• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Rhb-2451
STAT5A

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Signal transducer and activator of transcription
Gene Name: STAT5A
Ensembl Gene: ENSRBIG00000006369.1
Ensembl Protein: ENSRBIP00000001246.1
Organism: Rhinopithecus bieti
Taxa ID: 61621
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAGWIQAQQL  QGDALRQMQV  LYGQHFPIEV  RHYLAQWIES  QPWDAIDLDN  PQDRAQATQL  60
61    LEGLVQELQK  KAEHQVGEDG  FLLKIKLGHY  ATQLQNTYDR  CPMELVRCIR  HILYNEQRLV  120
121   REANNCSSPA  GILVDAMSQK  HLQINQTFEE  LRLVTQDTEN  ELKKLQQTQE  YFIIQYQESL  180
181   RIQGEARWRH  SVHPEGGSEE  RSMGSYRGGL  GLEVFWLNQA  GRGGPSRVGL  LECEKLAEII  240
241   WQNRQQIRRA  EHLCQQLPIP  GPVEEMLAEV  NATITDIISA  LVTSTFIIEK  QPPQVLKTQT  300
301   KFAATVRLLV  GGKLNVHMNP  PQVKATIISE  QQAKSLLKNE  NTRNECSGEI  LNNCCVMEYH  360
361   QATGTLSAHF  RNMSLKRIKR  ADRRGAESVT  EEKFTVLFES  QFSVGSNELV  FQVKTLSLPV  420
421   VVIVHGSQDH  NATATVLWDN  AFAEPGRVPF  AVPDKVLWPQ  LCEALNMKFK  AEVQSNRGLT  480
481   KENLVFLAQK  LFNNSSSHLE  DYSSLSVSWS  QFNRENLPGW  NYTFWQWFDG  VMEVLKKHHK  540
541   PHWNDGAILG  FVNKQQAHDL  LINKPDGTFL  LRFSDSEIGG  ITIAWKFDSP  ERNLWNLKPF  600
601   TTRDFSIRSL  ADRLGDLSYL  IYVFPDRPKD  EVFSKYYTPV  LAKAVDGYVK  PQIKQVVPEW  660
661   LWPSFCLFPP  SPDPASHPDP  GPSFLPDPVL  DQDGEFDLDE  TMDVARHVEE  LLRRPMDSLD  720
721   SRLSPPAGLF  TSARGSLS  738
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGGCT  GGATCCAGGC  CCAGCAGCTG  CAGGGAGATG  CGCTGCGCCA  GATGCAGGTG  60
61    CTGTACGGCC  AGCACTTCCC  CATCGAGGTC  CGTCACTACT  TGGCCCAGTG  GATTGAGAGC  120
121   CAGCCATGGG  ATGCCATTGA  CTTGGACAAT  CCCCAGGACA  GAGCCCAAGC  CACCCAGCTC  180
181   CTGGAGGGCC  TGGTGCAGGA  GCTGCAGAAG  AAGGCGGAGC  ACCAGGTGGG  GGAAGATGGG  240
241   TTTTTACTGA  AGATCAAGCT  GGGGCACTAC  GCCACACAGC  TCCAGAACAC  GTATGACCGC  300
301   TGCCCCATGG  AGCTGGTCCG  CTGCATCCGG  CACATTCTGT  ACAATGAACA  GAGGCTGGTC  360
361   CGAGAAGCCA  ACAACTGCAG  TTCTCCGGCT  GGGATCCTGG  TTGACGCCAT  GTCCCAGAAA  420
421   CACCTTCAGA  TCAACCAGAC  ATTTGAGGAG  CTGCGACTGG  TCACGCAGGA  CACAGAGAAT  480
481   GAGCTGAAGA  AGCTGCAGCA  GACTCAGGAA  TACTTCATCA  TCCAGTACCA  GGAGAGCCTG  540
541   AGGATCCAAG  GTGAGGCGCG  GTGGAGGCAC  AGTGTGCATC  CTGAGGGTGG  GAGTGAGGAA  600
601   CGTTCTATGG  GCTCCTACAG  GGGAGGACTT  GGATTGGAAG  TCTTCTGGTT  GAACCAGGCT  660
