• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sot-2231
102594541

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Delta-1-pyrroline-5-carboxylate synthase
Gene Name: 102594541
Ensembl Gene: PGSC0003DMG402026767
Ensembl Protein: PGSC0003DMT400068829
Organism: Solanum tuberosum
Taxa ID: 4113
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDSADPARAF  VKDVKRIIIK  VGTAVVTRGD  GRLALGRMGS  LCEQIRELTS  QGFEVILVTS  60
61    GAVGVGRQRL  RYRKLINSSF  ADLQKPQGDL  DGKACAAVGQ  NGLMALYDTL  FSQLDVTSAQ  120
121   LMVTDNDFRD  PDFRRQLNET  VNSLLCLKVV  PIFNENDAIS  TRKAPYEDSS  GIFWDNDSLA  180
181   ALLAMELKAD  LLVLLSDVEG  LYTGPPSDPQ  SELIHTYVKE  KHEGLITFGD  KSRVGRGGMT  240
241   AKVKAAVYAA  YAGIPVVITS  GFANNNIIKA  LDGQRVGTLF  HREAIKWASI  GDFDAREMAV  300
301   SARECARRLQ  TLSSQERSKI  LLDIADALEA  KEEEILAENE  ADVAAAQQSG  YENSLISRLA  360
361   MKPGKISSLA  NSVRVLANMD  EPVGRILKRT  ELADGIILEK  TSSPLGVLLI  IFESRPDALV  420
421   QIASLAVRSG  NGLLLKGGKE  AKRSNAILHK  VITSSIPPTV  GERLIGLVTS  REEIPELLKL  480
481   DDVIDLVIPR  GSNKLVSQIK  AATKIPVLGH  ADGICHVFID  KSADLDMAKR  IVLDAKTDYP  540
541   AACNAMETLL  VHEDLVQTGG  LNDLILELQV  KGVSLFGGPK  ASSVLSIPEA  NSFHHEYGAL  600
601   ACTVEIVEDV  NTAIEHIHRH  GSAHTDSIIT  EDKEVAELFL  RQVDSAAVLH  NASTRFSDGF  660
661   RFGLGAEVGI  STSRIHARGP  VGVEGLLTTR  WLARGSGQVV  DGDKEIVYTH  RDLNLEA  717
Nucleotide CDS Sequence (FASTA)
1     ATGCTTATGT  GTACCTCACT  CGTTGACAGT  GCTCACACTG  ATAGCATCAT  TACTGAAGAC  60
61    AAAGAAGTTG  CTGAACTGTT  TTTACGTCAA  GTTGACAGTG  CTGCTGTACT  TCATAATGCA  120
121   AGCACAAGAT  TTAGTGATGG  GTTCCGCTTT  GGACTTGGTG  CAGAGGTGGG  GATTAGTACA  180
181   AGTCGGATTC  ATGCTCGTGG  TCCAGTTGGA  GTTGAGGGAT  TGCTGACAAC  TAGATGGCTT  240
241   GCAAGGGGAT  CTGGACAAGT  TGTTGATGGT  GATAAAGAAA  TTGTATACAC  TCACAGAGAC  300
301   CTTAATCTGG  AGGCTTGA  318

▼ KEYWORD

ID
Family
Amino-acid biosynthesis
ATP-binding
Complete proteome
Kinase
NADP
Nucleotide-binding
Oxidoreductase
Proline biosynthesis
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
ATP binding
Molecular Function
Glutamate 5-kinase activity
Molecular Function
Glutamate-5-semialdehyde dehydrogenase activity
Biological Process
L-proline biosynthetic process

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nia-2573Nicotiana attenuata85.850.01157
LLPS-Sol-2417Solanum lycopersicum84.50.01132
LLPS-Mae-2552Manihot esculenta79.830.01073
LLPS-Amt-0609Amborella trichopoda78.770.01029
LLPS-Pot-0570Populus trichocarpa78.660.01065
LLPS-Viv-1246Vitis vinifera78.630.01106
LLPS-Hea-0257Helianthus annuus78.260.01057
LLPS-Dac-1579Daucus carota77.750.01062
LLPS-Thc-0137Theobroma cacao77.090.01075
LLPS-Glm-1753Glycine max77.00.01059
LLPS-Gor-2177Gossypium raimondii76.940.01060
LLPS-Coc-1482Corchorus capsularis76.320.01063
LLPS-Mua-0543Musa acuminata76.290.0 981
LLPS-Bro-2253Brassica oleracea76.150.01017
LLPS-Sei-0414Setaria italica75.840.01059
LLPS-Arl-1896Arabidopsis lyrata75.740.01026
LLPS-Prp-0668Prunus persica75.630.01034
LLPS-Art-2608Arabidopsis thaliana75.60.01025
LLPS-Org-1563Oryza glaberrima75.560.01052
LLPS-Cus-1917Cucumis sativus75.420.01036
LLPS-Orbr-0083Oryza brachyantha75.280.01050
LLPS-Ors-1565Oryza sativa75.140.01048
