• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sah-3501
LIMK2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: LIM domain kinase 2
Gene Name: LIMK2
Ensembl Gene: ENSSHAG00000012378.1
Ensembl Protein: ENSSHAP00000014501.1
Organism: Sarcophilus harrisii
Taxa ID: 9305
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     KLSSTRTDTH  GVSLTLISRR  TRTLCARWAS  CSECQDPLTN  WYYEKDGKLY  CHKDYWGKFG  60
61    EFCHGCSLLM  TGPVMVAGEY  KYHPECFACM  SCKVILEDGD  AYALVQHSTL  YCGKCYNEVV  120
121   LTPMFERLST  ESAQDQLPYS  VTLISMPATT  EGKRGFSVAI  DSARSDYATT  VQVKEVSRLH  180
181   ISPDIRNAIH  PGDRILEING  TPVRTLRVEE  VEDVIARTSQ  TLQLLIEHDP  VSQRLDHLRL  240
241   DSRLPPHLKP  VGAPHAQNTL  EVKENLDGTL  RRRSLREPMG  SGVLWGGSEE  RGRRGSSPSL  300
301   PSVCLLPLAS  HSPFLVHGVA  YVIGTLGRKV  THKATGKVMV  MKELIRCDEE  TQKTFLTEVK  360
361   VMRSLDHPNV  LKFIGVLYKD  RKRNLLTESI  EGGTLKDFLR  SVDPFPWQQK  VSFAKGIASG  420
421   MAYLHSMCII  HRDLNSHNCL  IKLDKTVVVA  DFGLSRLIVE  ERKKPSSEKA  STKKRTLRKS  480
481   DRKKRYTVVG  NPYWMAPEML  NGKSYDETVD  VFSFGIVLCE  IIGQVYADPD  CLPRTLDFGL  540
541   NVKLFWEKFV  PTDCPPAFFP  LAAICCKLEP  ESRPPFSKLE  DSFEALSLYL  GELGIPLPSE  600
601   LEELDHEDSW  EPPLGPRSLP  PPPGPPS  627
Nucleotide CDS Sequence (FASTA)
1     AAACTCTCCA  GCACGAGGAC  GGACACTCAT  GGGGTTTCCC  TCACACTGAT  CTCCAGGAGG  60
61    ACGAGGACTC  TGTGTGCACG  GTGGGCCTCG  TGCTCAGAAT  GCCAGGACCC  TCTGACCAAC  120
121   TGGTACTACG  AGAAGGACGG  GAAGCTTTAT  TGCCACAAGG  ATTACTGGGG  GAAGTTTGGG  180
181   GAGTTCTGCC  ATGGCTGCTC  GCTGCTCATG  ACCGGGCCTG  TCATGGTAGC  CGGAGAGTAC  240
241   AAGTATCACC  CAGAATGCTT  TGCCTGCATG  AGCTGCAAGG  TGATCCTTGA  AGATGGAGAT  300
301   GCCTACGCCC  TGGTTCAGCA  TTCCACTCTG  TACTGTGGGA  AGTGCTACAA  TGAGGTGGTG  360
361   CTCACGCCCA  TGTTTGAGAG  GCTGTCCACG  GAGTCTGCCC  AGGACCAGCT  GCCTTACTCC  420
421   GTCACGCTCA  TCTCCATGCC  CGCCACTACC  GAAGGCAAGA  GAGGCTTTTC  CGTGGCCATT  480
481   GACAGTGCCC  GCTCCGACTA  CGCCACCACC  GTCCAAGTGA  AAGAGGTCAG  CCGGCTGCAC  540
541   ATCAGCCCCG  ACATCCGGAA  TGCCATCCAC  CCTGGGGACC  GGATTCTGGA  AATCAATGGC  600
601   ACCCCGGTCC  GAACACTGCG  GGTAGAGGAG  GTAGAGGACG  TGATCGCCAG  GACCAGCCAG  660
661   ACCCTGCAGC  TCTTGATTGA  GCACGACCCT  GTGTCCCAGC  GCCTGGATCA  CCTGCGGCTA  720
721   GACTCCCGGC  TTCCCCCCCA  CCTGAAGCCT  GTTGGGGCCC  CTCATGCCCA  GAACACTCTG  780
781   GAGGTGAAGG  AGAACCTGGA  TGGGACCCTG  CGGAGGCGCT  CTCTCAGAGA  GCCCATGGGG  840
841   AGTGGGGTCC  TGTGGGGTGG  AAGTGAAGAG  AGGGGAAGAA  GAGGCTCCTC  CCCCTCCCTC  900
901   CCCTCTGTCT  GTCTCCTTCC  TCTTGCCTCC  CACTCCCCTT  TTCTGGTTCA  TGGCGTTGCG  960
