LLPS-Pat-a944
ADCY5
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Adenylate cyclase |
| Gene Name: | ADCY5 |
| Ensembl Gene: | ENSPTRG00000015304.5 |
| Ensembl Protein: | ENSPTRP00000079563.1 |
| Organism: | Pan troglodytes |
| Taxa ID: | 9598 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPTRT00000102028.1 | ENSPTRP00000079563.1 |
| Ensembl | ENSPTRT00000028585.4 | ENSPTRP00000026385.4 |
| Ensembl | ENSPTRT00000080923.1 | ENSPTRP00000080872.1 |
| Ensembl | ENSPTRT00000109712.1 | ENSPTRP00000073964.1 |
| UniProt | H2QN88, H2QN88_PANTR | |
| GeneBank | AACZ04048121 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSGSKSVSPP GYAAQKTAAP APRGGPEHRS AWGEADSRAN GYPHAPGGSA RGSTKKPGGA 60 61 VTPQQQQRLA SRWRSDDDDP PLSGDDPLAG GFGFSFRSKS AWQERGGDDC GRGSRRQRRG 120 121 AASGGSTRAP PVRPRSVEVG LGRAADEVEA GAVEGGEGSG DGGSSADSGS GAGPGAVLSL 180 181 GACCLALLQI FRSKKFPSDK LERLYQRYFF RLNQSSLTML MAVLVLVCLV MLAFHAARPP 240 241 LQLPYLAVLA AAVGVILIMA VLCNRAAFHQ DHMGLACYAL IAVVLAVQVV GLLLPQPRSA 300 301 SEGIWWTVFF IYTIYTLLPV RMRAAVLSGV LLSALHLAIA LRTNAQDQFL LKQLVSNVLI 360 361 FSCTNIVGVC THYPAEVSQR QAFQETRECI QARLHSQREN QQQERLLLSV LPRHVAMEMK 420 421 ADINAKQEDM MFHKIYIQKH DNVSILFADI EGFTSLASQC TAQELVMTLN ELFARFDKLA 480 481 AENHCLRIKI LGDCYYCVSG LPEARADHAH CCVEMGMDMI EAISLVREVT GVNVNMRVGI 540 541 HSGRVHCGVL GLRKWQFDVW SNDVTLANHM EAGGKAGRIH ITKATLNYLN GDYEVEPGCG 600 601 GERNAYLKEH SIETFLILRC TQKRKEEKAM IAKMNRQRTN SIGHNPPHWG AERPFYNHLG 660 661 GNQVSKEMKR MGFEDPKDKN AQESANPEDE VDEFLGRAID ARSIDRLRSE HVRKFLLTFR 720 721 EPDLEKKYSK QVDDRFGAYV ACASLVFLFI CFVQITIVPH SVFMLSFYLT CSLLLTLVVF 780 781 VSVIYSCVKL FPSPLQTLSR KIVRSKMNST LVGVFTITLV FLAAFVNMFT CNSRDLLGCL 840 841 AQEHNISTSQ VNACHVAESA VNYSLGDEQG FCGSPWPNCN FPEYFTYSVL LSLLACSVFL 900 901 QISCIGKLVL MLAIELIYVL IVEVPGVTLF DNADLLVTAN AIDFFNNGTS QCPEHATKVA 960 961 LKVVTPIIIS VFVLALYLHA QQVESTARLD FLWKLQATEE KEEMEELQAY NRRLLHNILP 1020 1021 KDVAAHFLAR ERRNDELYYQ SCECVAVMFA SIANFSEFYV ELEANNEGVE CLRLLNEIIA 1080 1081 DFDEIISEDR FRQLEKIKTI GSTYMAASGL NDSTYDKVGK THIKALADFA MKLMDQMKYI 1140 1141 NEHSFNNFQM KIGLNIGPVV AGVIGARKPQ YDIWGNTVNV ASRMDSTGVP DRIQVTTDMY 1200 1201 QVLAANTYQL ECRGVVKVKG KGEMMTYFLN GGPPLS 1236 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCCGGCT