• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orn-2917

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
Ensembl Gene: ENSONIG00000001587.1
Ensembl Protein: ENSONIP00000001987.1
Organism: Oreochromis niloticus
Taxa ID: 8128
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSONIT00000001986.1ENSONIP00000001987.1
UniProtI3IZE7, I3IZE7_ORENI
GeneBankAERX01046503

▼ SEQUENCE

Protein Sequence (FASTA)
1     GKPMRESLGE  ISYSASFLEW  FSEEARRVYG  DIVPSPAKDR  KLLLLKQPVG  VASIITPWNF  60
61    PSAMITRKVG  AALAAGCTVV  VKPAEDTPLS  ALALAELAEQ  AGIPAGVFNV  VPCSRESTPS  120
121   VGRVLCTDPL  VAKISFTGST  ATGKVLLKMA  ADTVKKVSME  LGGHAPFIVF  DSADLDKAVG  180
181   GAMASKFRNS  GQTCVCSNRF  LVQSAVYDRF  VEKLGGAMDA  ELRLGHGSEP  DTTQGPLINA  240
241   RAAEKVLHQI  SDAVSRGAKV  VKGGKRLDGS  FMEPTLLADV  TADMLCTKEE  TFGPLVPVIR  300
301   FNTEEEALAV  ANATSVGLAG  YFYSQDVRQI  WRVAEALELG  IVGVNEGLVS  TPEATFGGVK  360
361   ESGLGREGSK  YGIDEYLEVK  YVCFGGLKP  389
Nucleotide CDS Sequence (FASTA)
1     GGTAAACCGA  TGCGTGAGTC  TCTCGGGGAG  ATCTCGTACT  CCGCCTCCTT  CCTCGAGTGG  60
61    TTTTCTGAGG  AGGCGCGGCG  AGTTTACGGT  GACATCGTGC  CGTCTCCAGC  CAAAGACAGA  120
121   AAGCTCCTCC  TCCTGAAGCA  GCCGGTGGGC  GTGGCCTCCA  TCATCACACC  GTGGAACTTC  180
181   CCCAGCGCCA  TGATCACCAG  GAAGGTCGGC  GCCGCGCTGG  CCGCCGGCTG  CACGGTGGTG  240
241   GTTAAACCAG  CTGAGGACAC  GCCGCTATCG  GCTCTCGCAC  TGGCAGAGCT  GGCGGAGCAG  300
301   GCGGGGATCC  CGGCAGGGGT  GTTCAATGTG  GTTCCGTGCT  CCAGAGAGTC  GACGCCCTCG  360
361   GTCGGGCGGG  TCCTCTGCAC  CGACCCTCTG  GTGGCTAAAA  TCTCCTTCAC  TGGATCCACG  420
421   GCGACCGGGA  AGGTGTTGCT  GAAAATGGCC  GCTGACACTG  TGAAGAAGGT  ATCTATGGAA  480
481   CTGGGTGGCC  ACGCCCCCTT  CATTGTGTTT  GACAGCGCAG  ACCTTGACAA  AGCGGTGGGC  540
541   GGAGCCATGG  CATCCAAGTT  CAGGAACTCG  GGCCAGACGT  GCGTGTGCTC  GAACCGGTTT  600
601   CTGGTCCAGA  GTGCCGTCTA  CGATCGCTTC  GTGGAAAAGT  TGGGGGGAGC  GATGGATGCC  660
661   GAGCTGCGTC  TGGGTCACGG  CTCGGAGCCC  GACACCACGC  AGGGGCCGCT  CATCAACGCC  720
721   CGCGCCGCAG  AGAAGGTGCT  CCATCAGATT  TCGGACGCCG  TCTCCCGCGG  GGCGAAGGTG  780
781   GTGAAAGGTG  GGAAGCGCCT  CGACGGCTCA  TTCATGGAGC  CGACTCTGCT  GGCCGACGTC  840
841   ACCGCCGACA  TGCTGTGCAC  GAAGGAGGAA  ACCTTTGGGC  CGCTCGTGCC  CGTCATCAGG  900
901   TTTAACACGG  AGGAGGAGGC  TCTGGCTGTT  GCTAACGCGA  CCAGCGTCGG  GCTGGCAGGT  960
961   TACTTCTACT  CGCAGGACGT  GAGGCAGATC  TGGCGGGTGG  CGGAGGCGTT  GGAGTTGGGG  1020
1021  ATCGTCGGCG  TCAATGAGGG  GCTGGTGTCC  ACGCCAGAGG  CCACGTTTGG  CGGGGTGAAG  1080
