• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pat-3455
MTHFD2L

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: MTHFD2L isoform 7
Gene Name: MTHFD2L, CK820_G0003490
Ensembl Gene: ENSPTRG00000016164.6
Ensembl Protein: ENSPTRP00000070770.1
Organism: Pan troglodytes
Taxa ID: 9598
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTVPVRGFSL  LRGRLGRAPA  LGRSTAPSVR  APGEPGSAFR  GFRSSGVRHE  AIIISGTEIA  60
61    KHIQKEIQRD  VESWVSLGNR  RPHLSIILVG  DNPASHTYVR  NKIRAASAVG  ICSELILKPK  120
121   DVSQEELLDI  TDQLNMDPRV  SGILVQLPLP  DHVDERTICN  GIAPEKDVDG  FHIINIGRLC  180
181   LDQHSLIPAT  ASAVWEIIKR  TGIQTFGKNV  VVAGRSKNVG  MPIAMLLHTD  GEHERPGGDA  240
241   TVTIAHRYTP  KEQLKIHTQL  ADIIIVAAGI  PKLITSDMVK  EGAAVIDVGI  NYVHDPVTGK  300
301   TKLVGDVDFE  AVKKKAGFIT  PVPGGVGPMT  VAMLLKNTLL  AAKKIIY  347
Nucleotide CDS Sequence (FASTA)
1     ATGGACCCAA  GAGTCAGTGG  TATATTAGTT  CAGTTACCAC  TACCAGACCA  CGTTGATGAG  60
61    CGAACAATAT  GCAATGGAAT  TGCCCCAGAA  AAAGATGTAG  ATGGATTTCA  TATTATCAAT  120
121   ATTGGAAGAT  TGTGCCTTGA  TCAGCATTCT  CTCATACCTG  CCACTGCCAG  TGCTGTTTGG  180
181   GAAATAATAA  AAAGAACAGG  AATTCAAACA  TTTGGAAAAA  ATGTGGTTGT  GGCTGGAAGA  240
241   TCCAAGAACG  TAGGGATGCC  TATTGCCATG  CTTTTACACA  CTGATGGAGA  GCATGAACGG  300
301   CCAGGAGGTG  ATGCAACTGT  GACAATAGCT  CACAGATACA  CCCCCAAAGA  GCAACTGAAG  360
361   ATTCATACGC  AGCTGGCAGA  TATTATCATA  GTTGCTGCAG  AGAGATTTCA  CCATTTTGCC  420
421   CAGGACCTCT  CCAACTCCTG  A  441

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-2440Pongo abelii100.01e-137 397
LLPS-Pap-2810Pan paniscus100.00.0 658
LLPS-Hos-2779Homo sapiens99.140.0 654
LLPS-Gog-3356Gorilla gorilla98.660.0 597
LLPS-Nol-1416Nomascus leucogenys97.840.0 647
LLPS-Cas-1286Carlito syrichta97.741e-89 272
LLPS-Rhb-3335Rhinopithecus bieti97.410.0 645
LLPS-Chs-4671Chlorocebus sabaeus96.830.0 647
LLPS-Caf-2369Canis familiaris96.540.0 570
LLPS-Paa-0544Papio anubis96.540.0 640
LLPS-Man-2169Macaca nemestrina96.30.0 635
LLPS-Mam-1905Macaca mulatta96.250.0 638
LLPS-Mal-0706Mandrillus leucophaeus96.250.0 640
LLPS-Cea-2995Cercocebus atys96.250.0 642
LLPS-Caj-4497Callithrix jacchus95.990.0 633
LLPS-Aon-0937Aotus nancymaae95.680.0 631
LLPS-Mup-1191Mustela putorius furo95.50.0 566
LLPS-Aim-3826Ailuropoda melanoleuca94.820.0 604
LLPS-Urm-3305Ursus maritimus94.120.0 561
LLPS-Eqc-3849Equus caballus94.092e-146 430
LLPS-Otg-2799Otolemur garnettii94.00.0 578
LLPS-Fec-3952Felis catus93.730.0 611
LLPS-Loa-2570Loxodonta africana93.670.0 577
LLPS-Ova-3939Ovis aries93.080.0 555
LLPS-Orc-1326Oryctolagus cuniculus92.740.0 609
LLPS-Bot-4553Bos taurus92.110.0 602
LLPS-Ict-2419Ictidomys tridecemlineatus91.050.0 606
LLPS-Mum-3752Mus musculus90.60.0 593
LLPS-Sus-2424Sus scrofa90.00.0 544
LLPS-Ran-2092Rattus norvegicus89.310.0 582
