• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Ora-0759

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Superoxide dismutase
Ensembl Gene: ENSOANG00000000632.3
Ensembl Protein: ENSOANP00000000986.1
Organism: Ornithorhynchus anatinus
Taxa ID: 9258
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION


Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblENSOANT00000000987.1ENSOANP00000000986.1
UniProtF7ENE6, F7ENE6_ORNAN

▼ SEQUENCE


Protein Sequence (FASTA)
1     ALCRALGRSA  RLVPALGCLG  SRQKHTLPDL  PYDYGALEPH  INAQIMQLHH  SKHHAAYVNN  60
61    LNVTEERYKE  ALAKGDVTTQ  VALQPALKFN  GGGHINHTIF  WTNLSPNGGG  EPKGELLEAI  120
121   KRDFGSFEKF  KEKLTAVSVG  VQGSGWGWLG  FDQEQGRLRV  AACSNQDPLQ  GTTGLVPLLG  180
181   IDVWEHAYYL  QYKNVRPDYL  KAIWNVISWE  NVTERYQACK  K  221
Nucleotide CDS Sequence (FASTA)
1     GCGCTGTGCC  GAGCGCTCGG  GAGGAGCGCT  CGGCTGGTGC  CGGCTTTGGG  CTGCTTGGGC  60
61    TCCAGGCAGA  AGCACACCCT  CCCTGATCTG  CCTTATGACT  ACGGCGCCCT  GGAACCCCAC  120
121   ATCAATGCCC  AGATCATGCA  GCTCCACCAC  AGCAAACATC  ACGCCGCTTA  CGTGAACAAC  180
181   CTGAACGTTA  CGGAGGAGAG  GTACAAGGAG  GCGCTGGCCA  AGGGTGATGT  TACAACTCAA  240
241   GTGGCGCTCC  AGCCCGCCCT  CAAGTTCAAC  GGTGGGGGTC  ATATCAACCA  CACCATTTTC  300
301   TGGACCAACC  TTAGTCCTAA  CGGCGGAGGA  GAACCCAAAG  GGGAGCTGCT  GGAAGCCATC  360
361   AAGAGGGACT  TTGGCTCCTT  CGAGAAGTTC  AAGGAGAAGC  TGACGGCAGT  CTCGGTGGGG  420
421   GTGCAGGGTT  CGGGCTGGGG  ATGGCTGGGC  TTCGACCAGG  AGCAAGGACG  CCTCCGGGTT  480
481   GCCGCTTGTT  CCAATCAGGA  CCCGCTGCAA  GGAACGACAG  GTCTGGTTCC  TCTGCTTGGA  540
541   ATCGATGTGT  GGGAGCACGC  TTATTATCTT  CAGTATAAAA  ATGTTCGGCC  CGATTATCTG  600
601   AAAGCTATCT  GGAACGTGAT  TAGCTGGGAG  AACGTAACCG  AAAGATATCA  AGCTTGCAAA  660
661   AAGTGA  666

▼ KEYWORD


ID
Family
Complete proteome
Metal-binding
Oxidoreductase
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Mitochondrion
Molecular Function
Metal ion binding
Molecular Function
Superoxide dismutase activity
Biological Process
Acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process
Age-dependent response to oxidative stress
Biological Process
Aging
Biological Process
Detection of oxygen
Biological Process
Erythrophore differentiation
Biological Process
Glutathione metabolic process
Biological Process
Heart development
Biological Process
Hemopoiesis
Biological Process
Intrinsic apoptotic signaling pathway in response to DNA damage
Biological Process
Intrinsic apoptotic signaling pathway in response to oxidative stress
Biological Process
Iron ion homeostasis
Biological Process
Liver development
Biological Process
Locomotory behavior
Biological Process
Negative regulation of fat cell differentiation
Biological Process
Negative regulation of fibroblast proliferation
Biological Process
Neuron development
Biological Process
Positive regulation of nitric oxide biosynthetic process
Biological Process
Post-embryonic development
Biological Process
Regulation of catalytic activity
Biological Process
Regulation of mitochondrial membrane potential
Biological Process
Regulation of transcription by RNA polymerase II
Biological Process
Release of cytochrome c from mitochondria
Biological Process
Respiratory electron transport chain
Biological Process
Response to activity
Biological Process
Response to axon injury
Biological Process
Response to gamma radiation
Biological Process
Response to hydrogen peroxide
Biological Process
Response to hyperoxia
Biological Process
Superoxide anion generation

