• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Rhb-0183
DKC1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: DKC1
Ensembl Gene: ENSRBIG00000028457.1
Ensembl Protein: ENSRBIP00000009183.1
Organism: Rhinopithecus bieti
Taxa ID: 61621
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Cajal body, Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSRBIT00000032796.1ENSRBIP00000009183.1
UniProtA0A2K6KD35, A0A2K6KD35_RHIBE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLTRGRALRT  GQASKSHCAD  YQRAPRIPPR  GRPRPLPPHG  KARTGRCAGG  WVLAARPDGT  60
61    EAAGVCGRSL  GCGPGCRHAV  QGNMADAEVI  ILPKKHKKKK  ERKSLPEEDV  AEIQHAEEFL  120
121   IKPESKVAKL  DTSQWPLLLK  NFDKLNVRTT  HYTPLACGSN  PLKREIGDYI  RTGFINLDKP  180
181   SNPSSHEVVA  WIRRILRVEK  TGHSGTLDPK  VTGCLIVCIE  RATRLVKSQQ  SAGKEYVGIV  240
241   RLHNAIEGGT  QLSRALETLT  GALFQRPPLI  AAVKRQLRVR  TIYESKMIEY  DPERRLGIFW  300
301   VSCEAGTYIR  TLCVHLGLLL  GVGGQMQELR  RVRSGVMSEK  DHMVTMHDVL  DAQWLYDNHK  360
361   DESYLRRVVY  PLEKLLTSHK  RLVMKDSAVN  AICYGAKIML  PGVLRYEDGI  EVNQEIVVIT  420
421   TKGEAICMAI  ALMTTAVIST  CDHGIVAKIK  RVIMERDTYP  RKWGLGPKAS  QKKLMIKQGL  480
481   LDKYGKPTES  TPATWKQEYV  DYSETAKKEV  VAEVVKAPQV  VAEAAKTAKR  KRESESESDE  540
541   TPPAAPQLIK  KEKKKSKKDK  KAKAGLESGA  EPGDGDSDTT  KKKKKKKKAK  EVELVSE  597
Nucleotide CDS Sequence (FASTA)
1     ATGCTCACGC  GCGGTCGCGC  CCTCCGTACT  GGCCAAGCCA  GCAAATCGCA  TTGCGCGGAC  60
61    TACCAGCGCG  CGCCTCGGAT  TCCGCCCCGG  GGACGGCCCC  GCCCCCTCCC  GCCCCACGGC  120
121   AAGGCACGCA  CAGGGCGGTG  CGCGGGTGGG  TGGGTCTTAG  CAGCGCGGCC  TGACGGGACC  180
181   GAGGCGGCGG  GAGTCTGCGG  TCGGTCTCTC  GGCTGTGGTC  CGGGCTGCAG  GCACGCGGTG  240
241   CAGGGTAACA  TGGCGGATGC  GGAAGTAATT  ATTTTGCCAA  AGAAACATAA  GAAGAAAAAG  300
301   GAGCGGAAGT  CATTGCCAGA  AGAAGATGTA  GCTGAAATAC  AACACGCTGA  AGAATTTCTT  360
361   ATCAAACCCG  AATCCAAAGT  TGCTAAGTTG  GACACGTCTC  AGTGGCCCCT  TTTGCTAAAG  420
421   AATTTTGATA  AGCTGAATGT  AAGGACAACA  CACTATACAC  CTCTTGCATG  TGGTTCAAAT  480
481   CCTCTAAAGA  GAGAGATTGG  GGACTACATC  AGGACAGGTT  TCATTAATCT  TGACAAGCCC  540
541   TCTAACCCCT  CTTCCCATGA  GGTGGTAGCC  TGGATTCGAC  GGATACTTAG  GGTGGAGAAG  600
601   ACAGGGCACA  GTGGTACTCT  GGATCCCAAG  GTGACTGGTT  GTTTAATCGT  GTGCATAGAA  660
661   CGAGCCACTC  GCTTGGTGAA  GTCACAACAG  AGTGCAGGCA  AAGAGTATGT  GGGGATTGTC  720
721   CGGCTGCACA  ATGCTATTGA  AGGGGGGACC  CAGCTTTCTA  GGGCCCTAGA  AACTCTGACA  780
781   GGTGCCCTAT  TCCAGCGACC  CCCACTTATT  GCTGCAGTAA  AGAGGCAGCT  CCGAGTGAGG  840
841   ACCATCTACG  AGAGCAAAAT  GATTGAATAC  GATCCTGAAA  GAAGATTAGG  GATCTTTTGG  900
901   GTGAGTTGTG  AGGCCGGCAC  CTACATTCGG  ACATTATGTG  TGCACCTTGG  TTTGTTATTG  960
961   GGAGTTGGTG  GTCAGATGCA  GGAGCTTCGG  AGGGTTCGTT  CTGGAGTCAT  GAGTGAAAAG  1020
