594
LLPS-Aon-4385Aotus nancymaae46.730.0 593
LLPS-Paa-0445Papio anubis46.730.0 593
LLPS-Ova-1887Ovis aries46.730.0 593
LLPS-Rhb-2897Rhinopithecus bieti46.730.0 593
LLPS-Otg-3619Otolemur garnettii46.730.0 597
LLPS-Cas-3640Carlito syrichta46.730.0 595
LLPS-Ora-1569Ornithorhynchus anatinus46.722e-164 494
LLPS-Maf-4249Macaca fascicularis46.590.0 592
LLPS-Mam-1852Macaca mulatta46.590.0 592
LLPS-Dar-4013Danio rerio46.540.0 584
LLPS-Ten-1863Tetraodon nigroviridis46.540.0 603
LLPS-Fud-1050Fukomys damarensis46.460.0 592
LLPS-Cap-0823Cavia porcellus46.460.0 593
LLPS-Fia-3065Ficedula albicollis46.40.0 596
LLPS-Cae-1231Caenorhabditis elegans46.350.0 589
LLPS-Xet-0482Xenopus tropicalis46.340.0 593
LLPS-Tag-1716Taeniopygia guttata46.270.0 585
LLPS-Gaga-3623Gallus gallus46.130.0 592
LLPS-Meg-0992Meleagris gallopavo46.070.0 587
LLPS-Orn-3127Oreochromis niloticus46.00.0 596
LLPS-Lac-4058Latimeria chalumnae45.990.0 596
LLPS-Pes-0848Pelodiscus sinensis45.860.0 588
LLPS-Anc-1242Anolis carolinensis45.470.0 555
LLPS-Asm-3098Astyanax mexicanus45.180.0 580
LLPS-Fus-1628Fusarium solani45.181e-105 337
LLPS-Lem-0731Leptosphaeria maculans45.082e-104 333
LLPS-Gas-1253Galdieria sulphuraria44.877e-108 342
LLPS-Cii-2196Ciona intestinalis44.770.0 551
LLPS-Icp-3519Ictalurus punctatus44.730.0 565
LLPS-Trr-1553Trichoderma reesei44.696e-94 306
LLPS-Trv-0079Trichoderma virens44.314e-99 319
LLPS-Anp-3050Anas platyrhynchos44.223e-53 193
LLPS-Asfu-1352Aspergillus fumigatus44.014e-106 338
LLPS-Coo-0358Colletotrichum orbiculare43.821e-107 342
LLPS-Fuo-0891Fusarium oxysporum43.764e-102 327
LLPS-Kop-0074Komagataella pastoris43.684e-105 335
LLPS-Mal-2783Mandrillus leucophaeus43.543e-171 517
LLPS-Fuv-0074Fusarium verticillioides43.533e-102 328
LLPS-Beb-1560Beauveria bassiana43.363e-95 310
LLPS-Asf-0482Aspergillus flavus43.352e-103 329
LLPS-Chc-0795Chondrus crispus43.262e-101 325
LLPS-Cogr-1490Colletotrichum graminicola43.242e-104 333
LLPS-Ast-1275Aspergillus terreus43.217e-107 340
LLPS-Cog-0099Colletotrichum gloeosporioides43.163e-104 333
LLPS-Nec-1025Neurospora crassa43.121e-98 318
LLPS-Cym-0557Cyanidioschyzon merolae42.962e-103 332
LLPS-Phn-0769Phaeosphaeria nodorum42.924e-98 317
LLPS-Dos-0087Dothistroma septosporum42.929e-104 332
LLPS-Blg-1583Blumeria graminis42.692e-101 325
LLPS-Scs-0356Sclerotinia sclerotiorum42.669e-102 326
LLPS-Gag-0371Gaeumannomyces graminis42.599e-95 308
LLPS-Nol-1609Nomascus leucogenys42.590.0 547
LLPS-Mao-0111Magnaporthe oryzae42.523e-103 330
LLPS-Pyt-0838Pyrenophora teres42.528e-101 324
LLPS-Aso-1403Aspergillus oryzae42.422e-104 333
LLPS-Ved-1505Verticillium dahliae42.351e-101 327
LLPS-Nef-1590Neosartorya fischeri42.29e-106 337
LLPS-Scp-0445Schizosaccharomyces pombe42.186e-103 330
LLPS-Tum-1615Tuber melanosporum42.085e-99 319
LLPS-Chs-0866Chlorocebus sabaeus42.078e-78 265
LLPS-Asn-1305Aspergillus nidulans42.052e-105 336
LLPS-Pytr-1239Pyrenophora triticirepentis42.047e-101 324
LLPS-Asg-1324Ashbya gossypii41.931e-103 331
LLPS-Scc-1081Schizosaccharomyces cryophilus41.92e-104 333
LLPS-Zyt-1573Zymoseptoria tritici41.724e-97 314
LLPS-Asc-0541Aspergillus clavatus41.675e-106 338
LLPS-Usm-1401Ustilago maydis41.369e-88 290
LLPS-Scj-1006Schizosaccharomyces japonicus41.121e-104 334
LLPS-Sac-1238Saccharomyces cerevisiae41.061e-105 337
LLPS-Yal-1433Yarrowia lipolytica40.832e-102 328
LLPS-Abg-0441Absidia glauca40.615e-99 319
LLPS-Crn-0132Cryptococcus neoformans40.323e-95 310
LLPS-Spr-1262Sporisorium reilianum40.233e-87 289
LLPS-Map-0221Magnaporthe poae39.224e-32 129
LLPS-Miv-0125Microbotryum violaceum38.813e-84 280
LLPS-Pug-1249Puccinia graminis38.026e-97 314
LLPS-Mel-1151Melampsora laricipopulina37.612e-90 298
LLPS-Put-1165Puccinia triticina34.227e-21 100
LLPS-Asni-1102Aspergillus niger31.668e-1787.4