• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orc-1186
NEFL

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: NEFL
Ensembl Gene: ENSOCUG00000023836.2
Ensembl Protein: ENSOCUP00000017130.1
Organism: Oryctolagus cuniculus
Taxa ID: 9986
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
PML nuclear body, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSOCUT00000027500.2ENSOCUP00000017130.1
UniProtG1TJK2, G1TJK2_RABIT
GeneBankAAGW02011107

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSFSYEPYY  STSYKRRYVE  TPRVHISSVR  SGYSTARSAY  SSYSAPVSSS  LSVRRSYSSS  60
61    SGSLMPSLEN  LDLSQVAAIS  NDLKSIRTQE  KAQLQDLNDR  FASFIERVHE  LEQQNKVLEA  120
121   ELLVLRQKHS  EPSRFRALYE  QEIRDLRLAA  EDATNEKQAL  QGEREGLEET  LRNLQARYEE  180
181   EVLSREDAEG  RLMEARKGAD  EAALARAELE  KRIDSLMDEI  ALSEESARRG  DRRAAGADPV  240
241   RSDLRGDGRV  LQPDLSAALK  DIRAQYEKLG  RQETCRNAEE  WVQEPLHRAD  RERRPRTTDA  300
301   VRAAKDEVSE  SPPPCSRPKT  LKIEACRGMN  EALEKQLQEL  EDKQNADISA  MQDTINKLEN  360
361   ELRTTKSEMA  RYLKEYQDLL  NVKMALDIEI  AAYRKLLEGE  ETRLSFTSVG  SITSGYSQSS  420
421   QVFGRSAYGG  LQTSSYLMSA  RSFPTYYTSH  VQEEQIEVEE  TIEAAKAEEA  KDEPPSEGEA  480
481   EEEEEKKEEG  EEEEGAEEEE  AAKEESEEVK  EEEEEGGEGE  EGEETKEAEE  DEKKDEGAGE  540
541   EQATKKKD  548
Nucleotide CDS Sequence (FASTA)
1     ATGAGTTCGT  TCAGCTACGA  GCCGTACTAC  TCGACCTCCT  ACAAGCGGCG  CTACGTGGAG  60
61    ACGCCCCGGG  TGCACATCTC  CAGCGTGCGC  AGCGGCTACA  GCACCGCGCG  CTCCGCTTAC  120
121   TCCAGCTACT  CGGCACCGGT  CTCCTCCTCG  CTGTCCGTGC  GCCGCAGCTA  CTCCTCCAGC  180
181   TCCGGCTCCT  TGATGCCCAG  CCTGGAAAAC  CTCGACCTGA  GCCAGGTAGC  CGCCATCAGC  240
241   AACGACCTCA  AGTCGATCCG  CACGCAGGAG  AAGGCGCAGC  TGCAGGACCT  GAACGACCGC  300
301   TTCGCTAGCT  TCATCGAGCG  CGTGCACGAG  CTGGAGCAGC  AGAACAAGGT  CCTGGAAGCC  360
361   GAGCTGCTGG  TGCTGCGCCA  GAAGCACTCG  GAGCCGTCCC  GCTTCCGGGC  GCTGTACGAG  420
421   CAGGAGATCC  GCGACCTGCG  CCTGGCTGCC  GAAGACGCCA  CCAACGAGAA  GCAGGCGCTC  480
481   CAGGGCGAGC  GCGAAGGGCT  GGAGGAGACC  CTTCGCAACC  TGCAGGCGCG  CTATGAGGAA  540
541   GAGGTGCTGA  GCCGAGAGGA  CGCCGAGGGC  CGGCTGATGG  AGGCGCGCAA  AGGCGCTGAC  600
601   GAGGCGGCAC  TCGCTCGCGC  TGAGCTGGAG  AAGCGCATCG  ACAGCCTGAT  GGACGAAATC  660
661   GCCCTTTCTG  AAGAAAGTGC  ACGAAGAGGA  GATCGCCGAG  CTGCAGGCGC  AGATCCAGTA  720
721   CGCTCAGATC  TCCGTGGAGA  TGGACGTGTC  CTCCAGCCCG  ACCTCTCCGC  CGCCCTCAAG  780
781   GACATCCGTG  CACAGTACGA  GAAGCTGGGC  CGCCAAGAAA  CATGCAGAAA  CGCCGAAGAG  840
841   TGGGTTCAGG  AGCCGCTTCA  CCGTGCTGAC  CGAGAGCGCC  GGCCAAGAAC  AACCGACGCC  900
901   GTGCGCGCAG  CCAAGGACGA  GGTGTCCGAG  AGCCCGCCGC  CCTGCTCAAG  GCCAAAGACC  960
961   CTGAAGATCG  AAGCATGCCG  GGGCATGAAC  GAAGCGCTGG  AGAAGCAGCT  GCAGGAGCTG  1020
1021  GAAGACAAGC  AAAACGCCGA  CATCAGTGCT  ATGCAGGACA  CGATCAACAA  ACTAGAAAAT  1080
1081  GAATTGAGAA  CCACGAAGAG  TGAAATGGCA  CGATACCTAA  AAGAATACCA  AGACCTCCTC  1140
1141  AATGTGAAGA  TGGCTTTGGA  TATTGAGATT  GCAGCTTACA  GAAAACTCTT  GGAAGGTGAG  1200
1201  GAGACCCGAC  TGAGTTTCAC  CAGTGTGGGC  AGCATAACAA  GTGGCTACTC  CCAGAGCTCC  1260
1261  CAGGTCTTCG  GCCGGTCTGC  CTATGGCGGT  TTACAGACCA  GCTCCTACTT  GATGTCTGCC  1320
1321  CGCTCCTTCC  CGACCTACTA  CACCAGCCAC  GTGCAGGAAG  AGCAGATCGA  GGTGGAGGAG  1380
1381  ACCATTGAGG  CTGCTAAGGC  CGAGGAGGCC  AAGGACGAGC  CTCCCTCTGA  AGGGGAAGCT  1440
1441  GAGGAGGAGG  AGGAGAAGAA  GGAAGAGGGT  GAGGAAGAGG  AGGGAGCCGA  GGAAGAAGAA  1500
1501  GCTGCCAAGG  AAGAATCTGA  AGAGGTAAAG  GAGGAGGAAG  AAGAAGGAGG  TGAAGGTGAA  1560
1561  GAGGGAGAAG  AAACCAAAGA  AGCAGAAGAG  GATGAGAAGA  AAGATGAAGG  TGCTGGGGAG  1620
1621  GAACAGGCAA  CCAAGAAGAA  AGATTGA  1647

