• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Lac-3005
SOD2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Superoxide dismutase
Gene Name: SOD2
Ensembl Gene: ENSLACG00000015527.1
Ensembl Protein: ENSLACP00000017630.1
Organism: Latimeria chalumnae
Taxa ID: 7897
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKRVKQIQIC  TVNMAPALSC  LGSRHKHSLP  DLPYDYGALE  PHISAEIMQL  HHSKHHATYV  60
61    NNLNIAEEKY  LEVLTKGDVT  AQVSLQPALR  FNGGGHINHT  IFWTNLSPSG  GGEPQGELNE  120
121   AIKRDFGSFE  KMKEKLTSIS  VGVQGSGWGW  LGFNKENGRL  QLASCPNQDP  LQGTTGLIPL  180
181   LGIDVWEHAY  YLQYKNVRPD  YLKAIWNVIN  WENVAERYRA  AKK  223
Nucleotide CDS Sequence (FASTA)
1     ATGGCTCCAG  CACTGAGCTG  CCTGGGCTCC  AGACACAAGC  ATAGTCTCCC  TGACCTGCCA  60
61    TATGACTATG  GTGCACTGGA  ACCTCACATC  AGTGCAGAAA  TCATGCAGCT  CCACCACAGC  120
121   AAGCATCATG  CTACCTATGT  CAACAACCTA  AACATTGCAG  AGGAAAAGTA  CTTGGAAGTA  180
181   CTAACTAAGG  GGGATGTTAC  AGCTCAAGTG  TCTCTACAGC  CTGCACTTCG  GTTCAATGGA  240
241   GGCGGCCACA  TTAACCACAC  CATTTTCTGG  ACCAACCTTT  CCCCGAGTGG  TGGAGGAGAA  300
301   CCTCAAGGAG  AGCTAAATGA  GGCTATCAAG  CGAGACTTTG  GCTCCTTTGA  GAAAATGAAG  360
361   GAGAAGCTGA  CTTCAATATC  AGTTGGTGTT  CAGGGCTCAG  GCTGGGGATG  GCTGGGCTTT  420
421   AACAAAGAGA  ATGGACGGCT  ACAGTTAGCC  TCTTGCCCCA  ATCAGGACCC  ACTGCAAGGA  480
481   ACAACAGGCC  TTATTCCACT  TCTTGGAATT  GATGTCTGGG  AGCATGCCTA  CTACCTACAG  540
541   TACAAGAATG  TTAGGCCTGA  CTACCTAAAA  GCTATATGGA  ATGTGATCAA  CTGGGAGAAT  600
601   GTAGCTGAGA  GATATCGAGC  AGCCAAAAAG  TAA  633

▼ KEYWORD

ID
Family
Complete proteome
Metal-binding
Oxidoreductase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Metal ion binding
Molecular Function
Superoxide dismutase activity
Biological Process
Innate immune response
Biological Process
Neutrophil homeostasis
Biological Process
Response to cadmium ion
Biological Process
Response to methylmercury

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-2391Pongo abelii87.251e-93 278
LLPS-Rhb-1379Rhinopithecus bieti87.067e-132 378
LLPS-Chs-1583Chlorocebus sabaeus86.676e-137 390
LLPS-Paa-4346Papio anubis86.573e-131 376
LLPS-Mal-4417Mandrillus leucophaeus86.571e-131 377
LLPS-Cea-0886Cercocebus atys86.571e-130 375
LLPS-Mod-3079Monodelphis domestica86.388e-139 395
LLPS-Sah-3796Sarcophilus harrisii86.384e-139 396
LLPS-Mam-2558Macaca mulatta86.194e-136 388
LLPS-Cap-1513Cavia porcellus86.198e-135 385
LLPS-Nol-4349Nomascus leucogenys86.196e-136 388
LLPS-Anc-0885Anolis carolinensis86.194e-135 386
LLPS-Maf-3216Macaca fascicularis86.194e-136 388
LLPS-Pat-2387Pan troglodytes86.071e-130 375
LLPS-Caj-2215Callithrix jacchus86.072e-129 372
LLPS-Gog-3389Gorilla gorilla86.079e-131 375
LLPS-Fia-0630Ficedula albicollis85.81e-112 327
LLPS-Man-3418Macaca nemestrina85.718e-135 385
LLPS-Pap-1405Pan paniscus85.712e-135 387
LLPS-Bot-3420Bos taurus85.716e-134 393
LLPS-Sus-3654Sus scrofa85.311e-136 390
LLPS-Caf-1851Canis familiaris85.244e-136 388
LLPS-Hos-3981Homo sapiens85.241e-134 385
LLPS-Meg-2719Meleagris gallopavo85.246e-133 380
LLPS-Ran-2543Rattus norvegicus85.245e-135 385
