• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sei-0611
101775533

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GPN-loop GTPase
Gene Name: 101775533, SETIT_9G426600v2
Ensembl Gene: SETIT_035985mg
Ensembl Protein: KQK91158
Organism: Setaria italica
Taxa ID: 4555
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-bodyPredicted from orthologs(View)

▼ FUNCTION

Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblKQK91158KQK91158
EnsemblKQK91157KQK91157
UniProtK4AAS8, K4AAS8_SETIT
GeneBankAGNK02006011, CM003536, RCV45108.1
RefSeqXM_004984537.2XP_004984594.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDVDSDPAAT  SKPTQMDLEE  QTDAKGKGKA  EEGSMKSEEL  ADSIGGLSIG  PGRTNFKKKP  60
61    VIIIVIGMAG  TGKTTLMHRL  VCDMQASDKR  GYVVNLDPAV  MTLPFGANID  IRDTVLYKDV  120
121   MKEYGLGPNG  GILTSLNLFA  TKFDEVVSVI  ERRADQLDYV  LVDTPGQIEI  FTWSASGAII  180
181   TEAFASTFPT  VVAYVVDTPR  STSPVTFMSN  MLYACSILYK  TRLPLVLTFN  KVDVAKHEFA  240
241   IEWMQDFEAF  QTALESDKSY  SATYTRSLSL  VLDEFYKNLR  SVGVSAVSGS  GVNTFFEAIE  300
301   ASAKEYMETY  RADLDKRIAE  KERLEAERRK  ENMEKLQRDM  MKSKGQTVVL  STGLKDKNPA  360
361   SDMMDDAEDE  EDEEFEDEFE  KFVDDEDDED  EEDEEVAHFG  F  401
Nucleotide CDS Sequence (FASTA)
1     ATGGACGTCG  ACTCGGACCC  CGCCGCCACG  AGCAAGCCCA  CCCAGATGGA  CCTCGAGGAG  60
61    CAGACGGACG  CGAAGGGGAA  GGGGAAGGCA  GAGGAGGGGA  GCATGAAGAG  CGAGGAGCTC  120
121   GCGGACTCCA  TTGGGGGCCT  CTCTATTGGC  CCGGGGCGCA  CCAATTTCAA  GAAGAAGCCC  180
181   GTGATTATCA  TCGTCATCGG  CATGGCTGGG  ACGGGGAAGA  CGACCTTGAT  GCACCGGTTG  240
241   GTGTGTGATA  TGCAAGCCTC  AGACAAGAGG  GGCTATGTTG  TCAACCTTGA  CCCTGCGGTG  300
301   ATGACACTGC  CATTCGGGGC  TAACATTGAT  ATCCGCGACA  CGGTGCTGTA  TAAGGACGTG  360
361   ATGAAGGAGT  ACGGCCTTGG  TCCCAATGGT  GGCATTCTCA  CCTCGCTCAA  CTTATTTGCC  420
421   ACCAAGTTCG  ATGAGGTTGT  GTCTGTCATT  GAAAGACGTG  CAGATCAACT  GGATTATGTT  480
481   CTGGTGGACA  CTCCTGGGCA  GATTGAGATC  TTCACTTGGT  CGGCTTCGGG  AGCTATCATC  540
541   ACTGAAGCTT  TTGCATCAAC  ATTTCCAACA  GTCGTTGCAT  ATGTTGTTGA  CACACCCAGA  600
601   TCAACAAGCC  CCGTTACTTT  TATGAGCAAT  ATGCTTTATG  CCTGCAGTAT  TCTCTACAAA  660
661   ACCCGCCTCC  CTCTAGTCCT  GACATTCAAC  AAGGTTGATG  TCGCCAAGCA  CGAGTTTGCA  720
721   ATCGAATGGA  TGCAAGACTT  TGAGGCGTTT  CAGACAGCTT  TGGAATCAGA  CAAATCTTAT  780
781   TCCGCTACAT  ATACCCGAAG  CCTCTCTCTG  GTTCTTGACG  AATTCTACAA  GAATCTACGT  840
841   TCTGTTGGAG  TATCCGCAGT  GTCTGGTAGT  GGAGTCAATA  CATTTTTTGA  AGCTATAGAA  900
901   GCAAGCGCCA  AGGAATATAT  GGAAACCTAC  AGGGCTGATC  TTGACAAGAG  GATTGCTGAA  960
961   AAGGAAAGAT  TGGAAGCAGA  ACGCAGGAAA  GAGAACATGG  AAAAATTGCA  GAGAGATATG  1020
