• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Myl-2980
CACUL1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: CACUL1
Ensembl Gene: ENSMLUG00000002860.2
Ensembl Protein: ENSMLUP00000002599.2
Organism: Myotis lucifugus
Taxa ID: 59463
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
PML nuclear body, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSMLUT00000002860.2ENSMLUP00000002599.2
UniProtG1NYU2, G1NYU2_MYOLU
GeneBankAAPE02042236

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEESMEEEEG  GSYEAMMDDQ  NHNNWEAAVD  GFRQPPPPPS  SIPAPAREPP  GGQLLAVPAV  60
61    SADRKGPKEG  LPLGPPPPEA  NGVIMMVKSC  DAAAAAAAKA  VPAPTPSSTI  NINTSTSKFL  120
121   MNVITIEDYK  STYWPKLDGA  IDQLLTQSPG  DYIPISYEQI  YSCVYKCVCQ  QHSEQMYSDL  180
181   IKKITNHLER  VSKELQASPP  DLYIERFNIA  LGQYMGALQS  IVPLFIYMNK  FYIETKLNRD  240
241   LKDDLIKLFT  EHVAEKHIYS  LMPLLLEAQS  TPFQVTPSTM  ANIVKGLYTL  RPEWVQMAPT  300
301   LFSKFIPNIL  PPAVESELSE  YAAQDQKLQR  ELMQNGFMSP  QSDQSRKRAG  DELAYNNSSA  360
361   CASSRGYR  368
Nucleotide CDS Sequence (FASTA)
1     ATGGAGGAAA  GCATGGAAGA  GGAGGAGGGG  GGCAGCTACG  AGGCAATGAT  GGACGACCAG  60
61    AACCACAACA  ACTGGGAGGC  TGCGGTGGAC  GGCTTCCGGC  AGCCCCCGCC  GCCCCCCTCG  120
121   TCGATCCCGG  CCCCGGCCCG  CGAGCCGCCG  GGGGGACAGC  TGCTGGCGGT  GCCGGCGGTC  180
181   TCGGCGGACA  GGAAAGGCCC  CAAGGAGGGG  CTCCCGTTGG  GGCCCCCCCC  CCCGGAGGCC  240
241   AATGGGGTGA  TCATGATGGT  GAAGAGCTGC  GACGCGGCCG  CCGCCGCCGC  GGCCAAGGCG  300
301   GTGCCCGCCC  CCACCCCCAG  CTCCACCATC  AACATCAACA  CCTCCACCTC  CAAGTTTTTA  360
361   ATGAATGTTA  TAACTATTGA  AGATTATAAG  AGCACATACT  GGCCAAAATT  GGATGGTGCC  420
421   ATAGATCAGC  TTTTAACCCA  GAGTCCTGGT  GACTATATCC  CCATATCCTA  TGAACAGATA  480
481   TACAGTTGTG  TGTATAAATG  TGTATGCCAG  CAGCACTCAG  AACAGATGTA  TAGTGATCTG  540
541   ATTAAGAAGA  TAACTAATCA  CTTAGAGAGA  GTCTCAAAGG  AGCTGCAGGC  CAGCCCTCCA  600
601   GATCTCTATA  TTGAAAGATT  TAATATAGCT  CTTGGACAGT  ATATGGGAGC  ATTGCAGAGC  660
661   ATTGTGCCTC  TTTTCATATA  TATGAATAAG  TTTTACATCG  AAACAAAACT  TAACAGAGAC  720
721   TTAAAAGATG  ACCTTATAAA  GCTGTTTACG  GAACATGTTG  CAGAAAAGCA  CATTTACAGC  780
781   CTAATGCCTT  TACTTTTAGA  AGCCCAGTCA  ACACCATTTC  AGGTCACACC  TTCAACTATG  840
841   GCAAATATTG  TGAAAGGCCT  GTACACTCTC  CGACCAGAGT  GGGTTCAGAT  GGCTCCAACT  900
901   CTATTTTCTA  AATTTATTCC  AAATATTCTC  CCTCCGGCGG  TGGAATCTGA  ACTTTCTGAA  960
961   TATGCTGCTC  AAGATCAGAA  ACTTCAAAGA  GAACTTATGC  AGAATGGTTT  TATGAGCCCC  1020
