• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Man-2844
CACUL1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: CACUL1
Ensembl Gene: ENSMNEG00000035853.1
Ensembl Protein: ENSMNEP00000024626.1
Organism: Macaca nemestrina
Taxa ID: 9545
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
PML nuclear body, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEESMEEEEG  GSYEAMMDDQ  NHNNWEAAVD  GFRQPLPPPP  PPSSIPAPAR  EPPGGQLLAV  60
61    PAVSVDRKGP  KEGLPMGPPP  PPEANGVIMM  LKSCDAAAAV  AKAAPAPTAS  STININTSTS  120
121   KFLMNVITIE  DYKSTYWPKL  DGAIDQLLTQ  SPGDYIPISY  EQIYSCVYKC  VCQQHSEQMY  180
181   SDLIKKITNH  LERVSKELQA  SPPDLYIERF  NIALGQYMGA  LQSIVPLFIY  MNKFYIETKL  240
241   NRDLKDDLIK  LFTEHVAEKH  IYSLMPLLLE  AQSTPFQVTP  STMANIVKGL  YTLRPEWVQM  300
301   APTLFSKFIP  NILPPAVESE  LSEYAAQDQK  FQRELIQNGF  TRGDQSRKRA  GDELAYNSSS  360
361   ACASSRGYR  369
Nucleotide CDS Sequence (FASTA)
1     ATGGAGGAAA  GCATGGAAGA  GGAGGAGGGG  GGCAGCTACG  AGGCGATGAT  GGACGACCAG  60
61    AACCACAACA  ACTGGGAGGC  TGCGGTGGAC  GGCTTCCGGC  AGCCCCTGCC  ACCCCCACCG  120
121   CCCCCCTCTT  CGATCCCGGC  CCCTGCCCGA  GAGCCTCCAG  GGGGGCAGCT  GCTGGCGGTG  180
181   CCCGCGGTCT  CCGTGGACAG  GAAAGGCCCC  AAGGAGGGTC  TCCCGATGGG  GCCGCCGCCA  240
241   CCGCCTGAGG  CTAATGGGGT  GATCATGATG  TTGAAGAGCT  GCGACGCGGC  CGCCGCCGTG  300
301   GCCAAGGCGG  CCCCCGCCCC  CACCGCCAGC  TCCACCATCA  ACATCAACAC  CTCCACCTCC  360
361   AAGTTCTTAA  TGAATGTTAT  AACTATTGAA  GATTATAAGA  GCACATACTG  GCCAAAATTG  420
421   GATGGTGCCA  TAGATCAACT  TTTAACTCAG  AGTCCTGGTG  ACTATATCCC  CATATCCTAT  480
481   GAACAGATAT  ACAGTTGTGT  GTATAAATGT  GTATGCCAGC  AGCACTCGGA  ACAGATGTAT  540
541   AGTGATCTGA  TTAAAAAGAT  AACTAATCAC  TTAGAGAGAG  TCTCGAAGGA  GCTGCAGGCC  600
601   AGCCCTCCAG  ATCTCTATAT  TGAAAGATTT  AATATAGCTC  TTGGACAATA  TATGGGAGCA  660
661   TTGCAGAGCA  TTGTGCCTCT  TTTCATATAT  ATGAATAAGT  TTTACATCGA  AACCAAGCTT  720
721   AACAGAGACT  TAAAAGATGA  CCTTATAAAG  CTGTTTACGG  AACATGTTGC  AGAAAAGCAC  780
781   ATTTACAGCC  TAATGCCTTT  ACTTTTAGAA  GCCCAATCAA  CACCATTTCA  GGTCACACCT  840
841   TCAACTATGG  CAAATATTGT  GAAAGGCCTG  TATACCCTCA  GACCAGAGTG  GGTTCAGATG  900
901   GCTCCAACTC  TATTTTCTAA  ATTTATTCCA  AACATTCTCC  CTCCGGCGGT  GGAATCTGAA  960
961   CTTTCTGAAT  ATGCTGCTCA  AGATCAGAAA  TTTCAAAGAG  AACTTATACA  GAATGGTTTT  1020
1021  ACAAGAGGTG  ACCAGTCCCG  GAAGAGAGCT  GGGGATGAGT  TGGCTTATAA  CAGTTCGTCA  1080
