LLPS-Php-0266
PHYPA_020058
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Eukaryotic translation initiation factor 3 subunit G |
| Gene Name: | PHYPA_020058, PHYPADRAFT_196691 |
| Ensembl Gene: | Pp3c15_21950 |
| Ensembl Protein: | Pp3c15_21950V3.2 |
| Organism: | Physcomitrella patens |
| Taxa ID: | 3218 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Pp3c15_21950V3.2 | Pp3c15_21950V3.2 |
| Ensembl | Pp3c15_21950V3.1 | Pp3c15_21950V3.1 |
| UniProt | A9TNB3, A9TNB3_PHYPA | |
| GeneBank | DS545160, ABEU02000015 | EDQ55113.1, PNR39778.1 |
| RefSeq | XM_001780052.1 | XP_001780104.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGGRRNLRWG DAAEEDDEIE GVLPPTQVFG PDEKGVKIII EWKKNDDNVR TKVIKTIRVK 60 61 KQMKKLNPAT IRRRSLGKFG DALGQNASDN LTVVSTEEIF LERTRPAGAK AEPEKGADLA 120 121 SLGNASLIVC RTCGKKGDHW TSKCPFKELA ASRGIIAGGE KPPTDDNVPG ISAGAGGKGS 180 181 YVPPSMRYGK GNEGESMKRP GRDDNSIRVT NLSEDTREQD LQELFSPFGS ISRIYVAFDR 240 241 ETGLSRGFAF INFVNRDDAI RAINKLDGYG YDNLILRVEW ATPRADRS 288 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGGAGGCA GAAGGAATTT ACGGTGGGGA GATGCGGCGG AGGAGGATGA CGAAATCGAG 60 61 GGTGTGTTGC CGCCTACGCA AGTTTTTGGT CCTGATGAGA AGGGCGTTAA GATTATCATC 120 121 GAATGGAAGA AAAATGACGA CAATGTGCGT ACCAAGGTCA TCAAGACCAT CCGTGTGAAG 180 181 AAACAGATGA AGAAGCTGAA TCCTGCCACG ATCCGGAGGC GTTCTTTGGG GAAGTTTGGT 240 241 GATGCGCTTG GTCAAAATGC ATCTGATAAC TTAACGGTGG TTTCTACTGA GGAAATCTTT 300 301 CTGGAGAGGA CGAGACCAGC AGGTGCCAAA GCTGAACCTG AGAAAGGAGC CGACCTTGCA 360 361 TCCCTTGGAA ATGCCTCTCT TATTGTATGC AGGACATGCG GAAAGAAGGG AGATCACTGG 420 421 ACCTCTAAGT GTCCTTTCAA GGAGTTGGCT GCATCGAGGG GCATTATTGC TGGAGGCGAG 480 481 AAGCCACCGA CCGACGATAA TGTTCCTGGC ATTTCCGCTG GAGCTGGAGG AAAGGGATCG 540 541 TATGTGCCAC CCAGCATGCG TTATGGTAAG GGTAATGAAG GAGAGAGTAT GAAACGACCA 600 601 GGAAGAGACG ATAATTCTAT CCGAGTTACA AATCTTTCAG AGGATACCCG CGAGCAGGAT 660 661 CTTCAGGAGT TGTTCAGTCC GTTTGGTTCA ATCTCTCGAA TTTACGTTGC GTTTGATCGT 720 721 GAAACTGGGC TTAGCCGTGG CTTTGCTTTC ATCAATTTTG TCAACCGGGA TGATGCTATT 780 781 CGAGCAATCA ACAAGTTGGA TGGTTATGGT TACGATAACC TTATTTTGCG CGTCGAGTGG 840 841 GCAACTCCCA GGGCTGATAG ATCTTAG 867 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Eukaryotic 43S preinitiation complex | |
Cellular Component | Eukaryotic 48S preinitiation complex | |
Cellular Component | Eukaryotic translation initiation factor 3 complex | |
Molecular Function | Translation initiation factor activity | |
