LLPS-Scp-0460
rpl502
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | 60S ribosomal protein L5-B |
| Gene Name: | rpl502, rpl5b, SPBC11C11.09c |
| Ensembl Gene: | SPBC11C11.09c |
| Ensembl Protein: | SPBC11C11.09c.1 |
| Organism: | Schizosaccharomyces pombe |
| Taxa ID: | 284812 |
| LLPS Type: | Scaffold |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Droplet, Nuclear speckle, Nucleolus, P-body, Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | SPBC11C11.09c.1 | SPBC11C11.09c.1 |
| UniProt | O74306, RL5B_SCHPO, Q76N21 | |
| GeneBank | CU329671, AB016045 | CAA20691.1, BAA31570.1 |
| RefSeq | NM_001022319.2 | NP_596399.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPFIKAVKSS PYFSRYQTKY RRRREGKTDY YARKRLIAQA KNKYNAPKYR LVVRFSNRFV 60 61 TCQIVSSRVN GDYVLAHAHS SELPRYGIKW GLANWTAAYA TGLLVARRAL AKVGLADKYE 120 121 GVTEPEGEFE LTEAIEDGPR PFKVFLDVGL KRTSTGSRVF GAMKGASDGG LFIPHSPNRF 180 181 PGFDIETEEL DDETLRKYIY GGHVAEYMEM LIDDDEERYQ KQFSGLIADG IESDQLEDIY 240 241 AEAYAKIRED PSFQKSGKDA AAFKAESLKY TQRKLTAEER KERFNAKVIE AGRA 294 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCCTTTA TCAAAGCAGT CAAGAGCAGC CCTTACTTTT CACGTTATCA GACGAAATAT 60 61 CGTCGTCGTC GTGAGGGTAA AACCGATTAT TACGCTCGTA AGCGTTTGAT TGCCCAGGCC 120 121 AAGAACAAAT ACAATGCTCC CAAGTACCGT TTGGTCGTTC GTTTCTCCAA TCGTTTCGTC 180 181 ACATGCCAAA TAGTTTCTTC CAGAGTAAAC GGTGACTATG TTCTTGCTCA CGCTCACTCT 240 241 TCTGAGCTTC CTCGTTACGG TATCAAATGG GGTTTGGCCA ACTGGACTGC CGCCTACGCT 300 301 ACCGGTCTTT TGGTCGCTCG TCGTGCTCTT GCTAAGGTTG GCCTTGCTGA TAAGTATGAG 360 361 GGTGTTACTG AACCTGAGGG TGAGTTCGAG CTCACTGAGG CTATTGAGGA TGGTCCTCGC 420 421 CCCTTCAAGG TTTTCTTGGA TGTTGGTTTG AAGCGTACTT CTACCGGTTC CCGTGTCTTT 480 481 GGTGCAATGA AGGGTGCTTC TGATGGTGGT TTGTTTATTC CCCACTCTCC CAACCGTTTC 540 541 CCTGGTTTCG ATATTGAAAC TGAGGAATTG GATGATGAGA CTCTCCGTAA GTATATCTAT 600 601 GGTGGTCATG TTGCTGAATA CATGGAGATG CTTATTGATG ATGATGAAGA GCGTTATCAA 660 661 AAGCAATTCT CTGGCTTGAT TGCTGATGGT ATTGAGAGCG ATCAACTTGA GGACATCTAT 720 721 GCCGAGGCTT ATGCCAAAAT CCGTGAGGAT CCTTCTTTCC AGAAGTCTGG TAAGGATGCT 780 781 GCTGCTTTCA AGGCTGAGTC TCTTAAGTAT ACTCAAAGGA AGCTTACTGC TGAAGAACGC 840 841 AAAGAGCGTT TCAACGCCAA GGTTATTGAG GCCGGTCGTG CTTAA 885 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Cytosolic large ribosomal subunit | |
Cellular Component | Nucleus | |
Molecular Function | 5S rRNA binding | |
Molecular Function | Structural constituent of ribosome | |
Biological Process | Cytoplasmic translation | |
