• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orl-1517
rpl8

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: 60S ribosomal protein L8
Gene Name: rpl8
Ensembl Gene: ENSORLG00000010680.2
Ensembl Protein: ENSORLP00000013387.1
Organism: Oryzias latipes
Taxa ID: 8090
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGRVIRGQRK  GAGSVFKAHV  KHRKGAAKLR  HIDFAERNGY  IKGIVKDIIH  DPGRGAPLAK  60
61    VVFRDPYRFK  KRTELFIAAE  GIHTGQFIYC  GKKAQLNIGN  VLPVGTMPEG  TIICCLEEKP  120
121   GDRGKLARAS  GNYATVISHN  PETKKSRVKL  PSGAKKVIAS  ANRAVVGVVA  GGGRIDKPIL  180
181   KAGRAYHKYK  AKRNCWPRVR  GVAMNPVEHP  FGGGNHQHIG  KPSTIRRDAP  AGRKVGLIAA  240
241   RRTGRLRGTK  TVQEKEN  257
Nucleotide CDS Sequence (FASTA)
1     ATGGGACGTG  TGATCAGGGG  ACAGAGAAAA  GGTGCGGGCT  CCGTGTTCAA  AGCCCACGTC  60
61    AAGCACAGGA  AAGGTGCTGC  TAAACTCCGC  CACATTGACT  TCGCTGAACG  TAATGGTTAC  120
121   ATCAAGGGGA  TTGTGAAGGA  CATCATCCAT  GACCCTGGCC  GTGGCGCTCC  CCTGGCCAAA  180
181   GTGGTTTTCC  GTGACCCGTA  CAGGTTTAAG  AAGAGGACGG  AGCTCTTCAT  CGCTGCTGAG  240
241   GGGATCCACA  CCGGGCAGTT  CATTTACTGC  GGCAAGAAGG  CTCAGCTGAA  CATCGGCAAT  300
301   GTTCTGCCCG  TGGGCACAAT  GCCCGAGGGA  ACCATCATCT  GCTGTCTGGA  GGAGAAGCCC  360
361   GGCGATCGAG  GCAAGCTAGC  CCGAGCCTCA  GGGAACTACG  CCACAGTCAT  CTCCCACAAC  420
421   CCCGAGACAA  AGAAATCAAG  AGTTAAGCTG  CCCTCAGGCG  CTAAGAAGGT  CATCGCCTCT  480
481   GCCAACAGAG  CCGTTGTCGG  TGTGGTTGCT  GGTGGAGGCC  GTATTGACAA  GCCCATCCTG  540
541   AAGGCTGGCC  GTGCCTATCA  CAAGTACAAG  GCCAAGAGGA  ACTGCTGGCC  ACGCGTCCGT  600
601   GGTGTGGCTA  TGAATCCTGT  TGAGCATCCA  TTCGGTGGTG  GTAACCATCA  GCACATCGGC  660
661   AAACCCTCCA  CCATCAGGAG  GGATGCACCT  GCTGGTCGCA  AGGTCGGTCT  CATTGCTGCC  720
721   CGCCGCACAG  GCAGACTGCG  TGGAACAAAG  ACCGTCCAGG  AGAAGGAGAA  CTAA  774

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orn-1098Oreochromis niloticus99.229e-176 492
LLPS-Scm-0641Scophthalmus maximus98.445e-175 490
LLPS-Gaa-0559Gasterosteus aculeatus98.441e-174 489
LLPS-Pof-0743Poecilia formosa97.671e-173 486
LLPS-Dar-2186Danio rerio97.672e-174 488
LLPS-Scf-0558Scleropages formosus97.672e-174 489
LLPS-Xim-1530Xiphophorus maculatus97.671e-173 486
LLPS-Mal-1488Mandrillus leucophaeus97.631e-141 404
LLPS-Urm-0175Ursus maritimus97.466e-130 375
LLPS-Ten-2378Tetraodon nigroviridis97.282e-172 483
LLPS-Icp-2935Ictalurus punctatus96.891e-172 484
LLPS-Leo-0337Lepisosteus oculatus96.55e-173 485
LLPS-Mam-2351Macaca mulatta96.113e-172 483
LLPS-Cap-0281Cavia porcellus96.113e-172 483
LLPS-Poa-0387Pongo abelii96.113e-172 483
LLPS-Caf-0926Canis familiaris96.113e-172 483
LLPS-Ict-1029Ictidomys tridecemlineatus96.113e-172 483
LLPS-Anc-1036Anolis carolinensis96.116e-173 484
LLPS-Nol-2721Nomascus leucogenys96.113e-172 483
LLPS-Cas-0012Carlito syrichta96.113e-172 483
LLPS-Man-0587Macaca nemestrina96.113e-172 483
LLPS-Fec-2446Felis catus96.113e-172 483
LLPS-Pat-1950Pan troglodytes96.113e-172 483
LLPS-Pap-0396Pan paniscus96.113e-172 483
LLPS-Hos-0259Homo sapiens96.113e-172 483
LLPS-Rhb-0883Rhinopithecus bieti96.113e-172 483
LLPS-Orc-0105Oryctolagus cuniculus96.113e-172 483
