• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Leo-2471

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Signal transducer and activator of transcription
Ensembl Gene: ENSLOCG00000012514.1
Ensembl Protein: ENSLOCP00000015422.1
Organism: Lepisosteus oculatus
Taxa ID: 7918
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Nuclear pore complex, Nuclear speckle, PML nuclear body, Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAQWNQLQQL  DPRYLEQLYH  LYSDSFPMEL  RQFLAPWIES  QDWAYAANKE  SHATLVFHNL  60
61    LGEIDQQYSR  FLQENNVLYQ  HNLRRIKQHL  QSKYLEKPME  IARIVARCLW  EENRLLQTAT  120
121   TTAQDGQASH  PTGTVVTEKQ  QILEHNLQDV  RKRVQDMEQK  MKMLENLQDD  FDFNYKTLKS  180
181   QGEISQDLNG  NSQAAATRQK  MAQLEQMLTA  LDQLRRQIVT  EMAGLLSAMD  FVQKNLTDEE  240
241   LADWKRRQQI  ACIGGPPNIC  LDRLETWITS  LAESQLQIRQ  QIKKLEELQQ  KVSYKGDPIV  300
301   QHRPALEEKI  VDIFRNLMKS  AFVVERQPCM  PMHPDRPLVI  KTGVQFTTKV  RLLVKFPELN  360
361   YQLKIKVCID  KESGDVAALR  GSRKFNILGT  NTKVMNMEES  NNGSLSAEFK  HLTLREQRCG  420
421   NGGRANSDAS  LIVTEELHLI  TFETEVYHQG  LKIDLETHSL  PVVVISNICQ  MPNAWASILW  480
481   YNMLTNHPKN  VNFFTKPPVA  TWDQVAEVLS  WQFSSTTKRG  LTIEQLTTLA  EKLLGPCVNY  540
541   SGCQITWAKF  CKENMAGKGF  SFWVWLDNII  DLVKKYILAL  WNEGYIMGFI  SKERERAILS  600
601   TKPPGTFLLR  FSESSKEGGI  TFTWVEKDIS  GKTQIQSVEP  YTKQQLNSMS  FAEIIMGYKI  660
661   MDATNILVSP  LVYLFPEIPK  EEAFGKYCRT  ENTEQPDFTD  PGSTVPYLKT  KFICVTPSPS  720
721   VFMDMPDSEL  LANGYSGTNS  GNTSDLFPMS  PRTLDSLMHN  EVQEPNPGGG  PLESLTLDME  780
781   FTSEAASPM  789
Nucleotide CDS Sequence (FASTA)
1     ATGGCCCAGT  GGAATCAGTT  GCAGCAGCTG  GACCCCAGAT  ACCTGGAGCA  GCTCTACCAC  60
61    CTCTACAGCG  ACAGCTTCCC  CATGGAGCTG  CGGCAGTTCC  TCGCCCCCTG  GATCGAGAGT  120
121   CAGGACTGGG  CCTACGCTGC  CAACAAAGAA  TCGCACGCCA  CGCTGGTTTT  CCACAACCTC  180
181   CTGGGGGAGA  TCGACCAGCA  GTACAGCCGC  TTCCTCCAGG  AGAACAACGT  GCTCTACCAG  240
241   CACAACCTGC  GCAGGATCAA  GCAGCACTTG  CAGAGCAAGT  ACCTGGAAAA  GCCCATGGAG  300
301   ATCGCGAGGA  TAGTGGCCCG  ATGCCTGTGG  GAAGAGAATC  GATTGCTGCA  GACTGCTACA  360
361   ACCACGGCCC  AGGATGGGCA  GGCGTCTCAC  CCCACGGGCA  CGGTTGTGAC  GGAGAAGCAG  420
421   CAGATTCTGG  AGCACAACCT  GCAGGACGTG  AGGAAAAGAG  TGCAGGATAT  GGAACAGAAG  480
481   ATGAAAATGC  TGGAAAACCT  GCAGGATGAC  TTTGACTTTA  ACTACAAGAC  TCTGAAAAGC  540
541   CAAGGAGAAA  TCTCCCAGGA  TCTGAACGGG  AACAGTCAGG  CAGCAGCAAC  GAGACAGAAA  600
601   ATGGCACAGC  TGGAGCAGAT  GTTGACAGCT  TTGGATCAGC  TCCGAAGGCA  AATCGTGACC  660
661   GAGATGGCGG  GGTTGCTGTC  GGCCATGGAC  TTTGTGCAGA  AGAACCTGAC  GGATGAGGAA  720
