• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-4572
ME3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Malic enzyme
Gene Name: ME3
Ensembl Gene: ENSCAFG00000004407.3
Ensembl Protein: ENSCAFP00000006606.3
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granule, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGAALGRGAR  PGLLRGKAWG  AVPRWTPSAP  GRGCRSRAGP  ARPVPLKKRG  YDVTRNPHLN  60
61    KGMAFTLEER  LQLGIHGLIP  PCFLSQDVQL  LRIMRYYERQ  QSDLDKYIIL  MTLQDRNEKL  120
121   FYRVLTSDVE  KFMPIVYTPT  VGLACQQYGL  TFRRPRGLFI  TIHDKGHLAT  MLNSWPEDDI  180
181   KAVVVTDGER  ILGLGDLGCY  GMGIPVGKLA  LYTACGGVSP  QQCLPVLLDV  GTNNEELLRD  240
241   PLYIGLKHQR  VRGKEYDDLL  DEFMQAVTDK  FGINCLIQFE  DFANANAFRL  LNKYRNKYCM  300
301   FNDDIQGTAS  VAVAGILAAL  RITKNKLSNH  VFVFQGAGEA  AMGIAHLLVM  ALEKEGVPKA  360
361   EATRKIWMVD  SKGLIVKGRS  HLNHEKEMFA  QDHPEVKSLE  EVVRLVKPTA  IIGVAAIAGA  420
421   FTEQILRDMA  SFHERPIIFA  LSNPTSKAEC  TAEKCYRVTE  GRGIFASGSP  FKSVTLEDGR  480
481   TFIPGQGNNA  YVFPGVALGV  IAGGIRHIPD  EIFLLTAEQI  AQEVSEQHLS  QGRLYPPLST  540
541   IRDVSLRIAI  KVLDFAYKHN  LASYYPEPKD  KEAFVRSLVY  TPDYDSFTLD  SYTWPKEAMN  600
601   VQTV  604
Nucleotide CDS Sequence (FASTA)
1     ATGGGCGCCG  CGCTGGGCAG  GGGCGCGCGG  CCGGGGCTCC  TGCGGGGTAA  GGCTTGGGGC  60
61    GCCGTCCCGC  GCTGGACGCC  TTCGGCTCCG  GGCCGCGGCT  GCCGTTCCAG  GGCCGGCCCG  120
121   GCCCGCCCCG  TGCCCCTGAA  GAAGCGCGGG  TACGACGTCA  CCAGGAACCC  GCATCTCAAC  180
181   AAGGGGATGG  CCTTTACACT  TGAAGAAAGG  CTGCAGCTTG  GAATCCATGG  CCTGATCCCT  240
241   CCCTGCTTCC  TGAGCCAGGA  CGTCCAGCTT  CTCCGGATCA  TGAGATACTA  TGAGCGGCAG  300
301   CAGAGTGACC  TGGACAAGTA  CATCATTCTC  ATGACGCTCC  AAGACCGGAA  TGAGAAGCTC  360
361   TTCTACCGAG  TGCTGACATC  AGATGTGGAG  AAATTCATGC  CCATCGTATA  CACTCCCACT  420
421   GTGGGGCTGG  CCTGTCAGCA  GTATGGCCTG  ACCTTCCGCA  GGCCCCGTGG  GCTGTTCATC  480
481   ACCATTCATG  ACAAAGGCCA  TCTTGCAACA  ATGCTGAACT  CTTGGCCAGA  AGACGATATT  540
541   AAGGCCGTGG  TGGTAACCGA  TGGGGAGCGC  ATCCTGGGCC  TGGGAGACCT  GGGCTGCTAT  600
601   GGCATGGGCA  TCCCCGTGGG  CAAGCTGGCC  CTGTACACGG  CATGTGGAGG  GGTCAGCCCG  660
661   CAGCAATGCC  TCCCCGTCCT  GCTGGATGTC  GGCACCAACA  ACGAGGAGCT  GCTCAGAGAC  720
721   CCTCTGTACA  TTGGGCTGAA  ACACCAGCGC  GTGCGTGGGA  AGGAGTACGA  TGACCTGCTG  780
781   GACGAGTTCA  TGCAGGCTGT  GACAGACAAG  TTTGGAATAA  ATTGCCTCAT  CCAATTTGAA  840
841   GACTTTGCCA  ATGCCAATGC  CTTCCGTCTG  CTCAACAAAT  ACCGCAACAA  GTACTGCATG  900
901   TTCAATGATG  ACATCCAAGG  CACAGCCTCC  GTCGCTGTGG  CAGGGATCCT  GGCTGCTCTA  960
961   CGAATCACTA  AGAACAAGCT  CTCCAATCAT  GTGTTTGTTT  TCCAAGGTGC  AGGTGAGGCA  1020
1021  GCCATGGGCA  TCGCACACCT  CCTTGTCATG  GCCCTGGAAA  AAGAAGGTGT  ACCCAAGGCG  1080
