• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sah-4044
ME3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Malic enzyme
Gene Name: ME3
Ensembl Gene: ENSSHAG00000011265.1
Ensembl Protein: ENSSHAP00000013177.1
Organism: Sarcophilus harrisii
Taxa ID: 9305
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granule, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSLFNQGAR  MALQGRVGCA  FLFRAPPLTG  IQLVRASSSS  GPAGSHPVPL  ALKKRGYDVT  60
61    RNPHLNKGMA  FTLEERLQLG  IHGLIPPCFL  SQDVQLLRVM  RYYEKQPSDL  DKYIILMTLQ  120
121   DRNEKLFYRV  LTSDVEKFMP  IVYTPTVGLA  CQQYGLTFRR  PRGLFITIHD  KGHIATMLNS  180
181   WPEDNIKAVV  VTDGERILGL  GDLGCYGMGI  PVGKLALYTA  CGGVNPQHCL  PVLLDVGTNN  240
241   EALLKDPLYI  GLKHKRVRGK  EYDELIDEFM  QAVTNKFGIN  CLIQFEDFAN  ANAFRLLHKY  300
301   RNKYCMFNDD  IQGTASVAVA  GIFAALRITK  NKLSNHVFVF  QGAGEAAMGI  AHLIVMALEK  360
361   EGIPKAEATK  KIWMVDSKGL  IVKGRSHLNH  EKEVFAQDHA  EVNTLEEVVR  QVKPTAIIGV  420
421   AAVAGAFTDQ  ILKDMASFNK  RPIIFALSNP  TSKAECTAEK  CYRLTEGRGI  FASGSPFDKV  480
481   TLEDGRTFFP  GQGNNAYVFP  GVALGVIACG  VRHIPEEIFL  LTAEHIAQEV  SDEHLSQGRL  540
541   YPPLSTIRDV  SLRIAVKVLD  YAYKHSLASW  YPEPEDKEAF  VRSLVYTPEY  DSFVLDSYTW  600
601   PKEAAEVQEI  610
Nucleotide CDS Sequence (FASTA)
1     ATGAGTTCTC  TCTTCAACCA  GGGAGCTCGG  ATGGCTCTCC  AAGGGAGGGT  CGGCTGTGCC  60
61    TTCCTGTTCC  GGGCGCCCCC  TTTGACAGGC  ATCCAGCTGG  TACGGGCCAG  CAGCAGCTCC  120
121   GGGCCCGCAG  GGTCCCATCC  AGTGCCCTTG  GCCTTGAAGA  AACGGGGCTA  CGACGTCACC  180
181   AGAAACCCGC  ATCTCAACAA  GGGAATGGCA  TTTACACTAG  AAGAAAGGCT  GCAGCTTGGC  240
241   ATCCATGGCT  TAATACCTCC  TTGCTTCTTG  AGCCAAGATG  TCCAGCTCCT  CCGGGTTATG  300
301   AGATACTACG  AGAAACAGCC  CAGTGATCTG  GACAAGTACA  TCATTCTCAT  GACTCTCCAA  360
361   GACCGGAATG  AGAAACTTTT  CTACCGAGTT  CTTACATCGG  ATGTAGAGAA  GTTCATGCCT  420
421   ATTGTTTATA  CACCCACAGT  GGGGCTGGCT  TGTCAGCAGT  ATGGCCTGAC  CTTCCGTAGA  480
481   CCACGTGGGC  TCTTTATCAC  CATTCATGAC  AAAGGTCACA  TTGCTACAAT  GCTGAACTCC  540
541   TGGCCAGAAG  ACAATATTAA  GGCTGTGGTG  GTGACAGATG  GAGAACGCAT  CTTGGGCCTT  600
601   GGAGATCTGG  GCTGCTATGG  CATGGGCATC  CCAGTGGGCA  AACTCGCACT  GTATACTGCA  660
661   TGTGGTGGAG  TAAATCCACA  GCACTGTCTT  CCAGTTCTGC  TAGATGTTGG  CACTAACAAT  720
721   GAGGCCCTGC  TGAAAGACCC  TCTGTATATT  GGACTGAAGC  ACAAGCGTGT  ACGTGGGAAA  780
781   GAATATGACG  AGTTGATTGA  TGAGTTCATG  CAAGCAGTGA  CTAACAAGTT  TGGAATAAAT  840
841   TGCCTCATCC  AGTTTGAAGA  TTTTGCCAAC  GCCAATGCCT  TCCGCCTACT  CCACAAATAT  900
901   CGGAACAAGT  ACTGTATGTT  CAATGATGAC  ATCCAAGGCA  CTGCTTCTGT  GGCTGTTGCT  960
961   GGTATTTTTG  CTGCCTTACG  GATTACCAAA  AACAAGCTCT  CCAATCACGT  GTTTGTTTTC  1020
1021  CAAGGAGCAG  GAGAGGCAGC  TATGGGAATT  GCCCACCTCA  TTGTCATGGC  CCTGGAGAAA  1080