1081  GAATCCGGCC  TGGGCCGTGA  GGGCTCCAAG  TACGGCATCG  ACGAGTACCT  GGAAGTGAAG  1140
1141  TACGTGTGCT  TTGGAGGCCT  CAAACCATGA  1170

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orl-3068Oryzias latipes88.690.0 698
LLPS-Xim-1113Xiphophorus maculatus87.150.0 657
LLPS-Pof-2496Poecilia formosa86.120.0 626
LLPS-Tar-1463Takifugu rubripes85.350.0 669
LLPS-Scf-0234Scleropages formosus83.980.0 664
LLPS-Icp-1851Ictalurus punctatus83.250.0 657
LLPS-Asm-1363Astyanax mexicanus83.20.0 656
LLPS-Ten-2485Tetraodon nigroviridis83.030.0 653
LLPS-Scm-1181Scophthalmus maximus82.411e-179 509
LLPS-Leo-1253Lepisosteus oculatus81.910.0 639
LLPS-Dar-2239Danio rerio81.650.0 654
LLPS-Lac-3805Latimeria chalumnae77.630.0 585
LLPS-Anp-2402Anas platyrhynchos76.610.0 587
LLPS-Anc-3722Anolis carolinensis75.90.0 597
LLPS-Tag-2835Taeniopygia guttata75.840.0 579
LLPS-Gaga-2600Gallus gallus75.580.0 582
LLPS-Sah-2527Sarcophilus harrisii75.580.0 595
LLPS-Meg-3046Meleagris gallopavo75.56e-160 461
LLPS-Fia-0111Ficedula albicollis75.380.0 575
LLPS-Pes-3683Pelodiscus sinensis75.060.0 593
LLPS-Bot-1124Bos taurus74.810.0 568
LLPS-Orc-3634Oryctolagus cuniculus74.550.0 586
LLPS-Ran-0495Rattus norvegicus74.550.0 578
LLPS-Mum-3573Mus musculus74.550.0 580
LLPS-Fud-4075Fukomys damarensis74.550.0 584
LLPS-Eqc-4781Equus caballus74.540.0 566
LLPS-Cap-3349Cavia porcellus74.290.0 584
LLPS-Xet-2846Xenopus tropicalis74.290.0 580
LLPS-Poa-4291Pongo abelii74.040.0 563
LLPS-Urm-3944Ursus maritimus74.040.0 584
LLPS-Myl-4237Myotis lucifugus74.040.0 580
LLPS-Caf-3955Canis familiaris73.970.0 582
LLPS-Mam-4109Macaca mulatta73.780.0 580
LLPS-Nol-3639Nomascus leucogenys73.780.0 560
LLPS-Ict-3355Ictidomys tridecemlineatus73.780.0 575
LLPS-Man-1468Macaca nemestrina73.780.0 580
LLPS-Dio-2936Dipodomys ordii73.780.0 581
LLPS-Mal-4524Mandrillus leucophaeus73.780.0 580
LLPS-Ova-4236Ovis aries73.780.0 587
LLPS-Maf-0189Macaca fascicularis73.780.0 580
LLPS-Chs-1378Chlorocebus sabaeus73.780.0 583
LLPS-Cea-3446Cercocebus atys73.780.0 581
LLPS-Loa-3559Loxodonta africana73.660.0 566
LLPS-Otg-4727Otolemur garnettii73.520.0 577
LLPS-Paa-1387Papio anubis73.520.0 577
LLPS-Caj-4578Callithrix jacchus73.520.0 555
LLPS-Mea-3745Mesocricetus auratus73.493e-167 484
LLPS-Fec-3193Felis catus73.260.0 574
LLPS-Sus-4136Sus scrofa73.260.0 558
LLPS-Aon-4135Aotus nancymaae73.260.0 554
LLPS-Rhb-4382Rhinopithecus bieti73.040.0 562
LLPS-Tut-1900Tursiops truncatus72.750.0 566
LLPS-Pat-4613Pan troglodytes71.640.0 552
LLPS-Pap-0197Pan paniscus71.640.0 553