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sus-3654Sus scrofa91.868e-137 390
LLPS-Tut-2261Tursiops truncatus90.413e-83 251
LLPS-Rhb-1379Rhinopithecus bieti90.054e-124 358
LLPS-Mod-3079Monodelphis domestica90.056e-138 393
LLPS-Dio-1499Dipodomys ordii89.774e-130 373
LLPS-Mal-4417Mandrillus leucophaeus89.712e-125 361
LLPS-Sah-3796Sarcophilus harrisii89.591e-136 390
LLPS-Poa-2391Pongo abelii89.261e-84 255
LLPS-Gog-3389Gorilla gorilla89.221e-124 359
LLPS-Mum-3317Mus musculus89.145e-132 378
LLPS-Fec-4800Felis catus88.949e-132 377
LLPS-Tag-0268Taeniopygia guttata88.734e-130 373
LLPS-Nol-4349Nomascus leucogenys88.695e-133 380
LLPS-Bot-3420Bos taurus88.486e-129 380
LLPS-Pap-1405Pan paniscus88.242e-132 379
LLPS-Man-3418Macaca nemestrina88.242e-132 379
LLPS-Ict-3138Ictidomys tridecemlineatus88.242e-133 381
LLPS-Mam-2558Macaca mulatta88.242e-132 379
LLPS-Mea-3165Mesocricetus auratus88.241e-132 380
LLPS-Maf-3216Macaca fascicularis88.242e-132 379
LLPS-Caf-1851Canis familiaris88.023e-131 376
LLPS-Loa-4455Loxodonta africana87.795e-129 370
LLPS-Hos-3981Homo sapiens87.786e-132 378
LLPS-Mup-0596Mustela putorius furo87.783e-131 376
LLPS-Ova-2193Ovis aries87.785e-132 378
LLPS-Pat-2387Pan troglodytes87.741e-125 362
LLPS-Cea-0886Cercocebus atys87.744e-125 361
LLPS-Paa-4346Papio anubis87.741e-125 362
LLPS-Otg-2176Otolemur garnettii87.564e-132 378
LLPS-Fia-0630Ficedula albicollis87.52e-102 301
LLPS-Eqc-3831Equus caballus87.334e-132 378
LLPS-Cap-1513Cavia porcellus87.336e-130 372
LLPS-Ran-2543Rattus norvegicus87.332e-129 372
LLPS-Pes-2792Pelodiscus sinensis87.328e-127 365
LLPS-Caj-2215Callithrix jacchus87.266e-124 358
LLPS-Meg-2719Meleagris gallopavo87.141e-125 362
LLPS-Fud-2667Fukomys damarensis86.884e-130 373
LLPS-Chs-1583Chlorocebus sabaeus86.885e-131 375
LLPS-Myl-3673Myotis lucifugus86.884e-131 376
LLPS-Urm-0207Ursus maritimus86.822e-130 374
LLPS-Cas-3974Carlito syrichta86.641e-128 369
LLPS-Aon-1447Aotus nancymaae86.491e-127 367
LLPS-Aim-3672Ailuropoda melanoleuca86.366e-129 370
LLPS-Anp-1233Anas platyrhynchos85.947e-107 313
LLPS-Gaga-0009Gallus gallus85.652e-129 371
LLPS-Orl-2921Oryzias latipes85.572e-119 346
LLPS-Scm-2590Scophthalmus maximus85.03e-118 343
LLPS-Anc-0885Anolis carolinensis84.443e-129 371
LLPS-Dar-4168Danio rerio83.11e-123 357
LLPS-Asm-1716Astyanax mexicanus83.11e-124 359
LLPS-Icp-3011Ictalurus punctatus83.16e-124 357
LLPS-Lac-3005Latimeria chalumnae82.163e-121 350
LLPS-Xet-3779Xenopus tropicalis81.613e-121 350