1021  CAGAGTGACC  AGTCCCGGAA  GAGAGCTGGG  GATGAGCTGG  CTTATAACAA  CTCATCAGCA  1080
1081  TGTGCGAGTT  CCAGAGGGTA  CAGATAG  1107

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Caf-1719Canis familiaris96.395e-176 497
LLPS-Dio-0418Dipodomys ordii95.977e-175 494
LLPS-Ora-3307Ornithorhynchus anatinus94.782e-173 490
LLPS-Tag-0338Taeniopygia guttata94.022e-174 493
LLPS-Fia-2113Ficedula albicollis94.022e-173 491
LLPS-Meg-0483Meleagris gallopavo93.989e-173 488
LLPS-Anp-0639Anas platyrhynchos93.575e-172 486
LLPS-Pes-0964Pelodiscus sinensis93.21e-171 486
LLPS-Sah-4039Sarcophilus harrisii92.84e-171 486
LLPS-Ict-4398Ictidomys tridecemlineatus92.241e-141 412
LLPS-Urm-3302Ursus maritimus91.396e-158 451
LLPS-Fud-2589Fukomys damarensis90.345e-179 507
LLPS-Bot-4850Bos taurus89.520.0 554
LLPS-Ova-2493Ovis aries88.950.0 552
LLPS-Otg-0928Otolemur garnettii88.710.0 525
LLPS-Mea-4550Mesocricetus auratus88.350.0 550
LLPS-Leo-2055Lepisosteus oculatus88.01e-108 326
LLPS-Eqc-2872Equus caballus87.354e-178 510
LLPS-Loa-2032Loxodonta africana87.290.0 560
LLPS-Caj-4650Callithrix jacchus86.760.0 558
LLPS-Cea-2984Cercocebus atys86.760.0 557
LLPS-Hos-2427Homo sapiens86.760.0 556
LLPS-Mup-3713Mustela putorius furo86.550.0 556
LLPS-Paa-4769Papio anubis86.480.0 558
LLPS-Mal-3866Mandrillus leucophaeus86.480.0 558
LLPS-Chs-3213Chlorocebus sabaeus86.480.0 558
LLPS-Rhb-4214Rhinopithecus bieti86.480.0 558
LLPS-Fec-3437Felis catus86.480.0 555
LLPS-Man-2844Macaca nemestrina86.480.0 558
LLPS-Nol-2978Nomascus leucogenys86.20.0 552
LLPS-Pat-4560Pan troglodytes86.20.0 556
LLPS-Cas-0673Carlito syrichta85.663e-145 421
LLPS-Maf-1760Macaca fascicularis85.630.0 558
LLPS-Sus-1105Sus scrofa85.630.0 550
LLPS-Mam-0279Macaca mulatta85.350.0 558
LLPS-Lac-2724Latimeria chalumnae84.861e-157 453
LLPS-Aon-4429Aotus nancymaae83.483e-180 512
LLPS-Ran-1858Rattus norvegicus83.470.0 541
LLPS-Gog-0652Gorilla gorilla83.191e-179 511
LLPS-Mum-4474Mus musculus81.820.0 538
LLPS-Cap-1178Cavia porcellus81.362e-178 507
LLPS-Orc-0511Oryctolagus cuniculus80.852e-176 502
LLPS-Mod-2380Monodelphis domestica80.582e-171 490
LLPS-Poa-2013Pongo abelii78.033e-169 483
LLPS-Scf-0837Scleropages formosus77.782e-136 404
LLPS-Xet-1626Xenopus tropicalis75.924e-125 370
LLPS-Pap-4081Pan paniscus75.01e-143 417
LLPS-Anc-1129Anolis carolinensis72.654e-163 469
LLPS-Gaga-2868Gallus gallus70.69e-166 476
LLPS-Dar-4277Danio rerio67.891e-106 320
