LLPS-Mup-2846
PAK1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Non-specific serine/threonine protein kinase |
| Gene Name: | PAK1 |
| Ensembl Gene: | ENSMPUG00000015949.1 |
| Ensembl Protein: | ENSMPUP00000015844.1 |
| Organism: | Mustela putorius furo |
| Taxa ID: | 9669 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Chromatin, Centrosome/Spindle pole body, P-body, Stress granule, Postsynaptic density, Others | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMPUT00000016085.1 | ENSMPUP00000015844.1 |
| UniProt | M3YWY4, M3YWY4_MUSPF | |
| GeneBank | AEYP01101474, AEYP01101479, AEYP01101476, AEYP01101477, AEYP01101478, AEYP01101475, AEYP01101480 | |
| RefSeq | XM_004781033.2, XM_013050251.1, XM_013050252.1, XM_013050253.1 | XP_004781090.1, XP_012905705.1, XP_012905706.1, XP_012905707.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSNNGLDIQD KPPAPPMRNT STMIGAGSKD AGTLNHGSKP LPPNPEEKKK KDRFYRSILP 60 61 GDKTNKKKEK ERPEISLPSD FEHTIHVGFD AVTGEFTGMP EQWARLLQTS NITKSEQKKN 120 121 PQAVLDVLEF YNSKKTSNSQ KYMSFTDKSA EDYNSSNTLN VKTVSETPAV PPVSEDEDDD 180 181 DDATPPPVIA PRPEHTKSVY TRSVIEPIPV TPTRDAATSP ISPTENNTTP PDALTRNTEK 240 241 QKKKPKMSDE EILEKLRSIV SVGDPKKKYT RFEKIGQGAS GTVYTAMDVA TGQEVAIKQM 300 301 NLQQQPKKEL IINEILVMRE NKNPNIVNYL DSYLVGDELW VVMEYLAGGS LTDVVTETCM 360 361 DEGQIAAVCR ECLQALEFLH SNQVIHRDIK SDNILLGMDG SVKLTDFGFC AQITPEQSKR 420 421 STMVGTPYWM APEVVTRKAY GPKVDIWSLG IMAIEMIEGE PPYLNENPLR ALYLIATNGT 480 481 PELQNPEKLS AFFRDFLNRC LEMDVEKRGS AKELLQHQFL KIAKPLSSLT PLIAAAKEAT 540 541 KNNH 544 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCAAATA ACGGCCTAGA CATTCAAGAC AAACCCCCAG CCCCTCCAAT GAGAAACACC 60 61 AGCACTATGA TTGGAGCTGG AAGCAAAGAT GCGGGAACCC TAAACCATGG TTCCAAACCT 120 121 CTGCCTCCAA ACCCAGAGGA GAAGAAAAAG AAGGACCGAT TTTACCGATC CATCTTACCT 180 181 GGAGATAAAA CAAATAAAAA GAAGGAGAAG GAACGGCCGG AGATTTCTCT TCCTTCAGAT 240 241 TTTGAGCACA CGATTCACGT TGGTTTTGAT GCTGTCACAG GGGAGTTTAC AGGGATGCCA 300 301 GAGCAATGGG CTCGCCTCCT TCAGACATCA AATATCACTA AGTCAGAGCA GAAGAAAAAC 360 361 CCGCAGGCTG TTCTGGATGT ATTGGAATTT TATAACTCAA AGAAGACTTC CAACAGCCAG 420 421 AAGTACATGA GCTTTACAGA TAAATCAGCT GAGGATTATA ATTCTTCTAA TACATTGAAT 480 481 GTGAAGACAG TGTCTGAGAC CCCTGCAGTG CCACCGGTTT CAGAAGATGA AGATGATGAT 540 541 GATGATGCTA CCCCACCTCC AGTGATTGCT CCACGCCCAG AGCACACAAA ATCTGTATAT 600 601 ACACGGTCTG TGATAGAACC AATTCCTGTT ACTCCAACTC GGGATGCGGC TACATCTCCC 660 661 ATTTCACCTA CTGAGAATAA TACCACTCCA CCAGATGCTC TGACCCGAAA TACTGAGAAG 720 721 CAGAAGAAGA AACCTAAAAT GTCTGATGAG GAGATCTTGG AGAAATTACG GAGCATAGTG 780 781 AGTGTGGGCG ATCCTAAGAA GAAATATACA CGGTTTGAGA