LLPS-Poa-1576
GAR1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | H/ACA ribonucleoprotein complex subunit |
| Gene Name: | GAR1, CR201_G0000538 |
| Ensembl Gene: | ENSPPYG00000014996.2 |
| Ensembl Protein: | ENSPPYP00000016749.2 |
| Organism: | Pongo abelii |
| Taxa ID: | 9601 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Cajal body, Nucleolus, P-body | Predicted from orthologs | (View) |
▼ FUNCTION
| Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPPYT00000017429.2 | ENSPPYP00000016749.2 |
| UniProt | A0A2J8XQ76, A0A2J8XQ76_PONAB, H2PE40 | |
| GeneBank | ABGA01229619, ABGA01229620, NDHI03003363 | , PNJ84184.1, PNJ84183.1 |
| RefSeq | XM_002815056.2, XM_009240259.1 | XP_002815102.1, XP_009238534.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSFRGGGRGG FNRGGGGGGF NRGGSSNHFR GGGGGGGGGN FRGGGRGGFG RGGGRGGFNK 60 61 GQDQGPPERV VLLGEFLHPC EDDIVCKCTT DENKVPYFNA PVYLENKEQI GKVDEIFGQL 120 121 RDFYFSVKLS ENMKASSFKK LQKFYIDPYK LLPLQRFLPR PPGEKGPPRG GGRGGRGGGR 180 181 GGGGRGSGRG GGFRGGRGGG GGGFRGGRGG GFRGRGH 217 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTTTTC GAGGCGGAGG TCGTGGAGGC TTTAATCGAG GTGGTGGAGG TGGCGGCTTC 60 61 AACCGAGGCG GCAGCAGCAA CCACTTCCGA GGTGGAGGCG GCGGTGGAGG CGGCGGCAAT 120 121 TTCAGAGGCG GCGGCAGGGG AGGATTTGGA CGAGGGGGTG GCCGCGGAGG CTTTAACAAA 180 181 GGCCAAGACC AAGGACCTCC AGAACGTGTA GTCTTATTAG GAGAGTTCCT GCATCCCTGT 240 241 GAAGATGACA TAGTTTGTAA ATGTACCACA GATGAAAATA AGGTGCCTTA TTTCAATGCT 300 301 CCTGTTTACT TAGAAAACAA AGAACAAATT GGAAAAGTGG ATGAAATATT TGGACAACTT 360 361 AGAGATTTTT ATTTTTCAGT TAAATTGTCA GAAAACATGA AGGCTTCATC CTTTAAAAAA 420 421 CTACAGAAGT TTTATATAGA CCCATATAAG CTGCTGCCAC TGCAGAGGTT TTTACCTCGA 480 481 CCTCCAGGTG AGAAAGGACC TCCAAGAGGT GGTGGCAGGG GAGGCCGAGG AGGAGGAAGA 540 541 GGAGGAGGTG GCAGAGGTAG TGGCAGAGGC GGTGGTTTTA GAGGTGGAAG AGGAGGTGGA 600 601 GGTGGGGGCT TCAGAGGAGG AAGAGGTGGT GGTTTCAGAG GGAGAGGACA TTAA 654 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Box H/ACA snoRNP complex | |
Cellular Component | Box H/ACA telomerase RNP complex | |
Cellular Component | Fibrillar center | |
Cellular Component | Nuclear chromosome, telomeric region | |
Molecular Function | Box H/ACA snoRNA binding | |
Molecular Function | Telomerase RNA binding | |
Biological Process | Pseudouridine synthesis | |
Biological Process | RRNA processing | |