LLPS-Via-2407Vigna angularis75.110.0 994
LLPS-Lep-1550Leersia perrieri75.070.01027
LLPS-Vir-1769Vigna radiata75.040.01016
LLPS-Brn-2029Brassica napus74.90.01022
LLPS-Hov-2027Hordeum vulgare74.860.01047
LLPS-Brr-1333Brassica rapa74.760.01019
LLPS-Brd-0533Brachypodium distachyon74.760.01046
LLPS-Sob-0818Sorghum bicolor74.440.01047
LLPS-Tra-0906Triticum aestivum74.440.01040
LLPS-Orp-0456Oryza punctata74.380.01046
LLPS-Orb-1212Oryza barthii74.380.01044
LLPS-Orm-1110Oryza meridionalis74.240.01041
LLPS-Phv-0399Phaseolus vulgaris73.990.01019
LLPS-Met-1643Medicago truncatula73.910.01004
LLPS-Tru-0872Triticum urartu72.560.0 971
LLPS-Ori-2343Oryza indica72.480.01037
LLPS-Orgl-0373Oryza glumaepatula71.520.01030
LLPS-Orni-1997Oryza nivara71.520.01029
LLPS-Orr-1694Oryza rufipogon71.390.01027
LLPS-Php-2087Physcomitrella patens71.090.0 962
LLPS-Zem-2463Zea mays70.050.01017
LLPS-Sem-0840Selaginella moellendorffii67.950.0 927
LLPS-Osl-1207Ostreococcus lucimarinus57.865e-145 437
LLPS-Chr-0871Chlamydomonas reinhardtii57.424e-148 454
LLPS-Dio-3399Dipodomys ordii56.351e-76 268
LLPS-Mal-2783Mandrillus leucophaeus51.73e-89 302
LLPS-Mod-1684Monodelphis domestica48.770.0 570
LLPS-Gas-1253Galdieria sulphuraria48.645e-98 316
LLPS-Ran-2855Rattus norvegicus48.150.0 568
LLPS-Mum-4260Mus musculus48.150.0 569
LLPS-Man-1353Macaca nemestrina48.110.0 563
LLPS-Ora-1569Ornithorhynchus anatinus48.034e-153 465
LLPS-Cas-3640Carlito syrichta48.020.0 570
LLPS-Otg-3619Otolemur garnettii48.020.0 569
LLPS-Fec-0116Felis catus48.020.0 569
LLPS-Mup-0433Mustela putorius furo48.020.0 568
LLPS-Aim-3424Ailuropoda melanoleuca48.020.0 568
LLPS-Mea-2783Mesocricetus auratus48.020.0 569
LLPS-Myl-0232Myotis lucifugus47.950.0 571
LLPS-Pap-0804Pan paniscus47.880.0 569
LLPS-Pat-4948Pan troglodytes47.880.0 569
LLPS-Hos-1328Homo sapiens47.880.0 569
LLPS-Ova-1887Ovis aries47.880.0 568
LLPS-Gog-4762Gorilla gorilla47.880.0 569
LLPS-Sus-2581Sus scrofa47.880.0 568
LLPS-Ict-3087Ictidomys tridecemlineatus47.782e-151 464
LLPS-Caf-4550Canis familiaris47.740.0 566
LLPS-Poa-1734Pongo abelii47.740.0 566
LLPS-Eqc-3283Equus caballus47.740.0 567
LLPS-Cap-0823Cavia porcellus47.740.0 568
LLPS-Orc-3757Oryctolagus cuniculus47.740.0 566
LLPS-Rhb-2897Rhinopithecus bieti47.740.0 566
LLPS-Urm-3575Ursus maritimus47.740.0 567
LLPS-Paa-0445Papio anubis47.740.0 566
LLPS-Bot-4463Bos taurus47.740.0 567
LLPS-Tut-1806Tursiops truncatus47.740.0 566
LLPS-Caj-1305Callithrix jacchus47.740.0 567
LLPS-Sah-2346Sarcophilus harrisii47.740.0 566
LLPS-Cea-0043Cercocebus atys47.740.0 566
LLPS-Mam-1852Macaca mulatta47.610.0 566
LLPS-Loa-0645Loxodonta africana47.610.0 566
LLPS-Gaa-0600Gasterosteus aculeatus47.610.0 565
LLPS-Fud-1050Fukomys damarensis47.610.0 565
LLPS-Aon-4385Aotus nancymaae47.610.0 566
LLPS-Maf-4249Macaca fascicularis47.610.0 566
LLPS-Tag-1716Taeniopygia guttata47.550.0 564
LLPS-Gaga-3623Gallus gallus47.550.0 572
LLPS-Fia-3065Ficedula albicollis47.550.0 573
LLPS-Tum-1615Tuber melanosporum47.531e-89 295
LLPS-Drm-2108Drosophila melanogaster47.520.0 576
LLPS-Pof-3959Poecilia formosa47.490.0 567
LLPS-Xet-0482Xenopus tropicalis47.480.0 568
LLPS-Meg-0992Meleagris gallopavo47.480.0 566
