• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pat-3558
PXN

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: PXN isoform 9
Gene Name: PXN, CK820_G0021696
Ensembl Gene: ENSPTRG00000005527.7
Ensembl Protein: ENSPTRP00000073475.1
Organism: Pan troglodytes
Taxa ID: 9598
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDDLDALLAD  LESTTSHISK  RPVFLSEETP  YSYPTGNHTY  QEIAVPPPVP  PPPSSEALNG  60
61    TILDPLDQWQ  PSGSRFIHQQ  PQSSSPVYGS  SAKTSSVSNP  QDGVGSPCSR  VGEEEHVYSF  120
121   PNKQKSAEPS  PTVMSTSLGS  NLSELDRLLL  ELNAVQHNPP  GFPADEANSS  PPLPGALSPL  180
181   YGVPETNSPL  GGKAGPLTKE  KPKRNGGRGL  EDVRPSVESL  LDELESSVPS  PVPAITVNQG  240
241   EMSSPQRVTS  TQQQTRISAS  SATRELDELM  ASLSDFKTSS  STVALSAPGL  SSSAPSSYCS  300
301   LSPSPPPMPS  VFLPPTTTPS  PRGQGHTPEF  PCTEQSGRGL  LPPVAPSWLD  LAGLGVMPDT  360
361   LNSRSPSVEG  SLWAVGTESQ  GRDWRHLPTI  TSELSGAPRC  HTVPCAGSTA  LQEPGEPQGP  420
421   PASPSCPEEA  LAATWEQPWA  SEVFRPERMP  PSGAARSFQE  VTEPAVVAVD  RQAIFPDTWT  480
481   LTEEHGLQQE  RPRPEPGRLG  SSSPASVTTE  QLGAKMTDRG  SVARPTQGPE  TPRSPEGTTE  540
541   AATQDGKEQP  ELPCAMAMGT  PSTTERISTS  GQIRSVIRRS  RESGHAHPMS  REPSPRRRLD  600
601   PATLSRTPSQ  EQLIAELQGR  LGIQPEAEEP  AEAAGPSAQD  WLTEGVIITV  QPRGKRAGGQ  660
661   LVEKVVFPPG  SPIPLRRTIS  VLASPSVPLL  QHRTDAAASS  SSPLPSLLAS  SPLGPSAYTC  720
721   GSSGVQSAGE  EPHDEGVQGP  ALPTPAPHTM  RSVGCQTDED  PLFPPMQIQG  LEQRADGERC  780
781   WAAGWPRDGG  RSSPGGQDEG  GFMAQGKTGS  SSPPGGPPKP  GSQLDSMLGS  LQSDLNKLGV  840
841   ATVAKGVCGA  CKKPIAGQVV  TAMGKTWHPE  HFVCTHCQEE  IGSRNFFERD  GQPYCEKDYH  900
901   NLFSPRCYYC  NGPILDKVVT  ALDRTWHPEH  FFCAQCGAFF  GPEGFHEKDG  KAYCRKDYFD  960
961   MFAPKCGGCA  RAILENYISA  LNTLWHPECF  VCRECFTPFV  NGSFFEHDGQ  PYCEVHYHER  1020
1021  RGSLCSGCQK  PITGRCITAM  AKKFHPEHFV  CAFCLKQLNK  GTFKEQNDKP  YCQNCFLKLF  1080
1081  C  1081
Nucleotide CDS Sequence (FASTA)
1     ATGGACGACC  TCGACGCCCT  GCTGGCGGAC  TTGGAGTCTA  CCACCTCCCA  CATCTCCAAA  60
61    CGGCCTGTGT  TCTTGTCGGA  GGAGACCCCC  TACTCATACC  CAACTGGAAA  CCACACATAC  120
121   CAGGAGATTG  CCGTGCCACC  CCCCGTCCCC  CCACCCCCGT  CCAGCGAGGC  CCTCAATGGC  180
181   ACAATCCTTG  ACCCCTTAGA  CCAGTGGCAG  CCCAGCGGCT  CCCGATTCAT  CCACCAGCAG  240
241   CCTCAGTCCT  CATCACCTGT  GTACGGCTCC  AGTGCCAAAA  CTTCCAGTGT  CTCCAACCCT  300
301   CAGGACGGTG  TTGGCTCTCC  GTGCTCCCGA  GTGGGTGAGG  AGGAGCACGT  CTACAGCTTC  360
361   CCCAACAAGC  AGAAATCAGC  TGAGCCTTCA  CCCACCGTAA  TGAGCACGTC  CCTGGGCAGC  420
421   AACCTTTCTG  AACTCGACCG  CCTGCTGCTG  GAACTGAACG  CTGTACAGCA  TAACCCACCA  480
