LLPS-Scp-1279
gcd10
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6; General control non-derepressible protein 10; Protein gcd10; tRNA(m1A58)-methyltransferase subunit trm6; tRNA(m1A58)MTase subunit trm6 |
| Gene Name: | gcd10, trm6, SPBC800.08 |
| Ensembl Gene: | SPBC800.08 |
| Ensembl Protein: | SPBC800.08.1 |
| Organism: | Schizosaccharomyces pombe |
| Taxa ID: | 284812 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | SPBC800.08.1 | SPBC800.08.1 |
| UniProt | Q9HGL4, TRM6_SCHPO | |
| GeneBank | CU329671 | CAC01523.1 |
| RefSeq | NM_001021016.2 | NP_595109.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MLRHASTISE NSSVFIKLPS DNVRFVTLKP NNTIHLGKFG SFLADDLFGK HFDETFEIYQ 60 61 PKKIRVLKTR EVQYIEEEKK TNQELNDCRG NQLMTQEEID ELRANIKAGG LRAEEAIKQL 120 121 TNSSKTFEQK TLFAQEKYVT RKGEKYLQRF QVLRPCVEVV ANYMIEHDPY KILDLTAECI 180 181 SLMLTLGNVK PGGRYLVVDE TGCMFLGSLI DRVAGDCKIT LVHPNEQPNS SCLEYWGQDF 240 241 KEDSLVQKGI LKTLNWYQVT NPTETLSEYS VEDIPESELN EMKLRHRKRY ETKKATFNRL 300 301 KNTIDDFESG NYDALFILSI HTPMSVLQHL LPKLGISRPF MVYSTYQQVL VETYHQLSKW 360 361 DNLFVEKTAQ STENDEKVDQ GDVAIDTQKE KVIMLDIHEI RTRPYQVLPE RTHPFMTVRG 420 421 DMGFVLSGIK VLTSDSNLAA GRFPKRKGQK ETSSVKKAKL EN 462 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCTGAGGC ATGCATCAAC TATTTCCGAA AACAGCAGCG TTTTCATCAA GCTTCCTTCA 60 61 GACAATGTTC GTTTTGTAAC ATTGAAACCA AACAATACAA TTCACCTCGG AAAATTTGGT 120 121 TCATTTCTCG CTGATGATTT GTTTGGAAAG CATTTTGACG AAACTTTTGA AATTTATCAA 180 181 CCCAAAAAAA TTCGAGTTTT AAAAACAAGG GAGGTACAGT ATATCGAGGA AGAAAAGAAA 240 241 ACGAATCAAG AACTTAATGA TTGTCGAGGC AATCAGCTTA TGACTCAAGA GGAGATTGAT 300 301 GAACTGCGCG CAAACATTAA AGCTGGTGGA CTTCGTGCTG AAGAGGCCAT CAAACAGTTG 360 361 ACTAATAGTA GTAAAACTTT TGAGCAAAAA ACTTTATTTG CTCAGGAGAA ATATGTTACG 420 421 AGAAAAGGGG AAAAGTATCT TCAACGCTTT CAGGTTTTAC GACCTTGTGT TGAAGTTGTG 480 481 GCTAATTACA TGATTGAACA TGATCCGTAT AAGATACTTG ATCTTACTGC CGAGTGTATA 540 541 AGCTTGATGC TTACTCTTGG AAATGTTAAA CCTGGGGGTA GATATTTGGT AGTTGATGAG 600 601 ACTGGATGCA TGTTCCTTGG TTCTCTTATT GACCGTGTTG CTGGTGATTG CAAAATAACC 660 661 CTGGTCCATC CAAATGAGCA ACCTAATAGC TCTTGTTTAG AGTATTGGGG GCAAGACTTT 720 721 AAAGAGGATA GTTTGGTTCA AAAAGGGATT TTGAAAACTT TGAATTGGTA TCAAGTTACG 780 781 AATCCAACCG AGACTTTAAG TGAGTATTCG GTTGAAGATA TTCCTGAATC AGAGTTGAAT 840 841 GAGATGAAAC TTCGCCACCG TAAGCGCTAT GAAACGAAGA