Biological Process | Telomere maintenance via telomerase |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Paa-0185 | Papio anubis | 100.0 | 4e-60 | 194 |
| LLPS-Mal-0479 | Mandrillus leucophaeus | 100.0 | 5e-60 | 194 |
| LLPS-Chs-0786 | Chlorocebus sabaeus | 100.0 | 1e-57 | 187 |
| LLPS-Maf-0107 | Macaca fascicularis | 100.0 | 5e-60 | 194 |
| LLPS-Aon-0671 | Aotus nancymaae | 100.0 | 1e-59 | 194 |
| LLPS-Cea-0044 | Cercocebus atys | 100.0 | 5e-60 | 194 |
| LLPS-Caj-0836 | Callithrix jacchus | 100.0 | 7e-60 | 194 |
| LLPS-Fud-1212 | Fukomys damarensis | 100.0 | 4e-19 | 83.6 |
| LLPS-Mam-0794 | Macaca mulatta | 100.0 | 4e-60 | 194 |
| LLPS-Cas-0103 | Carlito syrichta | 100.0 | 5e-60 | 194 |
| LLPS-Nol-2378 | Nomascus leucogenys | 100.0 | 5e-60 | 194 |
| LLPS-Hos-0993 | Homo sapiens | 100.0 | 4e-60 | 194 |
| LLPS-Pat-2019 | Pan troglodytes | 100.0 | 4e-60 | 194 |
| LLPS-Pap-0854 | Pan paniscus | 100.0 | 4e-60 | 194 |
| LLPS-Man-2023 | Macaca nemestrina | 100.0 | 5e-60 | 194 |
| LLPS-Rhb-1349 | Rhinopithecus bieti | 100.0 | 1e-58 | 191 |
| LLPS-Bot-0535 | Bos taurus | 99.08 | 3e-59 | 192 |
| LLPS-Mup-2108 | Mustela putorius furo | 99.08 | 5e-59 | 191 |
| LLPS-Ova-0130 | Ovis aries | 99.08 | 2e-59 | 192 |
| LLPS-Sus-1588 | Sus scrofa | 99.08 | 3e-59 | 192 |
| LLPS-Gog-1744 | Gorilla gorilla | 99.08 | 7e-60 | 194 |
| LLPS-Cap-0038 | Cavia porcellus | 99.08 | 2e-59 | 192 |
| LLPS-Eqc-1327 | Equus caballus | 99.08 | 8e-59 | 191 |
| LLPS-Fec-1611 | Felis catus | 99.08 | 4e-59 | 191 |
| LLPS-Urm-0908 | Ursus maritimus | 99.08 | 3e-59 | 192 |
| LLPS-Otg-1612 | Otolemur garnettii | 99.08 | 1e-59 | 193 |
| LLPS-Orc-0540 | Oryctolagus cuniculus | 99.08 | 8e-60 | 194 |
| LLPS-Aim-1460 | Ailuropoda melanoleuca | 98.17 | 6e-58 | 188 |
| LLPS-Myl-2008 | Myotis lucifugus | 98.17 | 1e-58 | 191 |
| LLPS-Ran-0527 | Rattus norvegicus | 97.25 | 1e-57 | 188 |
| LLPS-Ict-0232 | Ictidomys tridecemlineatus | 97.25 | 2e-58 | 190 |
| LLPS-Dio-1055 | Dipodomys ordii | 96.33 | 4e-57 | 186 |
| LLPS-Mum-0304 | Mus musculus | 96.33 | 2e-57 | 187 |
| LLPS-Mea-0789 | Mesocricetus auratus | 96.33 | 2e-57 | 187 |
| LLPS-Caf-0515 | Canis familiaris | 95.45 | 3e-52 | 175 |
| LLPS-Ora-0612 | Ornithorhynchus anatinus | 95.28 | 2e-54 | 180 |
| LLPS-Xim-2899 | Xiphophorus maculatus | 94.39 | 1e-54 | 181 |
| LLPS-Orl-1606 | Oryzias latipes | 94.39 | 2e-53 | 179 |
| LLPS-Orn-1633 | Oreochromis niloticus | 94.39 | 1e-53 | 178 |
| LLPS-Leo-1293 | Lepisosteus oculatus | 93.46 | 6e-53 | 176 |
