• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ova-4236
ALDH5A1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Succinate-semialdehyde dehydrogenase
Gene Name: ALDH5A1
Ensembl Gene: ENSOARG00000006546.1
Ensembl Protein: ENSOARP00000007008.1
Organism: Ovis aries
Taxa ID: 9940
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSOART00000007115.1ENSOARP00000007008.1
UniProtW5P9A0, W5P9A0_SHEEP
GeneBankAMGL01059253

▼ SEQUENCE

Protein Sequence (FASTA)
1     LVADCGVPGA  RAAVRAAYEA  FCSWRGVSAK  ERSSLLRKWY  DLMIQNKDDL  AKIITAESGK  60
61    PLKEAQGEIL  YSANFLEWFS  EEARRVYGDI  ISTPTKERRA  FVLKQPLGVA  AVITPWNFPS  120
121   AMITRKVGAA  LAAGCTVVVK  PAEDTPFSAL  ALGELANQAG  IPPGVYNVIP  CSQKKAKEVG  180
181   EALCTDPLVS  KISFTGSTAT  GKVLLHHAAN  SVKRVSMELG  GHAPFIVFDS  ANVDQAVAGA  240
241   MASKFRNSGQ  TCVCSNRFLV  QSGIHDSFVK  KFAEAIETNL  HVGNGFEERT  TQGPLINAKA  300
301   VEKVEKHVHD  AISKGATVVT  GGKRHHVGKN  FFEPTLLSNV  TRDMLCSQEE  TFGPVAPVIK  360
361   FNTEEEAVAI  ANAADVGLAG  YFYSQDPAQI  WRVAERLEVG  MVGVNEGLIS  SVECPFGGVK  420
421   QSGLGREGSK  YGIDEYLELK  YVCFGGL  447
Nucleotide CDS Sequence (FASTA)
1     TTGGTGGCCG  ACTGCGGGGT  GCCGGGGGCC  CGCGCGGCCG  TGCGCGCTGC  CTACGAGGCT  60
61    TTCTGCAGCT  GGAGGGGGGT  CTCGGCCAAG  GAGAGGAGTT  CTTTACTTCG  CAAGTGGTAT  120
121   GACTTAATGA  TACAAAATAA  GGATGACCTT  GCCAAGATAA  TTACAGCTGA  AAGTGGAAAG  180
181   CCACTGAAGG  AGGCACAGGG  AGAAATTCTC  TATTCTGCCA  ACTTCCTGGA  GTGGTTTTCA  240
241   GAGGAAGCCC  GCCGTGTTTA  CGGAGACATT  ATCTCCACTC  CAACAAAAGA  AAGGCGGGCT  300
301   TTCGTCCTCA  AGCAGCCCCT  CGGGGTGGCC  GCCGTCATCA  CCCCGTGGAA  TTTTCCCAGC  360
361   GCCATGATCA  CGCGGAAGGT  GGGGGCCGCC  CTGGCAGCCG  GCTGCACGGT  GGTGGTTAAA  420
421   CCTGCTGAGG  ACACGCCCTT  CTCCGCCCTG  GCCTTGGGTG  AGCTTGCAAA  CCAGGCTGGA  480
481   ATTCCCCCAG  GTGTGTACAA  CGTGATTCCT  TGCTCTCAAA  AGAAGGCCAA  GGAAGTAGGG  540
541   GAAGCACTTT  GTACAGATCC  TCTCGTGTCT  AAAATTTCCT  TTACTGGTTC  AACAGCCACT  600
601   GGAAAGGTCC  TATTGCACCA  CGCAGCAAAC  TCTGTGAAGA  GGGTGTCCAT  GGAGCTGGGT  660
661   GGCCATGCCC  CTTTCATCGT  CTTTGACAGT  GCCAATGTGG  ACCAGGCTGT  CGCCGGGGCC  720
721   ATGGCCTCCA  AATTTAGGAA  CTCTGGACAG  ACGTGTGTGT  GCTCCAACCG  TTTCTTGGTG  780
781   CAAAGCGGTA  TCCATGACTC  CTTTGTGAAA  AAATTTGCTG  AGGCAATTGA  AACGAACCTG  840
841   CATGTGGGTA  ATGGATTTGA  AGAGAGAACT  ACTCAAGGCC  CGTTAATTAA  TGCAAAAGCT  900
901   GTAGAAAAGG  TAGAGAAACA  CGTGCATGAT  GCCATTTCCA  AGGGGGCCAC  CGTCGTGACA  960
961   GGTGGGAAGC  GACACCACGT  TGGGAAAAAT  TTCTTCGAGC  CCACCCTGCT  CAGCAACGTC  1020
1021  ACCCGAGACA  TGCTCTGCTC  TCAGGAAGAG  ACTTTTGGGC  CTGTGGCACC  TGTTATCAAG  1080