1021  GACCACATGG  TGACAATGCA  CGATGTGCTT  GATGCTCAGT  GGCTATATGA  TAACCACAAG  1080
1081  GATGAGAGTT  ACCTGCGGCG  AGTTGTTTAC  CCTTTGGAAA  AGTTGTTGAC  ATCTCATAAA  1140
1141  CGGCTGGTTA  TGAAAGACAG  TGCAGTAAAT  GCTATCTGCT  ATGGGGCCAA  GATCATGCTT  1200
1201  CCAGGTGTTC  TTCGATATGA  GGATGGCATT  GAGGTCAATC  AGGAGATTGT  GGTTATCACC  1260
1261  ACCAAAGGAG  AAGCAATCTG  CATGGCTATT  GCGTTAATGA  CCACAGCGGT  CATCTCTACC  1320
1321  TGCGATCATG  GTATAGTAGC  AAAGATCAAG  AGAGTGATCA  TGGAGAGAGA  CACTTACCCT  1380
1381  CGGAAGTGGG  GTTTAGGTCC  AAAGGCAAGT  CAGAAGAAGC  TGATGATCAA  GCAGGGCCTT  1440
1441  CTGGACAAGT  ACGGGAAGCC  CACAGAGAGC  ACGCCTGCCA  CCTGGAAGCA  GGAGTATGTT  1500
1501  GACTACAGTG  AGACTGCCAA  AAAAGAGGTG  GTTGCTGAAG  TGGTAAAAGC  CCCGCAGGTA  1560
1561  GTTGCCGAAG  CAGCAAAAAC  TGCAAAGCGG  AAGCGAGAGA  GTGAGAGTGA  AAGTGACGAG  1620
1621  ACCCCTCCAG  CAGCTCCTCA  GTTGATCAAG  AAGGAAAAGA  AGAAGAGTAA  GAAGGACAAG  1680
1681  AAGGCCAAAG  CTGGTCTGGA  GAGCGGGGCC  GAGCCTGGAG  ATGGGGACAG  TGATACCACC  1740
1741  AAGAAGAAGA  AGAAGAAGAA  GAAAGCAAAA  GAGGTAGAAC  TGGTTTCTGA  GTAG  1794

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-0026Macaca nemestrina100.00.0 874
LLPS-Chs-2531Chlorocebus sabaeus100.00.0 874
LLPS-Mal-0941Mandrillus leucophaeus100.00.0 874
LLPS-Paa-0014Papio anubis100.00.0 874
LLPS-Cea-2583Cercocebus atys99.810.0 875
LLPS-Mam-0266Macaca mulatta99.610.0 866
LLPS-Pat-0345Pan troglodytes99.420.0 871
LLPS-Hos-0558Homo sapiens99.420.0 871
LLPS-Gog-0793Gorilla gorilla99.420.0 871
LLPS-Poa-0508Pongo abelii99.210.0 860
LLPS-Pap-0346Pan paniscus99.030.0 862
LLPS-Nol-0111Nomascus leucogenys99.030.0 869
LLPS-Maf-0565Macaca fascicularis98.490.0 997
LLPS-Caj-0203Callithrix jacchus98.250.0 862
LLPS-Caf-0122Canis familiaris98.10.0 813
LLPS-Aim-1951Ailuropoda melanoleuca97.860.0 810
LLPS-Mup-1615Mustela putorius furo97.620.0 806
LLPS-Urm-1426Ursus maritimus97.350.0 790
LLPS-Aon-1717Aotus nancymaae97.080.0 847
LLPS-Ova-0725Ovis aries96.90.0 801
LLPS-Ora-2161Ornithorhynchus anatinus95.580.0 748
LLPS-Ict-2516Ictidomys tridecemlineatus95.070.0 813
LLPS-Cap-1932Cavia porcellus93.960.0 833
LLPS-Ere-0063Erinaceus europaeus93.610.0 743
LLPS-Orc-2856Oryctolagus cuniculus93.360.0 827
LLPS-Pes-1193Pelodiscus sinensis92.740.0 677
LLPS-Fud-1410Fukomys damarensis92.680.0 809
LLPS-Cas-2384Carlito syrichta92.320.0 834
LLPS-Myl-0886Myotis lucifugus92.140.0 751
LLPS-Eqc-1606Equus caballus91.180.0 815
LLPS-Loa-0322Loxodonta africana91.150.0 798
LLPS-Otg-0578Otolemur garnettii90.840.0 820
LLPS-Fec-1441Felis catus90.660.0 807
LLPS-Mum-0055Mus musculus90.340.0 813
LLPS-Anp-0500Anas platyrhynchos90.330.0 676
LLPS-Tag-0670Taeniopygia guttata90.330.0 677
LLPS-Sah-0749Sarcophilus harrisii89.790.0 748
LLPS-Meg-0620Meleagris gallopavo89.780.0 672
LLPS-Gaga-0058Gallus gallus89.720.0 740