1081  GCGTGTGCAA  GTTCCAGGGG  GTACAGATAG  1110

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Paa-4769Papio anubis100.00.0 589
LLPS-Mal-3866Mandrillus leucophaeus100.00.0 589
LLPS-Pat-4560Pan troglodytes99.720.0 588
LLPS-Hos-2427Homo sapiens99.720.0 588
LLPS-Mam-0279Macaca mulatta99.720.0 590
LLPS-Cea-2984Cercocebus atys99.720.0 588
LLPS-Chs-3213Chlorocebus sabaeus99.720.0 590
LLPS-Rhb-4214Rhinopithecus bieti99.430.0 590
LLPS-Nol-2978Nomascus leucogenys99.430.0 584
LLPS-Maf-1760Macaca fascicularis99.430.0 590
LLPS-Caj-4650Callithrix jacchus98.860.0 585
LLPS-Caf-1719Canis familiaris98.790.0 510
LLPS-Cas-0673Carlito syrichta98.565e-151 435
LLPS-Otg-0928Otolemur garnettii98.420.0 548
LLPS-Dio-0418Dipodomys ordii98.376e-180 506
LLPS-Fec-3437Felis catus98.010.0 584
LLPS-Eqc-2872Equus caballus97.850.0 528
LLPS-Sus-1105Sus scrofa97.730.0 577
LLPS-Loa-2032Loxodonta africana97.440.0 575
LLPS-Ora-3307Ornithorhynchus anatinus96.764e-178 502
LLPS-Gog-0652Gorilla gorilla96.490.0 536
LLPS-Fia-2113Ficedula albicollis95.981e-177 503
LLPS-Tag-0338Taeniopygia guttata95.987e-179 504
LLPS-Aon-4429Aotus nancymaae95.910.0 534
LLPS-Fud-2589Fukomys damarensis95.490.0 521
LLPS-Meg-0483Meleagris gallopavo95.144e-176 497
LLPS-Ict-4398Ictidomys tridecemlineatus94.931e-146 425
LLPS-Mup-3713Mustela putorius furo94.630.0 580
LLPS-Pes-0964Pelodiscus sinensis94.354e-175 494
LLPS-Anp-0639Anas platyrhynchos94.331e-174 493
LLPS-Sah-4039Sarcophilus harrisii93.952e-174 494
LLPS-Urm-3302Ursus maritimus92.981e-160 458
LLPS-Poa-2013Pongo abelii91.480.0 514
LLPS-Anc-1129Anolis carolinensis90.763e-166 478
LLPS-Mum-4474Mus musculus90.560.0 562
LLPS-Ran-1858Rattus norvegicus90.560.0 564
LLPS-Myl-2980Myotis lucifugus88.170.0 558
LLPS-Leo-2055Lepisosteus oculatus88.01e-108 326
LLPS-Bot-4850Bos taurus86.970.0 560
LLPS-Ova-2493Ovis aries86.970.0 562
LLPS-Orc-0511Oryctolagus cuniculus86.760.0 521
LLPS-Mea-4550Mesocricetus auratus86.360.0 565
LLPS-Lac-2724Latimeria chalumnae85.542e-160 461
LLPS-Cap-1178Cavia porcellus84.750.0 521
LLPS-Mod-2380Monodelphis domestica83.386e-175 499
LLPS-Scf-0837Scleropages formosus78.81e-139 412
LLPS-Pap-4081Pan paniscus78.295e-148 428
LLPS-Xet-1626Xenopus tropicalis77.377e-129 379
LLPS-Gaga-2868Gallus gallus69.638e-169 484
LLPS-Dar-4277Danio rerio67.272e-107 321
LLPS-Pof-4075Poecilia formosa64.818e-108 327
