LLPS-Scp-1585
SPBC119.15
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | GPN-loop GTPase 1 |
| Gene Name: | SPBC119.15 |
| Ensembl Gene: | SPBC119.15 |
| Ensembl Protein: | SPBC119.15.1 |
| Organism: | Schizosaccharomyces pombe |
| Taxa ID: | 284812 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| P-body | Predicted from orthologs | (View) |
▼ FUNCTION
| Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | SPBC119.15.1 | SPBC119.15.1 |
| UniProt | O42906, GPN1_SCHPO | |
| GeneBank | CU329671 | CAA17930.1 |
| RefSeq | NM_001021204.2 | NP_595297.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTDKEKKPCA IIVVGMAGSG KTTFMQQLNA HLHSKNKPPY ILNLDPAVRN LPYEANIDIR 60 61 DTINYKEVMK QYNLGPNGGI MTSLNLFVTK FDQVLKILEK RAPTVDHILI DTPGQIEIFQ 120 121 WSASGSIICD TLASSWPTCI AYVVDTPRAT STSTWMSSML YACSMLYKAK LPLIIVYNKC 180 181 DVQDSEFAKK WMTDFEEFQQ AVTKDEGMSS EGATSGYMGS LVNSMSLMLE EFYRHLDFVS 240 241 CSSVTGEGMD DFLEAVKAKV KEYEEEYVPE MERMKEIQRQ TKERQKEAQL SKLMKDMHVS 300 301 KDKEDVGLTV SDAEDEYNGE LVDPDEDDGL TAEDREDMIK QYRVALGISD DISDEKLLEM 360 361 LTERMKQ 367 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACAGATA AAGAGAAGAA GCCTTGTGCC ATCATAGTTG TAGGAATGGC CGGTTCAGGC 60 61 AAAACCACCT TCATGCAACA ACTGAATGCA CACCTTCATT CAAAAAATAA ACCTCCTTAC 120 121 ATTTTAAACT TGGATCCTGC TGTTCGAAAT TTACCCTATG AGGCAAATAT CGATATTCGT 180 181 GATACAATCA ATTATAAAGA GGTTATGAAA CAATATAACT TGGGGCCAAA TGGCGGTATT 240 241 ATGACAAGTT TAAACTTATT TGTTACAAAG TTTGATCAAG TACTAAAAAT TTTGGAAAAA 300 301 CGTGCACCAA CAGTCGATCA CATTTTGATA GATACTCCTG GACAAATAGA AATTTTTCAA 360 361 TGGTCTGCCT CTGGAAGTAT CATATGCGAT ACACTTGCCA GTTCTTGGCC AACATGCATC 420 421 GCTTATGTTG TCGATACGCC AAGGGCAACA TCTACTTCAA CATGGATGTC ATCTATGCTT 480 481 TATGCATGCT CTATGCTCTA TAAAGCCAAG CTCCCACTTA TCATTGTTTA TAATAAATGT 540 541 GATGTTCAAG ATAGCGAATT TGCGAAGAAA TGGATGACCG ATTTTGAAGA GTTCCAGCAA 600 601 GCTGTGACTA AAGACGAAGG TATGAGTTCT GAGGGTGCGA CATCTGGATA TATGGGTTCG 660 661 TTGGTAAACA GTATGTCTTT AATGCTTGAG GAATTTTATC GTCATTTAGA TTTCGTGTCC 720 721 TGTTCGTCTG TGACAGGTGA AGGCATGGAT GATTTTTTAG AAGCTGTTAA AGCTAAAGTT 780 781 AAGGAGTACG AGGAAGAATA TGTTCCAGAA ATGGAACGAA TGAAAGAAAT TCAACGACAG 840 841 ACGAAAGAGA GACAAAAAGA AGCTCAGCTT TCTAAACTCA TGAAAGACAT GCATGTTTCT 900 901 AAAGATAAAG AGGATGTTGG TCTAACTGTT TCGGATGCCG AAGATGAATA TAATGGCGAG 960 961 TTAGTGGATC CTGACGAAGA TGATGGTTTA ACTGCTGAAG ATAGAGAAGA TATGATTAAG 1020 1021 CAATATCGTG TTGCTCTTGG TATCTCTGAC GATATCTCTG ATGAAAAGCT TCTTGAAATG 1080 1081 CTTACAGAGC GTATGAAGCA ATAA 1104 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Molecular Function | ATPase activity | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Biological Process | RNA polymerase II core complex assembly |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Scc-1327 | Schizosaccharomyces cryophilus | 79.62 | 0.0 | 533 |