Biological Process | Ribosomal large subunit assembly | |
Biological Process | Ribosome biogenesis |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Scc-0452 | Schizosaccharomyces cryophilus | 88.74 | 0.0 | 531 |
| LLPS-Scj-0168 | Schizosaccharomyces japonicus | 86.73 | 1e-177 | 499 |
| LLPS-Usm-0835 | Ustilago maydis | 69.55 | 2e-138 | 400 |
| LLPS-Spr-0808 | Sporisorium reilianum | 68.86 | 3e-136 | 394 |
| LLPS-Abg-1511 | Absidia glauca | 68.08 | 2e-114 | 339 |
| LLPS-Nec-1363 | Neurospora crassa | 68.06 | 3e-126 | 369 |
| LLPS-Fuo-0563 | Fusarium oxysporum | 67.82 | 4e-118 | 349 |
| LLPS-Fuv-0877 | Fusarium verticillioides | 67.68 | 4e-119 | 351 |
| LLPS-Nef-0656 | Neosartorya fischeri | 67.45 | 2e-126 | 372 |
| LLPS-Asg-0230 | Ashbya gossypii | 67.37 | 3e-134 | 389 |
| LLPS-Miv-0357 | Microbotryum violaceum | 67.01 | 6e-128 | 374 |
| LLPS-Mel-0114 | Melampsora laricipopulina | 66.67 | 9e-132 | 383 |
| LLPS-Ast-0161 | Aspergillus terreus | 66.56 | 7e-124 | 363 |
| LLPS-Kop-0492 | Komagataella pastoris | 66.55 | 4e-124 | 364 |
| LLPS-Asfu-0486 | Aspergillus fumigatus | 66.55 | 1e-116 | 345 |
| LLPS-Asc-0006 | Aspergillus clavatus | 66.44 | 6e-126 | 369 |
| LLPS-Crn-0686 | Cryptococcus neoformans | 66.09 | 7e-133 | 386 |
| LLPS-Blg-0888 | Blumeria graminis | 65.76 | 8e-128 | 373 |
| LLPS-Zyt-0801 | Zymoseptoria tritici | 65.76 | 2e-126 | 370 |
| LLPS-Gag-0184 | Gaeumannomyces graminis | 65.44 | 4e-122 | 359 |
| LLPS-Asn-0517 | Aspergillus nidulans | 65.32 | 2e-121 | 357 |
| LLPS-Sac-1185 | Saccharomyces cerevisiae | 65.25 | 6e-119 | 350 |
| LLPS-Scs-0504 | Sclerotinia sclerotiorum | 65.19 | 5e-127 | 371 |
| LLPS-Map-0266 | Magnaporthe poae | 65.1 | 8e-120 | 353 |
| LLPS-Asni-0005 | Aspergillus niger | 65.1 | 5e-123 | 361 |
| LLPS-Pug-0084 | Puccinia graminis | 65.05 | 3e-127 | 376 |
| LLPS-Lem-0380 | Leptosphaeria maculans | 64.98 | 4e-123 | 363 |
| LLPS-Mao-0464 | Magnaporthe oryzae | 64.98 | 1e-122 | 360 |
| LLPS-Aso-0049 | Aspergillus oryzae | 64.77 | 1e-122 | 360 |
| LLPS-Asf-0431 | Aspergillus flavus | 64.77 | 1e-122 | 360 |
| LLPS-Pyt-0049 | Pyrenophora teres | 64.65 | 2e-125 | 367 |
| LLPS-Pytr-0100 | Pyrenophora triticirepentis | 64.65 | 7e-126 | 368 |
| LLPS-Dos-0951 | Dothistroma septosporum | 64.41 | 1e-123 | 363 |
| LLPS-Put-0486 | Puccinia triticina | 64.36 | 7e-128 | 373 |
| LLPS-Trv-0486 | Trichoderma virens | 64.29 | 3e-122 | 359 |
| LLPS-Trr-1143 | Trichoderma reesei | 63.73 | 2e-120 | 355 |