481   GGCTTCCCTG  CAGATGAGGC  CAACTCAAGC  CCCCCGCTTC  CTGGGGCCCT  GAGCCCCCTC  540
541   TATGGTGTCC  CAGAGACTAA  CAGCCCCTTG  GGAGGCAAAG  CTGGGCCCCT  GACGAAAGAG  600
601   AAGCCTAAGC  GGAATGGGGG  CCGGGGCCTG  GAGGACGTGC  GGCCCAGTGT  GGAGAGTCTC  660
661   TTGGATGAAC  TGGAGAGCTC  CGTGCCCAGC  CCCGTCCCTG  CCATCACTGT  GAACCAGGGC  720
721   GAGATGAGCA  GCCCGCAGCG  CGTCACCTCC  ACCCAACAGC  AGACACGCAT  CTCGGCCTCC  780
781   TCTGCCACCA  GGGAGCTGGA  CGAGCTGATG  GCTTCGCTGT  CGGATTTCAA  GTTCATGGCC  840
841   CAGGGGAAGA  CAGGGAGCAG  CTCACCCCCT  GGGGGGCCCC  CGAAGCCCGG  GAGCCAGCTA  900
901   GACAGCATGC  TGGGGAGCCT  GCAGTCTGAC  CTGAACAAGC  TGGGGGTCGC  CACGGTCGCC  960
961   AAAGGAGTCT  GCGGGGCCTG  CAAGAAGCCC  ATCGCCGGGC  AGGTTGTGAC  CGCCATGGGG  1020
1021  AAGACGTGGC  ACCCCGAGCA  CTTCGTCTGC  ACCCACTGCC  AGGAGGAGAT  CGGATCCCGG  1080
1081  AACTTCTTCG  AGCGGGATGG  ACAGCCCTAC  TGTGAAAAGG  ACTACCACAA  CCTCTTCTCC  1140
1141  CCGCGCTGCT  ACTACTGCAA  CGGCCCCATC  CTGGATAAAG  TGGTGACAGC  CCTTGACCGG  1200
1201  ACGTGGCACC  CTGAACACTT  CTTCTGTGCG  CAGTGTGGAG  CCTTCTTTGG  TCCCGAAGGG  1260
1261  TTCCACGAGA  AGGATGGCAA  GGCCTACTGC  CGCAAGGACT  ACTTCGACAT  GTTCGCACCC  1320
1321  AAGTGTGGCG  GCTGCGCCCG  GGCCATCCTG  GAGAACTATA  TCTCAGCCCT  CAACACGCTG  1380
1381  TGGCATCCTG  AGTGCTTTGT  GTGCCGGGAA  TGCTTCACGC  CATTCGTGAA  CGGCAGCTTC  1440
1441  TTCGAGCACG  ACGGGCAGCC  CTACTGTGAG  GTGCACTACC  ACGAGCGGCG  CGGCTCGCTG  1500
1501  TGTTCTGGCT  GCCAGAAGCC  CATCACCGGC  CGCTGCATCA  CCGCCATGGC  CAAGAAGTTC  1560
1561  CACCCCGAGC  ACTTCGTCTG  TGCCTTCTGC  CTCAAGCAGC  TCAACAAGGG  CACCTTCAAG  1620
1621  GAGCAGAACG  ACAAGCCTTA  CTGTCAGAAC  TGCTTCCTCA  AGCTCTTCTG  CTAG  1674

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orc-1653Oryctolagus cuniculus100.00.0 583
LLPS-Pap-1049Pan paniscus100.00.01875
LLPS-Sus-0817Sus scrofa100.00.0 582
LLPS-Ict-0727Ictidomys tridecemlineatus99.640.0 579
LLPS-Dio-1618Dipodomys ordii99.640.0 582
LLPS-Poa-2082Pongo abelii99.256e-126 396
LLPS-Anc-2974Anolis carolinensis99.230.0 583
LLPS-Hos-1725Homo sapiens99.160.01854
LLPS-Gog-0813Gorilla gorilla99.070.01852
LLPS-Mam-2617Macaca mulatta99.050.0 654
LLPS-Chs-3577Chlorocebus sabaeus99.050.0 655
LLPS-Sah-2697Sarcophilus harrisii98.930.0 571
LLPS-Mod-0146Monodelphis domestica98.570.0 575
LLPS-Ran-2142Rattus norvegicus98.570.0 579
LLPS-Meg-1234Meleagris gallopavo98.460.0 578
LLPS-Fia-2959Ficedula albicollis97.50.0 583
LLPS-Nol-3120Nomascus leucogenys96.730.01850
LLPS-Xet-2260Xenopus tropicalis96.530.0 572
