• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ors-1836
Os01g0505400

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: 2-hydroxyacyl-CoA lyase; 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Oxalyl-CoA decarboxylase
Gene Name: Os01g0505400, LOC_Os01g32080
Ensembl Gene: Os01g0505400
Ensembl Protein: Os01t0505400-02
Organism: Oryza sativa
Taxa ID: 39947
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MATDTAAPAA  MKVDGSALAG  RALAAAGARH  MFGVVGIPVT  SLASRAAAAG  VRFLAFRNEQ  60
61    SAGYAAAAYG  FLTGSPGLLL  TVSGPGCVHG  LAGLSHATAN  AWPLLMVSGS  CSQPDAGRGD  120
121   FQELDQIAAT  KPFIKIAVKA  TTIADIPRLV  FQALAATVSG  RPGGCYLDIP  SDVLHQTLTE  180
181   SEAAALIDAA  AADSAKSDSS  PPKHKSLDEG  IEKAAELLRR  AERPLVVFGK  GAAYSRAEDA  240
241   IWKLVDTTGI  PFLPTPMGKG  VVPDTHPLSA  TAARSLAIGQ  CDVALVVGAR  LNWLLHFGEP  300
301   PKWSKDVKFI  LVDVCEEEIE  LRKPHVGIVG  DAKRVVELIN  REIKDQPFCL  APSHPWVEAI  360
361   TKKARDNVLK  MEAQLAKDVV  PFNFLTPLRI  IRDAILAEGN  PAPVVVSEGA  NTMDVGRAVL  420
421   VQNEPRTRLD  AGTWGTMGVG  LGFCVAAAVA  EPDRLVVAVE  GDSGFGFSAM  EVEV  474
Nucleotide CDS Sequence (FASTA)
1     ATGGCGACCG  ACACCGCCGC  TCCAGCTGCC  ATGAAGGTCG  ACGGCAGCGC  CCTCGCCGGG  60
61    CGCGCGCTGG  CCGCGGCCGG  GGCGCGGCAC  ATGTTCGGGG  TGGTGGGCAT  CCCGGTCACC  120
121   TCCCTCGCGT  CCCGCGCCGC  GGCCGCCGGT  GTCCGCTTCC  TCGCCTTCCG  CAACGAGCAG  180
181   TCCGCGGGCT  ACGCCGCCGC  CGCCTACGGC  TTCCTCACCG  GCTCCCCCGG  CCTGCTCCTC  240
241   ACCGTCTCCG  GCCCCGGCTG  CGTCCACGGC  CTCGCGGGCC  TCTCCCACGC  CACCGCCAAC  300
301   GCCTGGCCGC  TCCTCATGGT  CTCCGGCTCC  TGCTCCCAGC  CAGACGCCGG  CAGGGGCGAC  360
361   TTCCAGGAGC  TCGACCAGAT  CGCCGCCACC  AAGCCTTTCA  TCAAGATCGC  CGTCAAGGCA  420
421   ACCACCATCG  CCGACATCCC  TCGCCTCGTC  TTCCAGGCCC  TCGCCGCCAC  CGTCTCCGGC  480
481   CGCCCCGGCG  GCTGCTACCT  CGACATCCCA  TCCGACGTCC  TCCACCAAAC  CCTCACGGAA  540
541   TCGGAGGCCG  CCGCCCTCAT  CGACGCTGCC  GCCGCCGATT  CGGCCAAATC  CGATTCTTCT  600
601   CCACCCAAGC  ACAAGTCCCT  GGACGAGGGA  ATCGAGAAGG  CGGCGGAGCT  GCTCCGCCGC  660
661   GCGGAGCGGC  CTCTGGTTGT  GTTTGGGAAG  GGCGCGGCGT  ATTCTCGCGC  TGAGGACGCC  720
721   ATCTGGAAGC  TGGTGGATAC  CACGGGCATC  CCCTTCCTCC  CGACGCCGAT  GGGAAAGGGT  780
781   GTTGTGCCCG  ACACGCACCC  ACTGTCGGCC  ACCGCGGCGC  GCTCTCTCGC  CATTGGGCAA  840
841   TGTGATGTGG  CATTAGTCGT  TGGTGCTCGG  CTTAATTGGT  TGCTTCACTT  CGGTGAGCCA  900
901   CCCAAATGGT  CCAAAGATGT  GAAATTCATA  CTTGTGGATG  TCTGCGAGGA  GGAGATTGAG  960
961   CTCCGGAAGC  CGCATGTTGG  AATTGTTGGG  GATGCCAAGA  GAGTTGTGGA  GCTTATCAAT  1020
1021  AGGGAGATCA  AGGACCAGCC  ATTCTGCTTG  GCACCATCAC  ACCCATGGGT  TGAAGCAATC  1080
