LLPS-Ran-a677
Arfgap2
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). May regulate coatomer-mediated protein transport from the Golgi complex to the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRNOT00000057161.2 | ENSRNOP00000053988.2 |
| UniProt | Q3MID3, ARFG2_RAT | |
| GeneBank | BC101917 | AAI01918.1 |
| RefSeq | NM_001033707.1 | NP_001028879.1 |
| Entrez | 362162 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAGPSKSEI QTLFKRLRAI PTNKACFDCG AKSPSWASIT YGVFLCIDCS GVHRSLGVHL 60 61 SFIRSTELDS NWSWLQLRCM QVGGNANATA FFRQHGCLAN DANTKYNSRA AQMYREKIRQ 120 121 LGSTALARHG TDLWIDNMNS APSHSPEKKD SDFFTEHTQA PAWDTAATDP SGTQQPALPS 180 181 ESSSLAQPEP GPNTDLLGTS PQASLELKSS IIGKKKPAAA KKGLGAKKGL GAQKVSNQSF 240 241 TEIERQAQVA EKLREQQAAD AKKQAEESMV ASMRLAYQEL QIDRKKEEKK LQNLEGKKRE 300 301 QAERLGMGLV SRSSISHSVL SEMQMIEQET PLSAKSSRSQ LDLFDDVGTF ASGPPKYKDN 360 361 PFSLGETFGS RWDSDAAWGM DRVEEKEPEV TISSIRPISE RTTSRREVES RISGLESSEA 420 421 RQKFAGAKAI SSDMFFGREV DSEYEARSRL QQLSGSSAIS SSDLFGDVDG AHGGGTVSLG 480 481 NVLPTADIAQ FKQGVKSVAG KMAVLANGVM NSLQDRYGSY 520 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCGG GCCCGAGCAA GAGCGAAATC CAGACTCTTT TTAAGAGGCT TCGCGCAATT 60 61 CCCACCAACA AGGCCTGTTT CGATTGTGGA GCCAAGAGTC CTAGTTGGGC CAGCATCACG 120 121 TATGGTGTAT TTTTGTGTAT TGACTGCTCT GGAGTGCATC GCTCCTTGGG TGTTCATCTC 180 181 AGCTTTATCA GGTCCACAGA GTTGGATTCG AACTGGAGCT GGTTGCAGCT GAGGTGTATG 240 241 CAGGTCGGCG GGAATGCCAA TGCGACTGCT TTTTTCCGCC AACATGGATG TCTGGCCAAT 300 301 GATGCTAACA CCAAATATAA CAGCCGAGCT GCCCAGATGT ACCGAGAGAA GATCAGGCAG 360 361 TTAGGGAGTA CAGCTCTGGC TAGGCACGGC ACTGATCTTT GGATAGACAA TATGAACAGT 420 421 GCTCCTAGTC ACTCTCCAGA GAAGAAAGAC TCTGATTTCT TCACAGAGCA TACTCAGGCC 480 481 CCTGCTTGGG ATACAGCAGC CACGGATCCT TCAGGGACCC AGCAACCAGC CCTACCTTCA 540 541 GAGAGCAGTA GCCTGGCGCA ACCTGAACCT GGCCCCAACA CTGATCTGCT TGGAACCTCA 600 601 CCCCAAGCCT CTCTGGAACT GAAAAGCTCC ATTATTGGCA AGAAGAAGCC AGCAGCAGCT 660 661 AAGAAAGGGC TGGGTGCCAA GAAAGGCCTG GGAGCTCAGA AGGTGAGCAA CCAGAGCTTT 720 721 ACTGAGATTG AGCGGCAGGC CCAGGTGGCA GAGAAGCTCC GAGAGCAGCA GGCAGCTGAT 780 781 GCCAAGAAGC AGGCAGAAGA GTCCATGGTT GCCTCCATGC GTCTGGCCTA CCAGGAGCTC 840 841 CAGATTGATC GCAAGAAGGA GGAGAAAAAG CTACAGAACC TTGAAGGAAA GAAACGAGAG 900 901 CAGGCTGAAA GGCTGGGCAT GGGCTTGGTG TCCCGAAGCT CCATCTCCCA CTCTGTGCTG 960 961 TCTGAGATGC AGATGATTGA GCAGGAAACC CCGCTGAGTG CAAAATCTTC CCGTTCACAA 1020 1021 CTTGACTTGT TTGATGATGT TGGAACATTT GCTTCTGGAC CCCCAAAGTA CAAGGATAAC 1080 1081 CCCTTTTCTT TGGGAGAAAC TTTTGGTTCC CGCTGGGATT CAGATGCAGC CTGGGGTATG 1140 1141 GACAGGGTAG AAGAGAAGGA ACCTGAAGTT ACCATCTCCA GCATCCGGCC TATTTCAGAA 1200 1201 AGAACCACAA GTCGGAGGGA AGTGGAGAGT CGGATCTCAG GTCTTGAGTC CAGTGAAGCA 1260 1261 CGTCAGAAGT TCGCAGGAGC CAAAGCCATC TCGTCTGACA TGTTCTTTGG TCGAGAGGTG 1320 1321 GACTCTGAGT ATGAAGCCAG GTCTCGGTTA CAGCAGCTTT CGGGCAGCAG TGCCATCAGC 1380 1381 TCTTCAGACC TTTTTGGGGA TGTGGATGGA GCTCATGGAG GAGGAACTGT ATCTCTGGGG 1440 1441 AATGTACTTC CTACAGCTGA CATTGCCCAG TTTAAGCAGG GTGTCAAGTC TGTGGCTGGC 1500 1501 AAGATGGCTG TGCTGGCCAA TGGTGTGATG AATTCTTTAC AGGATCGCTA CGGTTCCTAC 1560 1561 TGA 1563 |
▼ KEYWORD
ID | Family |
3D-structure | |
Acetylation | |
Coiled coil | |
Complete proteome | |
Cytoplasm | |
ER-Golgi transport | |
Golgi apparatus | |
GTPase activation | |
Membrane | |
Metal-binding | |
Phosphoprotein | |
Protein transport | |
Reference proteome | |
Transport | |
Zinc | |
Zinc-finger
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Golgi membrane | |
Cellular Component | Plasma membrane | |
Cellular Component | Trans-Golgi network | |
Molecular Function | GTPase activator activity | |
Molecular Function | Metal ion binding | |
Biological Process | COPI coating of Golgi vesicle | |
Biological Process | Endoplasmic reticulum to Golgi vesicle-mediated transport | |
Biological Process | Protein transport | |
Biological Process | Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| PIRSF | ||||
| Structure | ||||
| PDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | TISSUES | |||
| Element | ||||
| miRWalk | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a692 | Homo sapiens | 0.0 | 970 | undefined |
| LLPS-Mum-a686 | Mus musculus | 0.0 | 1039 | undefined |