1081  GAAGGCATCC  CAAAGGCAGA  GGCCACCAAG  AAGATCTGGA  TGGTAGATTC  CAAGGGGCTC  1140
1141  ATTGTGAAGG  GAAGGAGTCA  CCTGAACCAT  GAGAAGGAGG  TGTTTGCTCA  GGATCATGCA  1200
1201  GAAGTGAATA  CTCTGGAGGA  AGTGGTCCGG  CAAGTGAAAC  CCACAGCCAT  CATAGGGGTG  1260
1261  GCTGCTGTTG  CAGGAGCGTT  CACCGACCAG  ATTCTGAAGG  ATATGGCCTC  TTTCAACAAA  1320
1321  CGACCCATCA  TCTTTGCCTT  AAGCAATCCC  ACGAGCAAAG  CTGAGTGCAC  CGCTGAGAAA  1380
1381  TGCTACCGTC  TCACAGAGGG  CCGAGGGATC  TTTGCCAGCG  GGAGTCCATT  TGACAAAGTA  1440
1441  ACCCTGGAAG  ATGGCAGGAC  CTTTTTCCCT  GGGCAAGGAA  ACAACGCCTA  CGTGTTCCCC  1500
1501  GGAGTGGCGC  TGGGTGTCAT  CGCCTGTGGA  GTCCGGCACA  TCCCTGAAGA  GATCTTCCTC  1560
1561  CTCACGGCTG  AGCATATTGC  CCAGGAGGTC  TCTGATGAGC  ATCTCTCCCA  AGGGCGGCTC  1620
1621  TACCCACCAC  TCAGCACCAT  TCGGGATGTG  TCCCTGAGAA  TTGCAGTCAA  GGTCCTTGAC  1680
1681  TACGCCTACA  AACACAGCCT  GGCCTCGTGG  TACCCAGAGC  CTGAGGACAA  GGAGGCCTTT  1740
1741  GTGAGATCTC  TGGTCTACAC  TCCAGAATAT  GACTCCTTCG  TGCTGGACAG  CTACACATGG  1800
1801  CCCAAGGAAG  CCGCAGAAGT  CCAGGAGATC  TGA  1833

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caf-4572Canis familiaris90.930.01057
LLPS-Aon-1276Aotus nancymaae85.410.01061
LLPS-Anc-3738Anolis carolinensis85.360.01001
LLPS-Gog-4066Gorilla gorilla85.250.01055
LLPS-Cap-2417Cavia porcellus85.110.01053
LLPS-Lac-1024Latimeria chalumnae84.140.0 987
LLPS-Icp-1982Ictalurus punctatus82.080.0 971
LLPS-Tar-2656Takifugu rubripes80.470.0 955
LLPS-Orl-2971Oryzias latipes80.290.0 954
LLPS-Gaa-0995Gasterosteus aculeatus80.110.0 945
LLPS-Asm-4181Astyanax mexicanus76.620.0 898
LLPS-Mod-0356Monodelphis domestica76.080.0 899
LLPS-Pes-1982Pelodiscus sinensis75.310.0 890
LLPS-Poa-3463Pongo abelii74.610.0 805
LLPS-Anp-1315Anas platyrhynchos74.330.0 894
LLPS-Loa-0786Loxodonta africana74.230.0 882
LLPS-Gaga-1619Gallus gallus74.150.0 889
LLPS-Sus-2054Sus scrofa73.870.0 876
LLPS-Mup-1767Mustela putorius furo73.870.0 877
LLPS-Meg-0012Meleagris gallopavo73.870.0 884
LLPS-Fia-1384Ficedula albicollis73.710.0 862
LLPS-Fec-2064Felis catus73.690.0 879
LLPS-Ova-1775Ovis aries73.330.0 846
LLPS-Aim-0068Ailuropoda melanoleuca73.160.0 852
LLPS-Bot-0760Bos taurus73.150.0 866
LLPS-Hos-4051Homo sapiens73.150.0 869
LLPS-Ict-4378Ictidomys tridecemlineatus73.150.0 875
LLPS-Pap-2219Pan paniscus73.10.0 867
LLPS-Cea-1389Cercocebus atys72.970.0 873
LLPS-Mal-0921Mandrillus leucophaeus72.970.0 873
LLPS-Paa-0970Papio anubis72.970.0 873
LLPS-Man-2281Macaca nemestrina72.970.0 873
LLPS-Pat-4206Pan troglodytes72.970.0 868
LLPS-Urm-0492Ursus maritimus72.880.0 848
LLPS-Maf-4048Macaca fascicularis72.790.0 871
LLPS-Chs-0429Chlorocebus sabaeus72.790.0 871
LLPS-Mam-2311Macaca mulatta72.790.0 871
LLPS-Mum-3978Mus musculus72.610.0 865
