• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sah-3126
HSPA5

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Heat shock protein family A (Hsp70) member 5
Gene Name: HSPA5
Ensembl Gene: ENSSHAG00000008922.1
Ensembl Protein: ENSSHAP00000010333.1
Organism: Sarcophilus harrisii
Taxa ID: 9305
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, PML nuclear body, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSSHAT00000010423.1ENSSHAP00000010333.1
UniProtG3W4H8, G3W4H8_SARHA
GeneBankAEFK01020457

▼ SEQUENCE

Protein Sequence (FASTA)
1     RMRRSLVAAA  LLLLVAMGAR  ADEDDKKEDV  GTVVGIDLGT  TYSCVGVFKN  GRVEIIANDQ  60
61    GNRITPSYVA  FTPEGERLIG  DAAKNQLTSN  PENTVFDAKR  LIGRTWNDPS  VQQDIKYLPF  120
121   KVVEKKTKPY  IQVDVGGGQT  KTFAPEEISA  MVLTKMKETA  EAYLGKKVTH  AVVTVPAYFN  180
181   DAQRQATKDA  GTIAGLNVMR  IINEPTAAAI  AYGLDKREGE  KNILVFDLGG  GTFDVSLLTI  240
241   DNGVFEVVAT  NGDTHLGGED  FDQRVMEHFI  KLYKKKTGKD  VRKDNRAVQK  LRREVEKAKR  300
301   ALSSQHQARI  EIESFFEGED  FSETLTRAKF  EELNMDLFRS  TMKPVQKVLE  DSDLKKSDID  360
361   EIVLVGGSTR  IPKIQLLVKE  FFNGKEPSRG  INPDEAVAYG  AAVQAGVLSG  DQDTGDLVLL  420
421   DVCPLTLGIE  TVGGVMTKLI  PRNTVVPTKK  SQIFSTASDN  QPTVTIKVYE  GERPLTKDNH  480
481   LLGTFDLTGI  PPAPRGVPQI  EVTFEIDVNG  ILRVTAEDKG  TGNKNKITIT  NDQNRLTPEE  540
541   IERMVNDAEK  FAEEDKKLKE  RIDSRNELES  YAYSLKNQIG  DKEKLGGKLS  SEDKEIVEKA  600
601   VEEKIEWLES  HQDAEIEDFK  AKKKELEEIV  QPIVSKLYGG  AGPPPGSEET  GEKDEL  656
Nucleotide CDS Sequence (FASTA)
1     AGGATGAGGC  GCTCGCTCGT  GGCGGCCGCT  CTGCTGCTCC  TGGTGGCCAT  GGGGGCTCGG  60
61    GCTGACGAAG  ACGACAAGAA  GGAGGACGTG  GGCACGGTGG  TGGGCATCGA  TCTGGGCACC  120
121   ACTTACTCGT  GTGTTGGCGT  GTTTAAGAAT  GGTCGAGTGG  AAATTATTGC  CAATGATCAG  180
181   GGCAACCGAA  TCACACCTTC  CTATGTGGCT  TTCACCCCAG  AAGGAGAGCG  GCTCATTGGT  240
241   GATGCCGCCA  AAAACCAGCT  TACCTCAAAC  CCCGAGAACA  CAGTCTTTGA  CGCTAAGCGG  300
301   CTGATTGGCC  GAACGTGGAA  TGACCCTTCA  GTGCAGCAGG  ACATTAAATA  CCTGCCTTTC  360
361   AAGGTGGTTG  AAAAGAAGAC  CAAACCATAC  ATTCAGGTAG  ATGTTGGAGG  TGGACAAACA  420
421   AAGACATTTG  CTCCTGAAGA  AATTTCTGCT  ATGGTCCTGA  CTAAGATGAA  GGAAACAGCT  480
481   GAGGCATATC  TAGGCAAAAA  GGTTACTCAT  GCAGTTGTTA  CCGTTCCTGC  CTATTTCAAT  540
541   GATGCCCAGC  GTCAAGCAAC  CAAAGATGCT  GGTACTATTG  CTGGTCTTAA  TGTCATGAGG  600
601   ATAATCAATG  AACCTACTGC  AGCTGCTATT  GCCTACGGCC  TAGACAAGAG  GGAGGGAGAA  660
661   AAGAACATCC  TTGTGTTTGA  TCTGGGTGGT  GGCACCTTTG  ATGTGTCCTT  GCTCACCATT  720
721   GACAATGGAG  TGTTTGAAGT  GGTGGCCACA  AATGGTGACA  CTCATTTGGG  TGGAGAAGAC  780
781   TTCGATCAGC  GAGTCATGGA  GCACTTTATT  AAGTTGTACA  AAAAGAAAAC  TGGAAAAGAT  840
841   GTGAGGAAAG  ACAACAGAGC  TGTGCAGAAA  CTTCGAAGGG  AAGTTGAAAA  GGCTAAACGG  900
901   GCCTTGTCCT  CTCAACATCA  GGCTAGAATT  GAAATTGAAT  CTTTCTTTGA  AGGTGAAGAT  960