| LLPS-Scj-0940 | Schizosaccharomyces japonicus | 77.56 | 4e-178 | 506 |
| LLPS-Tum-1311 | Tuber melanosporum | 65.6 | 2e-126 | 375 |
| LLPS-Pug-0446 | Puccinia graminis | 65.2 | 6e-119 | 357 |
| LLPS-Sah-0751 | Sarcophilus harrisii | 64.91 | 2e-77 | 249 |
| LLPS-Asfu-1106 | Aspergillus fumigatus | 64.63 | 3e-134 | 396 |
| LLPS-Nef-0187 | Neosartorya fischeri | 63.67 | 2e-133 | 395 |
| LLPS-Asni-0732 | Aspergillus niger | 63.58 | 1e-130 | 387 |
| LLPS-Trr-1606 | Trichoderma reesei | 63.49 | 1e-110 | 336 |
| LLPS-Ast-1343 | Aspergillus terreus | 63.46 | 2e-119 | 358 |
| LLPS-Abg-1124 | Absidia glauca | 63.21 | 6e-129 | 382 |
| LLPS-Asf-0955 | Aspergillus flavus | 62.94 | 6e-125 | 373 |
| LLPS-Aso-0123 | Aspergillus oryzae | 62.94 | 6e-125 | 373 |
| LLPS-Crn-1576 | Cryptococcus neoformans | 62.84 | 8e-122 | 365 |
| LLPS-Trv-0585 | Trichoderma virens | 62.45 | 6e-105 | 320 |
| LLPS-Zyt-0200 | Zymoseptoria tritici | 61.51 | 4e-114 | 343 |
| LLPS-Mel-1243 | Melampsora laricipopulina | 61.49 | 2e-123 | 365 |
| LLPS-Bro-0709 | Brassica oleracea | 61.04 | 1e-109 | 333 |
| LLPS-Brr-2992 | Brassica rapa | 61.04 | 8e-110 | 333 |
| LLPS-Brn-3315 | Brassica napus | 60.64 | 7e-109 | 331 |
| LLPS-Gag-0751 | Gaeumannomyces graminis | 59.87 | 2e-125 | 374 |
| LLPS-Hea-1043 | Helianthus annuus | 59.84 | 9e-106 | 323 |
| LLPS-Fus-0713 | Fusarium solani | 59.74 | 2e-118 | 355 |
| LLPS-Map-1116 | Magnaporthe poae | 59.68 | 1e-125 | 374 |
| LLPS-Cis-1219 | Ciona savignyi | 59.35 | 8e-107 | 323 |
| LLPS-Cus-0962 | Cucumis sativus | 59.13 | 1e-105 | 327 |
| LLPS-Nia-1929 | Nicotiana attenuata | 59.04 | 5e-106 | 324 |
| LLPS-Mao-0205 | Magnaporthe oryzae | 58.97 | 4e-123 | 368 |
| LLPS-Eqc-0451 | Equus caballus | 58.87 | 4e-97 | 300 |
| LLPS-Met-0172 | Medicago truncatula | 58.63 | 4e-105 | 322 |
| LLPS-Pes-0301 | Pelodiscus sinensis | 58.33 | 7e-96 | 292 |
| LLPS-Mae-2434 | Manihot esculenta | 58.23 | 2e-106 | 325 |
| LLPS-Cogr-0651 | Colletotrichum graminicola | 58.18 | 6e-122 | 365 |
| LLPS-Asn-1192 | Aspergillus nidulans | 58.11 | 2e-128 | 382 |
| LLPS-Fuv-1452 | Fusarium verticillioides | 58.02 | 5e-120 | 360 |