LLPS-Hos-1667Homo sapiens71.390.0 552
LLPS-Gog-3741Gorilla gorilla71.390.0 553
LLPS-Cas-3494Carlito syrichta70.720.0 551
LLPS-Gaa-2689Gasterosteus aculeatus70.289e-180 513
LLPS-Mod-2720Monodelphis domestica65.552e-179 516
LLPS-Cii-1815Ciona intestinalis62.054e-171 494
LLPS-Art-2504Arabidopsis thaliana61.542e-158 463
LLPS-Cis-1648Ciona savignyi61.241e-169 491
LLPS-Arl-2000Arabidopsis lyrata61.035e-155 455
LLPS-Thc-2154Theobroma cacao61.031e-156 459
LLPS-Tra-2052Triticum aestivum60.676e-155 455
LLPS-Gor-2658Gossypium raimondii60.633e-152 448
LLPS-Brr-1196Brassica rapa60.512e-157 461
LLPS-Brn-1078Brassica napus60.511e-156 460
LLPS-Zem-1986Zea mays60.411e-154 454
LLPS-Met-1954Medicago truncatula60.264e-158 462
LLPS-Sob-1449Sorghum bicolor60.153e-155 455
LLPS-Sei-0219Setaria italica60.157e-156 457
LLPS-Hea-2366Helianthus annuus60.153e-153 452
LLPS-Coc-1896Corchorus capsularis60.058e-151 444
LLPS-Bro-0552Brassica oleracea60.02e-155 457
LLPS-Viv-2362Vitis vinifera59.92e-153 451
LLPS-Brd-1084Brachypodium distachyon59.98e-154 452
LLPS-Sem-0586Selaginella moellendorffii59.852e-157 460
LLPS-Cus-0703Cucumis sativus59.644e-154 453
LLPS-Pot-0905Populus trichocarpa59.494e-153 450
LLPS-Glm-0594Glycine max59.493e-157 461
LLPS-Abg-0404Absidia glauca59.434e-148 437
LLPS-Prp-1254Prunus persica59.387e-155 454
LLPS-Mua-1846Musa acuminata59.315e-129 382
LLPS-Phv-1203Phaseolus vulgaris59.36e-133 392
LLPS-Orm-1637Oryza meridionalis59.232e-154 454
LLPS-Orp-1858Oryza punctata59.234e-154 452
LLPS-Via-0894Vigna angularis59.231e-156 460
LLPS-Orb-2021Oryza barthii59.231e-154 454
LLPS-Ori-2027Oryza indica59.232e-153 451
LLPS-Hov-1986Hordeum vulgare59.215e-132 397
LLPS-Osl-1311Ostreococcus lucimarinus59.135e-150 441
LLPS-Nia-1040Nicotiana attenuata59.136e-154 452
LLPS-Orr-1536Oryza rufipogon58.973e-153 450
LLPS-Amt-0664Amborella trichopoda58.971e-154 453
LLPS-Orgl-1839Oryza glumaepatula58.976e-154 452
LLPS-Orni-1564Oryza nivara58.973e-153 450
LLPS-Org-0904Oryza glaberrima58.931e-152 449
LLPS-Sot-0706Solanum tuberosum58.871e-154 453
LLPS-Sol-1705Solanum lycopersicum58.871e-154 454
LLPS-Php-1916Physcomitrella patens58.612e-150 442
LLPS-Mae-2421Manihot esculenta58.211e-155 457
LLPS-Aso-1203Aspergillus oryzae57.971e-147 435
LLPS-Drm-1202Drosophila melanogaster57.83e-151 445
LLPS-Nef-0979Neosartorya fischeri57.298e-141 419
LLPS-Asc-1333Aspergillus clavatus57.291e-146 434
LLPS-Cog-1539Colletotrichum gloeosporioides57.221e-138 412
LLPS-Nec-0663Neurospora crassa57.187e-148 437