LLPS-Orc-2848Oryctolagus cuniculus72.610.0 868
LLPS-Nol-2241Nomascus leucogenys72.610.0 865
LLPS-Ran-3696Rattus norvegicus72.430.0 860
LLPS-Eqc-3812Equus caballus72.430.0 861
LLPS-Caj-0095Callithrix jacchus72.250.0 868
LLPS-Fud-0211Fukomys damarensis71.530.0 854
LLPS-Rhb-1750Rhinopithecus bieti71.530.0 847
LLPS-Otg-2367Otolemur garnettii71.510.0 831
LLPS-Myl-0213Myotis lucifugus69.680.0 811
LLPS-Scf-0910Scleropages formosus60.440.0 689
LLPS-Scm-0176Scophthalmus maximus60.440.0 691
LLPS-Leo-3091Lepisosteus oculatus60.250.0 696
LLPS-Xim-0077Xiphophorus maculatus60.250.0 691
LLPS-Dar-2827Danio rerio60.070.0 686
LLPS-Ten-2551Tetraodon nigroviridis59.640.0 694
LLPS-Pof-0766Poecilia formosa59.420.0 682
LLPS-Tag-1058Taeniopygia guttata59.210.0 685
LLPS-Orn-0698Oreochromis niloticus58.680.0 679
LLPS-Dio-2619Dipodomys ordii58.320.0 665
LLPS-Xet-0860Xenopus tropicalis58.080.0 670
LLPS-Ora-1892Ornithorhynchus anatinus57.860.0 674
LLPS-Cas-2508Carlito syrichta57.780.0 664
LLPS-Drm-2204Drosophila melanogaster57.040.0 636
LLPS-Cae-1694Caenorhabditis elegans55.20.0 613
LLPS-Sol-1417Solanum lycopersicum53.150.0 583
LLPS-Thc-0091Theobroma cacao52.960.0 588
LLPS-Sot-1606Solanum tuberosum52.960.0 581
LLPS-Coc-1926Corchorus capsularis52.960.0 587
LLPS-Gor-2624Gossypium raimondii52.590.0 566
LLPS-Prp-1283Prunus persica52.590.0 578
LLPS-Sei-2079Setaria italica52.580.0 570
LLPS-Arl-0588Arabidopsis lyrata52.410.0 568
LLPS-Mae-1088Manihot esculenta52.220.0 568
LLPS-Art-2177Arabidopsis thaliana52.220.0 567
LLPS-Zem-0606Zea mays52.220.0 581
LLPS-Sem-1967Selaginella moellendorffii52.040.0 564
LLPS-Met-1289Medicago truncatula52.040.0 566
LLPS-Mua-2258Musa acuminata51.850.0 575
LLPS-Amt-0317Amborella trichopoda51.850.0 587
LLPS-Nia-1152Nicotiana attenuata51.850.0 582
LLPS-Sob-1172Sorghum bicolor51.670.0 575
LLPS-Bro-2151Brassica oleracea51.670.0 573
LLPS-Orni-1754Oryza nivara51.580.0 565
LLPS-Hea-0388Helianthus annuus51.480.0 576
LLPS-Orb-0328Oryza barthii51.480.0 569
LLPS-Vir-0386Vigna radiata51.480.0 563
LLPS-Brd-1466Brachypodium distachyon51.480.0 580
LLPS-Orp-2288Oryza punctata51.480.0 564
LLPS-Viv-2336Vitis vinifera51.480.0 563
LLPS-Ors-2221Oryza sativa51.480.0 569
LLPS-Org-1342Oryza glaberrima51.480.0 569
LLPS-Orr-2325Oryza rufipogon51.480.0 569
LLPS-Pot-2392Populus trichocarpa51.40.0 561
LLPS-Lep-1639Leersia perrieri51.30.0 563
LLPS-Orm-1217Oryza meridionalis51.30.0 566
LLPS-Brr-2530Brassica rapa51.210.0 543
LLPS-Hov-0083Hordeum vulgare51.130.0 563
LLPS-Cus-2224Cucumis sativus51.110.0 573
LLPS-Phv-2007Phaseolus vulgaris51.110.0 568
LLPS-Orbr-1769Oryza brachyantha51.110.0 562
LLPS-Via-1147Vigna angularis51.020.0 567
LLPS-Brn-2970Brassica napus51.010.0 569