| LLPS-Fus-0402 | Fusarium solani | 63.64 | 5e-123 | 361 |
| LLPS-Cog-0329 | Colletotrichum gloeosporioides | 62.71 | 9e-121 | 355 |
| LLPS-Tum-0162 | Tuber melanosporum | 62.33 | 8e-123 | 363 |
| LLPS-Ved-0350 | Verticillium dahliae | 62.24 | 6e-124 | 363 |
| LLPS-Yal-0227 | Yarrowia lipolytica | 62.2 | 1e-109 | 327 |
| LLPS-Orm-0709 | Oryza meridionalis | 62.0 | 1e-12 | 68.2 |
| LLPS-Coo-0196 | Colletotrichum orbiculare | 61.36 | 7e-119 | 350 |
| LLPS-Beb-0053 | Beauveria bassiana | 61.28 | 2e-118 | 349 |
| LLPS-Cogr-0713 | Colletotrichum graminicola | 61.13 | 4e-112 | 333 |
| LLPS-Cym-0758 | Cyanidioschyzon merolae | 59.76 | 2e-94 | 288 |
| LLPS-Phn-1047 | Phaeosphaeria nodorum | 59.74 | 1e-79 | 249 |
| LLPS-Hov-0554 | Hordeum vulgare | 56.17 | 8e-54 | 179 |
| LLPS-Icp-2533 | Ictalurus punctatus | 55.97 | 2e-91 | 281 |
| LLPS-Cis-0619 | Ciona savignyi | 55.95 | 2e-88 | 272 |
| LLPS-Vir-0706 | Vigna radiata | 55.9 | 1e-100 | 304 |
| LLPS-Glm-1391 | Glycine max | 55.56 | 3e-99 | 300 |
| LLPS-Phv-1758 | Phaseolus vulgaris | 55.56 | 1e-101 | 306 |
| LLPS-Xet-1505 | Xenopus tropicalis | 55.38 | 8e-97 | 294 |
| LLPS-Via-0974 | Vigna angularis | 55.21 | 1e-98 | 299 |
| LLPS-Sob-0419 | Sorghum bicolor | 55.21 | 3e-95 | 290 |
| LLPS-Prp-0368 | Prunus persica | 55.17 | 4e-97 | 295 |
| LLPS-Drm-1099 | Drosophila melanogaster | 54.9 | 8e-104 | 312 |
| LLPS-Hea-1749 | Helianthus annuus | 54.83 | 7e-98 | 297 |
| LLPS-Mae-0894 | Manihot esculenta | 54.83 | 1e-97 | 296 |
| LLPS-Sot-1786 | Solanum tuberosum | 54.73 | 2e-99 | 301 |
| LLPS-Sol-0689 | Solanum lycopersicum | 54.73 | 2e-99 | 301 |
| LLPS-Pot-2373 | Populus trichocarpa | 54.64 | 2e-95 | 291 |
| LLPS-Anc-1791 | Anolis carolinensis | 54.58 | 1e-94 | 288 |
| LLPS-Met-0852 | Medicago truncatula | 54.51 | 1e-97 | 296 |
| LLPS-Zem-0447 | Zea mays | 54.51 | 8e-95 | 289 |
| LLPS-Cus-0038 | Cucumis sativus | 54.48 | 2e-93 | 286 |
| LLPS-Mal-2161 | Mandrillus leucophaeus | 54.27 | 3e-80 | 251 |
| LLPS-Meg-1922 | Meleagris gallopavo | 54.22 | 1e-92 | 284 |
| LLPS-Gaga-0889 | Gallus gallus | 54.18 | 2e-93 | 285 |
| LLPS-Viv-0143 | Vitis vinifera | 54.14 | 2e-94 | 288 |
| LLPS-Orl-3004 | Oryzias latipes | 54.12 | 3e-94 | 288 |
| LLPS-Nia-0190 | Nicotiana attenuata | 54.05 | 2e-97 | 299 |
| LLPS-Sei-0697 | Setaria italica | 53.98 | 1e-92 | 283 |
| LLPS-Chr-0299 | Chlamydomonas reinhardtii | 53.82 | 2e-92 | 283 |
| LLPS-Tag-0392 | Taeniopygia guttata | 53.82 | 4e-92 | 282 |