1081  TTCAACACAG  AGGAGGAGGC  AGTGGCGATC  GCTAACGCGG  CCGACGTCGG  GCTGGCAGGT  1140
1141  TATTTTTACT  CTCAAGACCC  GGCCCAGATC  TGGAGGGTGG  CGGAGCGGCT  GGAGGTCGGC  1200
1201  ATGGTTGGCG  TTAACGAAGG  ACTGATCTCC  TCCGTGGAGT  GCCCTTTTGG  GGGGGTGAAG  1260
1261  CAGTCCGGCC  TTGGGCGAGA  GGGCTCCAAG  TACGGCATTG  ACGAGTATCT  GGAGCTCAAG  1320
1321  TATGTGTGCT  TCGGAGGCTT  ATAG  1344

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Bot-1124Bos taurus97.990.0 851
LLPS-Tut-1900Tursiops truncatus95.750.0 836
LLPS-Sus-4136Sus scrofa93.740.0 815
LLPS-Caf-3955Canis familiaris93.070.0 779
LLPS-Fec-3193Felis catus93.050.0 837
LLPS-Urm-3944Ursus maritimus92.310.0 825
LLPS-Eqc-4781Equus caballus92.260.0 820
LLPS-Cap-3349Cavia porcellus90.650.0 785
LLPS-Aon-4135Aotus nancymaae90.380.0 792
LLPS-Caj-4578Callithrix jacchus89.930.0 790
LLPS-Otg-4727Otolemur garnettii89.930.0 814
LLPS-Orc-3634Oryctolagus cuniculus89.910.0 809
LLPS-Chs-1378Chlorocebus sabaeus89.710.0 818
LLPS-Maf-0189Macaca fascicularis89.710.0 816
LLPS-Cea-3446Cercocebus atys89.710.0 816
LLPS-Mam-4109Macaca mulatta89.710.0 816
LLPS-Loa-3559Loxodonta africana89.580.0 778
LLPS-Rhb-4382Rhinopithecus bieti89.550.0 800
LLPS-Mal-4524Mandrillus leucophaeus89.490.0 814
LLPS-Man-1468Macaca nemestrina89.490.0 815
LLPS-Poa-4291Pongo abelii89.490.0 778
LLPS-Paa-1387Papio anubis89.260.0 811
LLPS-Nol-3639Nomascus leucogenys89.260.0 776
LLPS-Ran-0495Rattus norvegicus88.570.0 795
LLPS-Cas-3494Carlito syrichta88.430.0 763
LLPS-Mum-3573Mus musculus88.340.0 789
LLPS-Mea-3745Mesocricetus auratus88.250.0 609
LLPS-Fud-4075Fukomys damarensis88.080.0 783
LLPS-Myl-4237Myotis lucifugus88.040.0 779
LLPS-Sah-2527Sarcophilus harrisii87.890.0 804
LLPS-Ict-3355Ictidomys tridecemlineatus87.020.0 787
LLPS-Pap-0197Pan paniscus86.740.0 765
LLPS-Dio-2936Dipodomys ordii86.570.0 783
LLPS-Gog-3741Gorilla gorilla86.520.0 765
LLPS-Hos-1667Homo sapiens86.520.0 764
LLPS-Pat-4613Pan troglodytes86.520.0 763
LLPS-Anp-2402Anas platyrhynchos82.540.0 712
LLPS-Pes-3683Pelodiscus sinensis82.540.0 716
LLPS-Anc-3722Anolis carolinensis81.840.0 741
LLPS-Fia-0111Ficedula albicollis81.710.0 713
LLPS-Xet-2846Xenopus tropicalis80.940.0 717
LLPS-Gaga-2600Gallus gallus80.490.0 723
LLPS-Tag-2835Taeniopygia guttata80.490.0 715
LLPS-Mod-2720Monodelphis domestica78.920.0 709
LLPS-Meg-3046Meleagris gallopavo78.640.0 570
LLPS-Lac-3805Latimeria chalumnae78.030.0 691
LLPS-Asm-1363Astyanax mexicanus74.220.0 667
LLPS-Orn-2917Oreochromis niloticus73.780.0 588
LLPS-Leo-1253Lepisosteus oculatus73.320.0 655