1021  ATGAAATCCA  AAGGACAAAC  TGTGGTTCTC  AGCACTGGTT  TGAAGGACAA  AAATCCCGCT  1080
1081  TCAGACATGA  TGGATGATGC  TGAGGACGAA  GAAGATGAGG  AATTTGAGGA  TGAATTCGAA  1140
1141  AAGTTTGTGG  ATGATGAAGA  TGATGAAGAT  GAAGAAGATG  AGGAAGTGGC  TCATTTTGGC  1200
1201  TTTTGA  1206

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
GTP-binding
Hydrolase
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Microtubule
Cellular Component
Nucleus
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Cell division
Biological Process
Embryo development ending in seed dormancy

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sob-1470Sorghum bicolor93.940.0 636
LLPS-Lep-0753Leersia perrieri93.521e-120 358
LLPS-Orp-1220Oryza punctata92.176e-120 356
LLPS-Zem-2576Zea mays90.520.0 646
LLPS-Orbr-0878Oryza brachyantha90.330.0 595
LLPS-Orb-1726Oryza barthii89.613e-71 229
LLPS-Orgl-2217Oryza glumaepatula89.470.0 604
LLPS-Orni-2281Oryza nivara89.470.0 605
LLPS-Ors-1533Oryza sativa89.470.0 605
LLPS-Orr-1432Oryza rufipogon89.20.0 602
LLPS-Ori-2350Oryza indica89.180.0 568
LLPS-Brd-1310Brachypodium distachyon86.990.0 577
LLPS-Mua-2545Musa acuminata86.864e-128 377
LLPS-Hov-1136Hordeum vulgare83.560.0 559
LLPS-Orm-0227Oryza meridionalis81.720.0 550
LLPS-Tra-0963Triticum aestivum78.950.0 576
LLPS-Tru-1417Triticum urartu78.390.0 556
LLPS-Phv-2003Phaseolus vulgaris77.781e-162 471
LLPS-Via-1559Vigna angularis77.175e-159 460
LLPS-Vir-0253Vigna radiata76.853e-158 459
LLPS-Dac-0574Daucus carota76.691e-167 482
LLPS-Coc-0887Corchorus capsularis76.456e-175 501
LLPS-Cus-0962Cucumis sativus75.621e-172 500
LLPS-Brr-2992Brassica rapa75.533e-161 466
LLPS-Bro-0709Brassica oleracea75.233e-161 466
LLPS-Thc-2221Theobroma cacao74.866e-174 499
LLPS-Brn-3315Brassica napus74.852e-159 461
LLPS-Arl-0595Arabidopsis lyrata74.622e-163 471
LLPS-Art-2069Arabidopsis thaliana74.624e-163 471
LLPS-Php-2055Physcomitrella patens74.152e-134 397
LLPS-Glm-1530Glycine max72.556e-166 479
LLPS-Gor-0719Gossypium raimondii72.252e-171 493
LLPS-Amt-1176Amborella trichopoda72.161e-164 475
LLPS-Pot-2062Populus trichocarpa72.161e-172 496
LLPS-Prp-0666Prunus persica72.136e-166 479
LLPS-Nia-1929Nicotiana attenuata71.913e-167 481
LLPS-Viv-1131Vitis vinifera71.058e-169 486
LLPS-Sot-1591Solanum tuberosum70.84e-166 479
LLPS-Hea-1043Helianthus annuus70.721e-160 465
LLPS-Met-0172Medicago truncatula70.369e-165 475
LLPS-Mae-2434Manihot esculenta69.921e-170 491
LLPS-Sem-0790Selaginella moellendorffii67.633e-121 360
LLPS-Ran-3592Rattus norvegicus66.523e-105 322
LLPS-Mea-1141Mesocricetus auratus66.521e-105 323
LLPS-Mal-3944Mandrillus leucophaeus66.372e-106 325
