DrLLPS - Data resource of LLPS

LLPS-Spr-1126
sr15536

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Prefoldin subunit 4
Gene Name:	sr15536
Ensembl Gene:	sr15536
Ensembl Protein:	CBQ69080
Organism:	Sporisorium reilianum
Taxa ID:	999809
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0824	Q9NQP4	Client	Stress granule	39.02	1e-14	70.9

▼ FUNCTION

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	CBQ69080	CBQ69080
UniProt		E6ZPC3, E6ZPC3_SPORE
GeneBank	FQ311434	CBQ69080.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MRMLSEQEAN EIEVTWEDQQ SINAFSRLNS TYSDLLEDLR TGKEEREALD DLAMELELAD 60 61 EDERILYKIA DTFVSLPHPD AMERLEAEQS EADERLAALQ EKLDSYDAQM KQLKVKLYAK 120 121 FGDNINLERD 130

▼ KEYWORD

ID	Family
KW-0143	Chaperone
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005737	Cellular Component	Cytoplasm
GO:0016272	Cellular Component	Prefoldin complex
GO:0015631	Molecular Function	Tubulin binding
GO:0051082	Molecular Function	Unfolded protein binding
GO:0071629	Biological Process	Cytoplasm protein quality control by the ubiquitin-proteasome system
GO:0032968	Biological Process	Positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006457	Biological Process	Protein folding
GO:0007021	Biological Process	Tubulin complex assembly