LLPS-Pof-1068Poecilia formosa80.893e-121 351
LLPS-Xim-2625Xiphophorus maculatus80.82e-120 349
LLPS-Gaa-3290Gasterosteus aculeatus80.096e-120 347
LLPS-Leo-2203Lepisosteus oculatus79.825e-122 353
LLPS-Orn-3955Oreochromis niloticus79.562e-121 351
LLPS-Tar-3948Takifugu rubripes79.174e-115 337
LLPS-Scf-1356Scleropages formosus78.671e-121 352
LLPS-Ten-1634Tetraodon nigroviridis78.224e-117 340
LLPS-Cii-1245Ciona intestinalis69.712e-95 285
LLPS-Cis-0843Ciona savignyi66.865e-75 231
LLPS-Cae-1955Caenorhabditis elegans64.93e-86 261
LLPS-Orc-4085Oryctolagus cuniculus64.437e-56 181
LLPS-Orgl-0651Oryza glumaepatula63.241e-2092.0
LLPS-Glm-0820Glycine max61.111e-68 217
LLPS-Thc-0055Theobroma cacao61.06e-70 220
LLPS-Brd-0037Brachypodium distachyon60.712e-70 221
LLPS-Via-0916Vigna angularis60.692e-54 180
LLPS-Phv-0799Phaseolus vulgaris60.414e-68 216
LLPS-Hea-1480Helianthus annuus60.36e-70 220
LLPS-Amt-1956Amborella trichopoda60.05e-55 181
LLPS-Prp-0589Prunus persica60.04e-69 220
LLPS-Mua-0793Musa acuminata60.02e-67 214
LLPS-Orp-0549Oryza punctata59.692e-68 216
LLPS-Dac-1161Daucus carota59.697e-68 215
LLPS-Met-1313Medicago truncatula59.691e-67 214
LLPS-Lep-2361Leersia perrieri59.699e-69 217
LLPS-Viv-2025Vitis vinifera59.53e-66 213
LLPS-Orm-0215Oryza meridionalis59.189e-68 214
LLPS-Orni-2188Oryza nivara59.181e-67 214
LLPS-Ori-0458Oryza indica59.181e-67 214
LLPS-Abg-1656Absidia glauca59.051e-70 236
LLPS-Gor-1691Gossypium raimondii59.05e-69 218
LLPS-Drm-1512Drosophila melanogaster58.962e-79 244
LLPS-Cus-0020Cucumis sativus58.726e-71 223
LLPS-Org-1641Oryza glaberrima58.599e-66 209
LLPS-Bro-0510Brassica oleracea58.542e-68 216
LLPS-Pot-2044Populus trichocarpa58.383e-68 215
LLPS-Art-0205Arabidopsis thaliana58.229e-71 222
LLPS-Arl-0089Arabidopsis lyrata58.221e-69 219
LLPS-Ors-0870Oryza sativa58.163e-67 213
LLPS-Hov-1803Hordeum vulgare58.081e-66 213
LLPS-Chr-0310Chlamydomonas reinhardtii57.877e-71 222
LLPS-Brn-3073Brassica napus57.823e-68 216
LLPS-Mae-2606Manihot esculenta57.84e-72 226
LLPS-Nia-2092Nicotiana attenuata56.764e-69 218
LLPS-Brr-2846Brassica rapa56.682e-68 216
LLPS-Spr-0643Sporisorium reilianum56.59e-67 212
LLPS-Sei-1106Setaria italica56.361e-68 217
LLPS-Sol-1779Solanum lycopersicum55.861e-67 214
LLPS-Sot-1895Solanum tuberosum55.863e-68 216
LLPS-Fuo-1585Fusarium oxysporum55.785e-60 194
LLPS-Orbr-1530Oryza brachyantha55.714e-69 218
LLPS-Sob-2452Sorghum bicolor55.667e-69 218
LLPS-Sem-2081Selaginella moellendorffii55.568e-65 206