661   GGGAGAGGTG  GGCCTTCTAG  AGTGGGTCTT  CTTGAGTGTG  AGAAGTTGGC  TGAGATCATC  720
721   TGGCAGAACC  GGCAGCAGAT  CCGCAGGGCT  GAGCACCTCT  GCCAGCAGCT  GCCCATCCCT  780
781   GGCCCAGTGG  AGGAGATGCT  GGCTGAGGTC  AACGCCACCA  TCACGGACAT  CATCTCAGCC  840
841   CTGGTGACCA  GCACATTCAT  CATTGAGAAG  CAGCCTCCTC  AGGTCCTGAA  GACCCAGACC  900
901   AAGTTTGCAG  CCACCGTGCG  CCTGCTGGTG  GGCGGGAAGC  TGAACGTGCA  CATGAACCCG  960
961   CCCCAGGTGA  AGGCCACCAT  CATCAGTGAG  CAGCAGGCCA  AGTCTCTGCT  CAAGAACGAG  1020
1021  AACACCCGCA  ACGAGTGCAG  TGGTGAGATC  CTGAACAACT  GCTGCGTGAT  GGAGTACCAC  1080
1081  CAAGCCACGG  GCACCCTCAG  CGCCCACTTC  AGGAACATGT  CACTGAAGAG  GATCAAGCGT  1140
1141  GCTGACCGGC  GGGGTGCAGA  GTCCGTGACA  GAGGAGAAGT  TCACAGTCCT  GTTTGAGTCT  1200
1201  CAGTTCAGTG  TTGGCAGCAA  TGAGCTTGTG  TTCCAGGTGA  AGGGCAGGGT  GCCATTTGCC  1260
1261  GTGCCTGACA  AAGTGCTGTG  GCCGCAGCTG  TGTGAGGCGC  TGAACATGAA  ATTCAAGGCC  1320
1321  GAAGTGCAGA  GCAACCGGGG  CCTGACCAAG  GAGAACCTTG  TGTTCCTGGC  GCAGAAACTG  1380
1381  TTCAACAACA  GCAGCAGCCA  CCTGGAGGAC  TACAGCAGCC  TGTCCGTGTC  CTGGTCCCAG  1440
1441  TTCAACAGGG  AGAACTTGCC  GGGCTGGAAC  TACACCTTCT  GGCAGTGGTT  TGACGGGGTG  1500
1501  ATGGAGGTGT  TGAAGAAGCA  CCACAAGCCC  CACTGGAATG  ATGGGGCCAT  CCTAGGTTTT  1560
1561  GTGAATAAGC  AACAGGCCCA  TGACCTGCTC  ATCAACAAGC  CCGATGGGAC  CTTCTTGTTG  1620
1621  CGCTTTAGTG  ACTCAGAAAT  TGGGGGTATC  ACCATCGCCT  GGAAATTTGA  CTCCCCGGAA  1680
1681  CGCAACCTGT  GGAACCTGAA  ACCATTCACC  ACACGGGATT  TCTCCATCAG  GTCCCTGGCT  1740
1741  GACCGGCTGG  GGGACCTGAG  CTATCTCATC  TATGTGTTTC  CTGACCGCCC  CAAGGATGAG  1800
1801  GTCTTCTCCA  AGTACTACAC  TCCAGTGCTG  GCTAAAGCTG  TTGATGGATA  CGTGAAGCCA  1860
1861  CAGATCAAGC  AAGTGGTCCC  TGAGTGGCTC  TGGCCCTCCT  TCTGCCTCTT  TCCTCCTTCC  1920
1921  CCAGACCCTG  CCTCCCATCC  CGATCCTGGA  CCCAGCTTTC  TCCCTGACCC  TGTCCTTGAC  1980
1981  CAGGATGGAG  AATTCGACCT  GGATGAGACC  ATGGATGTGG  CCAGGCACGT  GGAGGAACTC  2040
2041  TTACGCCGAC  CGATGGACAG  TCTTGACTCC  CGCCTCTCGC  CCCCTGCCGG  TCTTTTCACC  2100
2101  TCTGCCAGAG  GCTCCCTCTC  ATGA  2124

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Nol-1799Nomascus leucogenys98.954e-121 369
LLPS-Aon-3604Aotus nancymaae97.442e-123 375
LLPS-Mea-3394Mesocricetus auratus95.384e-122 372
LLPS-Aim-2106Ailuropoda melanoleuca91.941e-107 352
LLPS-Mal-3468Mandrillus leucophaeus91.355e-108 349