| LLPS-Pof-0845 | Poecilia formosa | 93.46 | 9e-54 | 178 |
| LLPS-Sah-2218 | Sarcophilus harrisii | 93.4 | 1e-52 | 176 |
| LLPS-Fia-2344 | Ficedula albicollis | 93.4 | 5e-53 | 176 |
| LLPS-Mod-1590 | Monodelphis domestica | 92.59 | 4e-53 | 177 |
| LLPS-Pes-2295 | Pelodiscus sinensis | 92.45 | 9e-53 | 175 |
| LLPS-Ten-0831 | Tetraodon nigroviridis | 92.13 | 2e-51 | 171 |
| LLPS-Scm-0886 | Scophthalmus maximus | 91.59 | 6e-52 | 173 |
| LLPS-Dar-1829 | Danio rerio | 91.59 | 9e-52 | 173 |
| LLPS-Gaga-1660 | Gallus gallus | 91.51 | 2e-52 | 174 |
| LLPS-Anc-1705 | Anolis carolinensis | 91.51 | 5e-52 | 173 |
| LLPS-Meg-0407 | Meleagris gallopavo | 91.51 | 3e-52 | 174 |
| LLPS-Scf-2343 | Scleropages formosus | 90.83 | 7e-51 | 171 |
| LLPS-Tar-1404 | Takifugu rubripes | 90.65 | 3e-51 | 171 |
| LLPS-Icp-0106 | Ictalurus punctatus | 89.91 | 1e-52 | 175 |
| LLPS-Tag-0537 | Taeniopygia guttata | 89.9 | 1e-46 | 157 |
| LLPS-Xet-0627 | Xenopus tropicalis | 89.62 | 2e-51 | 172 |
| LLPS-Anp-0226 | Anas platyrhynchos | 89.62 | 5e-51 | 170 |
| LLPS-Asm-0336 | Astyanax mexicanus | 88.79 | 3e-50 | 169 |
| LLPS-Lac-1202 | Latimeria chalumnae | 87.74 | 2e-48 | 162 |
| LLPS-Cii-1559 | Ciona intestinalis | 64.71 | 9e-32 | 120 |
| LLPS-Cis-0301 | Ciona savignyi | 64.71 | 4e-32 | 121 |
| LLPS-Cae-0262 | Caenorhabditis elegans | 60.23 | 7e-27 | 108 |
| LLPS-Drm-0267 | Drosophila melanogaster | 59.09 | 2e-28 | 112 |
| LLPS-Brd-0356 | Brachypodium distachyon | 59.09 | 4e-26 | 105 |
| LLPS-Sei-0010 | Setaria italica | 59.09 | 2e-26 | 106 |
| LLPS-Yal-0169 | Yarrowia lipolytica | 58.54 | 5e-25 | 102 |
| LLPS-Orbr-0216 | Oryza brachyantha | 58.43 | 7e-27 | 106 |
| LLPS-Abg-0905 | Absidia glauca | 58.14 | 5e-25 | 103 |
| LLPS-Coc-0780 | Corchorus capsularis | 57.95 | 8e-26 | 104 |
| LLPS-Zem-0589 | Zea mays | 57.95 | 2e-26 | 106 |
| LLPS-Tru-1052 | Triticum urartu | 57.69 | 9e-22 | 92.4 |
| LLPS-Hov-0806 | Hordeum vulgare | 57.47 | 1e-24 | 101 |
| LLPS-Amt-0555 | Amborella trichopoda | 57.47 | 2e-26 | 105 |
| LLPS-Tra-1311 | Triticum aestivum | 57.3 | 6e-26 | 104 |
| LLPS-Chr-0453 | Chlamydomonas reinhardtii | 57.3 | 9e-26 | 105 |
| LLPS-Php-1358 | Physcomitrella patens | 56.82 | 2e-25 | 103 |
| LLPS-Orp-0463 | Oryza punctata | 56.82 | 5e-25 | 102 |
| LLPS-Sob-0578 | Sorghum bicolor | 56.82 | 4e-25 | 102 |
| LLPS-Orgl-0662 | Oryza glumaepatula | 56.76 | 6e-20 | 87.4 |