LLPS-Mod-1990Monodelphis domestica88.240.0 526
LLPS-Pes-0352Pelodiscus sinensis87.872e-152 437
LLPS-Myl-4437Myotis lucifugus86.960.0 522
LLPS-Fud-3289Fukomys damarensis85.950.0 546
LLPS-Sah-1026Sarcophilus harrisii85.350.0 553
LLPS-Anp-1445Anas platyrhynchos84.292e-164 468
LLPS-Gaga-0866Gallus gallus82.510.0 529
LLPS-Anc-2619Anolis carolinensis81.760.0 511
LLPS-Fia-3572Ficedula albicollis81.370.0 526
LLPS-Xet-0606Xenopus tropicalis78.435e-177 502
LLPS-Lac-2394Latimeria chalumnae78.190.0 511
LLPS-Leo-1518Lepisosteus oculatus74.921e-169 484
LLPS-Tar-2912Takifugu rubripes74.18e-159 456
LLPS-Pof-3781Poecilia formosa73.115e-167 476
LLPS-Xim-3314Xiphophorus maculatus72.799e-167 476
LLPS-Orl-0405Oryzias latipes72.462e-164 470
LLPS-Scm-1071Scophthalmus maximus71.962e-157 452
LLPS-Orn-3292Oreochromis niloticus71.82e-166 475
LLPS-Dio-1385Dipodomys ordii71.85e-159 457
LLPS-Scf-3046Scleropages formosus71.83e-165 472
LLPS-Mea-0861Mesocricetus auratus71.612e-164 470
LLPS-Dar-2198Danio rerio71.483e-165 472
LLPS-Cap-3831Cavia porcellus71.346e-161 462
LLPS-Icp-4137Ictalurus punctatus71.018e-164 469
LLPS-Tag-3182Taeniopygia guttata70.919e-83 257
LLPS-Gaa-2255Gasterosteus aculeatus70.826e-163 466
LLPS-Asm-3406Astyanax mexicanus70.821e-164 471
LLPS-Meg-1684Meleagris gallopavo70.27e-161 460
LLPS-Ten-3062Tetraodon nigroviridis69.679e-153 440
LLPS-Drm-1432Drosophila melanogaster54.769e-107 322
LLPS-Sem-0487Selaginella moellendorffii49.321e-79 252
LLPS-Sob-1014Sorghum bicolor47.994e-76 243
LLPS-Map-0253Magnaporthe poae47.774e-64 224
LLPS-Tra-2005Triticum aestivum47.371e-67 222
LLPS-Nia-0574Nicotiana attenuata47.189e-74 237
LLPS-Sol-1066Solanum lycopersicum47.184e-73 235
LLPS-Org-1888Oryza glaberrima47.162e-73 239
LLPS-Orm-1592Oryza meridionalis46.982e-74 239
LLPS-Orgl-1184Oryza glumaepatula46.985e-74 237
LLPS-Mua-1716Musa acuminata46.821e-71 231
LLPS-Brd-0316Brachypodium distachyon46.89e-72 233
LLPS-Tru-1040Triticum urartu46.797e-68 223
LLPS-Cus-1837Cucumis sativus46.694e-72 235
LLPS-Orr-1650Oryza rufipogon46.646e-73 234
LLPS-Ors-1431Oryza sativa46.646e-73 234
LLPS-Orp-2128Oryza punctata46.642e-72 233
LLPS-Sei-1863Setaria italica46.643e-72 233
LLPS-Orni-2262Oryza nivara46.646e-73 234
LLPS-Yal-0784Yarrowia lipolytica46.642e-65 227
LLPS-Orb-1306Oryza barthii46.646e-73 234
LLPS-Ori-1753Oryza indica46.646e-73 234
LLPS-Amt-1888Amborella trichopoda46.562e-75 241
LLPS-Hea-2000Helianthus annuus46.531e-71 231
LLPS-Glm-2663Glycine max46.335e-72 232
LLPS-Orbr-1681Oryza brachyantha46.317e-72 232
LLPS-Hov-2124Hordeum vulgare46.314e-72 233
LLPS-Bro-2634Brassica oleracea46.156e-72 232
LLPS-Phv-1647Phaseolus vulgaris46.151e-73 236
LLPS-Met-0382Medicago truncatula46.153e-74 238
LLPS-Cogr-1031Colletotrichum graminicola45.865e-64 223
LLPS-Coc-0359Corchorus capsularis45.671e-72 236
