• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-1708
PXN

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Paxillin
Gene Name: PXN
Ensembl Gene: ENSAMEG00000005166.1
Ensembl Protein: ENSAMEP00000005476.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000005701.1ENSAMEP00000005476.1
UniProtG1LEY9, G1LEY9_AILME
GeneBankACTA01147330

▼ SEQUENCE

Protein Sequence (FASTA)
1     VLSADALLAD  LESTTSHISK  RPVFLSEETP  YSYPTGNHTY  QEIAVPPPIP  PPPSSEALNG  60
61    TILDPLDQWQ  PSASRFIHQQ  PQSPSPVYDS  GAKTSSASVP  QDGAGPPCSR  AGEEEHVYSF  120
121   PNKQKSAEPS  PTVMSSSLGS  NLSELDRLLL  ELNAVQHNPP  GFPADEANSS  PPLPGALSPH  180
181   YGIPENNSPL  GGKAGPLMKE  KPKRNGGRGL  EDVRPSVESL  LDELESSVPS  PVPAITVNQG  240
241   EMSSPQRVTS  SQQQTRISAS  SATRELDELM  ASLSDFKIQG  LEQMADGEAW  AAGWPPNDRQ  300
301   SSPEGQDEGG  FMAQGKTGSS  SPPGGPLKPG  SQLDSMLGSL  QSDLNKLGVA  TVAKGVCGAC  360
361   KKPIAGQVVT  AMGKTWHPEH  FVCTHCQEEI  GSRNFFERDG  QPYCEKDYHN  LFSPRCYYCN  420
421   GPILDKVVTA  LDRTWHPEHF  FCAQCGAFFG  PEGFHEKDGK  AYCRKDYFDM  FAPKCGGCAR  480
481   AILENYISAL  NTLWHPECFV  CRECFTPFVN  GSFFEHDGQP  YCEVHYHERR  GSLCSGCQKP  540
541   ITGRCITAMA  KKFHPEHFVC  AFCLKQLNKG  TFKEQNDKPY  CQNCFLKLFC  590
Nucleotide CDS Sequence (FASTA)
1     GTTCTCTCTG  CAGACGCCCT  GCTGGCAGAC  TTGGAGTCCA  CCACCTCCCA  CATCTCCAAA  60
61    CGGCCCGTGT  TCTTGTCCGA  GGAGACCCCC  TACTCATACC  CAACTGGAAA  CCACACATAC  120
121   CAGGAGATTG  CCGTGCCACC  CCCTATCCCG  CCGCCGCCGT  CCAGTGAGGC  CCTCAATGGC  180
181   ACGATCCTTG  ACCCCTTAGA  CCAGTGGCAG  CCCAGTGCCT  CCAGATTTAT  CCACCAGCAG  240
241   CCTCAGTCCC  CGTCACCCGT  GTACGACTCT  GGTGCCAAAA  CTTCCAGTGC  CTCTGTCCCT  300
301   CAGGACGGCG  CAGGCCCTCC  GTGTTCCCGA  GCCGGTGAGG  AAGAGCACGT  CTACAGTTTT  360
361   CCCAATAAGC  AGAAGTCGGC  TGAGCCTTCA  CCCACGGTGA  TGAGCTCCTC  CCTGGGCAGC  420
421   AACCTTTCTG  AACTTGACCG  CCTGCTGCTG  GAACTGAACG  CGGTGCAGCA  TAACCCCCCA  480
481   GGCTTCCCTG  CAGATGAGGC  CAACTCGAGC  CCCCCGCTGC  CTGGGGCTCT  GAGCCCCCAC  540
541   TATGGCATCC  CGGAGAATAA  CAGCCCACTG  GGGGGCAAAG  CCGGGCCCCT  GATGAAAGAG  600
601   AAGCCCAAGC  GGAATGGGGG  CCGCGGGCTG  GAGGATGTGC  GGCCCAGCGT  GGAGAGTCTC  660
661   TTGGATGAAC  TGGAGAGCTC  CGTGCCCAGC  CCCGTCCCTG  CCATCACTGT  GAACCAGGGC  720
721   GAGATGAGCA  GCCCTCAGCG  AGTCACCTCC  AGTCAGCAGC  AGACACGTAT  CTCAGCCTCC  780