Biological Process | Formation of cytoplasmic translation initiation complex |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Sem-0918 | Selaginella moellendorffii | 64.36 | 3e-119 | 350 |
| LLPS-Mae-1623 | Manihot esculenta | 57.2 | 7e-91 | 278 |
| LLPS-Brn-2442 | Brassica napus | 57.14 | 2e-96 | 293 |
| LLPS-Brr-2504 | Brassica rapa | 57.14 | 2e-96 | 293 |
| LLPS-Bro-0120 | Brassica oleracea | 57.14 | 2e-96 | 293 |
| LLPS-Arl-1768 | Arabidopsis lyrata | 56.34 | 9e-94 | 286 |
| LLPS-Prp-2042 | Prunus persica | 56.29 | 5e-96 | 291 |
| LLPS-Thc-0020 | Theobroma cacao | 56.14 | 8e-97 | 294 |
| LLPS-Via-1891 | Vigna angularis | 56.14 | 1e-89 | 275 |
| LLPS-Viv-1958 | Vitis vinifera | 55.93 | 7e-96 | 291 |
| LLPS-Sot-1970 | Solanum tuberosum | 55.9 | 1e-95 | 291 |
| LLPS-Brd-0746 | Brachypodium distachyon | 55.79 | 2e-94 | 288 |
| LLPS-Dac-1504 | Daucus carota | 55.76 | 5e-90 | 276 |
| LLPS-Hea-2564 | Helianthus annuus | 55.76 | 3e-92 | 282 |
| LLPS-Gor-0204 | Gossypium raimondii | 55.64 | 2e-95 | 290 |
| LLPS-Osl-1259 | Ostreococcus lucimarinus | 55.6 | 2e-90 | 276 |
| LLPS-Amt-1362 | Amborella trichopoda | 55.59 | 3e-94 | 287 |
| LLPS-Lep-0479 | Leersia perrieri | 55.44 | 3e-92 | 282 |
| LLPS-Orbr-1672 | Oryza brachyantha | 55.4 | 4e-93 | 284 |
| LLPS-Glm-1979 | Glycine max | 55.24 | 3e-87 | 269 |
| LLPS-Phv-1431 | Phaseolus vulgaris | 54.9 | 2e-89 | 275 |
| LLPS-Pot-2261 | Populus trichocarpa | 54.81 | 2e-92 | 283 |
| LLPS-Mua-0901 | Musa acuminata | 54.79 | 3e-92 | 282 |
| LLPS-Sei-1425 | Setaria italica | 54.67 | 8e-95 | 288 |
| LLPS-Orb-0144 | Oryza barthii | 54.39 | 2e-90 | 277 |
| LLPS-Ori-1924 | Oryza indica | 54.39 | 2e-90 | 277 |
| LLPS-Orni-2064 | Oryza nivara | 54.39 | 2e-90 | 277 |
| LLPS-Orgl-1278 | Oryza glumaepatula | 54.39 | 2e-87 | 278 |
| LLPS-Ors-1554 | Oryza sativa | 54.39 | 2e-90 | 277 |
| LLPS-Orr-1041 | Oryza rufipogon | 54.39 | 2e-90 | 277 |
| LLPS-Org-1079 | Oryza glaberrima | 54.39 | 1e-90 | 278 |
| LLPS-Met-0522 | Medicago truncatula | 54.26 | 8e-90 | 276 |
| LLPS-Cus-1156 | Cucumis sativus | 54.23 | 7e-93 | 283 |
| LLPS-Orp-0250 | Oryza punctata | 54.04 | 4e-90 | 276 |
| LLPS-Hov-0107 | Hordeum vulgare | 53.92 | 8e-90 | 277 |
| LLPS-Nia-2153 | Nicotiana attenuata | 53.82 | 3e-95 | 290 |
| LLPS-Zem-1321 | Zea mays | 53.79 | 9e-93 | 283 |
| LLPS-Coc-2291 | Corchorus capsularis | 53.66 | 4e-93 | 284 |
| LLPS-Sob-1178 | Sorghum bicolor | 53.63 | 3e-90 | 277 |