721   CTGGCGGACT  GGAAGAGGCG  GCAGCAGATC  GCCTGCATCG  GGGGACCCCC  CAACATCTGC  780
781   CTGGACCGCC  TGGAGACCTG  GATTACCTCT  CTGGCCGAGT  CCCAGCTGCA  GATCAGACAG  840
841   CAGATCAAGA  AGCTGGAGGA  GCTGCAGCAG  AAGGTGTCCT  ACAAGGGCGA  CCCCATCGTC  900
901   CAGCACCGGC  CTGCCCTGGA  GGAGAAGATA  GTGGACATCT  TCAGGAACCT  CATGAAAAGT  960
961   GCCTTTGTGG  TGGAGCGACA  GCCATGTATG  CCTATGCACC  CCGATAGGCC  TCTGGTCATT  1020
1021  AAGACAGGGG  TGCAGTTCAC  TACCAAGGTC  AGGTTACTGG  TGAAATTTCC  CGAGCTGAAT  1080
1081  TATCAACTGA  AGATTAAAGT  CTGCATCGAC  AAGGAATCGG  GGGATGTGGC  AGCATTGAGA  1140
1141  GGTTCCCGCA  AGTTCAACAT  CTTGGGTACA  AACACGAAAG  TGATGAACAT  GGAGGAGTCC  1200
1201  AATAACGGCA  GCCTCTCCGC  TGAGTTCAAA  CACCTGACCC  TGAGAGAGCA  GCGGTGTGGG  1260
1261  AATGGAGGCC  GGGCGAACAG  TGATGCCTCT  CTGATCGTGA  CCGAGGAGCT  GCATCTCATC  1320
1321  ACCTTCGAGA  CTGAGGTCTA  CCACCAGGGG  CTGAAGATCG  ACCTGGAGAC  GCATTCTTTG  1380
1381  CCTGTGGTCG  TCATCTCCAA  CATCTGCCAG  ATGCCCAACG  CCTGGGCGTC  CATCCTGTGG  1440
1441  TACAACATGC  TGACCAATCA  CCCTAAGAAC  GTCAACTTCT  TCACCAAGCC  CCCCGTGGCC  1500
1501  ACGTGGGACC  AGGTGGCCGA  GGTGCTGAGC  TGGCAGTTCT  CCTCCACGAC  CAAGCGGGGG  1560
1561  CTGACCATCG  AGCAGCTGAC  CACACTGGCG  GAGAAGCTGC  TGGGACCTTG  TGTGAACTAC  1620
1621  TCTGGGTGTC  AGATCACATG  GGCAAAGTTC  TGCAAGGAGA  ATATGGCAGG  GAAAGGGTTT  1680
1681  TCATTCTGGG  TGTGGCTGGA  CAATATCATC  GACCTGGTGA  AGAAGTACAT  CTTGGCATTA  1740
1741  TGGAACGAAG  GGTACATCAT  GGGTTTCATC  AGCAAGGAGC  GCGAGAGAGC  CATTTTGAGC  1800
1801  ACCAAGCCCC  CTGGCACCTT  CCTTCTGCGC  TTCAGCGAGA  GCAGCAAGGA  GGGAGGCATC  1860
1861  ACCTTCACCT  GGGTGGAGAA  AGACATCAGC  GGGAAGACGC  AGATCCAGTC  CGTGGAGCCC  1920
1921  TACACCAAGC  AGCAGCTGAA  CAGCATGTCC  TTCGCCGAGA  TCATCATGGG  CTACAAGATC  1980
1981  ATGGACGCCA  CCAACATCCT  GGTCTCTCCA  CTCGTGTACC  TGTTTCCAGA  GATCCCAAAG  2040
2041  GAGGAAGCGT  TTGGGAAGTA  CTGCCGCACA  GAGAACACCG  AACAACCGGA  TTTCACAGAC  2100
2101  CCAGGTAGCA  CAGTCCCTTA  TCTGAAGACA  AAGTTCATCT  GCGTGACCCC  GTCCCCATCT  2160
2161  GTGTTCATGG  ACATGCCGGA  CAGCGAGCTG  CTGGCCAACG  GATATTCGGG  CACCAATTCG  2220
2221  GGCAACACGA  GCGATCTGTT  CCCCATGTCC  CCTCGCACCC  TGGACTCGCT  GATGCACAAC  2280
2281  GAAGTGCAGG  AACCTAATCC  AGGAGGAGGG  CCTCTGGAAT  CTCTCACCCT  GGATATGGAG  2340
2341  TTCACTTCCG  AGGCAGCCTC  GCCCATGTGA  2370

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Scf-2220Scleropages formosus94.810.01520
LLPS-Asm-2444Astyanax mexicanus94.180.01505
LLPS-Scm-0099Scophthalmus maximus94.030.01468
LLPS-Dar-1615Danio rerio93.920.01504