AAGCTACATT TAACCGTTTG 900 901 AAGAATACTA TTGATGATTT TGAAAGTGGT AACTATGATG CTCTCTTTAT ACTATCTATT 960 961 CACACCCCAA TGTCTGTTCT TCAACATCTT CTTCCAAAGC TCGGTATATC ACGTCCTTTC 1020 1021 ATGGTATACT CAACATATCA GCAAGTCTTA GTCGAGACGT ATCATCAATT ATCTAAATGG 1080 1081 GATAACTTAT TTGTAGAAAA GACAGCTCAA AGTACTGAAA ATGACGAAAA GGTTGATCAA 1140 1141 GGAGACGTTG CTATTGATAC ACAGAAAGAG AAAGTCATCA TGCTGGATAT TCATGAGATT 1200 1201 CGTACACGAC CTTACCAAGT CTTGCCAGAA AGGACTCATC CATTCATGAC TGTTAGGGGT 1260 1261 GATATGGGTT TCGTTTTATC TGGGATCAAG GTGTTAACTT CTGACAGCAA TCTAGCTGCC 1320 1321 GGAAGGTTTC CAAAACGTAA GGGCCAGAAA GAAACTTCTT CTGTCAAAAA AGCAAAATTG 1380 1381 GAAAATTAG 1389 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleus | |
Cellular Component | TRNA (m1A) methyltransferase complex | |
Molecular Function | TRNA binding | |
Biological Process | TRNA methylation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Scc-1434 | Schizosaccharomyces cryophilus | 67.03 | 0.0 | 659 |
| LLPS-Scj-0575 | Schizosaccharomyces japonicus | 51.4 | 4e-168 | 489 |
| LLPS-Tru-0551 | Triticum urartu | 35.14 | 5e-07 | 55.8 |
| LLPS-Hov-0756 | Hordeum vulgare | 34.15 | 2e-07 | 57.4 |
| LLPS-Orbr-0711 | Oryza brachyantha | 33.62 | 1e-06 | 54.7 |
| LLPS-Yal-0734 | Yarrowia lipolytica | 32.76 | 3e-67 | 229 |
| LLPS-Fud-1468 | Fukomys damarensis | 30.73 | 7e-16 | 84.0 |
| LLPS-Ora-3201 | Ornithorhynchus anatinus | 30.69 | 3e-16 | 85.1 |
| LLPS-Tum-1342 | Tuber melanosporum | 30.66 | 2e-58 | 207 |
| LLPS-Usm-0089 | Ustilago maydis | 30.56 | 7e-59 | 209 |
| LLPS-Abg-1059 | Absidia glauca | 30.37 | 1e-51 | 187 |
| LLPS-Poa-3587 | Pongo abelii | 30.35 | 2e-16 | 85.9 |
| LLPS-Nol-0681 | Nomascus leucogenys | 30.35 | 1e-16 | 86.3 |
| LLPS-Rhb-1995 | Rhinopithecus bieti | 30.35 | 1e-16 | 86.3 |
| LLPS-Aim-0310 | Ailuropoda melanoleuca | 30.35 | 4e-16 | 84.7 |
| LLPS-Paa-2839 | Papio anubis | 30.35 | 2e-16 | 85.9 |
| LLPS-Mal-0202 | Mandrillus leucophaeus | 30.35 | 2e-16 | 85.9 |
| LLPS-Cea-0322 | Cercocebus atys | 30.35 | 2e-16 | 85.9 |
| LLPS-Chs-2093 | Chlorocebus sabaeus | 30.35 | 2e-16 | 85.9 |
| LLPS-Dio-2468 | Dipodomys ordii | 30.21 | 6e-16 | 84.0 |
| LLPS-Chr-0819 | Chlamydomonas reinhardtii | 30.09 | 5e-15 | 81.6 |
| LLPS-Spr-1260 | Sporisorium reilianum | 29.85 | 7e-55 | 197 |
| LLPS-Cap-0468 | Cavia porcellus | 29.85 | 8e-16 | 83.6 |
