• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Paa-0401
PAK1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Non-specific serine/threonine protein kinase
Gene Name: PAK1
Ensembl Gene: ENSPANG00000018291.3
Ensembl Protein: ENSPANP00000003980.2
Organism: Papio anubis
Taxa ID: 9555
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Chromatin, Centrosome/Spindle pole body, P-body, Stress granule, Postsynaptic density, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSNNGLDIQD  KPPAPPMRNT  STMIGAGSKD  AGTLNHGSKP  LPPNPEEKKK  KDRFYRSILP  60
61    GDKTNKKKEK  ERPEISLPSD  FEHTIHVGFD  AVTGEFTGMP  EQWARLLQTS  NITKSEQKKN  120
121   PQAVLDVLEF  YNSKKTSNSQ  KYMSFTDKSA  EDYNSSNALN  VKAVSETPAV  PPVSEDEDDD  180
181   DDDATPPPVI  APRPEHTKSV  YTRSVIEPLP  VTSTRDVATS  PISPTENNTT  PPDALTRNTE  240
241   KQKKKPKMSD  EEILEKLRSI  VSVGDPKKKY  TRFEKIGQGA  SGTVYTAMDV  ATGQEVAIKQ  300
301   MNLQQQPKKE  LIINEILVMR  ENKNPNIVNY  LDSYLVGDEL  WVVMEYLAGG  SLTDVVTETC  360
361   MDEGQIAAVC  RECLQALEFL  HSNQVIHRDI  KSDNILLGMD  GSVKLTDFGF  CAQITPEQSK  420
421   RSTMVGTPYW  MAPEVVTRKA  YGPKVDIWSL  GIMAIEMIEG  EPPYLNENPL  RALYLIATNG  480
481   TPELQNPEKL  SAIFRDFLNR  CLEMDVEKRG  SAKELLQHQF  LKIAKPLSSL  TPLIAAAKEA  540
541   TKNNH  545
Nucleotide CDS Sequence (FASTA)
1     ATGTCAAATA  ACGGCCTAGA  CATTCAAGAC  AAACCCCCAG  CCCCTCCGAT  GAGAAATACC  60
61    AGCACTATGA  TTGGAGCTGG  CAGCAAAGAT  GCTGGAACCC  TAAACCATGG  TTCTAAACCT  120
121   CTGCCTCCAA  ACCCAGAGGA  GAAGAAAAAG  AAGGACCGAT  TTTACCGATC  CATCTTACCT  180
181   GGAGATAAAA  CAAATAAAAA  GAAAGAGAAA  GAGCGGCCAG  AGATTTCTCT  CCCTTCAGAT  240
241   TTTGAACACA  CAATTCATGT  TGGTTTTGAT  GCTGTCACAG  GGGAGTTTAC  GGGAATGCCA  300
301   GAGCAGTGGG  CCCGCTTGCT  TCAGACATCA  AATATCACTA  AGTCGGAGCA  GAAGAAAAAC  360
361   CCGCAGGCTG  TTCTGGATGT  GTTGGAGTTT  TACAACTCAA  AGAAGACATC  CAACAGCCAG  420
421   AAATACATGA  GCTTTACAGG  TATGAAAACT  AATGTGAAGG  CTGTGTCTGA  GACTCCTGCA  480
481   GTGCCACCAG  TTTCAGAAGA  TGAGGATGAT  GATGATGATG  ATGCTACCCC  ACCACCAGTG  540
541   ATTGCTCCAC  GCCCAGAGCA  CACAAAATCT  GTATACACAC  GGTCTGTGAT  TGAACCACTT  600
601   CCTGTCACTT  CAACTCGGGA  CGTGGCTACA  TCTCCCATTT  CACCTACTGA  AAATAACACC  660
661   ACTCCACCAG  ATGCTTTGAC  CCGGAATACT  GAGAAGCAGA  AGAAGAAGCC  TAAAATGTCT  720
721   GATGAGGAGA  TCTTGGAGAA  ATTACGAAGC  ATAGTGAGTG  TGGGCGATCC  TAAGAAGAAA  780
781   TATACACGGT  TTGAGAAGAT  TGGACAAGGT  GCTTCAGGCA  CCGTGTACAC  TGCAATGGAT  840
841   GTGGCCACAG  GACAGGAGGT  GGCCATTAAG  CAGATGAATC  TTCAGCAGCA  GCCCAAGAAA  900
901   GAGCTGATTA  TTAATGAGAT  CCTGGTCATG  AGGGAAAACA  AGAACCCAAA  CATTGTGAAT  960
961   TACTTGGACA  GTTACCTCGT  GGGAGATGAG  CTATGGGTTG  TTATGGAATA  CTTGGCTGGA  1020
1021  GGCTCCTTGA  CAGACGTGGT  GACAGAAACA  TGCATGGATG  AAGGCCAGAT  TGCAGCTGTG  1080
1081  TGCCGTGAGT  GTCTGCAGGC  TCTGGAGTTT  TTGCATTCGA  ACCAGGTCAT  TCACAGAGAC  1140