LLPS-Mod-0207Monodelphis domestica89.290.0 741
LLPS-Xet-0419Xenopus tropicalis88.470.0 731
LLPS-Sus-1415Sus scrofa88.420.0 802
LLPS-Lac-0642Latimeria chalumnae88.220.0 731
LLPS-Bot-0093Bos taurus88.130.0 811
LLPS-Leo-1115Lepisosteus oculatus87.660.0 718
LLPS-Orn-0045Oreochromis niloticus87.410.0 712
LLPS-Fia-0268Ficedula albicollis87.410.0 727
LLPS-Tar-0615Takifugu rubripes87.270.0 691
LLPS-Scm-0638Scophthalmus maximus86.720.0 715
LLPS-Asm-0329Astyanax mexicanus86.470.0 707
LLPS-Gaa-0034Gasterosteus aculeatus86.430.0 706
LLPS-Orl-1463Oryzias latipes86.190.0 694
LLPS-Dar-0247Danio rerio85.960.0 708
LLPS-Icp-0595Ictalurus punctatus85.960.0 705
LLPS-Pof-1256Poecilia formosa85.890.0 705
LLPS-Xim-1197Xiphophorus maculatus85.640.0 703
LLPS-Scf-2354Scleropages formosus85.240.0 717
LLPS-Mea-1353Mesocricetus auratus83.671e-165 480
LLPS-Anc-0034Anolis carolinensis83.010.0 742
LLPS-Dio-0958Dipodomys ordii83.07e-165 478
LLPS-Ran-2002Rattus norvegicus81.690.0 735
LLPS-Cii-0652Ciona intestinalis79.590.0 634
LLPS-Cis-0307Ciona savignyi79.540.0 638
LLPS-Php-1206Physcomitrella patens75.390.0 600
LLPS-Drm-0094Drosophila melanogaster74.190.0 628
LLPS-Miv-0371Microbotryum violaceum74.110.0 607
LLPS-Amt-0393Amborella trichopoda74.030.0 599
LLPS-Orp-0500Oryza punctata73.470.0 585
LLPS-Brd-1135Brachypodium distachyon73.470.0 588
LLPS-Prp-0136Prunus persica73.440.0 596
LLPS-Pug-0451Puccinia graminis73.350.0 599
LLPS-Hea-1638Helianthus annuus73.180.0 593
LLPS-Bro-0648Brassica oleracea73.110.0 586
LLPS-Mel-0421Melampsora laricipopulina73.060.0 588
LLPS-Tru-0165Triticum urartu72.970.0 581
LLPS-Tra-0014Triticum aestivum72.970.0 584
LLPS-Coc-0311Corchorus capsularis72.920.0 595
LLPS-Scp-0612Schizosaccharomyces pombe72.870.0 583
LLPS-Brr-1157Brassica rapa72.850.0 581
LLPS-Brn-0842Brassica napus72.850.0 580
LLPS-Lep-1168Leersia perrieri72.850.0 583
LLPS-Met-0956Medicago truncatula72.820.0 591
LLPS-Orb-1065Oryza barthii72.780.0 564
LLPS-Sob-0314Sorghum bicolor72.770.0 585
LLPS-Sei-1618Setaria italica72.770.0 585
LLPS-Sol-1802Solanum lycopersicum72.750.0 581
LLPS-Ors-0220Oryza sativa72.680.0 582
LLPS-Org-0726Oryza glaberrima72.680.0 582
LLPS-Orm-1978Oryza meridionalis72.680.0 582
LLPS-Ori-0696Oryza indica72.680.0 582
LLPS-Thc-1355Theobroma cacao72.660.0 593
LLPS-Mua-0160Musa acuminata72.660.0 588
LLPS-Abg-0562Absidia glauca72.610.0 586
LLPS-Gor-1799Gossypium raimondii72.560.0 590
LLPS-Spr-0018Sporisorium reilianum72.410.0 593
LLPS-Orr-2185Oryza rufipogon72.410.0 579
LLPS-Orgl-0080Oryza glumaepatula72.410.0 579
LLPS-Pot-0331Populus trichocarpa72.40.0 594
LLPS-Usm-0108Ustilago maydis72.340.0 592
LLPS-Nia-0609Nicotiana attenuata72.320.0 585
LLPS-Coo-0163Colletotrichum orbiculare72.272e-177 531
LLPS-Mae-0522Manihot esculenta72.210.0 591