CCAAAAGCGT GAGCCCCCCG GGCTACGCGG CGCAGAAGAC TGCGGCGCCG 60 61 GCGCCCCGGG GAGGCCCCGA ACACCGCTCG GCGTGGGGCG AGGCCGATTC CCGCGCGAAT 120 121 GGCTACCCCC ATGCCCCCGG GGGTTCTGCC CGCGGCTCCA CCAAGAAACC CGGGGGGGCG 180 181 GTGACCCCGC AGCAGCAGCA GCGCCTGGCC AGCCGCTGGC GCAGCGACGA CGACGATCCT 240 241 CCGCTGAGCG GTGATGACCC CCTGGCCGGG GGCTTCGGTT TCAGCTTCCG CTCCAAGTCC 300 301 GCCTGGCAGG AGCGCGGCGG CGACGACTGC GGTCGCGGCA GCCGCCGGCA GCGGCGGGGC 360 361 GCGGCCAGCG GGGGCAGCAC CCGGGCGCCC CCTGCGGGCG GCGGCGGCGG CTCGGCGGCG 420 421 GCGGCTGCCT CGGCGGGCGG GACGGAGGTG CGCCCTCGCT CGGTGGAGGT GGGTCTGGAG 480 481 GAGCGGCGGG GCAAGGGGCG CGCGGCCGAC GAGGTGGAGG CCGGCGCCGT CGAGGGCGGC 540 541 GAGGGGTCCG GGGATGGCGG CAGCTCGGCG GACTCGGGCT CGGGCGCGGG GCCCGGCGCG 600 601 GTGCTGTCCC TGGGCGCCTG CTGCCTGGCG TTGCTGCAGA TATTCCGCTC CAAGAAGTTC 660 661 CCGTCGGACA AACTGGAGCG GCTGTACCAG CGCTACTTCT TCCGCCTGAA CCAGAGCAGC 720 721 CTCACCATGC TCATGGCCGT GCTGGTGCTC GTGTGCCTGG TCATGTTGGC CTTCCACGCG 780 781 GCGCGGCCCC CGCTCCAGCT GCCCTACCTG GCCGTGCTGG CGGCCGCCGT CGGCGTGATC 840 841 CTCATCATGG CTGTGCTTTG CAACCGCGCC GCCTTCCACC AGGACCACAT GGGCCTGGCC 900 901 TGCTATGCGC TCATCGCCGT GGTGCTGGCC GTCCAGGTGG TGGGCCTGCT GCTGCCGCAG 960 961 CCACGCAGCG CCTCTGAGGG CATCTGGTGG ACCGTGTTCT TCATCTACAC CATCTACACG 1020 1021 CTGCTGCCCG TGCGCATGCG AGCCGCAGTG CTCAGCGGGG TGCTCCTGTC CGCCCTCCAC 1080 1081 CTGGCCATCG CCCTGCGCAC CAACGCCCAG GACCAGTTCC TGCTGAAGCA GCTTGTCTCC 1140 1141 AATGTTCTCA TTTTCTCCTG CACCAACATC GTGGGTGTCT GCACCCACTA TCCGGCTGAG 1200 1201 GTCTCCCAGA GACAGGCTTT CCAGGAGACC CGAGAGTGCA TCCAGGCGCG GCTCCACTCG 1260 1261 CAGCGGGAGA ACCAGCAGCA GGAACGGCTC CTGCTGTCTG TCCTTCCCCG TCATGTTGCC 1320 1321 ATGGAGATGA AAGCAGACAT CAACGCCAAG CAGGAGGATA TGATGTTCCA TAAGATTTAC 1380 1381 ATCCAGAAAC ATGACAACGT GAGCATCCTG TTTGCTGACA TCGAGGGCTT CACCAGCCTG 1440 1441 GCGTCCCAGT GCACTGCACA GGAACTGGTC ATGACCCTCA ACGAGCTCTT CGCCCGCTTT 1500 1501 GACAAGCTGG CCGCAGAGAA TCACTGTTTA CGTATTAAGA TCCTCGGGGA TTGTTATTAC 1560 1561 TGCGTCTCGG GGCTGCCTGA AGCGAGGGCT GACCACGCCC ACTGCTGTGT GGAGATGGGC 1620 1621 ATGGACATGA TCGAGGCCAT CTCGTTGGTC CGGGAGGTGA CAGGGGTGAA CGTGAACATG 1680 1681 CGTGTGGGAA TTCACAGCGG GCGAGTACAC TGCGGTGTCC TTGGTCTCAG GAAGTGGCAG 1740 1741 TTCGACGTCT GGTCTAACGA TGTCACGCTA GCCAACCACA TGGAGGCTGG