1141  ATCAAGAGTG  ACAATATTCT  GTTGGGAATG  GATGGCTCTG  TCAAGCTAAC  TGATTTTGGA  1200
1201  TTCTGTGCAC  AGATAACCCC  AGAGCAGAGC  AAACGGAGCA  CCATGGTGGG  AACCCCATAC  1260
1261  TGGATGGCAC  CAGAGGTTGT  GACACGAAAG  GCCTATGGGC  CCAAGGTTGA  CATCTGGTCC  1320
1321  CTGGGCATCA  TGGCCATCGA  AATGATTGAA  GGGGAGCCTC  CATACCTCAA  TGAAAACCCT  1380
1381  CTGAGAGCCT  TGTACCTCAT  TGCCACCAAT  GGGACCCCAG  AACTTCAGAA  CCCAGAGAAG  1440
1441  CTGTCAGCTA  TCTTCCGGGA  CTTTCTGAAC  CGCTGTCTTG  AGATGGATGT  GGAGAAGAGA  1500
1501  GGTTCAGCTA  AAGAGCTGCT  GCAGCATCAA  TTCCTGAAGA  TTGCCAAGCC  CCTCTCCAGC  1560
1561  CTCACTCCAC  TGATTGCTGC  CGCAAAGGAG  GCAACAAAGA  ACAATCACTA  A  1611

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Man-1754Macaca nemestrina100.00.01038
LLPS-Mal-1307Mandrillus leucophaeus100.00.01038
LLPS-Cea-1695Cercocebus atys100.00.01038
LLPS-Maf-1617Macaca fascicularis100.00.01038
LLPS-Nol-0462Nomascus leucogenys99.820.01036
LLPS-Mam-2739Macaca mulatta99.810.0 979
LLPS-Rhb-0852Rhinopithecus bieti98.850.0 979
LLPS-Hos-2638Homo sapiens98.850.0 980
LLPS-Pat-0476Pan troglodytes98.850.0 980
LLPS-Gog-1340Gorilla gorilla98.850.0 980
LLPS-Caj-2926Callithrix jacchus98.540.01030
LLPS-Chs-0160Chlorocebus sabaeus98.530.01034
LLPS-Poa-0611Pongo abelii98.350.01032
LLPS-Ova-1206Ovis aries97.80.01028
LLPS-Bot-2211Bos taurus97.80.01028
LLPS-Orc-2787Oryctolagus cuniculus97.610.01027
LLPS-Urm-2117Ursus maritimus97.610.01025
LLPS-Fec-2906Felis catus97.610.01025
LLPS-Mum-0985Mus musculus97.610.01025
LLPS-Mup-2846Mustela putorius furo97.430.01024
LLPS-Myl-1790Myotis lucifugus97.430.01022
LLPS-Ran-1487Rattus norvegicus97.430.01022
LLPS-Aon-0662Aotus nancymaae97.330.0 975
LLPS-Cap-0582Cavia porcellus97.250.01019
LLPS-Eqc-0900Equus caballus97.250.01020
LLPS-Fud-2819Fukomys damarensis97.250.01019
LLPS-Aim-0288Ailuropoda melanoleuca97.10.0 964
LLPS-Ict-0593Ictidomys tridecemlineatus97.060.01018
LLPS-Mea-2409Mesocricetus auratus97.050.0 770
LLPS-Cas-1933Carlito syrichta96.940.0 971
LLPS-Otg-1754Otolemur garnettii96.880.01017
LLPS-Sus-2434Sus scrofa96.870.0 849
LLPS-Mod-1144Monodelphis domestica95.970.01010
LLPS-Sah-2290Sarcophilus harrisii95.970.01009
LLPS-Caf-2359Canis familiaris95.230.0 994
LLPS-Pes-1472Pelodiscus sinensis94.690.0 994
LLPS-Anp-0554Anas platyrhynchos94.550.0 879
LLPS-Loa-2757Loxodonta africana94.530.0 980
LLPS-Dio-2194Dipodomys ordii94.520.0 988
LLPS-Anc-0291Anolis carolinensis94.050.0 838
LLPS-Fia-3020Ficedula albicollis94.00.0 881
LLPS-Pap-1685Pan paniscus93.940.0 946
LLPS-Ora-0754Ornithorhynchus anatinus93.380.0 548
LLPS-Tut-2295Tursiops truncatus93.310.0 918
LLPS-Gaga-2646Gallus gallus93.220.0 976
LLPS-Tag-0399Taeniopygia guttata93.040.0 973
LLPS-Lac-1238Latimeria chalumnae88.50.0 932
LLPS-Xim-3853Xiphophorus maculatus85.840.0 636
LLPS-Pof-1579Poecilia formosa84.80.0 875
LLPS-Leo-0387Lepisosteus oculatus83.940.0 868
LLPS-Meg-0658Meleagris gallopavo83.850.0 831