LLPS-Dar-2239Danio rerio73.320.0 683
LLPS-Pof-2496Poecilia formosa73.320.0 601
LLPS-Icp-1851Ictalurus punctatus73.090.0 654
LLPS-Scf-0234Scleropages formosus72.90.0 638
LLPS-Xim-1113Xiphophorus maculatus72.420.0 604
LLPS-Orl-3068Oryzias latipes71.30.0 644
LLPS-Tar-1463Takifugu rubripes71.30.0 639
LLPS-Ten-2485Tetraodon nigroviridis70.180.0 629
LLPS-Scm-1181Scophthalmus maximus69.632e-154 448
LLPS-Pot-0905Populus trichocarpa61.630.0 536
LLPS-Cus-0703Cucumis sativus61.40.0 550
LLPS-Art-2504Arabidopsis thaliana61.40.0 537
LLPS-Thc-2154Theobroma cacao61.160.0 533
LLPS-Zem-1986Zea mays61.160.0 531
LLPS-Mua-1846Musa acuminata60.874e-141 415
LLPS-Coc-1896Corchorus capsularis60.854e-180 521
LLPS-Sob-1449Sorghum bicolor60.70.0 528
LLPS-Mae-2421Manihot esculenta60.70.0 549
LLPS-Amt-0664Amborella trichopoda60.70.0 551
LLPS-Prp-1254Prunus persica60.70.0 545
LLPS-Tra-2052Triticum aestivum60.661e-179 520
LLPS-Arl-2000Arabidopsis lyrata60.470.0 527
LLPS-Nec-0663Neurospora crassa60.370.0 534
LLPS-Gor-2658Gossypium raimondii60.330.0 532
LLPS-Brd-1084Brachypodium distachyon60.231e-180 523
LLPS-Php-1916Physcomitrella patens60.140.0 530
LLPS-Glm-0594Glycine max60.00.0 545
LLPS-Sei-0219Setaria italica60.00.0 526
LLPS-Aso-1203Aspergillus oryzae59.860.0 523
LLPS-Brr-1196Brassica rapa59.770.0 527
LLPS-Viv-2362Vitis vinifera59.770.0 523
LLPS-Phv-1203Phaseolus vulgaris59.772e-145 426
LLPS-Sem-0586Selaginella moellendorffii59.530.0 538
LLPS-Hea-2366Helianthus annuus59.533e-177 515
LLPS-Nia-1040Nicotiana attenuata59.530.0 543
LLPS-Asni-0948Aspergillus niger59.40.0 525
LLPS-Sol-1705Solanum lycopersicum59.070.0 541
LLPS-Orb-2021Oryza barthii59.071e-180 523
LLPS-Via-0894Vigna angularis59.070.0 533
LLPS-Sot-0706Solanum tuberosum59.070.0 540
LLPS-Met-1954Medicago truncatula59.070.0 538
LLPS-Orm-1637Oryza meridionalis59.073e-180 521
LLPS-Hov-1986Hordeum vulgare58.882e-156 462
LLPS-Orni-1564Oryza nivara58.843e-179 519
LLPS-Orgl-1839Oryza glumaepatula58.841e-179 520
LLPS-Orp-1858Oryza punctata58.844e-179 519
LLPS-Orr-1536Oryza rufipogon58.843e-179 519
LLPS-Org-0904Oryza glaberrima58.81e-178 518
LLPS-Ori-2027Oryza indica58.66e-179 518
LLPS-Dac-0783Daucus carota58.62e-180 520
LLPS-Coo-1599Colletotrichum orbiculare58.411e-172 502
LLPS-Cii-1815Ciona intestinalis58.30.0 546
LLPS-Gag-1228Gaeumannomyces graminis58.281e-180 523
LLPS-Cis-1648Ciona savignyi58.240.0 545
LLPS-Ast-1289Aspergillus terreus58.243e-176 511
LLPS-Nef-0979Neosartorya fischeri58.143e-170 496
LLPS-Gaa-2689Gasterosteus aculeatus58.023e-163 473
LLPS-Asc-1333Aspergillus clavatus57.918e-176 510