AGATTGGACA AGGTGCTTCA 840 841 GGCACTGTGT ACACTGCAAT GGATGTGGCC ACAGGACAGG AGGTGGCCAT TAAGCAGATG 900 901 AACCTTCAGC AGCAGCCGAA GAAAGAGCTG ATTATTAATG AGATCCTGGT CATGAGGGAA 960 961 AACAAGAACC CAAATATTGT GAACTACTTG GACAGTTACC TCGTGGGAGA TGAGCTGTGG 1020 1021 GTTGTCATGG AATACTTGGC TGGAGGTTCT TTGACAGATG TGGTGACAGA AACTTGCATG 1080 1081 GATGAAGGCC AGATTGCAGC TGTCTGCCGT GAGTGCCTAC AGGCTTTGGA GTTTCTGCAT 1140 1141 TCCAACCAGG TCATTCACAG AGACATCAAG AGCGACAACA TCCTGTTGGG AATGGATGGC 1200 1201 TCTGTCAAGC TAACCGATTT CGGGTTCTGT GCACAGATCA CCCCAGAGCA GAGCAAACGG 1260 1261 AGCACCATGG TGGGAACTCC ATACTGGATG GCACCAGAGG TTGTGACGCG GAAGGCCTAT 1320 1321 GGACCCAAGG TTGACATCTG GTCCCTGGGC ATCATGGCCA TCGAAATGAT TGAAGGGGAG 1380 1381 CCCCCATACC TCAATGAAAA TCCTCTGAGA GCCTTGTACC TCATTGCCAC CAATGGGACC 1440 1441 CCAGAGCTTC AGAACCCAGA GAAGCTGTCA GCTTTCTTCC GGGACTTTCT GAACCGCTGT 1500 1501 CTCGAGATGG ATGTGGAGAA GAGAGGTTCA GCTAAAGAGC TGCTGCAGCA TCAGTTCCTG 1560 1561 AAAATTGCCA AGCCCCTCTC CAGCCTCACT CCACTGATTG CTGCAGCAAA GGAGGCAACC 1620 1621 AAGAACAATC ACTAA 1635 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-2117 | Ursus maritimus | 99.82 | 0.0 | 1037 |
| LLPS-Fec-2906 | Felis catus | 99.45 | 0.0 | 1033 |
| LLPS-Aim-0288 | Ailuropoda melanoleuca | 99.42 | 0.0 | 977 |
| LLPS-Mea-2409 | Mesocricetus auratus | 99.26 | 0.0 | 778 |
| LLPS-Mum-0985 | Mus musculus | 99.08 | 0.0 | 1030 |
| LLPS-Orc-2787 | Oryctolagus cuniculus | 99.08 | 0.0 | 1031 |
| LLPS-Otg-1754 | Otolemur garnettii | 99.08 | 0.0 | 1028 |
| LLPS-Ova-1206 | Ovis aries | 98.9 | 0.0 | 1030 |
| LLPS-Myl-1790 | Myotis lucifugus | 98.9 | 0.0 | 1028 |
| LLPS-Ran-1487 | Rattus norvegicus | 98.9 | 0.0 | 1027 |
| LLPS-Chs-0160 | Chlorocebus sabaeus | 98.9 | 0.0 | 1028 |
| LLPS-Bot-2211 | Bos taurus | 98.71 | 0.0 | 1029 |
| LLPS-Fud-2819 | Fukomys damarensis | 98.71 | 0.0 | 1025 |
| LLPS-Eqc-0900 | Equus caballus | 98.71 | 0.0 | 1026 |
| LLPS-Cap-0582 | Cavia porcellus | 98.71 | 0.0 | 1025 |
| LLPS-Sus-2434 | Sus scrofa | 98.65 | 0.0 | 855 |
| LLPS-Ict-0593 | Ictidomys tridecemlineatus | 98.53 | 0.0 | 1023 |
| LLPS-Cas-1933 | Carlito syrichta | 98.47 | 0.0 | 977 |
| LLPS-Poa-0611 | Pongo abelii | 97.99 | 0.0 | 1025 |
| LLPS-Nol-0462 | Nomascus leucogenys | 97.61 | 0.0 | 1025 |
| LLPS-Caj-2926 | Callithrix jacchus | 97.44 | 0.0 | 1023 |
| LLPS-Mal-1307 | Mandrillus leucophaeus | 97.43 | 0.0 | 1024 |
| LLPS-Paa-0401 | Papio anubis | 97.43 | 0.0 | 1024 |
| LLPS-Cea-1695 | Cercocebus atys | 97.43 | 0.0 | 1024 |
| LLPS-Maf-1617 | Macaca fascicularis | 97.43 | 0.0 | 1024 |
| LLPS-Caf-2359 | Canis familiaris | 97.43 | 0.0 | 1007 |