LLPS-Cap-0553Cavia porcellus66.364e-105 322
LLPS-Ora-2996Ornithorhynchus anatinus66.082e-76 243
LLPS-Cas-3472Carlito syrichta65.475e-105 322
LLPS-Mod-4065Monodelphis domestica65.455e-103 317
LLPS-Gaga-3337Gallus gallus65.162e-104 320
LLPS-Dio-0867Dipodomys ordii65.027e-105 322
LLPS-Pes-0301Pelodiscus sinensis64.631e-100 305
LLPS-Fud-3127Fukomys damarensis64.382e-105 323
LLPS-Mum-3198Mus musculus64.358e-106 324
LLPS-Sah-0751Sarcophilus harrisii64.023e-80 258
LLPS-Lac-0879Latimeria chalumnae63.321e-98 300
LLPS-Tut-2284Tursiops truncatus63.044e-102 314
LLPS-Anc-1234Anolis carolinensis62.741e-101 312
LLPS-Chr-0278Chlamydomonas reinhardtii62.722e-120 360
LLPS-Mel-1243Melampsora laricipopulina62.674e-116 347
LLPS-Cii-1214Ciona intestinalis61.262e-108 328
LLPS-Orn-1406Oreochromis niloticus60.282e-112 342
LLPS-Dar-3579Danio rerio60.286e-112 341
LLPS-Tar-2050Takifugu rubripes59.513e-112 341
LLPS-Paa-3219Papio anubis59.367e-107 327
LLPS-Gog-3098Gorilla gorilla59.361e-106 327
LLPS-Chs-2359Chlorocebus sabaeus59.369e-107 327
LLPS-Mam-3399Macaca mulatta59.368e-107 327
LLPS-Hos-4582Homo sapiens59.361e-106 327
LLPS-Aim-4349Ailuropoda melanoleuca59.011e-106 327
LLPS-Myl-4060Myotis lucifugus59.016e-107 327
LLPS-Urm-3117Ursus maritimus59.011e-105 325
LLPS-Abg-1124Absidia glauca58.789e-116 349
LLPS-Crn-1576Cryptococcus neoformans58.422e-116 352
LLPS-Gaa-0297Gasterosteus aculeatus58.283e-111 338
LLPS-Nol-3325Nomascus leucogenys58.283e-107 327
LLPS-Pat-1720Pan troglodytes58.281e-106 327
LLPS-Pap-1092Pan paniscus58.281e-106 327
LLPS-Ten-2914Tetraodon nigroviridis58.254e-109 333
LLPS-Caf-0427Canis familiaris58.113e-106 326
LLPS-Fia-3588Ficedula albicollis58.094e-100 308
LLPS-Asm-0835Astyanax mexicanus58.051e-113 345
LLPS-Sus-2510Sus scrofa57.937e-108 329
LLPS-Poa-0343Pongo abelii57.931e-107 327
LLPS-Scj-0940Schizosaccharomyces japonicus57.873e-92 289
LLPS-Pug-0446Puccinia graminis57.866e-112 340
LLPS-Caj-3013Callithrix jacchus57.772e-105 324
LLPS-Otg-0447Otolemur garnettii57.772e-107 328
LLPS-Pof-2963Poecilia formosa57.771e-113 345
LLPS-Scf-2537Scleropages formosus57.652e-113 345
LLPS-Aon-3183Aotus nancymaae57.591e-105 324
LLPS-Xim-2923Xiphophorus maculatus57.432e-112 343
LLPS-Tum-1311Tuber melanosporum57.367e-102 314
LLPS-Miv-0143Microbotryum violaceum57.342e-107 329
LLPS-Ict-1869Ictidomys tridecemlineatus57.282e-105 323
LLPS-Ova-0513Ovis aries57.095e-105 322
LLPS-Bot-2389Bos taurus57.092e-105 323
LLPS-Chc-0724Chondrus crispus56.926e-66 218
LLPS-Fec-4423Felis catus56.841e-96 300
LLPS-Tag-0549Taeniopygia guttata56.588e-111 336
LLPS-Loa-3800Loxodonta africana56.441e-105 323