| LLPS-Cas-2662 | Carlito syrichta | 29.85 | 2e-16 | 85.5 |
| LLPS-Fec-2888 | Felis catus | 29.85 | 5e-16 | 84.3 |
| LLPS-Pat-1021 | Pan troglodytes | 29.85 | 8e-16 | 83.6 |
| LLPS-Hos-0875 | Homo sapiens | 29.85 | 5e-16 | 84.3 |
| LLPS-Otg-0949 | Otolemur garnettii | 29.85 | 2e-15 | 82.8 |
| LLPS-Mup-1518 | Mustela putorius furo | 29.85 | 9e-16 | 83.6 |
| LLPS-Sah-2951 | Sarcophilus harrisii | 29.85 | 3e-15 | 82.0 |
| LLPS-Gog-2438 | Gorilla gorilla | 29.85 | 6e-16 | 84.3 |
| LLPS-Asfu-1085 | Aspergillus fumigatus | 29.84 | 7e-59 | 209 |
| LLPS-Xet-3412 | Xenopus tropicalis | 29.79 | 1e-15 | 83.6 |
| LLPS-Kop-1104 | Komagataella pastoris | 29.65 | 3e-61 | 212 |
| LLPS-Ere-0565 | Erinaceus europaeus | 29.35 | 1e-14 | 80.5 |
| LLPS-Nef-0848 | Neosartorya fischeri | 29.34 | 4e-58 | 207 |
| LLPS-Asni-1156 | Aspergillus niger | 29.33 | 5e-48 | 177 |
| LLPS-Miv-0484 | Microbotryum violaceum | 29.26 | 2e-51 | 187 |
| LLPS-Crn-0882 | Cryptococcus neoformans | 29.12 | 1e-46 | 175 |
| LLPS-Asg-0683 | Ashbya gossypii | 28.87 | 4e-47 | 174 |
| LLPS-Anc-1014 | Anolis carolinensis | 28.86 | 3e-13 | 75.5 |
| LLPS-Orb-1565 | Oryza barthii | 28.8 | 6e-08 | 58.5 |
| LLPS-Ran-0247 | Rattus norvegicus | 28.79 | 2e-15 | 82.8 |
| LLPS-Pap-3061 | Pan paniscus | 28.71 | 4e-15 | 81.6 |
| LLPS-Amt-0796 | Amborella trichopoda | 28.7 | 9e-16 | 83.6 |
| LLPS-Asc-0043 | Aspergillus clavatus | 28.65 | 4e-54 | 196 |
| LLPS-Orr-1490 | Oryza rufipogon | 28.57 | 1e-09 | 64.7 |
| LLPS-Cii-1077 | Ciona intestinalis | 28.57 | 2e-21 | 99.8 |
| LLPS-Orni-0992 | Oryza nivara | 28.57 | 1e-09 | 64.7 |
| LLPS-Asn-1509 | Aspergillus nidulans | 28.54 | 5e-49 | 181 |
| LLPS-Asf-1332 | Aspergillus flavus | 28.49 | 2e-53 | 194 |
| LLPS-Aso-1220 | Aspergillus oryzae | 28.42 | 3e-52 | 191 |
| LLPS-Tag-1321 | Taeniopygia guttata | 28.33 | 2e-12 | 73.6 |
| LLPS-Sol-2392 | Solanum lycopersicum | 28.09 | 2e-31 | 129 |
| LLPS-Ast-0498 | Aspergillus terreus | 27.96 | 5e-52 | 190 |
| LLPS-Nia-1561 | Nicotiana attenuata | 27.96 | 5e-33 | 134 |
| LLPS-Sot-1349 | Solanum tuberosum | 27.88 | 1e-31 | 129 |
| LLPS-Sem-1621 | Selaginella moellendorffii | 27.8 | 2e-07 | 57.4 |
| LLPS-Dar-2941 | Danio rerio | 27.79 | 8e-27 | 115 |
| LLPS-Put-0022 | Puccinia triticina | 27.63 | 2e-28 | 119 |
| LLPS-Lac-0189 | Latimeria chalumnae | 27.57 | 2e-24 | 109 |