LLPS-Caf-0233Canis familiaris96.520.0 629
LLPS-Mup-2403Mustela putorius furo96.520.0 629
LLPS-Aim-1708Ailuropoda melanoleuca96.20.0 628
LLPS-Myl-2865Myotis lucifugus95.890.0 633
LLPS-Fud-2725Fukomys damarensis95.890.0 633
LLPS-Bot-2493Bos taurus95.870.0 629
LLPS-Leo-2972Lepisosteus oculatus95.816e-114 356
LLPS-Otg-3739Otolemur garnettii95.570.0 626
LLPS-Cap-3433Cavia porcellus95.250.0 628
LLPS-Orn-1343Oreochromis niloticus94.960.0 555
LLPS-Cea-4435Cercocebus atys94.860.01805
LLPS-Maf-1886Macaca fascicularis94.860.01805
LLPS-Rhb-4661Rhinopithecus bieti94.770.01808
LLPS-Man-0483Macaca nemestrina94.770.01803
LLPS-Mea-2257Mesocricetus auratus94.620.0 627
LLPS-Mum-4146Mus musculus94.620.0 624
LLPS-Mal-3031Mandrillus leucophaeus94.490.01796
LLPS-Paa-1342Papio anubis94.490.01796
LLPS-Ova-3303Ovis aries94.320.0 612
LLPS-Ten-1242Tetraodon nigroviridis94.190.0 555
LLPS-Pof-4104Poecilia formosa94.190.0 547
LLPS-Scf-4063Scleropages formosus94.190.0 560
LLPS-Asm-0080Astyanax mexicanus94.190.0 549
LLPS-Icp-0948Ictalurus punctatus93.80.0 548
LLPS-Dar-0235Danio rerio93.410.0 555
LLPS-Gaa-3580Gasterosteus aculeatus93.410.0 548
LLPS-Loa-4292Loxodonta africana93.080.0 595
LLPS-Tar-1003Takifugu rubripes92.640.0 553
LLPS-Tag-0713Taeniopygia guttata92.510.0 592
LLPS-Caj-1539Callithrix jacchus91.150.01732
LLPS-Aon-0125Aotus nancymaae90.50.01689
LLPS-Anp-1653Anas platyrhynchos90.220.0 592
LLPS-Ora-2508Ornithorhynchus anatinus87.970.0 571
LLPS-Pes-2365Pelodiscus sinensis84.180.0 550
LLPS-Eqc-1389Equus caballus82.90.01472
LLPS-Fec-0520Felis catus82.90.01492
LLPS-Gaga-3536Gallus gallus82.227e-87 311
LLPS-Lac-3465Latimeria chalumnae80.870.0 609
LLPS-Scm-1826Scophthalmus maximus79.820.0 576
LLPS-Urm-1946Ursus maritimus79.680.01412
LLPS-Orl-3907Oryzias latipes78.120.0 579
LLPS-Tut-0630Tursiops truncatus77.320.0 759
LLPS-Xim-2282Xiphophorus maculatus76.90.0 569
LLPS-Cis-0627Ciona savignyi73.151e-141 441
LLPS-Cii-0690Ciona intestinalis73.159e-141 436
LLPS-Cae-1248Caenorhabditis elegans53.74e-99 326
LLPS-Asni-0817Aspergillus niger43.893e-37 149
LLPS-Ast-0996Aspergillus terreus41.156e-34 144
LLPS-Crn-0147Cryptococcus neoformans39.684e-0655.1
LLPS-Asc-1074Aspergillus clavatus39.582e-33 143
LLPS-Asfu-1221Aspergillus fumigatus38.617e-33 141
LLPS-Nef-0071Neosartorya fischeri38.611e-32 140
LLPS-Spr-0203Sporisorium reilianum37.847e-40 164
LLPS-Tum-1534Tuber melanosporum37.432e-31 136
LLPS-Usm-1142Ustilago maydis36.942e-40 166
LLPS-Pug-0994Puccinia graminis35.058e-33 139