781   TCTGCCACCA  GGGAGCTGGA  CGAGCTGATG  GCCTCCCTTT  CGGATTTCAA  GATCCAGGGC  840
841   CTGGAACAAA  TGGCGGATGG  AGAAGCGTGG  GCGGCCGGCT  GGCCTCCGAA  CGACAGGCAG  900
901   AGCAGTCCCG  AAGGGCAGGA  CGAGGGAGGG  TTCATGGCCC  AGGGGAAGAC  GGGGAGCAGC  960
961   TCTCCCCCTG  GGGGGCCCCT  GAAGCCTGGG  AGCCAGCTGG  ATAGTATGCT  GGGGAGCCTG  1020
1021  CAGTCTGACC  TGAACAAACT  GGGGGTCGCC  ACGGTTGCCA  AAGGAGTCTG  CGGGGCCTGC  1080
1081  AAGAAGCCCA  TTGCCGGGCA  GGTCGTGACT  GCCATGGGAA  AGACGTGGCA  CCCGGAGCAC  1140
1141  TTCGTCTGCA  CCCATTGCCA  AGAGGAGATC  GGATCCCGGA  ACTTCTTCGA  GCGGGATGGA  1200
1201  CAGCCCTACT  GTGAAAAGGA  CTATCACAAC  CTCTTCTCTC  CGCGCTGTTA  CTACTGCAAC  1260
1261  GGTCCCATCC  TGGATAAAGT  GGTGACAGCC  CTTGACCGGA  CGTGGCACCC  CGAGCACTTC  1320
1321  TTCTGCGCCC  AGTGTGGAGC  CTTCTTTGGT  CCCGAAGGGT  TCCATGAGAA  AGACGGCAAG  1380
1381  GCCTACTGCC  GGAAGGATTA  CTTTGACATG  TTCGCACCCA  AGTGTGGCGG  CTGTGCCCGG  1440
1441  GCCATCCTGG  AGAACTACAT  CTCGGCCCTC  AACACTCTCT  GGCATCCTGA  ATGCTTTGTG  1500
1501  TGCCGGGAGT  GCTTCACGCC  CTTCGTCAAC  GGCAGCTTCT  TCGAGCACGA  CGGGCAGCCC  1560
1561  TACTGTGAGG  TGCACTACCA  CGAGCGGCGA  GGCTCACTCT  GCTCCGGCTG  CCAGAAGCCC  1620
1621  ATTACGGGCC  GCTGCATCAC  CGCCATGGCC  AAGAAGTTCC  ACCCGGAGCA  CTTCGTCTGT  1680
1681  GCCTTCTGCC  TCAAGCAGCT  CAACAAGGGC  ACCTTCAAGG  AGCAGAACGA  CAAGCCTTAC  1740
1741  TGTCAGAACT  GCTTCCTCAA  GCTCTTCTGC  TAG  1773

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-1946Ursus maritimus98.730.0 660
LLPS-Sah-2697Sarcophilus harrisii98.570.0 566
LLPS-Mup-2403Mustela putorius furo98.470.01061
LLPS-Fec-0520Felis catus98.410.0 654
LLPS-Eqc-1389Equus caballus97.470.0 647
LLPS-Caf-0233Canis familiaris97.460.01054
LLPS-Poa-2082Pongo abelii97.172e-70 238
LLPS-Gog-0813Gorilla gorilla96.520.0 637
LLPS-Maf-1886Macaca fascicularis96.20.0 637
LLPS-Cea-4435Cercocebus atys96.20.0 637
LLPS-Paa-1342Papio anubis96.20.0 637
LLPS-Mal-3031Mandrillus leucophaeus96.20.0 635
LLPS-Pat-3558Pan troglodytes96.20.0 635
LLPS-Pap-1049Pan paniscus96.20.0 636
LLPS-Hos-1725Homo sapiens96.20.0 635
LLPS-Rhb-4661Rhinopithecus bieti96.20.0 637
LLPS-Nol-3120Nomascus leucogenys95.920.0 638
LLPS-Caj-1539Callithrix jacchus95.890.0 634
LLPS-Man-0483Macaca nemestrina95.890.0 630
LLPS-Leo-2972Lepisosteus oculatus95.813e-116 349
LLPS-Mam-2617Macaca mulatta95.690.01024
LLPS-Aon-0125Aotus nancymaae95.570.0 634