| LLPS-Anp-0742 | Anas platyrhynchos | 53.82 | 2e-92 | 283 |
| LLPS-Sah-1565 | Sarcophilus harrisii | 53.78 | 7e-87 | 269 |
| LLPS-Tut-2032 | Tursiops truncatus | 53.75 | 5e-86 | 266 |
| LLPS-Aon-1895 | Aotus nancymaae | 53.75 | 8e-89 | 273 |
| LLPS-Sus-1496 | Sus scrofa | 53.75 | 6e-88 | 271 |
| LLPS-Ora-0460 | Ornithorhynchus anatinus | 53.75 | 5e-88 | 271 |
| LLPS-Caj-1931 | Callithrix jacchus | 53.75 | 8e-89 | 273 |
| LLPS-Mod-0715 | Monodelphis domestica | 53.75 | 2e-87 | 270 |
| LLPS-Ova-0258 | Ovis aries | 53.57 | 1e-85 | 266 |
| LLPS-Gor-2797 | Gossypium raimondii | 53.45 | 2e-95 | 290 |
| LLPS-Dio-2949 | Dipodomys ordii | 53.39 | 4e-87 | 269 |
| LLPS-Myl-3206 | Myotis lucifugus | 53.39 | 9e-87 | 268 |
| LLPS-Caf-1241 | Canis familiaris | 53.39 | 5e-87 | 269 |
| LLPS-Fia-2481 | Ficedula albicollis | 53.39 | 4e-92 | 283 |
| LLPS-Orc-1514 | Oryctolagus cuniculus | 53.39 | 5e-87 | 269 |
| LLPS-Paa-0339 | Papio anubis | 53.36 | 2e-87 | 270 |
| LLPS-Mup-0912 | Mustela putorius furo | 53.36 | 8e-86 | 266 |
| LLPS-Cea-1473 | Cercocebus atys | 53.36 | 2e-87 | 270 |
| LLPS-Maf-1163 | Macaca fascicularis | 53.36 | 2e-87 | 270 |
| LLPS-Poa-0504 | Pongo abelii | 53.36 | 2e-87 | 270 |
| LLPS-Cap-2437 | Cavia porcellus | 53.36 | 1e-87 | 270 |
| LLPS-Nol-2661 | Nomascus leucogenys | 53.36 | 2e-87 | 270 |
| LLPS-Pap-0232 | Pan paniscus | 53.36 | 2e-87 | 270 |
| LLPS-Hos-1888 | Homo sapiens | 53.36 | 2e-87 | 270 |
| LLPS-Sem-2012 | Selaginella moellendorffii | 53.26 | 2e-96 | 293 |
| LLPS-Tra-0622 | Triticum aestivum | 53.22 | 7e-92 | 282 |
| LLPS-Loa-2090 | Loxodonta africana | 53.17 | 4e-87 | 269 |
| LLPS-Brn-1120 | Brassica napus | 53.15 | 2e-94 | 288 |
| LLPS-Coc-0065 | Corchorus capsularis | 53.15 | 1e-93 | 286 |
| LLPS-Brr-0527 | Brassica rapa | 53.15 | 3e-94 | 288 |
| LLPS-Xim-2082 | Xiphophorus maculatus | 53.14 | 1e-87 | 270 |
| LLPS-Aim-1857 | Ailuropoda melanoleuca | 52.96 | 1e-85 | 266 |
| LLPS-Ran-1562 | Rattus norvegicus | 52.96 | 1e-82 | 258 |
| LLPS-Mum-0152 | Mus musculus | 52.96 | 4e-82 | 256 |
| LLPS-Fud-0603 | Fukomys damarensis | 52.96 | 3e-85 | 265 |
| LLPS-Eqc-1658 | Equus caballus | 52.96 | 4e-87 | 270 |
| LLPS-Php-1478 | Physcomitrella patens | 52.92 | 3e-93 | 285 |
| LLPS-Gog-2301 | Gorilla gorilla | 52.78 | 5e-84 | 261 |
| LLPS-Mam-1717 | Macaca mulatta | 52.78 | 3e-84 | 262 |
| LLPS-Pat-0203 | Pan troglodytes | 52.78 | 5e-84 | 261 |
| LLPS-Mua-2599 | Musa acuminata | 52.76 | 1e-93 | 287 |