LLPS-Asni-0948Aspergillus niger56.933e-146 431
LLPS-Gag-1228Gaeumannomyces graminis56.744e-146 432
LLPS-Dac-0783Daucus carota56.561e-145 429
LLPS-Asfu-0244Aspergillus fumigatus56.525e-138 411
LLPS-Map-0457Magnaporthe poae56.494e-147 435
LLPS-Cogr-0845Colletotrichum graminicola56.415e-134 401
LLPS-Mao-0740Magnaporthe oryzae56.416e-137 409
LLPS-Ved-0202Verticillium dahliae56.193e-139 413
LLPS-Coo-1599Colletotrichum orbiculare56.152e-138 412
LLPS-Trr-1376Trichoderma reesei56.051e-133 409
LLPS-Ast-1289Aspergillus terreus56.012e-141 419
LLPS-Zyt-1067Zymoseptoria tritici55.647e-146 432
LLPS-Beb-0679Beauveria bassiana55.55e-137 409
LLPS-Tru-2077Triticum urartu55.416e-140 415
LLPS-Fuo-0532Fusarium oxysporum55.382e-137 410
LLPS-Fuv-1495Fusarium verticillioides55.381e-134 403
LLPS-Lem-0426Leptosphaeria maculans55.279e-143 424
LLPS-Gas-1099Galdieria sulphuraria55.245e-139 416
LLPS-Phn-1569Phaeosphaeria nodorum55.012e-138 411
LLPS-Lep-0938Leersia perrieri54.873e-127 401
LLPS-Asn-0426Aspergillus nidulans54.731e-141 421
LLPS-Miv-1386Microbotryum violaceum54.715e-135 402
LLPS-Usm-1300Ustilago maydis54.56e-141 418
LLPS-Scs-1053Sclerotinia sclerotiorum54.21e-141 420
LLPS-Pytr-0815Pyrenophora triticirepentis53.981e-137 409
LLPS-Pyt-1440Pyrenophora teres53.948e-139 412
LLPS-Yal-1118Yarrowia lipolytica53.833e-139 414
LLPS-Cym-0741Cyanidioschyzon merolae53.615e-131 394
LLPS-Fus-0249Fusarium solani53.552e-140 417
LLPS-Cae-1323Caenorhabditis elegans53.396e-131 392
LLPS-Vir-1848Vigna radiata53.332e-127 382
LLPS-Tum-0172Tuber melanosporum53.089e-139 410
LLPS-Scc-0566Schizosaccharomyces cryophilus53.03e-129 391
LLPS-Spr-0997Sporisorium reilianum52.962e-130 391
LLPS-Trv-1555Trichoderma virens52.939e-143 422
LLPS-Put-0458Puccinia triticina52.846e-88 279
LLPS-Dos-0848Dothistroma septosporum52.821e-136 408
LLPS-Scj-0042Schizosaccharomyces japonicus52.739e-133 399
LLPS-Mel-0942Melampsora laricipopulina52.673e-133 399
LLPS-Scp-1340Schizosaccharomyces pombe52.312e-125 380
LLPS-Pug-0053Puccinia graminis51.933e-130 391
LLPS-Kop-1054Komagataella pastoris51.792e-142 422
LLPS-Sac-1043Saccharomyces cerevisiae51.542e-126 381
LLPS-Blg-1042Blumeria graminis50.644e-133 399
LLPS-Chr-0669Chlamydomonas reinhardtii50.371e-121 374
LLPS-Asg-0704Ashbya gossypii50.06e-120 364
LLPS-Crn-1177Cryptococcus neoformans49.875e-126 382
LLPS-Asf-0427Aspergillus flavus47.922e-122 370
LLPS-Chc-1133Chondrus crispus44.82e-92 293
LLPS-Ors-1002Oryza sativa39.795e-73 244
LLPS-Orbr-1081Oryza brachyantha39.641e-72 243