961   TTCTCTGAGA  CACTCACTCG  TGCTAAGTTT  GAAGAACTAA  ACATGGATTT  GTTCCGGTCT  1020
1021  ACAATGAAGC  CTGTCCAGAA  AGTACTAGAG  GATTCAGACT  TGAAGAAGTC  TGATATTGAT  1080
1081  GAAATTGTTC  TTGTTGGGGG  CTCTACTCGG  ATCCCTAAAA  TACAACTATT  GGTGAAAGAG  1140
1141  TTCTTCAATG  GCAAAGAGCC  TTCCCGGGGT  ATTAATCCAG  ATGAAGCTGT  TGCTTATGGT  1200
1201  GCTGCTGTCC  AGGCTGGTGT  ATTGTCTGGT  GATCAAGATA  CTGGTGATCT  GGTGCTTCTT  1260
1261  GATGTGTGTC  CCCTTACACT  TGGCATTGAA  ACTGTTGGTG  GTGTCATGAC  CAAATTAATC  1320
1321  CCAAGAAATA  CTGTTGTGCC  CACCAAGAAA  TCTCAGATCT  TTTCTACTGC  TTCTGATAAT  1380
1381  CAGCCAACTG  TCACTATCAA  AGTCTATGAA  GGTGAGCGAC  CTCTGACCAA  GGATAATCAC  1440
1441  CTCCTGGGAA  CATTTGACTT  GACGGGAATT  CCTCCTGCTC  CTCGAGGGGT  CCCTCAGATT  1500
1501  GAAGTCACCT  TTGAAATAGA  TGTGAATGGT  ATTCTTCGGG  TCACCGCTGA  AGACAAGGGC  1560
1561  ACCGGGAACA  AGAATAAGAT  CACAATCACC  AATGACCAAA  ACCGTCTTAC  ACCAGAAGAG  1620
1621  ATTGAGAGGA  TGGTAAACGA  TGCTGAGAAG  TTTGCTGAGG  AGGACAAGAA  GCTTAAAGAA  1680
1681  CGTATTGATA  GCCGAAATGA  GCTGGAGAGT  TATGCCTATT  CACTAAAGAA  CCAGATTGGT  1740
1741  GATAAGGAAA  AGCTGGGTGG  AAAGCTCTCC  TCTGAAGACA  AGGAGATTGT  AGAAAAAGCA  1800
1801  GTGGAAGAAA  AAATTGAGTG  GCTTGAGAGT  CACCAAGATG  CAGAAATTGA  AGATTTCAAA  1860
1861  GCAAAAAAGA  AGGAACTTGA  AGAGATTGTC  CAGCCTATTG  TTAGTAAGCT  ATATGGTGGT  1920
1921  GCAGGCCCTC  CCCCAGGGAG  CGAAGAAACG  GGAGAAAAAG  ATGAGTTGTA  G  1971

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mod-1244Monodelphis domestica99.690.01221
LLPS-Meg-1019Meleagris gallopavo99.070.0 839
LLPS-Myl-3612Myotis lucifugus98.390.01187
LLPS-Eqc-0511Equus caballus98.120.0 928
LLPS-Anp-1043Anas platyrhynchos97.880.01156
LLPS-Ora-0768Ornithorhynchus anatinus97.810.01203
LLPS-Mea-0724Mesocricetus auratus97.650.01206
LLPS-Otg-3831Otolemur garnettii97.640.01204
LLPS-Bot-3329Bos taurus97.50.01207
LLPS-Mum-0261Mus musculus97.490.01205
LLPS-Gog-2076Gorilla gorilla97.480.01202
LLPS-Aon-2439Aotus nancymaae97.480.01201
LLPS-Cea-0975Cercocebus atys97.480.01202
LLPS-Maf-0390Macaca fascicularis97.480.01202
LLPS-Chs-0675Chlorocebus sabaeus97.480.01202
LLPS-Mal-1104Mandrillus leucophaeus97.480.01202
LLPS-Man-0532Macaca nemestrina97.480.01202
LLPS-Hos-0375Homo sapiens97.480.01202
LLPS-Pap-1942Pan paniscus97.480.01202
LLPS-Pat-3099Pan troglodytes97.480.01202
LLPS-Cas-0070Carlito syrichta97.480.01202
LLPS-Mam-0397Macaca mulatta97.480.01202
LLPS-Poa-1791Pongo abelii97.480.01202
LLPS-Dio-2385Dipodomys ordii97.350.01210
LLPS-Ova-0891Ovis aries97.340.01204
LLPS-Ran-3206Rattus norvegicus97.340.01202
LLPS-Gaga-1387Gallus gallus97.340.01203
LLPS-Caf-1606Canis familiaris97.340.01202
LLPS-Fud-1862Fukomys damarensis97.330.01201
LLPS-Aim-3020Ailuropoda melanoleuca97.330.01198
LLPS-Mup-2741Mustela putorius furo97.330.01199
LLPS-Fia-1571Ficedula albicollis97.330.01202