LLPS-Tut-0630Tursiops truncatus95.491e-132 410
LLPS-Chs-3577Chlorocebus sabaeus95.170.01020
LLPS-Gaga-3536Gallus gallus95.020.0 583
LLPS-Otg-3739Otolemur garnettii94.660.0 996
LLPS-Lac-3465Latimeria chalumnae94.640.0 581
LLPS-Scm-1826Scophthalmus maximus94.570.0 559
LLPS-Mum-4146Mus musculus94.140.0 995
LLPS-Fud-2725Fukomys damarensis93.790.0 971
LLPS-Bot-2493Bos taurus93.460.0 994
LLPS-Cap-3433Cavia porcellus93.450.0 961
LLPS-Myl-2865Myotis lucifugus93.10.0 994
LLPS-Orl-3907Oryzias latipes93.020.0 560
LLPS-Ova-3303Ovis aries92.780.0 976
LLPS-Mea-2257Mesocricetus auratus92.760.0 992
LLPS-Xim-2282Xiphophorus maculatus91.860.0 550
LLPS-Orc-1653Oryctolagus cuniculus91.190.0 957
LLPS-Dio-1618Dipodomys ordii91.020.0 941
LLPS-Loa-4292Loxodonta africana90.890.0 947
LLPS-Ict-0727Ictidomys tridecemlineatus90.590.0 748
LLPS-Sus-0817Sus scrofa89.980.0 933
LLPS-Anp-1653Anas platyrhynchos86.570.0 909
LLPS-Tag-0713Taeniopygia guttata85.860.0 888
LLPS-Ora-2508Ornithorhynchus anatinus85.740.0 874
LLPS-Mod-0146Monodelphis domestica84.740.0 849
LLPS-Ran-2142Rattus norvegicus84.540.0 889
LLPS-Fia-2959Ficedula albicollis84.480.0 857
LLPS-Meg-1234Meleagris gallopavo84.140.0 887
LLPS-Anc-2974Anolis carolinensis81.90.0 850
LLPS-Pes-2365Pelodiscus sinensis80.930.0 813
LLPS-Xet-2260Xenopus tropicalis74.180.0 755
LLPS-Scf-4063Scleropages formosus69.310.0 699
LLPS-Icp-0948Ictalurus punctatus69.110.0 605
LLPS-Orn-1343Oreochromis niloticus68.690.0 676
LLPS-Dar-0235Danio rerio68.10.0 683
LLPS-Ten-1242Tetraodon nigroviridis67.130.0 677
LLPS-Gaa-3580Gasterosteus aculeatus66.720.0 660
LLPS-Asm-0080Astyanax mexicanus66.440.0 652
LLPS-Pof-4104Poecilia formosa66.090.0 657
LLPS-Tar-1003Takifugu rubripes65.860.0 650
LLPS-Cis-0627Ciona savignyi60.934e-150 448
LLPS-Cii-0690Ciona intestinalis60.591e-147 439
LLPS-Cae-1248Caenorhabditis elegans53.76e-102 322
LLPS-Asni-0817Aspergillus niger43.892e-37 147
LLPS-Ast-0996Aspergillus terreus40.596e-34 141
LLPS-Crn-0147Cryptococcus neoformans39.683e-0654.3
LLPS-Asc-1074Aspergillus clavatus39.115e-33 139
LLPS-Nef-0071Neosartorya fischeri38.615e-32 135
LLPS-Asfu-1221Aspergillus fumigatus38.613e-32 136
LLPS-Spr-0203Sporisorium reilianum37.91e-38 156
LLPS-Usm-1142Ustilago maydis36.943e-39 158
LLPS-Tum-1534Tuber melanosporum36.711e-30 131
LLPS-Pug-0994Puccinia graminis35.052e-31 132