1081  ACCAAGAAGG  CCAGGGACAA  TGTTCTTAAG  ATGGAGGCTC  AGCTTGCCAA  GGATGTTGTG  1140
1141  CCATTCAATT  TCCTGACACC  TTTGCGGATT  ATCCGGGATG  CTATACTTGC  TGAGGGAAAC  1200
1201  CCTGCTCCTG  TAGTGGTCTC  AGAAGGGGCA  AACACCATGG  ATGTCGGCAG  GGCAGTGCTT  1260
1261  GTGCAGAACG  AGCCGAGGAC  TAGACTGGAT  GCAGGTACAT  GGGGGACAAT  GGGAGTTGGA  1320
1321  TTGGGATTCT  GTGTTGCAGC  TGCAGTTGCT  GAGCCTGATC  GACTTGTGGT  TGCTGTGGAG  1380
1381  GGTGATTCTG  GATTTGGATT  CAGTGCAATG  GAGGTTGAGG  TATGA  1425

▼ KEYWORD

ID
Family
Complete proteome
Decarboxylase
Lyase
Magnesium
Metal-binding
Reference proteome
Thiamine pyrophosphate

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Peroxisome
Molecular Function
Carbon-carbon lyase activity
Molecular Function
Carboxy-lyase activity
Molecular Function
Magnesium ion binding
Molecular Function
Thiamine pyrophosphate binding
Biological Process
Fatty acid alpha-oxidation

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orr-1412Oryza rufipogon100.00.0 858
LLPS-Org-0043Oryza glaberrima99.580.0 853
LLPS-Ori-1818Oryza indica99.580.0 853
LLPS-Orni-1595Oryza nivara99.580.0 853
LLPS-Orgl-2238Oryza glumaepatula99.150.0 848
LLPS-Orm-0828Oryza meridionalis98.940.0 849
LLPS-Orp-0455Oryza punctata97.190.0 815
LLPS-Orbr-2315Oryza brachyantha94.290.0 673
LLPS-Orb-1323Oryza barthii92.810.0 792
LLPS-Lep-0929Leersia perrieri92.420.0 808
LLPS-Sei-2284Setaria italica91.850.0 658
LLPS-Tru-1379Triticum urartu91.282e-140 414
LLPS-Sob-2090Sorghum bicolor91.140.0 785
LLPS-Zem-0673Zea mays90.510.0 784
LLPS-Tra-0565Triticum aestivum89.010.0 777
LLPS-Hov-1288Hordeum vulgare88.790.0 771
LLPS-Brd-1289Brachypodium distachyon88.790.0 771
LLPS-Prp-1797Prunus persica75.110.0 685
LLPS-Mae-1039Manihot esculenta75.00.0 690
LLPS-Viv-1697Vitis vinifera74.240.0 687
LLPS-Pot-2266Populus trichocarpa73.750.0 668
LLPS-Coc-1551Corchorus capsularis73.710.0 646
LLPS-Dac-0528Daucus carota73.480.0 672
LLPS-Thc-1945Theobroma cacao73.280.0 663
LLPS-Vir-1551Vigna radiata73.220.0 679
LLPS-Phv-1420Phaseolus vulgaris73.00.0 683
LLPS-Via-1188Vigna angularis73.00.0 681
LLPS-Brr-0930Brassica rapa72.940.0 676
LLPS-Nia-2210Nicotiana attenuata72.730.0 676
LLPS-Brn-3231Brassica napus72.730.0 672
LLPS-Gor-2500Gossypium raimondii72.670.0 653
LLPS-Bro-1680Brassica oleracea72.520.0 667
LLPS-Glm-0904Glycine max72.410.0 677
LLPS-Art-0853Arabidopsis thaliana72.190.0 670
LLPS-Arl-2569Arabidopsis lyrata72.130.0 673
LLPS-Cus-1828Cucumis sativus71.80.0 652
LLPS-Sol-0725Solanum lycopersicum71.460.0 673
LLPS-Hea-1622Helianthus annuus71.370.0 667
LLPS-Sot-0150Solanum tuberosum70.610.0 650
LLPS-Met-2586Medicago truncatula70.110.0 641