LLPS-Otg-0453Otolemur garnettii96.113e-172 483
LLPS-Bot-0034Bos taurus96.113e-172 483
LLPS-Dio-0210Dipodomys ordii96.113e-172 483
LLPS-Tut-0353Tursiops truncatus96.113e-172 483
LLPS-Aim-0092Ailuropoda melanoleuca96.113e-172 483
LLPS-Mup-1527Mustela putorius furo96.113e-172 483
LLPS-Myl-1364Myotis lucifugus96.113e-172 483
LLPS-Ova-1019Ovis aries96.113e-172 483
LLPS-Paa-0355Papio anubis96.113e-172 483
LLPS-Ran-2757Rattus norvegicus96.113e-172 483
LLPS-Aon-2435Aotus nancymaae96.113e-172 483
LLPS-Sah-0542Sarcophilus harrisii96.113e-172 483
LLPS-Cea-0161Cercocebus atys96.113e-172 483
LLPS-Sus-3192Sus scrofa96.113e-172 483
LLPS-Chs-1131Chlorocebus sabaeus96.113e-172 483
LLPS-Maf-2553Macaca fascicularis96.113e-172 483
LLPS-Mum-0364Mus musculus96.113e-172 483
LLPS-Caj-0961Callithrix jacchus96.113e-172 483
LLPS-Fud-0583Fukomys damarensis96.113e-172 483
LLPS-Gog-1292Gorilla gorilla96.113e-172 483
LLPS-Eqc-0755Equus caballus95.722e-171 481
LLPS-Lac-0899Latimeria chalumnae95.723e-172 483
LLPS-Mod-1466Monodelphis domestica95.724e-172 483
LLPS-Pes-0316Pelodiscus sinensis95.722e-171 481
LLPS-Xet-1703Xenopus tropicalis95.338e-172 482
LLPS-Loa-0805Loxodonta africana95.122e-132 380
LLPS-Tag-0832Taeniopygia guttata94.945e-171 480
LLPS-Gaga-2348Gallus gallus94.946e-171 479
LLPS-Meg-1323Meleagris gallopavo94.946e-171 479
LLPS-Fia-0655Ficedula albicollis94.946e-171 479
LLPS-Tar-0306Takifugu rubripes94.561e-152 434
LLPS-Asm-0072Astyanax mexicanus94.551e-169 476
LLPS-Anp-2489Anas platyrhynchos92.834e-160 452
LLPS-Drm-0687Drosophila melanogaster81.62e-139 399
LLPS-Cii-0097Ciona intestinalis78.122e-141 405
LLPS-Cis-0536Ciona savignyi77.347e-140 400
LLPS-Cae-0113Caenorhabditis elegans75.12e-132 382
LLPS-Abg-0563Absidia glauca74.021e-128 372
LLPS-Via-0366Vigna angularis73.393e-128 371
LLPS-Vir-0621Vigna radiata73.398e-128 370
LLPS-Gas-0970Galdieria sulphuraria73.281e-125 365
LLPS-Prp-0804Prunus persica72.587e-127 368
LLPS-Viv-0019Vitis vinifera72.581e-125 365
LLPS-Phv-0579Phaseolus vulgaris72.588e-127 368
LLPS-Glm-2560Glycine max72.585e-126 366
LLPS-Chr-0146Chlamydomonas reinhardtii72.333e-124 362
LLPS-Put-0497Puccinia triticina72.293e-125 363
LLPS-Pug-0287Puccinia graminis72.293e-125 363
LLPS-Coc-0534Corchorus capsularis72.184e-125 363
LLPS-Bro-0742Brassica oleracea72.185e-126 365
LLPS-Art-1472Arabidopsis thaliana72.188e-126 365
LLPS-Sei-1111Setaria italica72.187e-126 365
LLPS-Brn-0216Brassica napus72.185e-126 365
LLPS-Dac-0565Daucus carota72.187e-126 365
LLPS-Osl-0171Ostreococcus lucimarinus72.02e-118 346
LLPS-Orr-0867Oryza rufipogon71.775e-126 366
LLPS-Orm-0320Oryza meridionalis71.775e-126 366
LLPS-Org-0747Oryza glaberrima71.775e-126 366
LLPS-Orp-1596Oryza punctata71.775e-126 366
LLPS-Ors-0371Oryza sativa71.775e-126 366
LLPS-Lep-1163Leersia perrieri71.775e-126 366
LLPS-Orgl-0993Oryza glumaepatula71.775e-126 366
LLPS-Arl-0261Arabidopsis lyrata71.771e-125 365
LLPS-Cus-0219Cucumis sativus71.778e-125 362
LLPS-Met-1062Medicago truncatula71.777e-125 363
LLPS-Ori-0484Oryza indica71.775e-126 366
LLPS-Orb-1064Oryza barthii71.775e-126 366
LLPS-Orni-1105Oryza nivara71.775e-126 366