| LLPS-Tra-1185 | Triticum aestivum | 53.58 | 1e-88 | 273 |
| LLPS-Tru-1850 | Triticum urartu | 52.42 | 1e-78 | 246 |
| LLPS-Sol-1588 | Solanum lycopersicum | 52.26 | 4e-94 | 287 |
| LLPS-Art-2693 | Arabidopsis thaliana | 50.32 | 5e-90 | 277 |
| LLPS-Scf-3138 | Scleropages formosus | 45.45 | 9e-11 | 63.5 |
| LLPS-Chr-0896 | Chlamydomonas reinhardtii | 45.3 | 2e-69 | 223 |
| LLPS-Lac-0998 | Latimeria chalumnae | 44.32 | 6e-57 | 191 |
| LLPS-Ora-2785 | Ornithorhynchus anatinus | 44.3 | 2e-11 | 65.1 |
| LLPS-Caj-1445 | Callithrix jacchus | 44.3 | 1e-11 | 65.9 |
| LLPS-Aim-0835 | Ailuropoda melanoleuca | 44.3 | 4e-12 | 68.6 |
| LLPS-Anp-0737 | Anas platyrhynchos | 44.3 | 3e-11 | 64.7 |
| LLPS-Meg-2763 | Meleagris gallopavo | 44.3 | 2e-11 | 65.5 |
| LLPS-Fia-3459 | Ficedula albicollis | 44.3 | 2e-11 | 64.7 |
| LLPS-Pes-0716 | Pelodiscus sinensis | 44.3 | 4e-11 | 64.3 |
| LLPS-Tag-0075 | Taeniopygia guttata | 44.3 | 3e-11 | 64.3 |
| LLPS-Gaga-1691 | Gallus gallus | 44.3 | 4e-11 | 64.7 |
| LLPS-Aso-0316 | Aspergillus oryzae | 44.29 | 4e-12 | 70.5 |
| LLPS-Asf-0781 | Aspergillus flavus | 44.29 | 4e-12 | 70.5 |
| LLPS-Orl-1765 | Oryzias latipes | 44.15 | 1e-55 | 188 |
| LLPS-Scm-3079 | Scophthalmus maximus | 43.77 | 1e-54 | 186 |
| LLPS-Gaa-3150 | Gasterosteus aculeatus | 43.66 | 1e-58 | 196 |
| LLPS-Dar-3972 | Danio rerio | 43.62 | 3e-56 | 189 |
| LLPS-Orn-3307 | Oreochromis niloticus | 43.06 | 2e-57 | 192 |
| LLPS-Leo-1505 | Lepisosteus oculatus | 43.04 | 2e-11 | 65.9 |
| LLPS-Sah-2013 | Sarcophilus harrisii | 43.04 | 5e-11 | 64.7 |
| LLPS-Tut-1981 | Tursiops truncatus | 42.97 | 9e-56 | 189 |
| LLPS-Sus-3389 | Sus scrofa | 42.86 | 6e-12 | 66.6 |
| LLPS-Aon-1934 | Aotus nancymaae | 42.86 | 6e-12 | 67.4 |
| LLPS-Cea-1114 | Cercocebus atys | 42.86 | 7e-12 | 68.6 |
| LLPS-Mum-2821 | Mus musculus | 42.86 | 7e-12 | 66.2 |
| LLPS-Maf-3895 | Macaca fascicularis | 42.86 | 4e-12 | 68.9 |
| LLPS-Mea-1949 | Mesocricetus auratus | 42.86 | 7e-12 | 66.2 |
| LLPS-Chs-0156 | Chlorocebus sabaeus | 42.86 | 5e-12 | 67.0 |
| LLPS-Fud-1981 | Fukomys damarensis | 42.86 | 4e-12 | 67.0 |
| LLPS-Icp-2563 | Ictalurus punctatus | 42.86 | 4e-58 | 194 |
| LLPS-Gog-0562 | Gorilla gorilla | 42.86 | 8e-12 | 68.6 |
| LLPS-Dio-3232 | Dipodomys ordii | 42.86 | 4e-12 | 67.4 |
| LLPS-Bot-2616 | Bos taurus | 42.86 | 9e-12 | 67.0 |
| LLPS-Mal-0226 | Mandrillus leucophaeus | 42.86 | 6e-12 | 68.6 |