| LLPS-Osl-0137 | Ostreococcus lucimarinus | 52.61 | 3e-84 | 262 |
| LLPS-Bot-0219 | Bos taurus | 52.57 | 3e-85 | 265 |
| LLPS-Mea-0606 | Mesocricetus auratus | 52.57 | 2e-81 | 255 |
| LLPS-Cas-1096 | Carlito syrichta | 52.57 | 1e-84 | 262 |
| LLPS-Arl-0431 | Arabidopsis lyrata | 52.43 | 1e-94 | 289 |
| LLPS-Fec-0970 | Felis catus | 52.4 | 2e-73 | 237 |
| LLPS-Brd-0710 | Brachypodium distachyon | 52.36 | 1e-90 | 279 |
| LLPS-Amt-0710 | Amborella trichopoda | 52.36 | 3e-86 | 267 |
| LLPS-Chs-0042 | Chlorocebus sabaeus | 52.17 | 3e-91 | 280 |
| LLPS-Bro-0823 | Brassica oleracea | 52.08 | 2e-92 | 283 |
| LLPS-Art-0439 | Arabidopsis thaliana | 52.08 | 4e-94 | 287 |
| LLPS-Ori-0163 | Oryza indica | 51.7 | 7e-92 | 282 |
| LLPS-Ors-0809 | Oryza sativa | 51.7 | 7e-92 | 282 |
| LLPS-Lac-1296 | Latimeria chalumnae | 51.57 | 1e-96 | 294 |
| LLPS-Thc-0123 | Theobroma cacao | 51.41 | 4e-89 | 276 |
| LLPS-Otg-0319 | Otolemur garnettii | 51.39 | 4e-88 | 272 |
| LLPS-Orbr-0695 | Oryza brachyantha | 51.36 | 2e-90 | 278 |
| LLPS-Tru-1231 | Triticum urartu | 51.35 | 1e-86 | 268 |
| LLPS-Scf-1489 | Scleropages formosus | 51.23 | 4e-95 | 291 |
| LLPS-Leo-1477 | Lepisosteus oculatus | 51.22 | 1e-98 | 300 |
| LLPS-Cii-0486 | Ciona intestinalis | 51.22 | 5e-97 | 295 |
| LLPS-Asm-1183 | Astyanax mexicanus | 51.22 | 1e-97 | 296 |
| LLPS-Ten-2142 | Tetraodon nigroviridis | 51.22 | 2e-96 | 293 |
| LLPS-Dar-1533 | Danio rerio | 51.22 | 1e-97 | 296 |
| LLPS-Gas-0701 | Galdieria sulphuraria | 51.04 | 7e-90 | 276 |
| LLPS-Tar-2588 | Takifugu rubripes | 50.89 | 5e-93 | 284 |
| LLPS-Cae-0211 | Caenorhabditis elegans | 50.69 | 4e-88 | 271 |
| LLPS-Scm-1053 | Scophthalmus maximus | 50.52 | 3e-95 | 290 |
| LLPS-Chc-0259 | Chondrus crispus | 50.51 | 2e-93 | 285 |
| LLPS-Pes-0625 | Pelodiscus sinensis | 50.25 | 1e-63 | 207 |
| LLPS-Ict-1126 | Ictidomys tridecemlineatus | 50.2 | 3e-78 | 246 |
| LLPS-Pof-1289 | Poecilia formosa | 50.17 | 4e-95 | 290 |
| LLPS-Orn-1935 | Oreochromis niloticus | 50.17 | 5e-95 | 290 |
| LLPS-Gaa-2102 | Gasterosteus aculeatus | 49.83 | 5e-94 | 287 |
| LLPS-Rhb-1002 | Rhinopithecus bieti | 49.13 | 1e-88 | 273 |
| LLPS-Man-1840 | Macaca nemestrina | 48.75 | 1e-77 | 244 |
| LLPS-Org-0460 | Oryza glaberrima | 47.98 | 6e-46 | 161 |
| LLPS-Urm-0857 | Ursus maritimus | 47.53 | 2e-73 | 237 |
| LLPS-Dac-0361 | Daucus carota | 46.28 | 5e-75 | 237 |
| LLPS-Lep-0337 | Leersia perrieri | 44.7 | 3e-23 | 98.2 |
| LLPS-Ere-0355 | Erinaceus europaeus | 36.68 | 2e-32 | 125 |