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Usm-0362	Ustilago maydis	74.62	3e-50	162
LLPS-Trv-1616	Trichoderma virens	51.16	4e-18	80.1
LLPS-Fuo-1291	Fusarium oxysporum	50.77	1e-12	65.5
LLPS-Trr-1379	Trichoderma reesei	50.39	1e-16	76.3
LLPS-Fuv-0013	Fusarium verticillioides	50.39	6e-12	63.2
LLPS-Fus-0186	Fusarium solani	49.23	5e-09	55.1
LLPS-Scs-0570	Sclerotinia sclerotiorum	48.48	6e-18	79.7
LLPS-Abg-1963	Absidia glauca	47.73	1e-18	81.3
LLPS-Cus-0875	Cucumis sativus	47.54	9e-19	81.6
LLPS-Cog-0459	Colletotrichum gloeosporioides	47.33	2e-13	67.4
LLPS-Coo-0771	Colletotrichum orbiculare	47.33	3e-12	64.3
LLPS-Blg-0930	Blumeria graminis	46.15	6e-17	77.0
LLPS-Yal-1172	Yarrowia lipolytica	45.9	3e-16	75.1
LLPS-Cogr-1204	Colletotrichum graminicola	45.8	5e-16	74.3
LLPS-Tum-1043	Tuber melanosporum	45.31	2e-10	58.5
LLPS-Asg-1132	Ashbya gossypii	44.96	2e-17	78.6
LLPS-Nef-1645	Neosartorya fischeri	44.7	1e-14	70.9
LLPS-Asn-1240	Aspergillus nidulans	44.36	2e-14	70.5
LLPS-Asni-1311	Aspergillus niger	43.97	3e-11	61.2
LLPS-Asfu-1120	Aspergillus fumigatus	43.94	1e-13	68.2
LLPS-Asf-1111	Aspergillus flavus	43.94	2e-14	70.1
LLPS-Aso-1545	Aspergillus oryzae	43.94	2e-14	70.1
LLPS-Mao-0290	Magnaporthe oryzae	43.51	5e-14	69.3
LLPS-Gag-0599	Gaeumannomyces graminis	43.51	1e-12	65.5
LLPS-Sei-0189	Setaria italica	43.31	4e-13	66.6
LLPS-Asc-1070	Aspergillus clavatus	43.18	3e-14	69.7
LLPS-Mua-0036	Musa acuminata	43.09	2e-13	67.8
LLPS-Ved-1224	Verticillium dahliae	42.75	1e-13	68.2
LLPS-Map-0361	Magnaporthe poae	42.75	8e-12	63.2
LLPS-Sol-0194	Solanum lycopersicum	42.62	3e-14	69.3
LLPS-Glm-0857	Glycine max	42.62	3e-17	77.4
LLPS-Sot-1864	Solanum tuberosum	42.62	5e-14	68.9
LLPS-Sob-1682	Sorghum bicolor	42.52	3e-12	63.9
LLPS-Zem-1008	Zea mays	42.52	3e-12	63.9
LLPS-Tra-1299	Triticum aestivum	42.52	1e-12	64.7
LLPS-Brd-1247	Brachypodium distachyon	42.52	2e-12	65.1
LLPS-Amt-1754	Amborella trichopoda	42.5	4e-13	66.2
LLPS-Arl-1141	Arabidopsis lyrata	42.31	2e-16	75.1
LLPS-Org-1773	Oryza glaberrima	42.28	9e-15	70.9
LLPS-Kop-1405	Komagataella pastoris	41.86	7e-15	71.2
LLPS-Mae-2038	Manihot esculenta	41.8	8e-16	73.6
LLPS-Viv-1786	Vitis vinifera	41.8	1e-13	67.8
LLPS-Dos-0992	Dothistroma septosporum	41.74	1e-12	65.1
LLPS-Orbr-0764	Oryza brachyantha	41.73	1e-14	70.5
LLPS-Orp-1483	Oryza punctata	41.73	5e-12	63.2
LLPS-Lep-0776	Leersia perrieri	41.73	9e-12	62.8
LLPS-Pyt-0665	Pyrenophora teres	41.67	2e-15	72.8
LLPS-Art-2539	Arabidopsis thaliana	41.54	4e-16	74.7
LLPS-Lem-1166	Leptosphaeria maculans	41.22	7e-15	71.6
LLPS-Sac-1652	Saccharomyces cerevisiae	41.09	1e-13	68.2
LLPS-Nia-2643	Nicotiana attenuata	40.98	1e-12	65.1
LLPS-Phv-1494	Phaseolus vulgaris	40.98	7e-16	73.9
LLPS-Prp-1860	Prunus persica	40.98	2e-12	64.3
LLPS-Dac-1716	Daucus carota	40.98	8e-15	71.2
LLPS-Met-0478	Medicago truncatula	40.98	1e-16	75.9
LLPS-Vir-1750	Vigna radiata	40.98	5e-13	66.2
LLPS-Ors-0557	Oryza sativa	40.94	1e-14	70.5
LLPS-Orr-1947	Oryza rufipogon	40.94	1e-14	70.5
LLPS-Orni-2159	Oryza nivara	40.94	1e-14	70.5
LLPS-Ori-0955	Oryza indica	40.94	1e-14	70.5
LLPS-Orb-2051	Oryza barthii	40.94	1e-14	70.5
LLPS-Orgl-1980	Oryza glumaepatula	40.94	1e-14	70.5
LLPS-Nec-0465	Neurospora crassa	40.91	4e-12	63.9
LLPS-Php-1550	Physcomitrella patens	40.83	3e-14	69.3
LLPS-Pot-0058	Populus trichocarpa	40.68	2e-15	72.4
LLPS-Miv-0200	Microbotryum violaceum	40.3	3e-13	67.0
LLPS-Gor-2486	Gossypium raimondii	40.16	4e-12	63.9
LLPS-Thc-0093	Theobroma cacao	40.16	2e-12	64.3
LLPS-Phn-1100	Phaeosphaeria nodorum	40.15	6e-15	71.6
LLPS-Otg-3147	Otolemur garnettii	40.0	4e-14	69.3
LLPS-Gas-1013	Galdieria sulphuraria	39.83	3e-10	58.2
LLPS-Eqc-2226	Equus caballus	39.67	9e-14	68.9
LLPS-Mel-0245	Melampsora laricipopulina	39.39	8e-12	62.8
LLPS-Scf-3830	Scleropages formosus	39.39	7e-08	51.6