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mea-0340Mesocricetus auratus97.412e-91 287
LLPS-Chs-2623Chlorocebus sabaeus86.370.0 613
LLPS-Maf-0843Macaca fascicularis86.370.0 616
LLPS-Aim-4077Ailuropoda melanoleuca86.370.0 618
LLPS-Mal-0741Mandrillus leucophaeus86.370.0 616
LLPS-Paa-0983Papio anubis86.370.0 616
LLPS-Fec-3435Felis catus86.370.0 617
LLPS-Urm-4035Ursus maritimus86.370.0 617
LLPS-Man-3425Macaca nemestrina86.370.0 616
LLPS-Caf-3628Canis familiaris86.370.0 617
LLPS-Mam-4564Macaca mulatta86.370.0 616
LLPS-Gog-0807Gorilla gorilla86.150.0 615
LLPS-Cea-4295Cercocebus atys86.150.0 615
LLPS-Hos-2703Homo sapiens86.150.0 615
LLPS-Pap-3665Pan paniscus86.150.0 615
LLPS-Pat-4130Pan troglodytes86.150.0 615
LLPS-Nol-0953Nomascus leucogenys86.150.0 615
LLPS-Poa-1190Pongo abelii86.150.0 615
LLPS-Caj-4509Callithrix jacchus85.930.0 617
LLPS-Mup-3164Mustela putorius furo85.930.0 616
LLPS-Eqc-2587Equus caballus85.930.0 617
LLPS-Sus-1788Sus scrofa85.710.0 611
LLPS-Aon-3112Aotus nancymaae85.710.0 615
LLPS-Cap-4061Cavia porcellus85.680.0 608
LLPS-Tut-0250Tursiops truncatus85.490.0 611
LLPS-Bot-3887Bos taurus85.490.0 612
LLPS-Ran-2337Rattus norvegicus85.270.0 610
LLPS-Fud-3916Fukomys damarensis85.050.0 610
LLPS-Mum-4808Mus musculus85.050.0 607
LLPS-Rhb-2567Rhinopithecus bieti84.620.0 598
LLPS-Dio-4307Dipodomys ordii84.40.0 574
LLPS-Otg-2049Otolemur garnettii83.511e-162 475
LLPS-Ict-2522Ictidomys tridecemlineatus78.680.0 534
LLPS-Mod-1146Monodelphis domestica77.05e-134 404
LLPS-Loa-2430Loxodonta africana76.262e-170 500
LLPS-Gaga-2241Gallus gallus76.143e-153 451
LLPS-Meg-2687Meleagris gallopavo70.240.0 530
LLPS-Fia-3450Ficedula albicollis69.89e-179 523
LLPS-Pes-3726Pelodiscus sinensis68.752e-116 358
LLPS-Ora-1407Ornithorhynchus anatinus65.877e-150 449
LLPS-Lac-2411Latimeria chalumnae65.862e-163 484
LLPS-Myl-0998Myotis lucifugus65.89e-84 271
LLPS-Anc-2290Anolis carolinensis65.462e-131 402
LLPS-Xet-3040Xenopus tropicalis62.751e-155 464
LLPS-Tag-2936Taeniopygia guttata61.351e-141 427
LLPS-Leo-0978Lepisosteus oculatus59.482e-128 395
LLPS-Dar-3796Danio rerio56.352e-108 343
LLPS-Orn-3665Oreochromis niloticus55.992e-105 334
LLPS-Scm-2631Scophthalmus maximus54.522e-97 315
LLPS-Pof-1602Poecilia formosa53.982e-97 313
LLPS-Tar-0482Takifugu rubripes53.512e-96 310
LLPS-Xim-3822Xiphophorus maculatus52.847e-95 307
LLPS-Ten-1584Tetraodon nigroviridis52.759e-90 286
LLPS-Asm-0359Astyanax mexicanus52.29e-105 334
LLPS-Icp-2948Ictalurus punctatus50.458e-102 323
LLPS-Gaa-2366Gasterosteus aculeatus50.443e-108 345
LLPS-Orl-1697Oryzias latipes49.899e-106 338
LLPS-Cas-2282Carlito syrichta44.94e-52 190
LLPS-Sah-0821Sarcophilus harrisii43.942e-52 191
LLPS-Scf-3175Scleropages formosus43.586e-56 200
LLPS-Ova-3519Ovis aries43.441e-59 211
LLPS-Ere-0443Erinaceus europaeus43.024e-61 215
LLPS-Anp-0298Anas platyrhynchos41.09e-54 195
LLPS-Cii-0131Ciona intestinalis35.691e-40 158
LLPS-Cis-0564Ciona savignyi33.516e-38 150