| LLPS-Pof-3202 | Poecilia formosa | 27.56 | 8e-24 | 107 |
| LLPS-Blg-1257 | Blumeria graminis | 27.56 | 4e-24 | 109 |
| LLPS-Cus-1277 | Cucumis sativus | 27.33 | 9e-31 | 127 |
| LLPS-Mum-1153 | Mus musculus | 27.27 | 2e-14 | 79.3 |
| LLPS-Icp-0335 | Ictalurus punctatus | 27.27 | 6e-26 | 113 |
| LLPS-Asm-2878 | Astyanax mexicanus | 27.23 | 3e-24 | 108 |
| LLPS-Thc-1292 | Theobroma cacao | 27.18 | 1e-30 | 127 |
| LLPS-Xim-2264 | Xiphophorus maculatus | 27.13 | 2e-24 | 109 |
| LLPS-Pug-1066 | Puccinia graminis | 27.08 | 1e-38 | 150 |
| LLPS-Scm-0988 | Scophthalmus maximus | 27.03 | 1e-25 | 112 |
| LLPS-Glm-1072 | Glycine max | 27.01 | 2e-26 | 114 |
| LLPS-Orl-0295 | Oryzias latipes | 26.99 | 6e-24 | 107 |
| LLPS-Leo-3108 | Lepisosteus oculatus | 26.81 | 7e-26 | 113 |
| LLPS-Cis-0775 | Ciona savignyi | 26.5 | 6e-22 | 101 |
| LLPS-Gaa-2317 | Gasterosteus aculeatus | 26.48 | 1e-25 | 112 |
| LLPS-Eqc-3038 | Equus caballus | 26.4 | 2e-22 | 103 |
| LLPS-Brd-1383 | Brachypodium distachyon | 26.27 | 2e-11 | 70.1 |
| LLPS-Urm-0029 | Ursus maritimus | 26.22 | 1e-19 | 95.5 |
| LLPS-Bot-1552 | Bos taurus | 26.22 | 5e-23 | 105 |
| LLPS-Brr-2754 | Brassica rapa | 26.12 | 9e-27 | 115 |
| LLPS-Scf-2449 | Scleropages formosus | 26.12 | 6e-29 | 122 |
| LLPS-Sac-0890 | Saccharomyces cerevisiae | 26.08 | 3e-39 | 152 |
| LLPS-Bro-2935 | Brassica oleracea | 26.06 | 3e-24 | 108 |
| LLPS-Orn-2256 | Oreochromis niloticus | 26.04 | 4e-22 | 102 |
| LLPS-Caf-0471 | Canis familiaris | 26.0 | 8e-23 | 104 |
| LLPS-Loa-2189 | Loxodonta africana | 25.99 | 2e-23 | 106 |
| LLPS-Mua-1280 | Musa acuminata | 25.97 | 3e-07 | 57.0 |
| LLPS-Cae-0768 | Caenorhabditis elegans | 25.96 | 4e-23 | 105 |
| LLPS-Mae-0810 | Manihot esculenta | 25.76 | 1e-30 | 126 |
| LLPS-Sus-2176 | Sus scrofa | 25.76 | 1e-22 | 105 |
| LLPS-Aon-0948 | Aotus nancymaae | 25.75 | 5e-23 | 105 |
| LLPS-Caj-3046 | Callithrix jacchus | 25.75 | 4e-23 | 105 |
| LLPS-Myl-3062 | Myotis lucifugus | 25.71 | 1e-22 | 104 |
| LLPS-Mod-0145 | Monodelphis domestica | 25.64 | 4e-19 | 94.0 |
| LLPS-Hea-2033 | Helianthus annuus | 25.64 | 3e-22 | 102 |
| LLPS-Viv-0124 | Vitis vinifera | 25.62 | 4e-23 | 105 |
| LLPS-Mam-1101 | Macaca mulatta | 25.58 | 6e-23 | 105 |
| LLPS-Man-1435 | Macaca nemestrina | 25.58 | 6e-23 | 105 |
| LLPS-Fia-0668 | Ficedula albicollis | 25.58 | 6e-20 | 95.9 |