| LLPS-Man-1754 | Macaca nemestrina | 97.43 | 0.0 | 1024 |
| LLPS-Sah-2290 | Sarcophilus harrisii | 97.25 | 0.0 | 1015 |
| LLPS-Mod-1144 | Monodelphis domestica | 97.25 | 0.0 | 1015 |
| LLPS-Mam-2739 | Macaca mulatta | 97.1 | 0.0 | 962 |
| LLPS-Aon-0662 | Aotus nancymaae | 96.95 | 0.0 | 969 |
| LLPS-Gog-1340 | Gorilla gorilla | 96.56 | 0.0 | 969 |
| LLPS-Pat-0476 | Pan troglodytes | 96.56 | 0.0 | 969 |
| LLPS-Hos-2638 | Homo sapiens | 96.56 | 0.0 | 969 |
| LLPS-Rhb-0852 | Rhinopithecus bieti | 96.18 | 0.0 | 963 |
| LLPS-Loa-2757 | Loxodonta africana | 95.8 | 0.0 | 983 |
| LLPS-Dio-2194 | Dipodomys ordii | 95.6 | 0.0 | 992 |
| LLPS-Anp-0554 | Anas platyrhynchos | 95.38 | 0.0 | 882 |
| LLPS-Anc-0291 | Anolis carolinensis | 95.36 | 0.0 | 840 |
| LLPS-Pes-1472 | Pelodiscus sinensis | 95.05 | 0.0 | 994 |
| LLPS-Tut-2295 | Tursiops truncatus | 94.83 | 0.0 | 924 |
| LLPS-Fia-3020 | Ficedula albicollis | 94.81 | 0.0 | 884 |
| LLPS-Gaga-2646 | Gallus gallus | 93.94 | 0.0 | 979 |
| LLPS-Tag-0399 | Taeniopygia guttata | 93.76 | 0.0 | 976 |
| LLPS-Ora-0754 | Ornithorhynchus anatinus | 93.38 | 0.0 | 546 |
| LLPS-Pap-1685 | Pan paniscus | 91.74 | 0.0 | 936 |
| LLPS-Lac-1238 | Latimeria chalumnae | 89.21 | 0.0 | 936 |
| LLPS-Scm-0956 | Scophthalmus maximus | 86.4 | 0.0 | 640 |
| LLPS-Xim-3853 | Xiphophorus maculatus | 86.12 | 0.0 | 638 |
| LLPS-Meg-0658 | Meleagris gallopavo | 84.74 | 0.0 | 832 |
| LLPS-Pof-1579 | Poecilia formosa | 84.59 | 0.0 | 870 |
| LLPS-Leo-0387 | Lepisosteus oculatus | 84.09 | 0.0 | 867 |
| LLPS-Ten-1065 | Tetraodon nigroviridis | 83.46 | 0.0 | 853 |
| LLPS-Drm-2255 | Drosophila melanogaster | 83.06 | 0.0 | 541 |
| LLPS-Icp-1133 | Ictalurus punctatus | 82.91 | 0.0 | 857 |
| LLPS-Tar-0099 | Takifugu rubripes | 81.06 | 0.0 | 857 |
| LLPS-Asm-2692 | Astyanax mexicanus | 80.51 | 0.0 | 800 |
| LLPS-Xet-1210 | Xenopus tropicalis | 80.44 | 0.0 | 853 |
| LLPS-Scf-0403 | Scleropages formosus | 80.43 | 0.0 | 837 |
| LLPS-Gaa-1800 | Gasterosteus aculeatus | 80.11 | 0.0 | 844 |
| LLPS-Orl-3470 | Oryzias latipes | 78.75 | 0.0 | 825 |
| LLPS-Dar-3495 | Danio rerio | 78.51 | 0.0 | 853 |
| LLPS-Orn-0801 | Oreochromis niloticus | 78.5 | 0.0 | 849 |
| LLPS-Cii-0316 | Ciona intestinalis | 76.29 | 0.0 | 556 |
| LLPS-Ast-1039 | Aspergillus terreus | 69.17 | 1e-122 | 387 |
| LLPS-Cae-1336 | Caenorhabditis elegans | 68.84 | 5e-160 | 475 |
| LLPS-Asfu-0363 | Aspergillus fumigatus | 67.94 | 1e-131 | 410 |
| LLPS-Trr-0785 | Trichoderma reesei | 67.71 | 1e-133 | 416 |
| LLPS-Asc-1516 | Aspergillus clavatus | 67.6 | 2e-131 | 410 |
| LLPS-Nef-0386 | Neosartorya fischeri | 67.6 | 3e-131 | 409 |