1081  GAGGCTACAA  GGAAGATCTG  GATGGTGGAC  TCCAAGGGAC  TCATTGTCAA  GGGGAGGAGC  1140
1141  CACCTAAACC  ATGAGAAGGA  GATGTTTGCC  CAGGACCATC  CTGAAGTGAA  GAGCCTGGAG  1200
1201  GAGGTGGTGA  GGCTGGTGAA  GCCCACGGCC  ATCATAGGTG  TTGCTGCCAT  CGCAGGAGCC  1260
1261  TTCACGGAGC  AGATTCTGAG  GGACATGGCC  TCCTTCCACG  AGCGCCCTAT  CATCTTTGCC  1320
1321  CTGAGCAACC  CCACCAGCAA  GGCCGAGTGC  ACGGCTGAGA  AGTGCTACCG  GGTCACTGAG  1380
1381  GGCCGAGGGA  TCTTTGCCAG  TGGAAGTCCT  TTTAAGAGCG  TGACTCTAGA  AGATGGCAGG  1440
1441  ACCTTCATTC  CTGGGCAAGG  AAACAATGCC  TATGTGTTCC  CTGGAGTGGC  TCTGGGAGTC  1500
1501  ATTGCTGGCG  GGATCCGGCA  CATCCCAGAT  GAGATCTTCC  TCCTGACGGC  AGAGCAAATT  1560
1561  GCCCAAGAGG  TCTCTGAGCA  GCATTTGTCC  CAGGGGAGAT  TGTACCCACC  ACTCAGCACC  1620
1621  ATCCGAGATG  TGTCTCTGAG  AATCGCCATC  AAAGTCCTCG  ACTTCGCGTA  CAAACACAAC  1680
1681  CTGGCCTCCT  ACTACCCGGA  GCCCAAGGAC  AAGGAGGCTT  TTGTAAGATC  CCTGGTCTAC  1740
1741  ACTCCAGATT  ATGACTCCTT  TACACTGGAC  AGCTATACTT  GGCCCAAGGA  AGCCATGAAT  1800
1801  GTTCAAACAG  TCTGA  1815

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gog-4066Gorilla gorilla96.940.01164
LLPS-Aon-1276Aotus nancymaae96.60.01162
LLPS-Cap-2417Cavia porcellus94.730.01141
LLPS-Sah-4044Sarcophilus harrisii90.930.01057
LLPS-Anc-3738Anolis carolinensis81.940.0 989
LLPS-Lac-1024Latimeria chalumnae81.330.0 972
LLPS-Icp-1982Ictalurus punctatus79.760.0 978
LLPS-Tar-2656Takifugu rubripes78.780.0 974
LLPS-Orl-2971Oryzias latipes77.950.0 956
LLPS-Gaa-0995Gasterosteus aculeatus77.30.0 951
LLPS-Pes-1982Pelodiscus sinensis75.320.0 883
LLPS-Mod-0356Monodelphis domestica75.180.0 891
LLPS-Asm-4181Astyanax mexicanus75.00.0 891
LLPS-Sus-2054Sus scrofa74.10.0 871
LLPS-Loa-0786Loxodonta africana73.790.0 875
LLPS-Ova-1775Ovis aries73.750.0 841
LLPS-Poa-3463Pongo abelii73.750.0 801
LLPS-Anp-1315Anas platyrhynchos73.710.0 884
LLPS-Ict-4378Ictidomys tridecemlineatus73.560.0 875
LLPS-Bot-0760Bos taurus73.380.0 861
LLPS-Fia-1384Ficedula albicollis73.350.0 852
LLPS-Cea-1389Cercocebus atys73.20.0 870
LLPS-Mup-1767Mustela putorius furo73.20.0 866
LLPS-Mal-0921Mandrillus leucophaeus73.20.0 870
LLPS-Paa-0970Papio anubis73.20.0 870
LLPS-Fec-2064Felis catus73.20.0 870
LLPS-Hos-4051Homo sapiens73.20.0 865
LLPS-Man-2281Macaca nemestrina73.20.0 870
LLPS-Pap-2219Pan paniscus73.150.0 863
LLPS-Chs-0429Chlorocebus sabaeus73.020.0 868
LLPS-Maf-4048Macaca fascicularis73.020.0 868
LLPS-Pat-4206Pan troglodytes73.020.0 864
LLPS-Mam-2311Macaca mulatta73.020.0 868
LLPS-Mum-3978Mus musculus72.840.0 860
LLPS-Aim-0068Ailuropoda melanoleuca72.840.0 845
LLPS-Orc-2848Oryctolagus cuniculus72.840.0 868
LLPS-Meg-0012Meleagris gallopavo72.840.0 870
LLPS-Nol-2241Nomascus leucogenys72.840.0 862