961   TATGTAATTG  GCACTTTGGG  AAGAAAAGTG  ACACACAAGG  CCACCGGCAA  GGTCATGGTT  1020
1021  ATGAAGGAGT  TAATCCGCTG  CGATGAGGAG  ACCCAGAAGA  CCTTCCTAAC  AGAGGTGAAA  1080
1081  GTTATGAGGA  GCCTGGACCA  TCCCAACGTA  CTCAAGTTTA  TCGGGGTCCT  CTACAAGGAC  1140
1141  AGGAAGCGGA  ACCTGCTGAC  AGAGTCCATC  GAGGGGGGCA  CCCTGAAGGA  CTTTCTGCGC  1200
1201  AGCGTGGACC  CATTTCCCTG  GCAACAGAAG  GTCAGCTTTG  CCAAAGGAAT  TGCTTCTGGG  1260
1261  ATGGCCTATC  TGCATTCCAT  GTGCATCATT  CACCGGGACC  TGAACTCCCA  CAACTGTCTC  1320
1321  ATCAAGCTGG  ACAAGACTGT  CGTGGTGGCC  GACTTCGGCC  TCTCGAGGCT  CATTGTGGAG  1380
1381  GAGAGGAAGA  AGCCGTCCTC  AGAGAAGGCT  TCCACCAAGA  AGCGCACCCT  GCGCAAGAGT  1440
1441  GACCGCAAGA  AGCGCTACAC  GGTGGTGGGG  AACCCCTACT  GGATGGCCCC  CGAGATGCTC  1500
1501  AACGGGAAAA  GCTACGATGA  GACTGTGGAT  GTCTTCTCCT  TCGGAATTGT  TCTCTGTGAG  1560
1561  ATCATTGGGC  AGGTGTACGC  CGACCCCGAC  TGTCTCCCCC  GCACACTGGA  CTTTGGGCTC  1620
1621  AACGTGAAAC  TTTTCTGGGA  GAAGTTTGTT  CCCACAGACT  GTCCCCCCGC  TTTCTTTCCA  1680
1681  CTTGCCGCCA  TCTGCTGCAA  ACTGGAGCCT  GAGAGCAGAC  CCCCGTTCTC  AAAACTGGAA  1740
1741  GATTCCTTTG  AAGCACTTTC  CCTGTACCTG  GGAGAGCTGG  GCATCCCCCT  GCCCTCGGAG  1800
1801  CTGGAGGAGC  TGGACCACGA  GGACTCGTGG  GAACCGCCTC  TGGGACCGAG  AAGCCTGCCG  1860
1861  CCGCCCCCAG  GGCCTCCCAG  C  1881

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mod-1806Monodelphis domestica84.270.01008
LLPS-Urm-2180Ursus maritimus82.910.0 976
LLPS-Ora-2633Ornithorhynchus anatinus82.540.0 974
LLPS-Loa-3879Loxodonta africana82.220.0 966
LLPS-Aim-4031Ailuropoda melanoleuca82.20.0 972
LLPS-Dio-2736Dipodomys ordii81.860.0 972
LLPS-Tut-1774Tursiops truncatus81.850.0 904
LLPS-Myl-3115Myotis lucifugus81.540.0 959
LLPS-Pap-4233Pan paniscus81.370.0 912
LLPS-Fud-3941Fukomys damarensis81.360.0 977
LLPS-Otg-3101Otolemur garnettii81.360.0 964
LLPS-Gog-4746Gorilla gorilla81.230.0 912
LLPS-Caf-3288Canis familiaris81.20.0 976
LLPS-Orc-3809Oryctolagus cuniculus81.20.0 974
LLPS-Pat-2868Pan troglodytes81.120.0 912
LLPS-Hos-2777Homo sapiens81.050.0 908
LLPS-Eqc-4070Equus caballus80.960.0 976
LLPS-Mup-3671Mustela putorius furo80.690.0 972
LLPS-Fec-0920Felis catus80.690.0 969
LLPS-Cas-2657Carlito syrichta80.530.0 977
LLPS-Ict-4224Ictidomys tridecemlineatus80.360.0 969
LLPS-Cap-4312Cavia porcellus80.20.0 968
LLPS-Sus-2295Sus scrofa80.130.0 977
LLPS-Gaga-2641Gallus gallus80.10.0 947
LLPS-Nol-4128Nomascus leucogenys79.930.0 965
LLPS-Meg-2551Meleagris gallopavo79.930.0 946
LLPS-Aon-3355Aotus nancymaae79.770.0 963
LLPS-Caj-2788Callithrix jacchus79.60.0 962
LLPS-Cea-1885Cercocebus atys79.380.0 968
LLPS-Paa-2692Papio anubis79.210.0 966