| LLPS-Ved-1137 | Verticillium dahliae | 57.88 | 3e-115 | 347 |
| LLPS-Cii-1214 | Ciona intestinalis | 57.87 | 1e-106 | 323 |
| LLPS-Fuo-1468 | Fusarium oxysporum | 57.72 | 8e-119 | 357 |
| LLPS-Dos-1063 | Dothistroma septosporum | 57.59 | 5e-118 | 355 |
| LLPS-Asg-1431 | Ashbya gossypii | 57.58 | 4e-124 | 370 |
| LLPS-Asc-0725 | Aspergillus clavatus | 57.41 | 1e-131 | 390 |
| LLPS-Scm-1829 | Scophthalmus maximus | 57.09 | 8e-102 | 313 |
| LLPS-Kop-1217 | Komagataella pastoris | 56.9 | 2e-130 | 386 |
| LLPS-Mal-3944 | Mandrillus leucophaeus | 56.85 | 3e-101 | 310 |
| LLPS-Lac-0879 | Latimeria chalumnae | 56.58 | 5e-92 | 282 |
| LLPS-Miv-0143 | Microbotryum violaceum | 56.44 | 3e-117 | 353 |
| LLPS-Chr-0278 | Chlamydomonas reinhardtii | 56.05 | 2e-99 | 306 |
| LLPS-Cae-0197 | Caenorhabditis elegans | 56.05 | 1e-96 | 298 |
| LLPS-Coo-1618 | Colletotrichum orbiculare | 56.01 | 2e-119 | 358 |
| LLPS-Tag-0549 | Taeniopygia guttata | 55.86 | 1e-106 | 324 |
| LLPS-Gaga-3337 | Gallus gallus | 55.86 | 1e-105 | 322 |
| LLPS-Asm-0835 | Astyanax mexicanus | 55.82 | 1e-105 | 323 |
| LLPS-Gaa-0297 | Gasterosteus aculeatus | 55.74 | 4e-107 | 326 |
| LLPS-Mua-2545 | Musa acuminata | 55.68 | 1e-71 | 231 |
| LLPS-Dar-3579 | Danio rerio | 55.63 | 4e-106 | 324 |
| LLPS-Zem-2576 | Zea mays | 55.56 | 8e-101 | 311 |
| LLPS-Cog-1451 | Colletotrichum gloeosporioides | 55.56 | 1e-118 | 357 |
| LLPS-Mea-1141 | Mesocricetus auratus | 55.52 | 3e-103 | 316 |
| LLPS-Sus-2510 | Sus scrofa | 55.48 | 4e-106 | 323 |
| LLPS-Nec-0341 | Neurospora crassa | 55.38 | 6e-123 | 367 |
| LLPS-Icp-0053 | Ictalurus punctatus | 55.25 | 1e-105 | 323 |
| LLPS-Fia-3588 | Ficedula albicollis | 55.22 | 4e-94 | 291 |
| LLPS-Ran-3592 | Rattus norvegicus | 55.17 | 2e-102 | 314 |
| LLPS-Sob-1470 | Sorghum bicolor | 55.16 | 4e-100 | 309 |
| LLPS-Prp-0666 | Prunus persica | 55.07 | 1e-108 | 331 |
| LLPS-Amt-1176 | Amborella trichopoda | 55.02 | 2e-99 | 307 |
| LLPS-Ors-1533 | Oryza sativa | 54.82 | 7e-105 | 321 |
| LLPS-Orgl-2217 | Oryza glumaepatula | 54.82 | 7e-105 | 321 |
| LLPS-Orni-2281 | Oryza nivara | 54.82 | 7e-105 | 321 |
| LLPS-Myl-4060 | Myotis lucifugus | 54.79 | 2e-103 | 317 |
| LLPS-Ova-0513 | Ovis aries | 54.79 | 6e-103 | 316 |
| LLPS-Sot-1591 | Solanum tuberosum | 54.76 | 1e-106 | 325 |
| LLPS-Leo-0187 | Lepisosteus oculatus | 54.76 | 5e-104 | 319 |
| LLPS-Sac-1529 | Saccharomyces cerevisiae | 54.68 | 2e-119 | 358 |
| LLPS-Mum-3198 | Mus musculus | 54.67 | 3e-103 | 316 |