LLPS-Fus-0188Fusarium solani55.41e-58 191
LLPS-Fuv-1222Fusarium verticillioides55.283e-59 192
LLPS-Coc-1801Corchorus capsularis55.04e-69 218
LLPS-Tra-1907Triticum aestivum55.05e-68 215
LLPS-Cog-0466Colletotrichum gloeosporioides54.772e-68 216
LLPS-Cogr-1481Colletotrichum graminicola54.777e-69 218
LLPS-Nec-1123Neurospora crassa54.736e-65 208
LLPS-Tru-1922Triticum urartu54.645e-53 180
LLPS-Coo-1133Colletotrichum orbiculare54.272e-62 201
LLPS-Zem-1410Zea mays53.852e-66 211
LLPS-Ved-1519Verticillium dahliae53.772e-66 211
LLPS-Cym-1120Cyanidioschyzon merolae53.545e-56 186
LLPS-Gas-0874Galdieria sulphuraria53.477e-66 209
LLPS-Scs-0310Sclerotinia sclerotiorum53.35e-67 213
LLPS-Aso-1140Aspergillus oryzae53.29e-65 207
LLPS-Beb-0833Beauveria bassiana53.189e-61 196
LLPS-Php-2211Physcomitrella patens52.942e-64 206
LLPS-Blg-1165Blumeria graminis52.763e-67 213
LLPS-Nef-1649Neosartorya fischeri52.741e-63 204
LLPS-Osl-1117Ostreococcus lucimarinus52.256e-68 215
LLPS-Usm-1437Ustilago maydis52.212e-68 216
LLPS-Tum-1090Tuber melanosporum51.795e-57 186
LLPS-Asn-0482Aspergillus nidulans51.764e-62 200
LLPS-Pug-1368Puccinia graminis51.51e-61 199
LLPS-Lem-1364Leptosphaeria maculans51.183e-62 201
LLPS-Asfu-1634Aspergillus fumigatus51.166e-64 205
LLPS-Crn-0165Cryptococcus neoformans51.118e-69 217
LLPS-Zyt-0294Zymoseptoria tritici50.453e-65 208
LLPS-Asni-0892Aspergillus niger50.238e-65 207
LLPS-Gag-0860Gaeumannomyces graminis50.231e-57 189
LLPS-Ast-1577Aspergillus terreus50.222e-64 206
LLPS-Pytr-1213Pyrenophora triticirepentis49.788e-64 204
LLPS-Mao-0416Magnaporthe oryzae49.774e-59 192
LLPS-Orb-0548Oryza barthii49.577e-60 196
LLPS-Put-0161Puccinia triticina49.55e-59 192
LLPS-Pyt-1266Pyrenophora teres49.333e-63 203
LLPS-Scp-1175Schizosaccharomyces pombe49.259e-54 178
LLPS-Phn-1050Phaeosphaeria nodorum48.883e-61 198
LLPS-Asc-0899Aspergillus clavatus48.875e-64 205
LLPS-Dos-1576Dothistroma septosporum48.644e-62 200
LLPS-Yal-1140Yarrowia lipolytica48.477e-51 171
LLPS-Orr-0245Oryza rufipogon48.182e-50 171
LLPS-Trr-0212Trichoderma reesei48.06e-55 181
LLPS-Trv-0978Trichoderma virens47.961e-55 183
LLPS-Mel-1050Melampsora laricipopulina46.79e-52 173
LLPS-Scj-0874Schizosaccharomyces japonicus46.152e-43 151
LLPS-Asg-1338Ashbya gossypii45.982e-50 170
LLPS-Asf-0382Aspergillus flavus45.699e-48 162
LLPS-Sac-1129Saccharomyces cerevisiae43.321e-49 168
LLPS-Kop-0507Komagataella pastoris42.537e-49 166
LLPS-Chc-0324Chondrus crispus40.483e-41 146