LLPS-Urm-0492Ursus maritimus72.560.0 840
LLPS-Caj-0095Callithrix jacchus72.480.0 865
LLPS-Eqc-3812Equus caballus72.480.0 856
LLPS-Ran-3696Rattus norvegicus72.30.0 855
LLPS-Rhb-1750Rhinopithecus bieti72.120.0 847
LLPS-Fud-0211Fukomys damarensis71.940.0 852
LLPS-Otg-2367Otolemur garnettii71.740.0 823
LLPS-Myl-0213Myotis lucifugus71.270.0 807
LLPS-Gaga-1619Gallus gallus71.040.0 878
LLPS-Tag-1058Taeniopygia guttata59.490.0 692
LLPS-Dar-2827Danio rerio59.350.0 687
LLPS-Leo-3091Lepisosteus oculatus59.150.0 697
LLPS-Xim-0077Xiphophorus maculatus58.790.0 692
LLPS-Pof-0766Poecilia formosa58.70.0 682
LLPS-Ten-2551Tetraodon nigroviridis58.580.0 692
LLPS-Scm-0176Scophthalmus maximus58.320.0 687
LLPS-Scf-0910Scleropages formosus58.30.0 683
LLPS-Orn-0698Oreochromis niloticus57.910.0 677
LLPS-Xet-0860Xenopus tropicalis57.770.0 676
LLPS-Ora-1892Ornithorhynchus anatinus57.680.0 674
LLPS-Dio-2619Dipodomys ordii56.760.0 647
LLPS-Cas-2508Carlito syrichta56.330.0 651
LLPS-Drm-2204Drosophila melanogaster56.320.0 633
LLPS-Cae-1694Caenorhabditis elegans55.00.0 611
LLPS-Sol-1417Solanum lycopersicum52.590.0 579
LLPS-Sot-1606Solanum tuberosum52.410.0 578
LLPS-Thc-0091Theobroma cacao52.040.0 584
LLPS-Met-1289Medicago truncatula51.850.0 567
LLPS-Zem-0606Zea mays51.850.0 575
LLPS-Prp-1283Prunus persica51.850.0 577
LLPS-Arl-0588Arabidopsis lyrata51.670.0 569
LLPS-Gor-2624Gossypium raimondii51.670.0 565
LLPS-Art-2177Arabidopsis thaliana51.670.0 569
LLPS-Sem-1967Selaginella moellendorffii51.580.0 556
LLPS-Orb-0328Oryza barthii51.480.0 574
LLPS-Sei-2079Setaria italica51.480.0 568
LLPS-Ors-2221Oryza sativa51.480.0 574
LLPS-Orp-2288Oryza punctata51.480.0 569
LLPS-Org-1342Oryza glaberrima51.480.0 574
LLPS-Orr-2325Oryza rufipogon51.480.0 574
LLPS-Orni-1754Oryza nivara51.390.0 571
LLPS-Mua-2258Musa acuminata51.30.0 570
LLPS-Lep-1639Leersia perrieri51.30.0 566
LLPS-Sob-1172Sorghum bicolor51.30.0 572
LLPS-Orm-1217Oryza meridionalis51.30.0 571
LLPS-Nia-1152Nicotiana attenuata51.110.0 581
LLPS-Bro-2151Brassica oleracea51.110.0 575
LLPS-Tru-1881Triticum urartu51.080.0 541
LLPS-Brr-2530Brassica rapa51.020.0 541
LLPS-Mae-1088Manihot esculenta50.930.0 560
LLPS-Amt-0317Amborella trichopoda50.930.0 576
LLPS-Php-1330Physcomitrella patens50.740.0 542
LLPS-Vir-0386Vigna radiata50.740.0 561
LLPS-Viv-2336Vitis vinifera50.740.0 562
LLPS-Pot-2392Populus trichocarpa50.650.0 558
LLPS-Hea-0388Helianthus annuus50.560.0 573
LLPS-Orbr-1769Oryza brachyantha50.560.0 560
LLPS-Cym-1077Cyanidioschyzon merolae50.540.0 549
LLPS-Coc-1926Corchorus capsularis50.540.0 583
LLPS-Brn-2970Brassica napus50.460.0 572
LLPS-Cus-2224Cucumis sativus50.370.0 571
LLPS-Phv-2007Phaseolus vulgaris50.370.0 563