| LLPS-Paa-1441 | Papio anubis | 42.86 | 5e-12 | 68.9 |
| LLPS-Ova-2643 | Ovis aries | 42.86 | 1e-11 | 66.6 |
| LLPS-Myl-1896 | Myotis lucifugus | 42.86 | 6e-12 | 67.4 |
| LLPS-Ran-3628 | Rattus norvegicus | 42.86 | 7e-12 | 66.2 |
| LLPS-Man-0875 | Macaca nemestrina | 42.86 | 5e-12 | 68.6 |
| LLPS-Hos-0652 | Homo sapiens | 42.86 | 5e-12 | 68.9 |
| LLPS-Pap-0634 | Pan paniscus | 42.86 | 5e-12 | 68.9 |
| LLPS-Urm-0444 | Ursus maritimus | 42.86 | 2e-12 | 68.9 |
| LLPS-Rhb-0050 | Rhinopithecus bieti | 42.86 | 8e-12 | 68.2 |
| LLPS-Mam-3392 | Macaca mulatta | 42.86 | 4e-12 | 67.8 |
| LLPS-Caf-0657 | Canis familiaris | 42.86 | 2e-12 | 68.2 |
| LLPS-Cap-3229 | Cavia porcellus | 42.86 | 2e-12 | 67.8 |
| LLPS-Eqc-2009 | Equus caballus | 42.86 | 1e-11 | 68.6 |
| LLPS-Nol-3769 | Nomascus leucogenys | 42.86 | 2e-12 | 67.4 |
| LLPS-Anc-3803 | Anolis carolinensis | 42.86 | 7e-12 | 66.6 |
| LLPS-Ict-4065 | Ictidomys tridecemlineatus | 42.86 | 2e-12 | 68.9 |
| LLPS-Mod-0503 | Monodelphis domestica | 42.75 | 1e-56 | 192 |
| LLPS-Xim-2455 | Xiphophorus maculatus | 42.65 | 5e-57 | 191 |
| LLPS-Otg-0759 | Otolemur garnettii | 42.37 | 4e-57 | 192 |
| LLPS-Asm-3703 | Astyanax mexicanus | 42.35 | 1e-54 | 185 |
| LLPS-Loa-1692 | Loxodonta africana | 42.35 | 3e-12 | 67.4 |
| LLPS-Fec-0245 | Felis catus | 42.18 | 1e-56 | 191 |
| LLPS-Pat-0443 | Pan troglodytes | 42.05 | 8e-12 | 67.4 |
| LLPS-Ten-1748 | Tetraodon nigroviridis | 42.05 | 7e-55 | 187 |
| LLPS-Mup-2536 | Mustela putorius furo | 41.98 | 2e-56 | 191 |
| LLPS-Poa-1688 | Pongo abelii | 41.98 | 3e-56 | 190 |
| LLPS-Pof-0828 | Poecilia formosa | 41.94 | 5e-58 | 194 |
| LLPS-Cas-1362 | Carlito syrichta | 41.6 | 5e-54 | 184 |
| LLPS-Xet-0825 | Xenopus tropicalis | 41.58 | 7e-55 | 186 |
| LLPS-Asn-0516 | Aspergillus nidulans | 41.43 | 2e-10 | 65.5 |
| LLPS-Spr-0965 | Sporisorium reilianum | 41.39 | 1e-51 | 177 |
| LLPS-Usm-0297 | Ustilago maydis | 41.39 | 3e-51 | 177 |
| LLPS-Dos-1237 | Dothistroma septosporum | 41.25 | 1e-10 | 65.9 |
| LLPS-Tar-0567 | Takifugu rubripes | 40.86 | 1e-55 | 187 |
| LLPS-Ast-0306 | Aspergillus terreus | 40.79 | 5e-11 | 67.0 |
| LLPS-Scj-0351 | Schizosaccharomyces japonicus | 40.0 | 3e-10 | 64.7 |
| LLPS-Phn-0462 | Phaeosphaeria nodorum | 39.85 | 5e-45 | 159 |
| LLPS-Drm-1012 | Drosophila melanogaster | 39.47 | 2e-10 | 65.1 |
| LLPS-Scp-1443 | Schizosaccharomyces pombe | 39.19 | 6e-50 | 172 |