LLPS-Urm-0428Ursus maritimus97.330.01199
LLPS-Fec-0789Felis catus97.330.01199
LLPS-Cap-1431Cavia porcellus97.330.01202
LLPS-Pes-1097Pelodiscus sinensis97.230.01155
LLPS-Sus-0432Sus scrofa97.180.01202
LLPS-Tut-1066Tursiops truncatus97.180.01194
LLPS-Loa-0752Loxodonta africana97.170.01199
LLPS-Ict-1593Ictidomys tridecemlineatus97.170.01200
LLPS-Tag-2254Taeniopygia guttata97.030.01205
LLPS-Nol-2775Nomascus leucogenys97.010.01193
LLPS-Orc-0520Oryctolagus cuniculus96.70.01192
LLPS-Anc-1615Anolis carolinensis96.470.01172
LLPS-Leo-1488Lepisosteus oculatus95.790.01150
LLPS-Xet-2451Xenopus tropicalis95.770.01177
LLPS-Lac-3426Latimeria chalumnae95.60.01174
LLPS-Gaa-0292Gasterosteus aculeatus94.510.01144
LLPS-Scf-0530Scleropages formosus94.010.01160
LLPS-Dar-1271Danio rerio93.710.01157
LLPS-Xim-1086Xiphophorus maculatus93.420.01160
LLPS-Asm-1719Astyanax mexicanus93.270.01149
LLPS-Icp-2123Ictalurus punctatus93.260.01150
LLPS-Pof-2009Poecilia formosa93.10.01159
LLPS-Scm-1039Scophthalmus maximus92.960.01148
LLPS-Orl-0864Oryzias latipes92.630.01157
LLPS-Tar-1694Takifugu rubripes92.630.01144
LLPS-Ten-1400Tetraodon nigroviridis92.610.01137
LLPS-Caj-0497Callithrix jacchus90.920.01105
LLPS-Cis-0701Ciona savignyi83.250.0 984
LLPS-Cii-0730Ciona intestinalis82.950.0 997
LLPS-Orn-0393Oreochromis niloticus82.490.01013
LLPS-Drm-0842Drosophila melanogaster82.380.01008
LLPS-Paa-1109Papio anubis80.590.0 849
LLPS-Cae-1273Caenorhabditis elegans79.840.0 984
LLPS-Rhb-1308Rhinopithecus bieti76.880.0 880
LLPS-Php-1011Physcomitrella patens73.160.0 869
LLPS-Glm-1559Glycine max73.00.0 883
LLPS-Gor-1333Gossypium raimondii72.610.0 891
LLPS-Mae-0910Manihot esculenta72.570.0 890
LLPS-Via-0971Vigna angularis72.50.0 862
LLPS-Thc-0198Theobroma cacao72.250.0 884
LLPS-Amt-1551Amborella trichopoda72.180.0 865
LLPS-Coc-0528Corchorus capsularis72.090.0 886
LLPS-Sol-0215Solanum lycopersicum72.050.0 882
LLPS-Cus-0312Cucumis sativus71.970.0 887
LLPS-Lep-0278Leersia perrieri71.770.0 851
LLPS-Tru-1026Triticum urartu71.770.0 865
LLPS-Phv-1238Phaseolus vulgaris71.730.0 865
LLPS-Nia-0007Nicotiana attenuata71.660.0 889
LLPS-Met-0071Medicago truncatula71.520.0 848
LLPS-Sob-2131Sorghum bicolor71.480.0 849
LLPS-Osl-0295Ostreococcus lucimarinus71.470.0 840
LLPS-Orbr-0819Oryza brachyantha71.450.0 847
LLPS-Zem-0077Zea mays71.450.0 863
LLPS-Sem-2037Selaginella moellendorffii71.410.0 859
LLPS-Pot-2698Populus trichocarpa71.360.0 863
LLPS-Orp-1090Oryza punctata71.290.0 846
LLPS-Tra-2794Triticum aestivum71.270.0 872
LLPS-Mua-0203Musa acuminata71.190.0 860
LLPS-Brr-0887Brassica rapa71.190.0 858
LLPS-Art-1345Arabidopsis thaliana71.190.0 859
LLPS-Bro-1964Brassica oleracea71.190.0 858
LLPS-Viv-0482Vitis vinifera71.180.0 876
LLPS-Hea-1266Helianthus annuus71.140.0 881
LLPS-Orni-0512Oryza nivara71.130.0 843