LLPS-Asg-1431Ashbya gossypii56.253e-103 318
LLPS-Leo-0187Lepisosteus oculatus56.014e-113 343
LLPS-Cea-4639Cercocebus atys55.96e-93 291
LLPS-Maf-2466Macaca fascicularis55.97e-93 291
LLPS-Rhb-3799Rhinopithecus bieti55.97e-93 291
LLPS-Man-0465Macaca nemestrina55.97e-93 291
LLPS-Osl-0405Ostreococcus lucimarinus55.718e-83 260
LLPS-Eqc-0451Equus caballus55.481e-106 326
LLPS-Kop-1217Komagataella pastoris55.295e-106 325
LLPS-Scm-1829Scophthalmus maximus54.46e-111 338
LLPS-Fus-0713Fusarium solani54.091e-97 303
LLPS-Cis-1219Ciona savignyi53.511e-105 321
LLPS-Cog-1451Colletotrichum gloeosporioides53.243e-93 293
LLPS-Trv-0585Trichoderma virens53.035e-86 273
LLPS-Cae-0197Caenorhabditis elegans53.02e-92 289
LLPS-Coo-1618Colletotrichum orbiculare52.862e-93 293
LLPS-Ved-1137Verticillium dahliae52.716e-93 291
LLPS-Gag-0751Gaeumannomyces graminis52.693e-94 295
LLPS-Icp-0053Ictalurus punctatus52.663e-115 349
LLPS-Mao-0205Magnaporthe oryzae52.55e-93 292
LLPS-Scc-1327Schizosaccharomyces cryophilus52.363e-94 294
LLPS-Fuv-1452Fusarium verticillioides52.296e-98 304
LLPS-Fuo-1468Fusarium oxysporum51.963e-97 303
LLPS-Yal-0365Yarrowia lipolytica51.546e-91 287
LLPS-Beb-0050Beauveria bassiana51.497e-92 288
LLPS-Zyt-0200Zymoseptoria tritici51.451e-86 274
LLPS-Map-1116Magnaporthe poae51.431e-93 293
LLPS-Scp-1585Schizosaccharomyces pombe51.334e-103 317
LLPS-Blg-1199Blumeria graminis51.312e-96 300
LLPS-Drm-1470Drosophila melanogaster51.121e-78 254
LLPS-Gas-1304Galdieria sulphuraria51.013e-88 278
LLPS-Nec-0341Neurospora crassa50.894e-90 285
LLPS-Asn-1192Aspergillus nidulans50.814e-96 300
LLPS-Asfu-1106Aspergillus fumigatus50.656e-98 305
LLPS-Nef-0187Neosartorya fischeri50.657e-98 305
LLPS-Trr-1606Trichoderma reesei50.653e-91 287
LLPS-Asc-0725Aspergillus clavatus50.325e-96 300
LLPS-Spr-1221Sporisorium reilianum49.71e-97 305
LLPS-Asf-0955Aspergillus flavus49.685e-96 300
LLPS-Aso-0123Aspergillus oryzae49.685e-96 300
LLPS-Ast-1343Aspergillus terreus49.661e-89 283
LLPS-Mup-1623Mustela putorius furo49.45e-86 274
LLPS-Sac-1529Saccharomyces cerevisiae49.351e-98 306
LLPS-Asni-0732Aspergillus niger49.354e-97 302
LLPS-Dos-1063Dothistroma septosporum49.345e-89 281
LLPS-Cogr-0651Colletotrichum graminicola48.464e-94 295
LLPS-Usm-0606Ustilago maydis47.861e-95 300
LLPS-Phn-0623Phaeosphaeria nodorum47.81e-87 279
LLPS-Pytr-0441Pyrenophora triticirepentis46.594e-91 288
LLPS-Lem-1450Leptosphaeria maculans46.492e-86 276
LLPS-Cym-0035Cyanidioschyzon merolae46.211e-70 235
LLPS-Pyt-1126Pyrenophora teres45.994e-90 286
LLPS-Orc-3841Oryctolagus cuniculus45.531e-61 210
LLPS-Put-1219Puccinia triticina41.062e-63 214