| LLPS-Maf-4650 | Macaca fascicularis | 25.58 | 6e-23 | 105 |
| LLPS-Phv-0546 | Phaseolus vulgaris | 25.55 | 7e-27 | 116 |
| LLPS-Arl-0568 | Arabidopsis lyrata | 25.55 | 3e-22 | 102 |
| LLPS-Ova-1778 | Ovis aries | 25.52 | 1e-22 | 104 |
| LLPS-Met-1383 | Medicago truncatula | 25.42 | 4e-27 | 116 |
| LLPS-Pot-0923 | Populus trichocarpa | 25.39 | 8e-25 | 109 |
| LLPS-Art-2121 | Arabidopsis thaliana | 25.33 | 3e-21 | 99.8 |
| LLPS-Ict-0864 | Ictidomys tridecemlineatus | 25.3 | 6e-23 | 105 |
| LLPS-Brn-1921 | Brassica napus | 25.28 | 1e-26 | 115 |
| LLPS-Php-0026 | Physcomitrella patens | 25.26 | 2e-29 | 123 |
| LLPS-Tra-2467 | Triticum aestivum | 25.23 | 4e-11 | 68.9 |
| LLPS-Tar-3251 | Takifugu rubripes | 25.13 | 3e-22 | 102 |
| LLPS-Dac-0829 | Daucus carota | 25.06 | 3e-20 | 96.7 |
| LLPS-Prp-0631 | Prunus persica | 25.05 | 7e-23 | 104 |
| LLPS-Gor-0592 | Gossypium raimondii | 25.05 | 6e-27 | 116 |
| LLPS-Gaga-3587 | Gallus gallus | 24.95 | 2e-26 | 114 |
| LLPS-Mel-1020 | Melampsora laricipopulina | 24.95 | 8e-33 | 134 |
| LLPS-Meg-1921 | Meleagris gallopavo | 24.89 | 2e-21 | 100 |
| LLPS-Ors-1686 | Oryza sativa | 24.88 | 2e-10 | 67.0 |
| LLPS-Ori-0189 | Oryza indica | 24.88 | 2e-10 | 67.0 |
| LLPS-Pes-2848 | Pelodiscus sinensis | 24.87 | 2e-20 | 97.4 |
| LLPS-Osl-0733 | Ostreococcus lucimarinus | 24.83 | 3e-25 | 111 |
| LLPS-Orc-2094 | Oryctolagus cuniculus | 24.82 | 1e-20 | 98.2 |
| LLPS-Anp-0202 | Anas platyrhynchos | 24.79 | 3e-22 | 102 |
| LLPS-Sob-1835 | Sorghum bicolor | 24.46 | 2e-09 | 63.5 |
| LLPS-Sei-0051 | Setaria italica | 24.24 | 4e-10 | 65.9 |
| LLPS-Orp-0346 | Oryza punctata | 24.14 | 4e-11 | 68.9 |
| LLPS-Drm-0511 | Drosophila melanogaster | 24.09 | 9e-18 | 89.4 |
| LLPS-Lep-0458 | Leersia perrieri | 24.07 | 5e-10 | 65.9 |
| LLPS-Zem-2388 | Zea mays | 24.03 | 3e-09 | 63.2 |
| LLPS-Zyt-1367 | Zymoseptoria tritici | 24.01 | 1e-37 | 149 |
| LLPS-Via-0317 | Vigna angularis | 23.94 | 6e-25 | 110 |
| LLPS-Orm-0777 | Oryza meridionalis | 23.71 | 1e-10 | 67.4 |
| LLPS-Org-0397 | Oryza glaberrima | 23.71 | 2e-10 | 67.0 |
| LLPS-Orgl-0612 | Oryza glumaepatula | 23.71 | 2e-10 | 67.0 |
| LLPS-Mea-3248 | Mesocricetus auratus | 23.71 | 3e-22 | 103 |
| LLPS-Chc-0325 | Chondrus crispus | 23.25 | 1e-18 | 91.7 |
| LLPS-Vir-1108 | Vigna radiata | 22.6 | 4e-12 | 72.0 |