LLPS-Orb-0598Oryza barthii71.130.0 843
LLPS-Ori-0672Oryza indica71.130.0 843
LLPS-Orgl-0486Oryza glumaepatula71.130.0 843
LLPS-Ors-0923Oryza sativa71.130.0 843
LLPS-Org-0958Oryza glaberrima71.130.0 843
LLPS-Orr-1968Oryza rufipogon71.130.0 843
LLPS-Orm-1109Oryza meridionalis71.130.0 843
LLPS-Prp-0027Prunus persica71.020.0 874
LLPS-Sot-1340Solanum tuberosum70.950.0 884
LLPS-Arl-0174Arabidopsis lyrata70.630.0 872
LLPS-Crn-1338Cryptococcus neoformans70.570.0 844
LLPS-Sei-0902Setaria italica70.470.0 869
LLPS-Mao-0061Magnaporthe oryzae70.380.0 857
LLPS-Dac-0841Daucus carota70.250.0 865
LLPS-Map-0493Magnaporthe poae69.730.0 856
LLPS-Brd-0012Brachypodium distachyon69.720.0 866
LLPS-Scp-0439Schizosaccharomyces pombe69.710.0 829
LLPS-Beb-0588Beauveria bassiana69.570.0 849
LLPS-Asni-1193Aspergillus niger69.540.0 842
LLPS-Nec-0630Neurospora crassa69.540.0 844
LLPS-Trr-0657Trichoderma reesei69.530.0 862
LLPS-Fuo-1509Fusarium oxysporum69.430.0 838
LLPS-Gag-1465Gaeumannomyces graminis69.410.0 849
LLPS-Scj-0468Schizosaccharomyces japonicus69.290.0 833
LLPS-Nef-1194Neosartorya fischeri69.170.0 841
LLPS-Asfu-0766Aspergillus fumigatus69.010.0 840
LLPS-Sac-0909Saccharomyces cerevisiae68.980.0 815
LLPS-Yal-0780Yarrowia lipolytica68.90.0 820
LLPS-Trv-1559Trichoderma virens68.890.0 846
LLPS-Brn-1201Brassica napus68.870.0 848
LLPS-Spr-0927Sporisorium reilianum68.850.0 845
LLPS-Ved-1322Verticillium dahliae68.790.0 833
LLPS-Asc-0134Aspergillus clavatus68.750.0 833
LLPS-Fus-1024Fusarium solani68.70.0 850
LLPS-Cogr-0841Colletotrichum graminicola68.570.0 833
LLPS-Abg-0084Absidia glauca68.540.0 843
LLPS-Fuv-0938Fusarium verticillioides68.40.0 845
LLPS-Ast-1487Aspergillus terreus68.390.0 850
LLPS-Cog-0961Colletotrichum gloeosporioides68.30.0 826
LLPS-Coo-0077Colletotrichum orbiculare68.250.0 822
LLPS-Mel-0277Melampsora laricipopulina68.160.0 844
LLPS-Scs-0152Sclerotinia sclerotiorum68.080.0 840
LLPS-Asf-0636Aspergillus flavus68.080.0 831
LLPS-Aso-0276Aspergillus oryzae68.080.0 831
LLPS-Asn-0213Aspergillus nidulans68.020.0 827
LLPS-Cym-0933Cyanidioschyzon merolae67.80.0 795
LLPS-Hov-1127Hordeum vulgare67.780.0 850
LLPS-Chr-0978Chlamydomonas reinhardtii67.770.0 828
LLPS-Pyt-1329Pyrenophora teres67.540.0 791
LLPS-Tum-1076Tuber melanosporum67.530.0 828
LLPS-Gas-0365Galdieria sulphuraria67.30.0 830
LLPS-Asg-0498Ashbya gossypii67.160.0 788
LLPS-Blg-0194Blumeria graminis67.140.0 824
LLPS-Scc-0008Schizosaccharomyces cryophilus67.090.0 800
LLPS-Miv-1427Microbotryum violaceum66.560.0 819
LLPS-Pug-0721Puccinia graminis66.510.0 850
LLPS-Chc-0171Chondrus crispus66.120.0 793
LLPS-Dos-0310Dothistroma septosporum66.090.0 802
LLPS-Lem-0544Leptosphaeria maculans65.530.0 796
LLPS-Usm-1346Ustilago maydis65.020.0 787
LLPS-Zyt-0747Zymoseptoria tritici64.960.0 804
LLPS-Put-0099Puccinia triticina64.490.0 814