LLPS-Amt-0176Amborella trichopoda66.880.0 605
LLPS-Php-0305Physcomitrella patens65.730.0 606
LLPS-Sem-1884Selaginella moellendorffii62.980.0 553
LLPS-Mua-2273Musa acuminata61.724e-174 505
LLPS-Ict-3882Ictidomys tridecemlineatus48.356e-1993.6
LLPS-Leo-2029Lepisosteus oculatus45.422e-84 269
LLPS-Asn-0626Aspergillus nidulans44.472e-118 367
LLPS-Nef-0182Neosartorya fischeri44.284e-115 358
LLPS-Asfu-1558Aspergillus fumigatus44.092e-114 358
LLPS-Gas-0520Galdieria sulphuraria44.097e-131 412
LLPS-Asf-1176Aspergillus flavus44.062e-117 364
LLPS-Asni-0783Aspergillus niger43.99e-116 360
LLPS-Ast-1530Aspergillus terreus43.231e-112 352
LLPS-Aso-1509Aspergillus oryzae43.22e-111 348
LLPS-Abg-1282Absidia glauca43.182e-49 177
LLPS-Asc-0597Aspergillus clavatus42.861e-114 357
LLPS-Yal-1553Yarrowia lipolytica42.77e-115 356
LLPS-Dos-0860Dothistroma septosporum42.173e-110 345
LLPS-Pof-2691Poecilia formosa42.046e-112 350
LLPS-Scc-1418Schizosaccharomyces cryophilus41.51e-103 328
LLPS-Blg-0044Blumeria graminis41.217e-108 339
LLPS-Scj-1248Schizosaccharomyces japonicus40.82e-102 324
LLPS-Zyt-1148Zymoseptoria tritici40.267e-94 303
LLPS-Otg-3475Otolemur garnettii39.832e-106 334
LLPS-Lac-3565Latimeria chalumnae39.65e-102 323
LLPS-Tum-1484Tuber melanosporum39.316e-98 313
LLPS-Scp-0869Schizosaccharomyces pombe39.113e-89 290
LLPS-Sac-1639Saccharomyces cerevisiae38.532e-86 283
LLPS-Mea-1927Mesocricetus auratus38.073e-25 109
LLPS-Asg-1158Ashbya gossypii36.983e-82 271
LLPS-Cea-4654Cercocebus atys29.662e-1273.2
LLPS-Paa-2099Papio anubis29.662e-1273.2
LLPS-Rhb-2423Rhinopithecus bieti29.323e-0963.5
LLPS-Cym-0060Cyanidioschyzon merolae27.748e-32 132
LLPS-Dio-2110Dipodomys ordii27.192e-28 122
LLPS-Ved-1214Verticillium dahliae27.021e-2099.0
LLPS-Miv-0294Microbotryum violaceum26.981e-27 120
LLPS-Urm-1547Ursus maritimus26.793e-37 148
LLPS-Caf-1669Canis familiaris26.794e-37 147
LLPS-Phn-1021Phaeosphaeria nodorum26.646e-21 100
LLPS-Coo-0889Colletotrichum orbiculare26.642e-2098.2
LLPS-Caj-3926Callithrix jacchus26.379e-33 135
LLPS-Hos-3202Homo sapiens26.223e-36 145
LLPS-Aim-2020Ailuropoda melanoleuca26.215e-36 144
LLPS-Chr-0999Chlamydomonas reinhardtii26.22e-27 120
LLPS-Mup-1873Mustela putorius furo26.161e-35 143
LLPS-Fec-4383Felis catus26.116e-36 144
LLPS-Osl-0617Ostreococcus lucimarinus26.089e-29 123
LLPS-Pat-2611Pan troglodytes26.01e-35 143
LLPS-Pap-4662Pan paniscus26.01e-35 143
LLPS-Aon-2359Aotus nancymaae26.06e-36 144
LLPS-Chs-2811Chlorocebus sabaeus26.01e-33 137
LLPS-Gog-2422Gorilla gorilla26.02e-35 143
LLPS-Mal-1599Mandrillus leucophaeus26.05e-36 144
LLPS-Ran-3752Rattus norvegicus25.951e-32 135