| LLPS-Orb-0223 | Oryza barthii | 56.76 | 6e-20 | 87.4 |
| LLPS-Sac-0322 | Saccharomyces cerevisiae | 56.63 | 3e-26 | 105 |
| LLPS-Thc-1004 | Theobroma cacao | 56.32 | 7e-25 | 102 |
| LLPS-Via-0125 | Vigna angularis | 55.93 | 1e-13 | 71.6 |
| LLPS-Lep-0475 | Leersia perrieri | 55.68 | 6e-25 | 102 |
| LLPS-Ori-0056 | Oryza indica | 55.68 | 8e-25 | 102 |
| LLPS-Hea-0571 | Helianthus annuus | 55.68 | 3e-25 | 103 |
| LLPS-Mua-0281 | Musa acuminata | 55.68 | 3e-25 | 103 |
| LLPS-Orni-0279 | Oryza nivara | 55.68 | 8e-25 | 102 |
| LLPS-Orm-0779 | Oryza meridionalis | 55.68 | 8e-25 | 102 |
| LLPS-Orr-0504 | Oryza rufipogon | 55.68 | 8e-25 | 102 |
| LLPS-Ors-0481 | Oryza sativa | 55.68 | 8e-25 | 102 |
| LLPS-Nia-0209 | Nicotiana attenuata | 55.68 | 9e-26 | 104 |
| LLPS-Tum-0252 | Tuber melanosporum | 55.56 | 4e-23 | 97.8 |
| LLPS-Put-0331 | Puccinia triticina | 55.56 | 8e-13 | 68.6 |
| LLPS-Org-0562 | Oryza glaberrima | 55.56 | 2e-21 | 92.4 |
| LLPS-Vir-0382 | Vigna radiata | 55.41 | 1e-19 | 87.0 |
| LLPS-Asg-1120 | Ashbya gossypii | 55.29 | 2e-23 | 98.6 |
| LLPS-Kop-0226 | Komagataella pastoris | 55.17 | 5e-25 | 102 |
| LLPS-Cus-0135 | Cucumis sativus | 55.17 | 1e-24 | 101 |
| LLPS-Gor-1452 | Gossypium raimondii | 55.17 | 2e-23 | 98.6 |
| LLPS-Mae-1587 | Manihot esculenta | 55.17 | 8e-25 | 102 |
| LLPS-Prp-1094 | Prunus persica | 55.06 | 1e-24 | 101 |
| LLPS-Scc-0027 | Schizosaccharomyces cryophilus | 54.88 | 8e-23 | 96.3 |
| LLPS-Sot-0693 | Solanum tuberosum | 54.55 | 5e-25 | 102 |
| LLPS-Pot-0096 | Populus trichocarpa | 54.55 | 2e-25 | 103 |
| LLPS-Met-0079 | Medicago truncatula | 54.02 | 7e-24 | 99.8 |
| LLPS-Viv-0783 | Vitis vinifera | 54.02 | 2e-24 | 100 |
| LLPS-Phv-1081 | Phaseolus vulgaris | 54.02 | 7e-24 | 99.8 |
| LLPS-Glm-1219 | Glycine max | 53.93 | 6e-25 | 102 |
| LLPS-Brn-2184 | Brassica napus | 53.93 | 1e-25 | 104 |
| LLPS-Bro-0704 | Brassica oleracea | 53.93 | 9e-26 | 104 |
| LLPS-Brr-0406 | Brassica rapa | 53.93 | 1e-25 | 104 |
| LLPS-Sol-0028 | Solanum lycopersicum | 53.85 | 5e-21 | 90.5 |
| LLPS-Scj-0051 | Schizosaccharomyces japonicus | 53.66 | 3e-21 | 92.4 |
| LLPS-Scp-1063 | Schizosaccharomyces pombe | 53.57 | 7e-23 | 96.7 |
| LLPS-Arl-0724 | Arabidopsis lyrata | 53.41 | 7e-24 | 99.8 |
| LLPS-Art-0214 | Arabidopsis thaliana | 53.41 | 2e-24 | 101 |
| LLPS-Scs-0492 | Sclerotinia sclerotiorum | 52.94 | 9e-23 | 97.1 |
| LLPS-Spr-0358 | Sporisorium reilianum | 52.94 | 1e-22 | 96.7 |