LLPS-Icp-0512Ictalurus punctatus64.986e-95 289
LLPS-Gaa-2974Gasterosteus aculeatus64.574e-81 254
LLPS-Orn-3551Oreochromis niloticus64.262e-110 330
LLPS-Scm-3730Scophthalmus maximus64.262e-107 326
LLPS-Pof-4075Poecilia formosa64.266e-106 322
LLPS-Xim-3916Xiphophorus maculatus63.48e-105 319
LLPS-Orl-3795Oryzias latipes61.283e-103 315
LLPS-Ten-0191Tetraodon nigroviridis60.854e-104 314
LLPS-Tar-3425Takifugu rubripes60.092e-88 272
LLPS-Art-2074Arabidopsis thaliana29.064e-0962.4
LLPS-Cii-1981Ciona intestinalis28.693e-30 122
LLPS-Viv-0493Vitis vinifera27.834e-0962.4
LLPS-Brn-1824Brassica napus27.351e-0860.8
LLPS-Bro-1261Brassica oleracea27.351e-0860.8
LLPS-Brr-2600Brassica rapa27.351e-0860.8
LLPS-Orni-0125Oryza nivara26.672e-0757.0
LLPS-Ori-1793Oryza indica26.672e-0757.0
LLPS-Org-1080Oryza glaberrima26.672e-0757.0
LLPS-Orm-1060Oryza meridionalis26.672e-0757.0
LLPS-Ors-0115Oryza sativa26.672e-0757.0
LLPS-Orp-1289Oryza punctata26.674e-0755.8
LLPS-Orbr-0720Oryza brachyantha26.472e-0757.0
LLPS-Sem-0550Selaginella moellendorffii26.424e-0859.3
LLPS-Glm-0037Glycine max26.232e-0963.5
LLPS-Phv-1998Phaseolus vulgaris26.232e-0963.2
LLPS-Cus-0437Cucumis sativus26.095e-0858.9
LLPS-Sot-0171Solanum tuberosum26.096e-0962.0
LLPS-Sol-0685Solanum lycopersicum26.095e-0962.0
LLPS-Lep-0646Leersia perrieri25.715e-0755.8
LLPS-Met-0204Medicago truncatula25.685e-0962.0
LLPS-Vir-0781Vigna radiata25.684e-0962.4
LLPS-Arl-1381Arabidopsis lyrata25.582e-0963.2
LLPS-Gor-0137Gossypium raimondii25.421e-1170.1
LLPS-Cis-1580Ciona savignyi25.234e-0652.8
LLPS-Hea-2226Helianthus annuus25.222e-0757.4
LLPS-Tra-2282Triticum aestivum24.89e-0858.2
LLPS-Tru-0911Triticum urartu24.89e-0858.2
LLPS-Zem-0882Zea mays24.81e-0757.8
LLPS-Prp-0464Prunus persica24.585e-1065.1
LLPS-Thc-0960Theobroma cacao24.292e-0963.5
LLPS-Sei-0748Setaria italica24.01e-0757.4
LLPS-Orgl-1064Oryza glumaepatula24.02e-0757.4
LLPS-Orb-1813Oryza barthii24.02e-0757.0
LLPS-Orr-0358Oryza rufipogon24.02e-0757.0
LLPS-Mae-1114Manihot esculenta23.733e-1065.9
LLPS-Pot-1419Populus trichocarpa23.731e-0963.9
LLPS-Via-0963Vigna angularis23.482e-0756.6
LLPS-Nia-1579Nicotiana attenuata23.163e-1168.9
LLPS-Amt-1151Amborella trichopoda22.756e-1064.7
LLPS-Sob-0187Sorghum bicolor22.498e-0858.5
LLPS-Brd-1128Brachypodium distachyon22.356e-0858.5
LLPS-Mua-1882Musa acuminata21.434e-1065.5
LLPS-Php-0577Physcomitrella patens20.363e-0859.7
LLPS-Abg-1263Absidia glauca17.87e-0652.0