LLPS-Cogr-0210Colletotrichum graminicola25.916e-1994.0
LLPS-Fuv-1565Fusarium verticillioides25.914e-21 100
LLPS-Kop-0831Komagataella pastoris25.852e-2098.2
LLPS-Xim-3758Xiphophorus maculatus25.842e-32 134
LLPS-Chc-0693Chondrus crispus25.833e-33 136
LLPS-Man-3069Macaca nemestrina25.795e-35 142
LLPS-Mam-4323Macaca mulatta25.794e-35 142
LLPS-Poa-3900Pongo abelii25.792e-35 142
LLPS-Maf-4582Macaca fascicularis25.795e-35 142
LLPS-Dar-3270Danio rerio25.741e-33 137
LLPS-Sus-1689Sus scrofa25.742e-34 140
LLPS-Pug-0711Puccinia graminis25.63e-28 122
LLPS-Loa-4014Loxodonta africana25.583e-33 136
LLPS-Cas-2594Carlito syrichta25.587e-34 138
LLPS-Myl-4494Myotis lucifugus25.582e-34 140
LLPS-Pytr-1156Pyrenophora triticirepentis25.572e-31 131
LLPS-Cog-0894Colletotrichum gloeosporioides25.561e-2099.4
LLPS-Mum-3955Mus musculus25.533e-31 130
LLPS-Bot-1933Bos taurus25.533e-34 139
LLPS-Xet-0913Xenopus tropicalis25.491e-28 122
LLPS-Ten-2268Tetraodon nigroviridis25.422e-32 134
LLPS-Mel-1230Melampsora laricipopulina25.31e-29 126
LLPS-Sah-3008Sarcophilus harrisii25.262e-29 125
LLPS-Put-0112Puccinia triticina25.26e-27 118
LLPS-Nol-3738Nomascus leucogenys25.196e-1994.0
LLPS-Cap-3517Cavia porcellus25.119e-30 126
LLPS-Orn-4079Oreochromis niloticus25.056e-33 135
LLPS-Icp-2586Ictalurus punctatus25.057e-30 127
LLPS-Gag-0030Gaeumannomyces graminis25.03e-1995.1
LLPS-Map-0593Magnaporthe poae25.05e-25 112
LLPS-Tar-3932Takifugu rubripes24.954e-30 127
LLPS-Cae-1360Caenorhabditis elegans24.98e-29 123
LLPS-Fud-1240Fukomys damarensis24.893e-31 130
LLPS-Ova-2860Ovis aries24.896e-33 135
LLPS-Scm-3482Scophthalmus maximus24.845e-34 139
LLPS-Anc-2796Anolis carolinensis24.631e-34 140
LLPS-Gaga-1663Gallus gallus24.635e-26 115
LLPS-Crn-0225Cryptococcus neoformans24.551e-25 114
LLPS-Mod-3743Monodelphis domestica24.531e-27 120
LLPS-Gaa-3363Gasterosteus aculeatus24.539e-33 135
LLPS-Beb-0120Beauveria bassiana24.417e-26 115
LLPS-Lem-1241Leptosphaeria maculans24.381e-23 107
LLPS-Nec-0120Neurospora crassa24.376e-29 124
LLPS-Pyt-0190Pyrenophora teres24.321e-30 129
LLPS-Spr-0712Sporisorium reilianum24.212e-26 117
LLPS-Usm-1217Ustilago maydis24.211e-25 114
LLPS-Eqc-4672Equus caballus24.132e-24 110
LLPS-Cis-1687Ciona savignyi24.092e-28 122
LLPS-Trr-1032Trichoderma reesei23.966e-0962.4
LLPS-Trv-0270Trichoderma virens23.93e-27 119
LLPS-Fus-0513Fusarium solani23.874e-26 115
LLPS-Scf-3668Scleropages formosus23.744e-30 127
LLPS-Mao-0465Magnaporthe oryzae23.391e-25 114
LLPS-Orl-0481Oryzias latipes23.161e-27 120
LLPS-Pes-1636Pelodiscus sinensis22.953e-29 125
LLPS-Fuo-0524Fusarium oxysporum22.152e-21 101