LLPS-Phv-0291Phaseolus vulgaris72.140.0 592
LLPS-Sac-0633Saccharomyces cerevisiae72.140.0 577
LLPS-Viv-1255Vitis vinifera72.090.0 593
LLPS-Fuo-0245Fusarium oxysporum72.060.0 567
LLPS-Fuv-0644Fusarium verticillioides72.060.0 567
LLPS-Cus-0048Cucumis sativus72.060.0 584
LLPS-Osl-0515Ostreococcus lucimarinus72.025e-180 523
LLPS-Orbr-0167Oryza brachyantha71.950.0 581
LLPS-Glm-0281Glycine max71.880.0 588
LLPS-Via-1565Vigna angularis71.880.0 587
LLPS-Asn-0161Aspergillus nidulans71.830.0 575
LLPS-Crn-0520Cryptococcus neoformans71.820.0 596
LLPS-Sot-0265Solanum tuberosum71.80.0 582
LLPS-Tum-0713Tuber melanosporum71.790.0 592
LLPS-Asni-0240Aspergillus niger71.650.0 590
LLPS-Art-0211Arabidopsis thaliana71.540.0 577
LLPS-Arl-0271Arabidopsis lyrata71.540.0 574
LLPS-Zem-0429Zea mays71.50.0 593
LLPS-Yal-0035Yarrowia lipolytica71.50.0 585
LLPS-Cym-0319Cyanidioschyzon merolae71.430.0 560
LLPS-Zyt-0773Zymoseptoria tritici71.430.0 572
LLPS-Vir-0297Vigna radiata71.430.0 564
LLPS-Chr-0327Chlamydomonas reinhardtii71.430.0 575
LLPS-Dos-0077Dothistroma septosporum71.390.0 578
LLPS-Mao-0785Magnaporthe oryzae71.390.0 577
LLPS-Trv-0091Trichoderma virens71.360.0 586
LLPS-Asfu-0108Aspergillus fumigatus71.320.0 582
LLPS-Map-0314Magnaporthe poae71.130.0 577
LLPS-Nef-0078Neosartorya fischeri71.060.0 581
LLPS-Cogr-0221Colletotrichum graminicola71.060.0 556
LLPS-Gag-0173Gaeumannomyces graminis71.060.0 572
LLPS-Fus-0270Fusarium solani70.880.0 567
LLPS-Gas-0229Galdieria sulphuraria70.710.0 580
LLPS-Orni-0123Oryza nivara70.660.0 578
LLPS-Asf-0206Aspergillus flavus70.630.0 581
LLPS-Aso-0117Aspergillus oryzae70.630.0 581
LLPS-Beb-0278Beauveria bassiana70.60.0 575
LLPS-Dac-0194Daucus carota70.450.0 595
LLPS-Trr-0066Trichoderma reesei70.30.0 577
LLPS-Asg-0197Ashbya gossypii70.280.0 570
LLPS-Sem-0468Selaginella moellendorffii70.260.0 574
LLPS-Chc-0316Chondrus crispus70.180.0 576
LLPS-Scj-0391Schizosaccharomyces japonicus70.130.0 572
LLPS-Ten-2285Tetraodon nigroviridis70.00.0 548
LLPS-Scc-0536Schizosaccharomyces cryophilus69.870.0 577
LLPS-Blg-1352Blumeria graminis69.670.0 582
LLPS-Asc-0048Aspergillus clavatus69.620.0 578
LLPS-Lem-0152Leptosphaeria maculans69.590.0 571
LLPS-Cog-0619Colletotrichum gloeosporioides69.40.0 569
LLPS-Ved-0097Verticillium dahliae69.330.0 556
LLPS-Pytr-0237Pyrenophora triticirepentis69.070.0 564
LLPS-Pyt-0896Pyrenophora teres69.070.0 564
LLPS-Kop-0011Komagataella pastoris68.830.0 565
LLPS-Put-0446Puccinia triticina68.020.0 537
LLPS-Cae-0447Caenorhabditis elegans67.670.0 567
LLPS-Nec-0508Neurospora crassa67.440.0 545
LLPS-Phn-0257Phaeosphaeria nodorum67.080.0 561
LLPS-Ast-0053Aspergillus terreus62.271e-170 500
LLPS-Hov-0130Hordeum vulgare32.663e-1789.4
LLPS-Tut-2265Tursiops truncatus25.659e-0960.8