LLPS-Scm-3730Scophthalmus maximus64.812e-109 330
LLPS-Orn-3551Oreochromis niloticus64.812e-112 335
LLPS-Gaa-2974Gasterosteus aculeatus64.573e-81 254
LLPS-Icp-0512Ictalurus punctatus64.382e-95 290
LLPS-Xim-3916Xiphophorus maculatus63.959e-107 324
LLPS-Orl-3795Oryzias latipes61.84e-105 319
LLPS-Ten-0191Tetraodon nigroviridis61.377e-106 318
LLPS-Tar-3425Takifugu rubripes59.638e-88 271
LLPS-Art-2074Arabidopsis thaliana29.064e-0962.4
LLPS-Cii-1981Ciona intestinalis28.636e-29 119
LLPS-Viv-0493Vitis vinifera27.834e-0962.4
LLPS-Brr-2600Brassica rapa27.351e-0860.8
LLPS-Bro-1261Brassica oleracea27.351e-0860.8
LLPS-Brn-1824Brassica napus27.351e-0860.8
LLPS-Orp-1289Oryza punctata26.674e-0755.8
LLPS-Ors-0115Oryza sativa26.672e-0757.0
LLPS-Orm-1060Oryza meridionalis26.672e-0757.0
LLPS-Org-1080Oryza glaberrima26.672e-0757.0
LLPS-Ori-1793Oryza indica26.672e-0757.0
LLPS-Orni-0125Oryza nivara26.672e-0757.0
LLPS-Orbr-0720Oryza brachyantha26.472e-0757.0
LLPS-Sem-0550Selaginella moellendorffii26.425e-0858.9
LLPS-Phv-1998Phaseolus vulgaris26.232e-0963.5
LLPS-Sol-0685Solanum lycopersicum26.096e-0962.0
LLPS-Sot-0171Solanum tuberosum26.096e-0962.0
LLPS-Cus-0437Cucumis sativus26.095e-0858.9
LLPS-Lep-0646Leersia perrieri25.714e-0755.8
LLPS-Vir-0781Vigna radiata25.683e-0962.8
LLPS-Met-0204Medicago truncatula25.685e-0962.4
LLPS-Arl-1381Arabidopsis lyrata25.583e-0962.8
LLPS-Cis-1580Ciona savignyi25.234e-0652.8
LLPS-Hea-2226Helianthus annuus25.222e-0757.4
LLPS-Glm-0037Glycine max25.09e-1064.3
LLPS-Zem-0882Zea mays24.81e-0758.2
LLPS-Prp-0464Prunus persica24.585e-1065.1
LLPS-Gor-0137Gossypium raimondii24.199e-1270.9
LLPS-Orr-0358Oryza rufipogon24.02e-0757.4
LLPS-Orb-1813Oryza barthii24.02e-0757.4
LLPS-Orgl-1064Oryza glumaepatula24.01e-0757.4
LLPS-Sei-0748Setaria italica24.01e-0757.8
LLPS-Mae-1114Manihot esculenta23.733e-1065.9
LLPS-Via-0963Vigna angularis23.483e-0756.6
LLPS-Thc-0960Theobroma cacao23.261e-0964.3
LLPS-Nia-1579Nicotiana attenuata23.163e-1168.9
LLPS-Pot-1419Populus trichocarpa22.798e-1064.7
LLPS-Amt-1151Amborella trichopoda22.757e-1064.7
LLPS-Tru-0911Triticum urartu21.955e-0858.9
LLPS-Tra-2282Triticum aestivum21.955e-0858.9
LLPS-Brd-1128Brachypodium distachyon21.842e-0860.1
LLPS-Sob-0187Sorghum bicolor21.466e-0858.5
LLPS-Mua-1882Musa acuminata21.434e-1065.5
LLPS-Php-0577Physcomitrella patens20.363e-0859.3
LLPS-Abg-1263Absidia glauca18.222e-0653.9