LLPS-Mum-3317Mus musculus85.243e-134 384
LLPS-Anp-1233Anas platyrhynchos85.02e-111 325
LLPS-Tut-2261Tursiops truncatus84.933e-90 269
LLPS-Dio-1499Dipodomys ordii84.832e-134 384
LLPS-Ict-3138Ictidomys tridecemlineatus84.765e-135 385
LLPS-Gaga-0009Gallus gallus84.762e-133 382
LLPS-Pes-2792Pelodiscus sinensis84.763e-132 379
LLPS-Otg-2176Otolemur garnettii84.762e-136 389
LLPS-Aon-1447Aotus nancymaae84.763e-131 376
LLPS-Mup-0596Mustela putorius furo84.582e-136 389
LLPS-Fec-4800Felis catus84.295e-134 383
LLPS-Fud-2667Fukomys damarensis84.291e-132 379
LLPS-Cas-3974Carlito syrichta83.817e-131 375
LLPS-Eqc-3831Equus caballus83.333e-133 381
LLPS-Tag-0268Taeniopygia guttata83.11e-133 382
LLPS-Mea-3165Mesocricetus auratus82.861e-132 379
LLPS-Ova-2193Ovis aries82.491e-134 384
LLPS-Myl-3673Myotis lucifugus82.382e-131 377
LLPS-Xet-3779Xenopus tropicalis82.354e-136 389
LLPS-Ora-0759Ornithorhynchus anatinus82.161e-134 385
LLPS-Scf-1356Scleropages formosus81.91e-130 375
LLPS-Urm-0207Ursus maritimus81.252e-136 389
LLPS-Aim-3672Ailuropoda melanoleuca81.252e-136 389
LLPS-Loa-4455Loxodonta africana81.118e-131 375
LLPS-Tar-3948Takifugu rubripes80.841e-129 374
LLPS-Dar-4168Danio rerio79.191e-133 382
LLPS-Ten-1634Tetraodon nigroviridis78.381e-130 374
LLPS-Icp-3011Ictalurus punctatus78.031e-134 385
LLPS-Pof-1068Poecilia formosa77.936e-131 375
LLPS-Leo-2203Lepisosteus oculatus77.382e-132 379
LLPS-Orl-2921Oryzias latipes77.133e-128 369
LLPS-Asm-1716Astyanax mexicanus77.134e-134 383
LLPS-Orn-3955Oreochromis niloticus76.586e-131 375
LLPS-Xim-2625Xiphophorus maculatus76.131e-128 370
LLPS-Scm-2590Scophthalmus maximus75.892e-128 370
LLPS-Gaa-3290Gasterosteus aculeatus73.452e-126 364
LLPS-Cii-1245Ciona intestinalis69.811e-109 321
LLPS-Cis-0843Ciona savignyi68.393e-88 265
LLPS-Orgl-0651Oryza glumaepatula66.181e-2195.1
LLPS-Drm-1512Drosophila melanogaster62.933e-95 284
LLPS-Cae-1955Caenorhabditis elegans62.861e-96 288
LLPS-Orc-4085Oryctolagus cuniculus62.422e-57 185
LLPS-Chr-0310Chlamydomonas reinhardtii61.222e-84 257
LLPS-Prp-0589Prunus persica60.911e-77 242
LLPS-Lep-2361Leersia perrieri60.618e-79 243
LLPS-Brd-0037Brachypodium distachyon60.22e-79 244
LLPS-Thc-0055Theobroma cacao60.22e-77 239
LLPS-Glm-0820Glycine max60.01e-77 240
LLPS-Viv-2025Vitis vinifera59.97e-75 234
LLPS-Pot-2044Populus trichocarpa59.793e-79 244
LLPS-Sol-1779Solanum lycopersicum59.693e-76 236
LLPS-Phv-0799Phaseolus vulgaris59.63e-77 239
LLPS-Orbr-1530Oryza brachyantha59.69e-78 240
LLPS-Nia-2092Nicotiana attenuata59.492e-75 234
LLPS-Gor-1691Gossypium raimondii59.393e-77 239
LLPS-Mae-2606Manihot esculenta59.336e-79 243
LLPS-Coc-1801Corchorus capsularis59.189e-77 238
LLPS-Tra-1907Triticum aestivum59.184e-78 241
LLPS-Hov-1803Hordeum vulgare59.189e-77 238
LLPS-Sei-1106Setaria italica59.181e-76 237
LLPS-Hea-1480Helianthus annuus59.187e-77 238
LLPS-Orm-0215Oryza meridionalis59.093e-77 239
LLPS-Ori-0458Oryza indica59.094e-77 238
LLPS-Orni-2188Oryza nivara59.094e-77 238
LLPS-Via-0916Vigna angularis58.864e-63 202
LLPS-Tru-1922Triticum urartu58.822e-62 204
LLPS-Art-0205Arabidopsis thaliana58.674e-77 239