| LLPS-Tar-2050 | Takifugu rubripes | 54.64 | 2e-104 | 320 |
| LLPS-Dac-0574 | Daucus carota | 54.52 | 8e-106 | 323 |
| LLPS-Orr-1432 | Oryza rufipogon | 54.49 | 5e-104 | 319 |
| LLPS-Orbr-0878 | Oryza brachyantha | 54.49 | 2e-101 | 312 |
| LLPS-Ori-2350 | Oryza indica | 54.46 | 3e-105 | 322 |
| LLPS-Nol-3325 | Nomascus leucogenys | 54.45 | 5e-103 | 315 |
| LLPS-Mam-3399 | Macaca mulatta | 54.45 | 9e-103 | 315 |
| LLPS-Poa-0343 | Pongo abelii | 54.45 | 7e-104 | 317 |
| LLPS-Loa-3800 | Loxodonta africana | 54.45 | 2e-102 | 314 |
| LLPS-Pap-1092 | Pan paniscus | 54.45 | 1e-102 | 315 |
| LLPS-Pat-1720 | Pan troglodytes | 54.45 | 1e-102 | 315 |
| LLPS-Hos-4582 | Homo sapiens | 54.45 | 8e-103 | 315 |
| LLPS-Paa-3219 | Papio anubis | 54.45 | 8e-103 | 315 |
| LLPS-Bot-2389 | Bos taurus | 54.45 | 2e-102 | 314 |
| LLPS-Gog-3098 | Gorilla gorilla | 54.45 | 7e-103 | 316 |
| LLPS-Chs-2359 | Chlorocebus sabaeus | 54.45 | 8e-103 | 315 |
| LLPS-Pot-2062 | Populus trichocarpa | 54.39 | 3e-108 | 330 |
| LLPS-Anc-1234 | Anolis carolinensis | 54.38 | 2e-92 | 287 |
| LLPS-Scf-2537 | Scleropages formosus | 54.27 | 2e-105 | 323 |
| LLPS-Blg-1199 | Blumeria graminis | 54.13 | 8e-130 | 384 |
| LLPS-Cas-3472 | Carlito syrichta | 54.11 | 7e-102 | 313 |
| LLPS-Ten-2914 | Tetraodon nigroviridis | 54.11 | 4e-102 | 313 |
| LLPS-Fud-3127 | Fukomys damarensis | 54.11 | 2e-101 | 311 |
| LLPS-Ora-2996 | Ornithorhynchus anatinus | 54.08 | 6e-65 | 212 |
| LLPS-Beb-0050 | Beauveria bassiana | 54.06 | 2e-116 | 350 |
| LLPS-Mod-4065 | Monodelphis domestica | 54.01 | 5e-99 | 305 |
| LLPS-Art-2069 | Arabidopsis thaliana | 53.87 | 3e-107 | 327 |
| LLPS-Arl-0595 | Arabidopsis lyrata | 53.87 | 4e-107 | 326 |
| LLPS-Dio-0867 | Dipodomys ordii | 53.77 | 3e-100 | 308 |
| LLPS-Phv-2003 | Phaseolus vulgaris | 53.72 | 6e-105 | 322 |
| LLPS-Yal-0365 | Yarrowia lipolytica | 53.63 | 3e-119 | 358 |
| LLPS-Ict-1869 | Ictidomys tridecemlineatus | 53.61 | 4e-103 | 316 |
| LLPS-Glm-1530 | Glycine max | 53.56 | 8e-105 | 321 |
| LLPS-Sei-0611 | Setaria italica | 53.49 | 2e-101 | 312 |
| LLPS-Fec-4423 | Felis catus | 53.45 | 1e-91 | 286 |
| LLPS-Xim-2923 | Xiphophorus maculatus | 53.45 | 4e-101 | 313 |
| LLPS-Tut-2284 | Tursiops truncatus | 53.42 | 2e-99 | 306 |
| LLPS-Pof-2963 | Poecilia formosa | 53.1 | 3e-102 | 314 |
| LLPS-Via-1559 | Vigna angularis | 53.04 | 3e-105 | 322 |
| LLPS-Php-2055 | Physcomitrella patens | 52.98 | 4e-98 | 303 |