CGGCAAGGCG 1800 1801 GGACGCATCC ACATCACCAA GGCTACACTC AACTACCTGA ATGGGGACTA CGAGGTGGAG 1860 1861 CCAGGCTGTG GGGGCGAGCG CAACGCCTAC CTCAAGGAGC ACAGTATCGA GACCTTCCTC 1920 1921 ATCCTGCGCT GCACCCAGAA GCGGAAAGAA GAGAAGGCCA TGATCGCCAA GATGAACCGC 1980 1981 CAGAGAACCA ACTCCATCGG GCACAACCCA CCACACTGGG GGGCTGAGCG CCCCTTCTAC 2040 2041 AACCACCTGG GTGGCAACCA GGTGTCCAAG GAGATGAAGC GGATGGGCTT TGAAGACCCC 2100 2101 AAGGACAAGA ACGCCCAGGA GAGTGCGAAC CCTGAGGATG AAGTGGATGA GTTTCTGGGC 2160 2161 CGTGCCATTG ACGCCAGGAG CATCGATAGG CTTCGGTCTG AGCACGTCCG CAAGTTCCTC 2220 2221 CTGACCTTCA GGGAGCCTGA CTTAGAGAAG AAGTACTCCA AGCAGGTAGA CGACCGATTT 2280 2281 GGTGCCTATG TGGCGTGTGC CTCGCTCGTC TTCCTCTTCA TCTGCTTTGT CCAGATCACC 2340 2341 ATCGTGCCCC ACTCCGTATT CATGCTCAGC TTCTACCTGA CCTGTTCCCT GCTGCTGACC 2400 2401 TTGGTGGTGT TTGTGTCTGT GATCTACTCC TGCGTAAAGG TG 2442 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cilium | |
Cellular Component | Integral component of plasma membrane | |
Cellular Component | Intermediate filament cytoskeleton | |
Molecular Function | Adenylate cyclase activity | |
Molecular Function | Adenylate cyclase binding | |
Molecular Function | ATP binding | |
Molecular Function | Metal ion binding | |
Molecular Function | Protein heterodimerization activity | |
Molecular Function | Scaffold protein binding | |
Biological Process | Adenosine receptor signaling pathway | |
Biological Process | Adenylate cyclase-activating dopamine receptor signaling pathway | |
Biological Process | Adenylate cyclase-activating G protein-coupled receptor signaling pathway | |
Biological Process | Adenylate cyclase-inhibiting dopamine receptor signaling pathway | |
Biological Process | CAMP biosynthetic process | |
Biological Process | Cellular response to forskolin | |
Biological Process | Locomotory behavior | |
Biological Process | Neuromuscular process controlling balance | |
Biological Process | Positive regulation of cytosolic calcium ion concentration | |
Biological Process | Regulation of insulin secretion involved in cellular response to glucose stimulus |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a957 | Homo sapiens | 0.0 | 2549 | undefined |
| LLPS-Mum-a942 | Mus musculus | 0.0 | 2341 | undefined |