LLPS-Dac-1161Daucus carota58.673e-76 236
LLPS-Orp-0549Oryza punctata58.592e-76 237
LLPS-Org-1641Oryza glaberrima58.53e-75 234
LLPS-Php-2211Physcomitrella patens58.53e-79 244
LLPS-Zem-1410Zea mays58.384e-75 233
LLPS-Met-1313Medicago truncatula58.213e-75 234
LLPS-Sob-2452Sorghum bicolor58.168e-76 235
LLPS-Sot-1895Solanum tuberosum58.162e-74 231
LLPS-Arl-0089Arabidopsis lyrata58.162e-75 234
LLPS-Mua-0793Musa acuminata58.161e-74 233
LLPS-Ors-0870Oryza sativa58.089e-77 238
LLPS-Amt-1956Amborella trichopoda57.063e-60 194
LLPS-Osl-1117Ostreococcus lucimarinus56.72e-81 249
LLPS-Spr-0643Sporisorium reilianum56.53e-79 244
LLPS-Abg-1656Absidia glauca56.51e-82 268
LLPS-Brn-3073Brassica napus56.56e-75 233
LLPS-Beb-0833Beauveria bassiana56.282e-70 221
LLPS-Bro-0510Brassica oleracea56.221e-74 232
LLPS-Nec-1123Neurospora crassa56.223e-77 240
LLPS-Sem-2081Selaginella moellendorffii56.079e-77 237
LLPS-Cus-0020Cucumis sativus56.025e-76 236
LLPS-Gas-0874Galdieria sulphuraria55.942e-79 244
LLPS-Brr-2846Brassica rapa55.834e-75 233
LLPS-Cym-1120Cyanidioschyzon merolae55.787e-66 211
LLPS-Fus-0188Fusarium solani55.563e-68 216
LLPS-Cogr-1481Colletotrichum graminicola55.281e-78 243
LLPS-Crn-0165Cryptococcus neoformans55.173e-82 251
LLPS-Cog-0466Colletotrichum gloeosporioides55.052e-77 239
LLPS-Fuo-1585Fusarium oxysporum54.777e-68 214
LLPS-Fuv-1222Fusarium verticillioides54.274e-67 212
LLPS-Coo-1133Colletotrichum orbiculare54.044e-72 226
LLPS-Mao-0416Magnaporthe oryzae53.544e-71 223
LLPS-Ved-1519Verticillium dahliae53.332e-76 237
LLPS-Scs-0310Sclerotinia sclerotiorum53.271e-76 237
LLPS-Gag-0860Gaeumannomyces graminis52.971e-69 220
LLPS-Aso-1140Aspergillus oryzae52.762e-71 224
LLPS-Nef-1649Neosartorya fischeri52.741e-71 225
LLPS-Asc-0899Aspergillus clavatus52.749e-74 230
LLPS-Asni-0892Aspergillus niger52.741e-71 225
LLPS-Ast-1577Aspergillus terreus52.711e-72 227
LLPS-Usm-1437Ustilago maydis52.71e-79 245
LLPS-Asfu-1634Aspergillus fumigatus52.174e-72 226
LLPS-Asn-0482Aspergillus nidulans51.763e-70 221
LLPS-Pug-1368Puccinia graminis51.498e-72 225
LLPS-Blg-1165Blumeria graminis51.368e-78 240
LLPS-Tum-1090Tuber melanosporum50.772e-68 216
LLPS-Lem-1364Leptosphaeria maculans50.752e-69 219
LLPS-Zyt-0294Zymoseptoria tritici50.234e-75 233
LLPS-Trv-0978Trichoderma virens50.03e-64 205
LLPS-Trr-0212Trichoderma reesei50.02e-64 205
LLPS-Orb-0548Oryza barthii49.583e-69 219
LLPS-Put-0161Puccinia triticina49.51e-69 219
LLPS-Asg-1338Ashbya gossypii49.073e-62 200
LLPS-Yal-1140Yarrowia lipolytica49.04e-62 200
LLPS-Dos-1576Dothistroma septosporum48.833e-70 221
LLPS-Scp-1175Schizosaccharomyces pombe48.763e-61 197
LLPS-Orr-0245Oryza rufipogon48.22e-60 196
LLPS-Kop-0507Komagataella pastoris47.833e-62 200
LLPS-Pytr-1213Pyrenophora triticirepentis47.793e-71 223
LLPS-Phn-1050Phaeosphaeria nodorum47.794e-72 226
LLPS-Pyt-1266Pyrenophora teres47.795e-71 223
LLPS-Scj-0874Schizosaccharomyces japonicus45.671e-51 172
LLPS-Sac-1129Saccharomyces cerevisiae45.371e-58 191
LLPS-Asf-0382Aspergillus flavus45.181e-58 190
LLPS-Mel-1050Melampsora laricipopulina44.294e-58 190
LLPS-Chc-0324Chondrus crispus41.96e-50 169