LLPS-Ten-1065Tetraodon nigroviridis83.120.0 854
LLPS-Drm-2255Drosophila melanogaster83.060.0 541
LLPS-Icp-1133Ictalurus punctatus82.590.0 856
LLPS-Tar-0099Takifugu rubripes81.270.0 856
LLPS-Scf-0403Scleropages formosus80.070.0 833
LLPS-Dar-3495Danio rerio79.860.0 861
LLPS-Asm-2692Astyanax mexicanus79.820.0 800
LLPS-Xet-1210Xenopus tropicalis79.740.0 848
LLPS-Gaa-1800Gasterosteus aculeatus79.610.0 843
LLPS-Scm-2012Scophthalmus maximus79.30.0 838
LLPS-Orl-3470Oryzias latipes78.610.0 830
LLPS-Orn-0801Oreochromis niloticus78.190.0 849
LLPS-Cii-0316Ciona intestinalis76.570.0 558
LLPS-Cae-1336Caenorhabditis elegans74.251e-159 474
LLPS-Ast-1039Aspergillus terreus69.174e-123 389
LLPS-Asfu-0363Aspergillus fumigatus67.942e-132 412
LLPS-Asc-1516Aspergillus clavatus67.945e-132 411
LLPS-Trr-0785Trichoderma reesei67.712e-134 417
LLPS-Nef-0386Neosartorya fischeri67.66e-132 411
LLPS-Trv-0879Trichoderma virens67.361e-133 416
LLPS-Asf-1216Aspergillus flavus67.255e-132 412
LLPS-Aso-1366Aspergillus oryzae67.255e-132 412
LLPS-Dos-1365Dothistroma septosporum66.895e-138 422
LLPS-Scs-0838Sclerotinia sclerotiorum66.782e-133 413
LLPS-Miv-0132Microbotryum violaceum66.671e-1790.5
LLPS-Tum-0875Tuber melanosporum66.558e-126 395
LLPS-Asn-0596Aspergillus nidulans66.552e-129 405
LLPS-Phn-0211Phaeosphaeria nodorum66.443e-132 413
LLPS-Lem-0804Leptosphaeria maculans66.443e-132 414
LLPS-Asni-1574Aspergillus niger66.448e-131 409
LLPS-Fuv-0121Fusarium verticillioides66.329e-131 408
LLPS-Fus-1143Fusarium solani65.979e-131 409
LLPS-Beb-1232Beauveria bassiana65.974e-131 410
LLPS-Zyt-0111Zymoseptoria tritici65.871e-136 418
LLPS-Coo-1293Colletotrichum orbiculare65.452e-133 419
LLPS-Pytr-0173Pyrenophora triticirepentis65.051e-130 409
LLPS-Pyt-0362Pyrenophora teres65.052e-130 408
LLPS-Abg-0755Absidia glauca65.03e-145 443
LLPS-Scj-0262Schizosaccharomyces japonicus64.988e-134 412
LLPS-Blg-1502Blumeria graminis64.382e-129 406
LLPS-Asg-1412Ashbya gossypii64.144e-124 394
LLPS-Map-1256Magnaporthe poae63.791e-129 410
LLPS-Gag-1264Gaeumannomyces graminis63.795e-131 412
LLPS-Spr-1285Sporisorium reilianum63.491e-136 424
LLPS-Fuo-0431Fusarium oxysporum63.315e-131 409
LLPS-Usm-0877Ustilago maydis63.162e-1789.7
LLPS-Yal-0672Yarrowia lipolytica62.147e-129 410
LLPS-Scp-1254Schizosaccharomyces pombe60.736e-129 398
LLPS-Scc-1216Schizosaccharomyces cryophilus60.132e-127 395
LLPS-Pug-1422Puccinia graminis59.751e-123 388
LLPS-Sac-0608Saccharomyces cerevisiae59.654e-130 409
LLPS-Mel-1046Melampsora laricipopulina59.528e-131 405
LLPS-Kop-1456Komagataella pastoris59.082e-130 409
LLPS-Crn-0588Cryptococcus neoformans58.637e-128 399
LLPS-Nec-0592Neurospora crassa58.172e-115 368
LLPS-Cis-0735Ciona savignyi57.540.0 628
LLPS-Mao-1239Magnaporthe oryzae57.323e-115 369
LLPS-Cogr-1091Colletotrichum graminicola53.932e-115 369
LLPS-Put-1135Puccinia triticina46.464e-139 426