LLPS-Brd-1466Brachypodium distachyon50.190.0 570
LLPS-Dac-1666Daucus carota50.00.0 553
LLPS-Glm-1833Glycine max50.00.0 555
LLPS-Via-1147Vigna angularis49.910.0 559
LLPS-Hov-0083Hordeum vulgare49.810.0 554
LLPS-Tra-0267Triticum aestivum49.440.0 561
LLPS-Orgl-1507Oryza glumaepatula49.440.0 569
LLPS-Chc-0928Chondrus crispus46.241e-161 481
LLPS-Gas-1332Galdieria sulphuraria46.145e-158 474
LLPS-Lem-0462Leptosphaeria maculans42.774e-133 409
LLPS-Ori-1302Oryza indica41.618e-129 397
LLPS-Osl-0457Ostreococcus lucimarinus41.41e-137 420
LLPS-Blg-0896Blumeria graminis41.393e-126 392
LLPS-Pug-1105Puccinia graminis41.279e-119 373
LLPS-Map-1054Magnaporthe poae41.11e-131 411
LLPS-Spr-1168Sporisorium reilianum40.552e-139 426
LLPS-Usm-0647Ustilago maydis40.368e-140 427
LLPS-Mel-1393Melampsora laricipopulina40.04e-119 372
LLPS-Fuv-1440Fusarium verticillioides39.961e-100 322
LLPS-Nec-1485Neurospora crassa39.716e-113 359
LLPS-Cogr-1170Colletotrichum graminicola39.684e-119 373
LLPS-Coo-1342Colletotrichum orbiculare39.326e-113 357
LLPS-Tum-1629Tuber melanosporum39.293e-114 360
LLPS-Asg-0603Ashbya gossypii38.681e-94 310
LLPS-Cog-0336Colletotrichum gloeosporioides38.612e-108 345
LLPS-Sac-0134Saccharomyces cerevisiae38.42e-100 326
LLPS-Ved-0958Verticillium dahliae38.12e-80 268
LLPS-Beb-1528Beauveria bassiana37.931e-105 338
LLPS-Crn-1238Cryptococcus neoformans37.925e-102 329
LLPS-Mao-0666Magnaporthe oryzae37.914e-111 352
LLPS-Ast-0283Aspergillus terreus37.743e-82 273
LLPS-Gag-0969Gaeumannomyces graminis37.722e-106 340
LLPS-Scs-1115Sclerotinia sclerotiorum37.635e-112 355
LLPS-Yal-0723Yarrowia lipolytica37.622e-103 333
LLPS-Fus-1356Fusarium solani37.591e-113 359
LLPS-Zyt-1099Zymoseptoria tritici37.483e-114 360
LLPS-Dos-0866Dothistroma septosporum37.162e-105 337
LLPS-Trr-1590Trichoderma reesei36.794e-103 331
LLPS-Asfu-1561Aspergillus fumigatus36.784e-103 331
LLPS-Trv-1547Trichoderma virens36.767e-105 336
LLPS-Miv-0944Microbotryum violaceum36.76e-110 349
LLPS-Fuo-0756Fusarium oxysporum36.693e-103 331
LLPS-Asni-1554Aspergillus niger36.453e-109 348
LLPS-Nef-1404Neosartorya fischeri36.418e-104 332
LLPS-Asc-1559Aspergillus clavatus36.233e-108 344
LLPS-Scj-0761Schizosaccharomyces japonicus36.124e-101 325
LLPS-Pytr-0825Pyrenophora triticirepentis36.041e-109 348
LLPS-Abg-1724Absidia glauca36.038e-97 314
LLPS-Pyt-1425Pyrenophora teres35.868e-109 346
LLPS-Scc-0037Schizosaccharomyces cryophilus35.832e-95 310
LLPS-Asf-1593Aspergillus flavus35.262e-102 329
LLPS-Aso-1388Aspergillus oryzae35.262e-102 329
LLPS-Kop-0860Komagataella pastoris35.232e-100 325
LLPS-Asn-1306Aspergillus nidulans34.827e-104 333
LLPS-Phn-1588Phaeosphaeria nodorum34.291e-93 306
LLPS-Scp-1610Schizosaccharomyces pombe32.693e-91 299