LLPS-Crn-1122	Cryptococcus neoformans	39.37	2e-16	75.9
LLPS-Urm-1268	Ursus maritimus	39.2	4e-14	69.3
LLPS-Mup-0520	Mustela putorius furo	39.2	4e-14	69.3
LLPS-Cap-1942	Cavia porcellus	39.02	3e-13	67.0
LLPS-Caf-3436	Canis familiaris	39.02	1e-13	67.8
LLPS-Caj-3413	Callithrix jacchus	39.02	3e-13	67.0
LLPS-Bot-4393	Bos taurus	39.02	2e-13	67.8
LLPS-Aim-1000	Ailuropoda melanoleuca	38.93	2e-14	70.5
LLPS-Rhb-2346	Rhinopithecus bieti	38.84	3e-13	67.0
LLPS-Hos-0824	Homo sapiens	38.84	3e-13	67.0
LLPS-Pap-3202	Pan paniscus	38.84	3e-13	67.0
LLPS-Pat-3075	Pan troglodytes	38.84	3e-13	67.0
LLPS-Man-3039	Macaca nemestrina	38.84	3e-13	67.0
LLPS-Cas-1783	Carlito syrichta	38.84	3e-13	67.0
LLPS-Nol-1563	Nomascus leucogenys	38.84	3e-13	67.0
LLPS-Ict-1780	Ictidomys tridecemlineatus	38.84	3e-13	67.0
LLPS-Poa-0503	Pongo abelii	38.84	3e-13	67.0
LLPS-Mam-3761	Macaca mulatta	38.84	3e-13	67.0
LLPS-Gog-2862	Gorilla gorilla	38.84	3e-13	67.0
LLPS-Chs-0913	Chlorocebus sabaeus	38.84	3e-13	67.0
LLPS-Mum-3847	Mus musculus	38.84	1e-12	65.1
LLPS-Maf-0988	Macaca fascicularis	38.84	3e-13	67.0
LLPS-Sus-4851	Sus scrofa	38.84	7e-13	65.9
LLPS-Cea-4720	Cercocebus atys	38.84	3e-13	67.0
LLPS-Ran-3092	Rattus norvegicus	38.84	9e-13	65.5
LLPS-Myl-3564	Myotis lucifugus	38.84	1e-12	65.5
LLPS-Paa-0511	Papio anubis	38.84	3e-13	67.0
LLPS-Mal-1386	Mandrillus leucophaeus	38.84	3e-13	67.0
LLPS-Tut-2280	Tursiops truncatus	38.84	2e-13	67.4
LLPS-Fec-1108	Felis catus	38.46	3e-13	67.4
LLPS-Fud-0506	Fukomys damarensis	38.21	2e-13	67.4
LLPS-Ova-4335	Ovis aries	38.21	3e-13	66.6
LLPS-Orc-2826	Oryctolagus cuniculus	38.02	2e-13	67.4
LLPS-Anc-3769	Anolis carolinensis	38.02	6e-15	71.6
LLPS-Mea-0628	Mesocricetus auratus	38.02	5e-12	63.5
LLPS-Aon-3751	Aotus nancymaae	38.02	5e-12	63.5
LLPS-Ere-0177	Erinaceus europaeus	38.02	2e-12	64.3
LLPS-Pes-2069	Pelodiscus sinensis	37.9	9e-14	68.9
LLPS-Hea-0032	Helianthus annuus	37.7	2e-11	61.6
LLPS-Brr-0211	Brassica rapa	37.69	5e-14	68.9
LLPS-Bro-1772	Brassica oleracea	37.69	1e-14	70.5
LLPS-Brn-0641	Brassica napus	37.69	1e-14	70.9
LLPS-Mod-1252	Monodelphis domestica	37.4	3e-13	67.0
LLPS-Dar-0532	Danio rerio	37.4	1e-14	70.9
LLPS-Loa-4550	Loxodonta africana	37.19	1e-12	65.1
LLPS-Sah-4077	Sarcophilus harrisii	37.19	9e-13	65.5
LLPS-Sem-0763	Selaginella moellendorffii	36.92	3e-16	74.7
LLPS-Anp-1715	Anas platyrhynchos	36.89	5e-14	68.9
LLPS-Beb-0542	Beauveria bassiana	36.49	9e-13	65.9
LLPS-Icp-3904	Ictalurus punctatus	36.36	8e-13	65.9
LLPS-Ora-2341	Ornithorhynchus anatinus	36.36	8e-12	63.2
LLPS-Orl-3874	Oryzias latipes	36.36	5e-12	63.5
LLPS-Dio-1802	Dipodomys ordii	36.15	2e-08	53.1
LLPS-Lac-0419	Latimeria chalumnae	36.13	1e-12	65.5
LLPS-Meg-2113	Meleagris gallopavo	36.13	1e-12	65.1
LLPS-Gaga-3000	Gallus gallus	36.13	1e-12	65.5
LLPS-Xet-0864	Xenopus tropicalis	36.07	2e-16	75.5
LLPS-Ast-1155	Aspergillus terreus	35.95	7e-09	54.7
LLPS-Tag-1691	Taeniopygia guttata	35.83	9e-13	65.5
LLPS-Pof-3059	Poecilia formosa	35.54	3e-11	61.2
LLPS-Asm-2967	Astyanax mexicanus	35.54	7e-13	65.9
LLPS-Xim-1001	Xiphophorus maculatus	35.54	3e-11	61.6
LLPS-Leo-3190	Lepisosteus oculatus	34.71	3e-11	61.2
LLPS-Gaa-1447	Gasterosteus aculeatus	34.71	1e-12	65.5
LLPS-Scm-3292	Scophthalmus maximus	33.88	3e-11	61.6
LLPS-Scj-1481	Schizosaccharomyces japonicus	33.61	6e-08	51.6
LLPS-Orn-3808	Oreochromis niloticus	33.06	4e-10	58.2
LLPS-Cii-2259	Ciona intestinalis	33.06	8e-12	62.8
LLPS-Fia-0345	Ficedula albicollis	32.5	2e-09	56.2
LLPS-Tar-1119	Takifugu rubripes	32.23	5e-09	54.7
LLPS-Drm-0856	Drosophila melanogaster	31.97	4e-07	49.7
LLPS-Osl-1460	Ostreococcus lucimarinus	31.9	1e-06	48.1
LLPS-Cae-1871	Caenorhabditis elegans	31.62	2e-07	50.1

LLPS-Spr-1126sr15536

Protein Sequence

Nucleotide Sequence

LLPS-Spr-1126
sr15536