LLPS-Asn-0426Aspergillus nidulans57.914e-178 516
LLPS-Beb-0679Beauveria bassiana57.915e-173 503
LLPS-Asfu-0244Aspergillus fumigatus57.915e-169 493
LLPS-Map-0457Magnaporthe poae57.758e-178 516
LLPS-Scs-1053Sclerotinia sclerotiorum57.713e-179 518
LLPS-Cogr-0845Colletotrichum graminicola57.717e-165 483
LLPS-Fuo-0532Fusarium oxysporum57.482e-170 497
LLPS-Fuv-1495Fusarium verticillioides57.212e-168 491
LLPS-Lem-0426Leptosphaeria maculans57.188e-177 513
LLPS-Trr-1376Trichoderma reesei57.141e-166 496
LLPS-Cog-1539Colletotrichum gloeosporioides57.117e-163 476
LLPS-Gas-1099Galdieria sulphuraria57.019e-174 507
LLPS-Brn-1078Brassica napus56.861e-176 513
LLPS-Bro-0552Brassica oleracea56.863e-176 513
LLPS-Osl-1311Ostreococcus lucimarinus56.771e-166 486
LLPS-Mao-0740Magnaporthe oryzae56.316e-165 483
LLPS-Abg-0404Absidia glauca56.314e-172 501
LLPS-Lep-0938Leersia perrieri55.811e-154 476
LLPS-Pyt-1440Pyrenophora teres55.761e-171 498
LLPS-Pytr-0815Pyrenophora triticirepentis55.764e-171 497
LLPS-Tru-2077Triticum urartu55.762e-159 467
LLPS-Zyt-1067Zymoseptoria tritici55.711e-171 500
LLPS-Ved-0202Verticillium dahliae55.714e-162 474
LLPS-Phn-1569Phaeosphaeria nodorum55.534e-168 489
LLPS-Drm-1202Drosophila melanogaster55.298e-167 487
LLPS-Trv-1555Trichoderma virens54.999e-171 496
LLPS-Dos-0848Dothistroma septosporum54.655e-170 496
LLPS-Yal-1118Yarrowia lipolytica54.46e-165 482
LLPS-Usm-1300Ustilago maydis54.211e-159 468
LLPS-Blg-1042Blumeria graminis54.193e-168 491
LLPS-Miv-1386Microbotryum violaceum54.042e-157 462
LLPS-Mel-0942Melampsora laricipopulina53.72e-155 458
LLPS-Cym-0741Cyanidioschyzon merolae53.591e-160 472
LLPS-Tum-0172Tuber melanosporum53.495e-165 480
LLPS-Fus-0249Fusarium solani53.471e-162 476
LLPS-Vir-1848Vigna radiata53.023e-152 448
LLPS-Scc-0566Schizosaccharomyces cryophilus52.831e-159 471
LLPS-Scj-0042Schizosaccharomyces japonicus52.82e-165 485
LLPS-Scp-1340Schizosaccharomyces pombe52.676e-157 463
LLPS-Spr-0997Sporisorium reilianum51.986e-149 441
LLPS-Crn-1177Cryptococcus neoformans51.051e-146 437
LLPS-Cae-1323Caenorhabditis elegans51.022e-148 439
LLPS-Put-0458Puccinia triticina50.621e-99 311
LLPS-Sac-1043Saccharomyces cerevisiae50.354e-152 449
LLPS-Pug-0053Puccinia graminis50.352e-143 427
LLPS-Asg-0704Ashbya gossypii49.658e-146 432
LLPS-Kop-1054Komagataella pastoris49.077e-161 471
LLPS-Chr-0669Chlamydomonas reinhardtii48.787e-143 431
LLPS-Asf-0427Aspergillus flavus46.821e-137 412
LLPS-Chc-1133Chondrus crispus44.72e-113 350
LLPS-Ors-1002Oryza sativa39.347e-85 277
LLPS-Orbr-1081Oryza brachyantha39.342e-85 278