| LLPS-Trv-0879 | Trichoderma virens | 67.36 | 6e-133 | 414 |
| LLPS-Asf-1216 | Aspergillus flavus | 67.25 | 3e-131 | 410 |
| LLPS-Aso-1366 | Aspergillus oryzae | 67.25 | 3e-131 | 410 |
| LLPS-Dos-1365 | Dothistroma septosporum | 66.89 | 1e-137 | 421 |
| LLPS-Scs-0838 | Sclerotinia sclerotiorum | 66.78 | 1e-132 | 410 |
| LLPS-Miv-0132 | Microbotryum violaceum | 66.67 | 2e-17 | 90.5 |
| LLPS-Tum-0875 | Tuber melanosporum | 66.55 | 1e-125 | 395 |
| LLPS-Asn-0596 | Aspergillus nidulans | 66.55 | 8e-129 | 404 |
| LLPS-Lem-0804 | Leptosphaeria maculans | 66.44 | 1e-131 | 412 |
| LLPS-Asni-1574 | Aspergillus niger | 66.44 | 3e-130 | 407 |
| LLPS-Phn-0211 | Phaeosphaeria nodorum | 66.44 | 6e-132 | 412 |
| LLPS-Sac-0608 | Saccharomyces cerevisiae | 66.32 | 8e-130 | 409 |
| LLPS-Fus-1143 | Fusarium solani | 65.97 | 1e-130 | 409 |
| LLPS-Beb-1232 | Beauveria bassiana | 65.97 | 1e-130 | 409 |
| LLPS-Zyt-0111 | Zymoseptoria tritici | 65.87 | 5e-136 | 416 |
| LLPS-Coo-1293 | Colletotrichum orbiculare | 65.45 | 6e-133 | 418 |
| LLPS-Pyt-0362 | Pyrenophora teres | 65.05 | 5e-130 | 407 |
| LLPS-Pytr-0173 | Pyrenophora triticirepentis | 65.05 | 4e-130 | 407 |
| LLPS-Abg-0755 | Absidia glauca | 65.0 | 1e-144 | 441 |
| LLPS-Scj-0262 | Schizosaccharomyces japonicus | 64.98 | 3e-133 | 410 |
| LLPS-Blg-1502 | Blumeria graminis | 64.38 | 4e-129 | 405 |
| LLPS-Asg-1412 | Ashbya gossypii | 64.14 | 1e-123 | 393 |
| LLPS-Map-1256 | Magnaporthe poae | 63.79 | 5e-129 | 408 |
| LLPS-Gag-1264 | Gaeumannomyces graminis | 63.79 | 2e-130 | 411 |
| LLPS-Spr-1285 | Sporisorium reilianum | 63.49 | 2e-136 | 424 |
| LLPS-Fuv-0121 | Fusarium verticillioides | 63.31 | 4e-130 | 406 |
| LLPS-Fuo-0431 | Fusarium oxysporum | 63.31 | 3e-130 | 407 |
| LLPS-Usm-0877 | Ustilago maydis | 63.16 | 3e-17 | 89.7 |
| LLPS-Kop-1456 | Komagataella pastoris | 62.17 | 3e-130 | 408 |
| LLPS-Yal-0672 | Yarrowia lipolytica | 61.81 | 5e-128 | 408 |
| LLPS-Scp-1254 | Schizosaccharomyces pombe | 60.73 | 3e-128 | 397 |
| LLPS-Scc-1216 | Schizosaccharomyces cryophilus | 60.13 | 6e-127 | 393 |
| LLPS-Mel-1046 | Melampsora laricipopulina | 60.12 | 2e-130 | 405 |
| LLPS-Pug-1422 | Puccinia graminis | 59.75 | 1e-123 | 388 |
| LLPS-Crn-0588 | Cryptococcus neoformans | 59.21 | 2e-127 | 398 |
| LLPS-Put-1135 | Puccinia triticina | 58.82 | 4e-18 | 92.0 |
| LLPS-Nec-0592 | Neurospora crassa | 58.17 | 2e-115 | 368 |
| LLPS-Cis-0735 | Ciona savignyi | 57.4 | 0.0 | 629 |
| LLPS-Cogr-1091 | Colletotrichum graminicola | 54.21 | 5e-117 | 373 |
| LLPS-Mao-1239 | Magnaporthe oryzae | 52.32 | 2e-116 | 371 |