LLPS-Pot-1201Populus trichocarpa45.61e-71 232
LLPS-Viv-1717Vitis vinifera45.511e-71 232
LLPS-Via-0722Vigna angularis45.481e-71 231
LLPS-Asfu-1298Aspergillus fumigatus45.453e-62 218
LLPS-Nef-1502Neosartorya fischeri45.452e-62 219
LLPS-Thc-2396Theobroma cacao45.181e-69 226
LLPS-Brn-2091Brassica napus45.11e-70 229
LLPS-Fus-0110Fusarium solani44.933e-62 218
LLPS-Chc-1079Chondrus crispus44.936e-66 217
LLPS-Gag-1502Gaeumannomyces graminis44.863e-62 219
LLPS-Prp-1020Prunus persica44.857e-71 229
LLPS-Mae-2142Manihot esculenta44.855e-72 233
LLPS-Ast-1552Aspergillus terreus44.787e-62 217
LLPS-Brr-3057Brassica rapa44.777e-71 229
LLPS-Beb-0726Beauveria bassiana44.776e-65 227
LLPS-Coo-1353Colletotrichum orbiculare44.672e-63 222
LLPS-Gas-1188Galdieria sulphuraria44.112e-67 220
LLPS-Asf-1589Aspergillus flavus44.094e-63 221
LLPS-Asg-1091Ashbya gossypii43.963e-55 199
LLPS-Fuo-0768Fusarium oxysporum43.924e-61 215
LLPS-Fuv-1126Fusarium verticillioides43.922e-60 213
LLPS-Zem-1635Zea mays43.894e-71 231
LLPS-Trv-1187Trichoderma virens43.854e-59 209
LLPS-Trr-0560Trichoderma reesei43.853e-60 213
LLPS-Art-1436Arabidopsis thaliana43.792e-70 228
LLPS-Osl-0189Ostreococcus lucimarinus43.624e-68 222
LLPS-Zyt-1230Zymoseptoria tritici43.587e-60 212
LLPS-Aso-0383Aspergillus oryzae43.586e-58 206
LLPS-Mao-0031Magnaporthe oryzae43.588e-63 221
LLPS-Spr-0078Sporisorium reilianum43.567e-58 207
LLPS-Arl-0173Arabidopsis lyrata43.466e-71 230
LLPS-Asc-1399Aspergillus clavatus43.432e-59 210
LLPS-Usm-1140Ustilago maydis43.235e-57 204
LLPS-Asn-1266Aspergillus nidulans43.181e-63 223
LLPS-Chr-1469Chlamydomonas reinhardtii43.15e-66 219
LLPS-Scs-0713Sclerotinia sclerotiorum43.14e-60 213
LLPS-Lem-0713Leptosphaeria maculans43.01e-60 215
LLPS-Vir-1497Vigna radiata42.951e-59 199
LLPS-Dac-1359Daucus carota42.529e-64 210
LLPS-Cym-0282Cyanidioschyzon merolae42.422e-59 203
LLPS-Phn-1206Phaeosphaeria nodorum42.394e-59 212
LLPS-Pyt-1056Pyrenophora teres42.326e-54 195
LLPS-Mel-0585Melampsora laricipopulina42.282e-54 196
LLPS-Ved-1029Verticillium dahliae41.841e-57 205
LLPS-Nec-0638Neurospora crassa41.674e-60 214
LLPS-Scp-0866Schizosaccharomyces pombe41.674e-57 204
LLPS-Abg-1275Absidia glauca41.671e-59 211
LLPS-Kop-1040Komagataella pastoris41.561e-61 217
LLPS-Gor-0889Gossypium raimondii41.099e-67 220
LLPS-Dos-0919Dothistroma septosporum40.964e-56 201
LLPS-Blg-1007Blumeria graminis40.883e-60 213
LLPS-Crn-1190Cryptococcus neoformans40.846e-52 190
LLPS-Cii-1940Ciona intestinalis40.596e-56 201
LLPS-Cis-1752Ciona savignyi40.533e-51 187
LLPS-Scj-0687Schizosaccharomyces japonicus40.45e-57 204
LLPS-Scc-1034Schizosaccharomyces cryophilus40.22e-52 191
LLPS-Miv-0389Microbotryum violaceum40.132e-57 206
LLPS-Sac-1213Saccharomyces cerevisiae40.133e-52 190
LLPS-Tum-0936Tuber melanosporum39.195e-55 198