| LLPS-Mel-0013 | Melampsora laricipopulina | 38.99 | 6e-44 | 157 |
| LLPS-Pyt-1422 | Pyrenophora teres | 38.96 | 2e-07 | 55.8 |
| LLPS-Put-0827 | Puccinia triticina | 38.77 | 1e-48 | 170 |
| LLPS-Pytr-0136 | Pyrenophora triticirepentis | 38.58 | 2e-47 | 166 |
| LLPS-Pug-1355 | Puccinia graminis | 38.57 | 1e-47 | 167 |
| LLPS-Asc-0149 | Aspergillus clavatus | 38.46 | 3e-45 | 160 |
| LLPS-Zyt-0868 | Zymoseptoria tritici | 38.22 | 1e-31 | 124 |
| LLPS-Asfu-0217 | Aspergillus fumigatus | 38.16 | 3e-10 | 64.7 |
| LLPS-Asni-0724 | Aspergillus niger | 38.15 | 7e-46 | 162 |
| LLPS-Lem-1004 | Leptosphaeria maculans | 37.59 | 4e-44 | 157 |
| LLPS-Nef-0813 | Neosartorya fischeri | 37.59 | 9e-47 | 164 |
| LLPS-Cym-0809 | Cyanidioschyzon merolae | 37.58 | 2e-47 | 168 |
| LLPS-Cii-0445 | Ciona intestinalis | 37.46 | 3e-40 | 147 |
| LLPS-Gas-0839 | Galdieria sulphuraria | 37.41 | 5e-45 | 160 |
| LLPS-Trv-0510 | Trichoderma virens | 37.27 | 8e-50 | 172 |
| LLPS-Abg-1202 | Absidia glauca | 37.22 | 7e-47 | 165 |
| LLPS-Tum-0960 | Tuber melanosporum | 37.04 | 8e-42 | 151 |
| LLPS-Scc-0623 | Schizosaccharomyces cryophilus | 37.0 | 3e-44 | 158 |
| LLPS-Chc-0680 | Chondrus crispus | 36.79 | 5e-36 | 137 |
| LLPS-Trr-0947 | Trichoderma reesei | 36.53 | 4e-41 | 150 |
| LLPS-Blg-1178 | Blumeria graminis | 36.24 | 2e-44 | 158 |
| LLPS-Crn-0077 | Cryptococcus neoformans | 36.17 | 4e-36 | 136 |
| LLPS-Fuo-0584 | Fusarium oxysporum | 36.13 | 1e-38 | 143 |
| LLPS-Ved-0715 | Verticillium dahliae | 36.13 | 4e-40 | 147 |
| LLPS-Miv-1020 | Microbotryum violaceum | 35.94 | 1e-46 | 164 |
| LLPS-Beb-0564 | Beauveria bassiana | 35.4 | 7e-39 | 144 |
| LLPS-Fuv-0398 | Fusarium verticillioides | 35.0 | 1e-41 | 151 |
| LLPS-Cogr-0917 | Colletotrichum graminicola | 34.91 | 1e-40 | 149 |
| LLPS-Fus-1284 | Fusarium solani | 34.56 | 6e-39 | 144 |
| LLPS-Nec-1329 | Neurospora crassa | 34.55 | 1e-33 | 131 |
| LLPS-Cog-0260 | Colletotrichum gloeosporioides | 34.18 | 2e-36 | 143 |
| LLPS-Yal-0641 | Yarrowia lipolytica | 34.08 | 3e-31 | 123 |
| LLPS-Coo-0769 | Colletotrichum orbiculare | 33.55 | 6e-41 | 149 |
| LLPS-Sac-0178 | Saccharomyces cerevisiae | 33.46 | 2e-30 | 121 |
| LLPS-Mao-0209 | Magnaporthe oryzae | 33.33 | 3e-34 | 132 |
| LLPS-Kop-0781 | Komagataella pastoris | 32.64 | 8e-30 | 119 |
| LLPS-Asg-0979 | Ashbya gossypii | 31.85 | 5e-31 | 122 |
| LLPS-Cae-1909 | Caenorhabditis elegans | 30.25 | 7e-27 | 110 |