LLPS-Scm-3551Scophthalmus maximus47.480.0 571
LLPS-Scf-2363Scleropages formosus47.40.0 569
LLPS-Orl-3279Oryzias latipes47.40.0 572
LLPS-Leo-3922Lepisosteus oculatus47.40.0 564
LLPS-Pes-0848Pelodiscus sinensis47.280.0 566
LLPS-Nec-1025Neurospora crassa47.273e-87 288
LLPS-Xim-3315Xiphophorus maculatus47.210.0 565
LLPS-Tar-3417Takifugu rubripes47.20.0 575
LLPS-Asm-3098Astyanax mexicanus47.070.0 550
LLPS-Ten-1863Tetraodon nigroviridis47.00.0 570
LLPS-Orn-3127Oreochromis niloticus47.00.0 570
LLPS-Dar-4013Danio rerio47.00.0 553
LLPS-Map-0221Magnaporthe poae46.761e-29 122
LLPS-Cae-1231Caenorhabditis elegans46.670.0 571
LLPS-Lac-4058Latimeria chalumnae46.580.0 567
LLPS-Icp-3519Ictalurus punctatus46.451e-177 536
LLPS-Cym-0557Cyanidioschyzon merolae46.454e-93 305
LLPS-Trv-0079Trichoderma virens46.388e-88 290
LLPS-Anc-1242Anolis carolinensis46.326e-177 530
LLPS-Fus-1628Fusarium solani46.233e-91 298
LLPS-Trr-1553Trichoderma reesei46.22e-84 281
LLPS-Cii-2196Ciona intestinalis45.952e-179 537
LLPS-Anp-3050Anas platyrhynchos45.731e-63 222
LLPS-Chc-0795Chondrus crispus45.71e-88 291
LLPS-Nol-1609Nomascus leucogenys45.622e-165 503
LLPS-Scs-0356Sclerotinia sclerotiorum45.534e-90 296
LLPS-Asfu-1352Aspergillus fumigatus45.182e-90 297
LLPS-Coo-0358Colletotrichum orbiculare44.879e-90 295
LLPS-Abg-0441Absidia glauca44.754e-87 288
LLPS-Fuo-0891Fusarium oxysporum44.685e-90 295
LLPS-Nef-1590Neosartorya fischeri44.621e-90 297
LLPS-Blg-1583Blumeria graminis44.591e-83 278
LLPS-Fuv-0074Fusarium verticillioides44.422e-89 294
LLPS-Cog-0099Colletotrichum gloeosporioides44.271e-93 305
LLPS-Pug-1249Puccinia graminis44.27e-89 293
LLPS-Cogr-1490Colletotrichum graminicola44.12e-89 294
LLPS-Ved-1505Verticillium dahliae43.945e-88 290
LLPS-Dos-0087Dothistroma septosporum43.881e-89 295
LLPS-Lem-0731Leptosphaeria maculans43.656e-84 279
LLPS-Asg-1324Ashbya gossypii43.627e-92 300
LLPS-Mao-0111Magnaporthe oryzae43.42e-85 283
LLPS-Beb-1560Beauveria bassiana43.295e-78 264
LLPS-Chs-0866Chlorocebus sabaeus43.221e-79 269
LLPS-Gag-0371Gaeumannomyces graminis43.198e-79 266
LLPS-Asf-0482Aspergillus flavus42.822e-85 281
LLPS-Kop-0074Komagataella pastoris42.763e-88 291
LLPS-Spr-1262Sporisorium reilianum42.713e-73 251
LLPS-Sac-1238Saccharomyces cerevisiae42.134e-93 304
LLPS-Zyt-1573Zymoseptoria tritici41.921e-82 276
LLPS-Usm-1401Ustilago maydis41.882e-73 252
LLPS-Aso-1403Aspergillus oryzae41.885e-86 285
LLPS-Crn-0132Cryptococcus neoformans41.782e-78 265
LLPS-Asn-1305Aspergillus nidulans41.762e-89 294
LLPS-Ast-1275Aspergillus terreus41.693e-90 296
LLPS-Yal-1433Yarrowia lipolytica41.691e-87 288
LLPS-Scj-1006Schizosaccharomyces japonicus41.599e-84 279
LLPS-Scc-1081Schizosaccharomyces cryophilus41.471e-88 292
LLPS-Scp-0445Schizosaccharomyces pombe41.452e-84 281
LLPS-Phn-0769Phaeosphaeria nodorum41.332e-75 257
LLPS-Asc-0541Aspergillus clavatus41.272e-87 288
LLPS-Pytr-1239Pyrenophora triticirepentis39.672e-76 259
LLPS-Pyt-0838Pyrenophora teres39.673e-76 259
LLPS-Miv-0125Microbotryum violaceum39.571e-72 249
LLPS-Mel-1151Melampsora laricipopulina38.51e-75 258
LLPS-Put-1165Puccinia triticina34.366e-27 119
LLPS-Asni-1102Aspergillus niger33.732e-23 107