LLPS-Icp-2361Ictalurus punctatus93.060.01483
LLPS-Orn-0517Oreochromis niloticus92.540.01477
LLPS-Pof-1300Poecilia formosa92.10.01459
LLPS-Orl-0386Oryzias latipes92.050.01472
LLPS-Tar-2090Takifugu rubripes91.770.01471
LLPS-Xim-1442Xiphophorus maculatus91.660.01457
LLPS-Gaa-0547Gasterosteus aculeatus91.280.01469
LLPS-Cas-0450Carlito syrichta89.370.0 722
LLPS-Mam-0418Macaca mulatta86.660.01331
LLPS-Man-0430Macaca nemestrina86.650.0 906
LLPS-Cap-3478Cavia porcellus86.540.01364
LLPS-Mod-0940Monodelphis domestica86.450.01358
LLPS-Caj-3055Callithrix jacchus86.420.01363
LLPS-Aon-2411Aotus nancymaae86.420.01362
LLPS-Sah-0614Sarcophilus harrisii86.420.01367
LLPS-Chs-2888Chlorocebus sabaeus86.420.01363
LLPS-Paa-2240Papio anubis86.420.01363
LLPS-Ova-3472Ovis aries86.420.01365
LLPS-Ran-2567Rattus norvegicus86.420.01363
LLPS-Hos-2566Homo sapiens86.420.01363
LLPS-Urm-1504Ursus maritimus86.420.01357
LLPS-Fec-3339Felis catus86.420.01363
LLPS-Nol-2118Nomascus leucogenys86.420.01363
LLPS-Gaga-1090Gallus gallus86.420.01367
LLPS-Eqc-3915Equus caballus86.420.01357
LLPS-Aim-3816Ailuropoda melanoleuca86.310.01358
LLPS-Mup-1659Mustela putorius furo86.290.01360
LLPS-Bot-3316Bos taurus86.290.01364
LLPS-Orc-1151Oryctolagus cuniculus86.290.01362
LLPS-Otg-4687Otolemur garnettii86.290.01360
LLPS-Mum-2071Mus musculus86.160.01357
LLPS-Fia-0261Ficedula albicollis86.160.01361
LLPS-Meg-1678Meleagris gallopavo86.160.01362
LLPS-Caf-0169Canis familiaris86.160.01360
LLPS-Myl-2630Myotis lucifugus86.090.01354
LLPS-Loa-0314Loxodonta africana86.060.01355
LLPS-Sus-0271Sus scrofa86.040.01353
LLPS-Dio-1489Dipodomys ordii86.040.01355
LLPS-Mea-2711Mesocricetus auratus85.770.01274
LLPS-Anc-2043Anolis carolinensis85.190.01341
LLPS-Ict-0585Ictidomys tridecemlineatus85.150.01179
LLPS-Tag-0564Taeniopygia guttata84.910.01330
LLPS-Gog-0352Gorilla gorilla84.630.01297
LLPS-Pap-2559Pan paniscus84.630.01298
LLPS-Maf-0552Macaca fascicularis84.330.01300
LLPS-Pat-0992Pan troglodytes83.760.01292
LLPS-Fud-2849Fukomys damarensis83.190.01290
LLPS-Poa-0801Pongo abelii83.190.01299
LLPS-Cea-1181Cercocebus atys83.080.01313
LLPS-Xet-1123Xenopus tropicalis81.270.0 666
LLPS-Anp-2332Anas platyrhynchos79.470.01150
LLPS-Rhb-0210Rhinopithecus bieti78.440.01169
LLPS-Lac-0641Latimeria chalumnae77.150.01214
LLPS-Mal-3330Mandrillus leucophaeus77.110.01172
LLPS-Ten-0724Tetraodon nigroviridis51.560.0 711
LLPS-Pes-3622Pelodiscus sinensis49.781e-134 436
LLPS-Ora-3242Ornithorhynchus anatinus34.783e-55 198
LLPS-Tut-2315Tursiops truncatus32.961e-87 300