LLPS-Chc-0873Chondrus crispus71.658e-125 362
LLPS-Mua-0175Musa acuminata71.524e-67 212
LLPS-Gor-1353Gossypium raimondii71.378e-126 365
LLPS-Brr-1239Brassica rapa71.375e-125 363
LLPS-Sob-0774Sorghum bicolor71.376e-125 363
LLPS-Brd-1058Brachypodium distachyon71.372e-125 364
LLPS-Sem-0431Selaginella moellendorffii71.374e-123 358
LLPS-Sac-1102Saccharomyces cerevisiae71.265e-128 370
LLPS-Yal-0127Yarrowia lipolytica71.265e-127 368
LLPS-Mel-0812Melampsora laricipopulina71.262e-127 369
LLPS-Usm-0450Ustilago maydis71.086e-123 357
LLPS-Zem-1003Zea mays70.975e-124 360
LLPS-Nia-1583Nicotiana attenuata70.972e-123 359
LLPS-Mae-0013Manihot esculenta70.971e-123 360
LLPS-Orbr-0426Oryza brachyantha70.972e-124 362
LLPS-Tra-0741Triticum aestivum70.975e-124 360
LLPS-Hov-0005Hordeum vulgare70.976e-124 361
LLPS-Thc-0779Theobroma cacao70.979e-125 362
LLPS-Kop-0437Komagataella pastoris70.871e-121 354
LLPS-Spr-0509Sporisorium reilianum70.686e-122 355
LLPS-Sot-0754Solanum tuberosum70.568e-124 360
LLPS-Sol-1595Solanum lycopersicum70.568e-124 360
LLPS-Pot-1889Populus trichocarpa70.164e-124 361
LLPS-Amt-0630Amborella trichopoda70.164e-123 358
LLPS-Hea-0516Helianthus annuus70.161e-123 359
LLPS-Crn-0732Cryptococcus neoformans70.08e-119 347
LLPS-Php-0527Physcomitrella patens69.352e-120 351
LLPS-Asg-0122Ashbya gossypii69.294e-126 365
LLPS-Miv-0499Microbotryum violaceum68.99e-121 352
LLPS-Scs-0287Sclerotinia sclerotiorum68.92e-119 348
LLPS-Tru-0004Triticum urartu68.487e-121 353
LLPS-Mao-0369Magnaporthe oryzae68.119e-119 347
LLPS-Scj-0525Schizosaccharomyces japonicus67.723e-117 343
LLPS-Dos-0665Dothistroma septosporum67.321e-115 339
LLPS-Ved-0552Verticillium dahliae67.323e-118 346
LLPS-Cog-0825Colletotrichum gloeosporioides67.321e-118 347
LLPS-Scp-0362Schizosaccharomyces pombe67.324e-118 345
LLPS-Zyt-0653Zymoseptoria tritici67.323e-116 340
LLPS-Gag-0164Gaeumannomyces graminis67.325e-118 345
LLPS-Coo-0002Colletotrichum orbiculare67.321e-117 344
LLPS-Asc-0833Aspergillus clavatus66.931e-115 339
LLPS-Cym-0214Cyanidioschyzon merolae66.932e-112 331
LLPS-Cogr-0116Colletotrichum graminicola66.674e-115 338
LLPS-Trv-1009Trichoderma virens66.542e-114 336
LLPS-Asfu-0273Aspergillus fumigatus66.543e-115 338
LLPS-Ast-0628Aspergillus terreus66.544e-115 338
LLPS-Nef-0249Neosartorya fischeri66.544e-115 338
LLPS-Trr-0447Trichoderma reesei66.542e-114 336
LLPS-Blg-0664Blumeria graminis66.542e-114 336
LLPS-Fuo-0433Fusarium oxysporum66.148e-116 340
LLPS-Beb-0503Beauveria bassiana66.142e-114 336
LLPS-Fus-0012Fusarium solani66.146e-116 340
LLPS-Asf-0186Aspergillus flavus66.145e-114 335
LLPS-Nec-0088Neurospora crassa66.144e-116 340
LLPS-Scc-0681Schizosaccharomyces cryophilus66.142e-116 341
LLPS-Fuv-0530Fusarium verticillioides66.148e-116 340
LLPS-Map-0546Magnaporthe poae66.145e-117 342
LLPS-Asn-0320Aspergillus nidulans66.143e-112 330
LLPS-Pytr-0468Pyrenophora triticirepentis65.751e-113 335
LLPS-Pyt-0175Pyrenophora teres65.752e-113 333
LLPS-Asni-0037Aspergillus niger65.751e-113 334
LLPS-Lem-0703Leptosphaeria maculans65.357e-113 332
LLPS-Tum-0459Tuber melanosporum64.033e-105 314
LLPS-Phn-0669Phaeosphaeria nodorum59.841e-94 285