LLPS-Mal-0493Mandrillus leucophaeus79.210.0 966
LLPS-Rhb-4000Rhinopithecus bieti79.210.0 966
LLPS-Chs-3540Chlorocebus sabaeus79.050.0 965
LLPS-Maf-4303Macaca fascicularis79.050.0 965
LLPS-Mam-0520Macaca mulatta79.050.0 965
LLPS-Man-2741Macaca nemestrina79.050.0 965
LLPS-Bot-1817Bos taurus79.040.0 950
LLPS-Ran-4713Rattus norvegicus78.990.0 961
LLPS-Mum-4757Mus musculus78.830.0 961
LLPS-Anp-2535Anas platyrhynchos77.940.0 948
LLPS-Tag-3590Taeniopygia guttata77.290.0 943
LLPS-Fia-2186Ficedula albicollis76.960.0 939
LLPS-Pes-2940Pelodiscus sinensis76.40.0 905
LLPS-Leo-3207Lepisosteus oculatus67.340.0 771
LLPS-Xim-3187Xiphophorus maculatus66.780.0 754
LLPS-Pof-2776Poecilia formosa66.780.0 757
LLPS-Orn-4071Oreochromis niloticus66.210.0 750
LLPS-Scf-3924Scleropages formosus65.840.0 756
LLPS-Scm-1785Scophthalmus maximus65.530.0 741
LLPS-Icp-1483Ictalurus punctatus65.310.0 756
LLPS-Tar-0337Takifugu rubripes64.920.0 743
LLPS-Poa-3847Pongo abelii64.850.0 723
LLPS-Ten-2615Tetraodon nigroviridis63.910.0 725
LLPS-Dar-4104Danio rerio63.710.0 740
LLPS-Gaa-2056Gasterosteus aculeatus63.560.0 738
LLPS-Orl-3083Oryzias latipes63.180.0 721
LLPS-Lac-3568Latimeria chalumnae60.575e-153 455
LLPS-Xet-1785Xenopus tropicalis57.220.0 613
LLPS-Asm-2451Astyanax mexicanus57.020.0 611
LLPS-Anc-2963Anolis carolinensis54.370.0 570
LLPS-Drm-0992Drosophila melanogaster48.93e-79 278
LLPS-Ova-3064Ovis aries42.442e-39 156
LLPS-Mea-2054Mesocricetus auratus42.343e-42 164
LLPS-Cis-1021Ciona savignyi40.947e-50 179
LLPS-Cii-1568Ciona intestinalis37.812e-111 354
LLPS-Sot-0844Solanum tuberosum35.274e-28 120
LLPS-Hea-2734Helianthus annuus34.355e-27 117
LLPS-Hov-0348Hordeum vulgare34.052e-29 124
LLPS-Mua-2429Musa acuminata33.918e-29 122
LLPS-Ori-0065Oryza indica33.482e-26 117
LLPS-Orb-2327Oryza barthii33.483e-26 117
LLPS-Orr-2001Oryza rufipogon33.483e-26 117
LLPS-Org-1266Oryza glaberrima33.483e-26 117
LLPS-Ors-0939Oryza sativa33.483e-26 117
LLPS-Lep-0717Leersia perrieri33.051e-25 115
LLPS-Prp-2263Prunus persica32.948e-26 116
LLPS-Php-1333Physcomitrella patens32.784e-26 117
LLPS-Sob-2344Sorghum bicolor32.624e-25 114
LLPS-Thc-0086Theobroma cacao32.142e-26 118
LLPS-Glm-1884Glycine max32.137e-26 116
LLPS-Brd-1460Brachypodium distachyon31.742e-29 124
LLPS-Zem-1732Zea mays31.074e-29 123
LLPS-Sol-1189Solanum lycopersicum30.864e-26 117
LLPS-Sem-0236Selaginella moellendorffii30.771e-25 113
LLPS-Sei-2285Setaria italica30.718e-29 122
LLPS-Tra-2921Triticum aestivum30.656e-26 117
LLPS-Viv-2444Vitis vinifera30.585e-25 113
LLPS-Usm-1077Ustilago maydis28.125e-25 114