LLPS-Tru-1881Triticum urartu50.880.0 538
LLPS-Dac-1666Daucus carota50.740.0 554
LLPS-Tra-0267Triticum aestivum50.740.0 570
LLPS-Orgl-1507Oryza glumaepatula50.740.0 578
LLPS-Php-1330Physcomitrella patens50.370.0 541
LLPS-Glm-1833Glycine max50.370.0 559
LLPS-Cym-1077Cyanidioschyzon merolae48.450.0 543
LLPS-Chc-0928Chondrus crispus46.062e-161 481
LLPS-Gas-1332Galdieria sulphuraria45.453e-159 477
LLPS-Lem-0462Leptosphaeria maculans42.373e-134 412
LLPS-Pug-1105Puccinia graminis42.231e-120 378
LLPS-Blg-0896Blumeria graminis42.216e-132 407
LLPS-Osl-0457Ostreococcus lucimarinus41.732e-139 424
LLPS-Spr-1168Sporisorium reilianum41.643e-146 444
LLPS-Ori-1302Oryza indica41.077e-128 395
LLPS-Usm-0647Ustilago maydis40.913e-143 436
LLPS-Map-1054Magnaporthe poae40.842e-130 409
LLPS-Mel-1393Melampsora laricipopulina40.362e-117 368
LLPS-Nec-1485Neurospora crassa40.246e-115 364
LLPS-Coo-1342Colletotrichum orbiculare39.323e-113 358
LLPS-Tum-1629Tuber melanosporum39.326e-115 362
LLPS-Cogr-1170Colletotrichum graminicola39.143e-117 369
LLPS-Fuv-1440Fusarium verticillioides38.893e-99 318
LLPS-Cog-0336Colletotrichum gloeosporioides38.781e-108 346
LLPS-Sac-0134Saccharomyces cerevisiae38.748e-100 325
LLPS-Asg-0603Ashbya gossypii38.722e-92 304
LLPS-Crn-1238Cryptococcus neoformans37.853e-104 335
LLPS-Fus-1356Fusarium solani37.844e-112 355
LLPS-Zyt-1099Zymoseptoria tritici37.836e-117 367
LLPS-Mao-0666Magnaporthe oryzae37.739e-113 357
LLPS-Trr-1590Trichoderma reesei37.662e-106 340
LLPS-Beb-1528Beauveria bassiana37.551e-104 335
LLPS-Trv-1547Trichoderma virens37.481e-107 343
LLPS-Ved-0958Verticillium dahliae37.443e-77 260
LLPS-Ast-0283Aspergillus terreus37.429e-83 274
LLPS-Dos-0866Dothistroma septosporum37.369e-107 341
LLPS-Miv-0944Microbotryum violaceum37.283e-111 353
LLPS-Scs-1115Sclerotinia sclerotiorum37.258e-110 349
LLPS-Gag-0969Gaeumannomyces graminis37.192e-106 340
LLPS-Asc-1559Aspergillus clavatus36.872e-109 347
LLPS-Yal-0723Yarrowia lipolytica36.827e-105 337
LLPS-Asfu-1561Aspergillus fumigatus36.789e-104 332
LLPS-Nef-1404Neosartorya fischeri36.413e-104 334
LLPS-Abg-1724Absidia glauca36.26e-101 325
LLPS-Pytr-0825Pyrenophora triticirepentis36.02e-109 348
LLPS-Asni-1554Aspergillus niger35.916e-110 350
LLPS-Pyt-1425Pyrenophora teres35.829e-109 346
LLPS-Fuo-0756Fusarium oxysporum35.791e-102 330
LLPS-Kop-0860Komagataella pastoris35.691e-98 320
LLPS-Scj-0761Schizosaccharomyces japonicus35.573e-98 317
LLPS-Asf-1593Aspergillus flavus34.834e-103 331
LLPS-Aso-1388Aspergillus oryzae34.834e-103 331
LLPS-Asn-1306Aspergillus nidulans34.823e-104 334
LLPS-Scc-0037Schizosaccharomyces cryophilus34.71e-93 306
LLPS-Phn-1588Phaeosphaeria nodorum34.233e-93 306
LLPS-Scp-1610Schizosaccharomyces pombe32.198e-88 290