LLPS-Gog-2767Gorilla gorilla91.090.0 725
LLPS-Pat-4656Pan troglodytes86.460.01305
LLPS-Caj-1705Callithrix jacchus85.770.0 855
LLPS-Paa-3749Papio anubis85.160.01311
LLPS-Mam-4220Macaca mulatta85.160.01308
LLPS-Poa-3028Pongo abelii85.030.01302
LLPS-Man-1785Macaca nemestrina85.030.01310
LLPS-Maf-1062Macaca fascicularis84.910.01307
LLPS-Cea-3936Cercocebus atys84.910.01308
LLPS-Hos-2872Homo sapiens84.910.01303
LLPS-Pap-4608Pan paniscus84.910.01305
LLPS-Mum-5010Mus musculus84.820.01167
LLPS-Ict-2235Ictidomys tridecemlineatus84.80.01290
LLPS-Chs-4022Chlorocebus sabaeus84.590.01300
LLPS-Dio-4235Dipodomys ordii83.750.01287
LLPS-Ran-0857Rattus norvegicus83.50.01291
LLPS-Caf-3927Canis familiaris83.270.01285
LLPS-Sus-3665Sus scrofa83.00.01281
LLPS-Ova-0998Ovis aries82.810.01258
LLPS-Tut-2315Tursiops truncatus82.790.01287
LLPS-Bot-4420Bos taurus82.750.01277
LLPS-Otg-4748Otolemur garnettii82.750.01278
LLPS-Eqc-0341Equus caballus82.630.01203
LLPS-Mup-3668Mustela putorius furo82.440.01278
LLPS-Myl-2226Myotis lucifugus82.330.01271
LLPS-Orc-2829Oryctolagus cuniculus82.290.01280
LLPS-Fec-2825Felis catus81.570.01258
LLPS-Cas-1006Carlito syrichta78.990.01010
LLPS-Urm-2194Ursus maritimus78.910.01200
LLPS-Mod-2576Monodelphis domestica78.590.01169
LLPS-Cap-1424Cavia porcellus77.490.01195
LLPS-Scf-4085Scleropages formosus69.490.01056
LLPS-Scm-0986Scophthalmus maximus68.520.01035
LLPS-Tag-2767Taeniopygia guttata48.295e-123 381
LLPS-Gaa-0245Gasterosteus aculeatus47.955e-114 367
LLPS-Loa-4562Loxodonta africana40.322e-136 430
LLPS-Fud-3416Fukomys damarensis39.712e-133 422
LLPS-Sah-3391Sarcophilus harrisii39.162e-130 415
LLPS-Anc-3759Anolis carolinensis39.051e-127 402
LLPS-Fia-2034Ficedula albicollis38.993e-129 411
LLPS-Xet-3306Xenopus tropicalis38.916e-122 390
LLPS-Dar-1659Danio rerio38.883e-131 414
LLPS-Asm-2364Astyanax mexicanus38.42e-120 383
LLPS-Orl-4108Oryzias latipes37.84e-129 407
LLPS-Xim-1019Xiphophorus maculatus37.112e-120 384
LLPS-Icp-2517Ictalurus punctatus36.952e-128 407
LLPS-Orn-4099Oreochromis niloticus36.624e-129 408
LLPS-Pof-0229Poecilia formosa36.583e-120 384
LLPS-Leo-2471Lepisosteus oculatus30.661e-73 260
LLPS-Tar-2090Takifugu rubripes30.524e-75 265
LLPS-Gaga-1090Gallus gallus30.132e-69 248
LLPS-Meg-1678Meleagris gallopavo30.132e-69 248
LLPS-Ten-0724Tetraodon nigroviridis26.582e-58 217