| LLPS-Caf-0427 | Canis familiaris | 52.9 | 1e-102 | 315 |
| LLPS-Hov-1136 | Hordeum vulgare | 52.82 | 4e-99 | 306 |
| LLPS-Vir-0253 | Vigna radiata | 52.7 | 3e-105 | 322 |
| LLPS-Tra-0963 | Triticum aestivum | 52.67 | 3e-103 | 318 |
| LLPS-Tru-1417 | Triticum urartu | 52.48 | 2e-99 | 308 |
| LLPS-Brd-1310 | Brachypodium distachyon | 52.48 | 1e-99 | 308 |
| LLPS-Gor-0719 | Gossypium raimondii | 52.35 | 1e-104 | 320 |
| LLPS-Viv-1131 | Vitis vinifera | 52.03 | 2e-103 | 318 |
| LLPS-Urm-3117 | Ursus maritimus | 52.02 | 5e-104 | 320 |
| LLPS-Aim-4349 | Ailuropoda melanoleuca | 52.02 | 7e-105 | 321 |
| LLPS-Coc-0887 | Corchorus capsularis | 52.0 | 5e-107 | 327 |
| LLPS-Thc-2221 | Theobroma cacao | 51.85 | 8e-107 | 327 |
| LLPS-Otg-0447 | Otolemur garnettii | 51.71 | 2e-104 | 319 |
| LLPS-Gas-1304 | Galdieria sulphuraria | 51.44 | 1e-89 | 280 |
| LLPS-Chc-0724 | Chondrus crispus | 51.38 | 2e-60 | 203 |
| LLPS-Lem-1450 | Leptosphaeria maculans | 51.25 | 3e-114 | 347 |
| LLPS-Cap-0553 | Cavia porcellus | 50.58 | 2e-103 | 317 |
| LLPS-Pyt-1126 | Pyrenophora teres | 50.38 | 1e-118 | 358 |
| LLPS-Rhb-3799 | Rhinopithecus bieti | 50.17 | 7e-88 | 277 |
| LLPS-Man-0465 | Macaca nemestrina | 50.17 | 7e-88 | 277 |
| LLPS-Cea-4639 | Cercocebus atys | 50.17 | 6e-88 | 277 |
| LLPS-Maf-2466 | Macaca fascicularis | 50.17 | 7e-88 | 277 |
| LLPS-Orn-1406 | Oreochromis niloticus | 50.14 | 3e-105 | 322 |
| LLPS-Pytr-0441 | Pyrenophora triticirepentis | 50.13 | 9e-120 | 360 |
| LLPS-Sem-0790 | Selaginella moellendorffii | 49.83 | 9e-93 | 286 |
| LLPS-Usm-0606 | Ustilago maydis | 49.48 | 8e-113 | 343 |
| LLPS-Spr-1221 | Sporisorium reilianum | 49.47 | 2e-113 | 344 |
| LLPS-Orm-0227 | Oryza meridionalis | 49.4 | 1e-98 | 305 |
| LLPS-Caj-3013 | Callithrix jacchus | 49.38 | 4e-102 | 314 |
| LLPS-Orp-1220 | Oryza punctata | 49.05 | 8e-55 | 187 |
| LLPS-Lep-0753 | Leersia perrieri | 48.8 | 2e-54 | 186 |
| LLPS-Aon-3183 | Aotus nancymaae | 48.76 | 5e-101 | 311 |
| LLPS-Phn-0623 | Phaeosphaeria nodorum | 48.38 | 8e-112 | 340 |
| LLPS-Drm-1470 | Drosophila melanogaster | 47.6 | 4e-74 | 241 |
| LLPS-Mup-1623 | Mustela putorius furo | 47.22 | 7e-85 | 270 |
| LLPS-Osl-0405 | Ostreococcus lucimarinus | 46.64 | 7e-78 | 246 |
| LLPS-Put-1219 | Puccinia triticina | 45.43 | 3e-72 | 235 |
| LLPS-Orc-3841 | Oryctolagus cuniculus | 45.1 | 6e-66 | 220 |
| LLPS-Orb-1726 | Oryza barthii | 44.9 | 8e-23 | 99.0 |
| LLPS-Cym-0035 | Cyanidioschyzon merolae | 42.65 | 1e-66 | 223 |