| LLPS-Crn-0635 | Cryptococcus neoformans | 52.33 | 5e-23 | 97.4 |
| LLPS-Zyt-0995 | Zymoseptoria tritici | 51.76 | 2e-20 | 90.5 |
| LLPS-Usm-0909 | Ustilago maydis | 51.76 | 7e-22 | 94.7 |
| LLPS-Dos-1145 | Dothistroma septosporum | 51.76 | 1e-20 | 91.3 |
| LLPS-Phn-0460 | Phaeosphaeria nodorum | 51.35 | 9e-17 | 79.3 |
| LLPS-Ast-0417 | Aspergillus terreus | 51.35 | 1e-17 | 82.0 |
| LLPS-Lem-0587 | Leptosphaeria maculans | 51.22 | 9e-20 | 88.6 |
| LLPS-Blg-0351 | Blumeria graminis | 51.19 | 1e-22 | 96.3 |
| LLPS-Pytr-0167 | Pyrenophora triticirepentis | 51.16 | 1e-21 | 93.6 |
| LLPS-Gag-0485 | Gaeumannomyces graminis | 50.59 | 2e-20 | 90.5 |
| LLPS-Pyt-0153 | Pyrenophora teres | 50.0 | 2e-21 | 92.8 |
| LLPS-Aso-1120 | Aspergillus oryzae | 50.0 | 6e-17 | 80.9 |
| LLPS-Gas-0182 | Galdieria sulphuraria | 50.0 | 1e-20 | 90.5 |
| LLPS-Asc-0332 | Aspergillus clavatus | 50.0 | 5e-20 | 89.0 |
| LLPS-Nef-0359 | Neosartorya fischeri | 50.0 | 3e-20 | 89.7 |
| LLPS-Ved-0894 | Verticillium dahliae | 49.41 | 1e-20 | 90.9 |
| LLPS-Asf-0887 | Aspergillus flavus | 49.4 | 9e-20 | 89.0 |
| LLPS-Pug-0483 | Puccinia graminis | 49.4 | 1e-20 | 91.3 |
| LLPS-Sem-0263 | Selaginella moellendorffii | 48.84 | 1e-20 | 90.9 |
| LLPS-Map-0769 | Magnaporthe poae | 48.84 | 3e-21 | 92.8 |
| LLPS-Mel-0381 | Melampsora laricipopulina | 48.81 | 2e-20 | 90.9 |
| LLPS-Asn-0019 | Aspergillus nidulans | 48.24 | 3e-20 | 89.4 |
| LLPS-Asni-0197 | Aspergillus niger | 48.24 | 6e-20 | 89.0 |
| LLPS-Beb-0952 | Beauveria bassiana | 47.73 | 2e-19 | 87.4 |
| LLPS-Mao-0800 | Magnaporthe oryzae | 47.62 | 8e-20 | 88.6 |
| LLPS-Trv-0046 | Trichoderma virens | 47.19 | 3e-21 | 92.4 |
| LLPS-Trr-0940 | Trichoderma reesei | 47.19 | 3e-21 | 92.4 |
| LLPS-Miv-0421 | Microbotryum violaceum | 46.43 | 9e-18 | 83.2 |
| LLPS-Coo-0114 | Colletotrichum orbiculare | 46.07 | 2e-20 | 90.1 |
| LLPS-Cogr-0518 | Colletotrichum graminicola | 46.07 | 1e-20 | 91.3 |
| LLPS-Cog-0053 | Colletotrichum gloeosporioides | 46.07 | 1e-20 | 90.9 |
| LLPS-Nec-0159 | Neurospora crassa | 44.71 | 4e-15 | 75.1 |
| LLPS-Cym-0134 | Cyanidioschyzon merolae | 44.44 | 8e-15 | 73.9 |
| LLPS-Fuv-0152 | Fusarium verticillioides | 43.82 | 7e-20 | 89.0 |
| LLPS-Fuo-0698 | Fusarium oxysporum | 43.82 | 7e-20 | 89.0 |
| LLPS-Fus-0642 | Fusarium solani | 43.82 | 6e-20 | 89.0 |
| LLPS-Asfu-0085 | Aspergillus fumigatus | 36.9 | 6e-09 | 57.4 |