LLPS-Mum-4507
Tubg2

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tubulin gamma-2 chain; Gamma-2-tubulin
Gene Name: Tubg2
Ensembl Gene: ENSMUSG00000045007.9
Ensembl Protein: ENSMUSP00000045901.9
Organism: Mus musculus
Taxa ID: 10090
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ FUNCTION

Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPREIITLQL  GQCGNQIGFE  FWKQLCAEHG  ISPEGIVEEF  ATEGTDRKDV  FFYQADDEHY  60
61    IPRAVLLDLE  PRVIHSILNS  SYAKLYNPEN  IYLSEHGGGA  GNNWGRGFSQ  GEKIHEDIFD  120
121   IIDREADGSD  SLEGFVLCHS  IAGGTGSGLG  SYLLERLNDR  YPKKLVQTYS  VFPNQDEMSD  180
181   VVVQPYNSLL  TLKRLTQNAD  CVVVLDNTAL  NRIATDRLHI  QNPSFSQINQ  LVSTIMSAST  240
241   TTLRYPGYMN  NDLIGLIASL  IPTPRLHFLM  TGYTPLTTDQ  SVASVRKTTV  LDVMRRLLQP  300
301   KNVMVSTGRD  RQTNHCYIAI  LNIIQGEVDP  TQVHKSLQRI  RERKLANFIP  WGPASIQVAL  360
361   SRKSPYLPSA  HRVSGLMMAN  HTSISSLFES  SCQQYDKLWK  RGAFLEQFRK  EDIFKDNFEE  420
421   MHRSREVVQE  LIDEYHAATR  PDYISWGTQE  Q  451
Nucleotide CDS Sequence (FASTA)
1     ATGCCCCGGG  AGATCATCAC  CCTGCAGCTG  GGCCAGTGCG  GCAACCAGAT  TGGGTTCGAG  60
61    TTCTGGAAAC  AGCTGTGTGC  TGAACATGGA  ATCAGCCCCG  AGGGCATCGT  AGAGGAGTTC  120
121   GCCACCGAGG  GCACTGACCG  AAAGGATGTC  TTTTTCTACC  AGGCAGATGA  TGAGCACTAC  180
181   ATCCCCCGGG  CTGTGCTGCT  GGACCTGGAG  CCCCGGGTGA  TCCATTCCAT  CCTCAACTCC  240
241   TCCTATGCTA  AGCTCTACAA  CCCGGAGAAC  ATCTACCTGT  CGGAGCATGG  CGGAGGAGCT  300
301   GGCAACAACT  GGGGCAGAGG  ATTCTCCCAG  GGTGAGAAAA  TTCACGAGGA  CATCTTTGAC  360
361   ATTATAGACC  GAGAAGCAGA  TGGAAGTGAC  AGTCTAGAGG  GATTTGTGCT  ATGTCACTCC  420
421   ATTGCTGGGG  GGACAGGTTC  TGGTCTGGGC  TCCTACCTCT  TAGAGCGACT  GAACGACAGG  480
481   TACCCCAAGA  AATTGGTGCA  GACATACTCA  GTGTTTCCCA  ACCAGGACGA  GATGAGTGAT  540
541   GTAGTGGTCC  AGCCCTACAA  CTCCCTCCTC  ACACTAAAGA  GGCTGACCCA  GAATGCGGAC  600
601   TGCGTGGTGG  TGCTGGACAA  CACAGCCCTG  AACCGGATCG  CCACAGACCG  CCTACACATC  660
661   CAGAACCCAT  CCTTCTCCCA  GATCAACCAG  CTGGTGTCCA  CCATCATGTC  AGCCAGCACC  720
721   ACCACCCTGC  GCTACCCTGG  ATACATGAAC  AATGACCTCA  TCGGCCTCAT  CGCCTCGCTC  780
781   ATTCCCACCC  CTCGGCTCCA  CTTCCTCATG  ACTGGCTACA  CCCCCCTCAC  CACGGACCAG  840
841   TCAGTGGCCA  GTGTGAGGAA  GACAACAGTC  CTGGATGTCA  TGAGGCGCCT  GCTACAGCCC  900
901   AAGAATGTGA  TGGTGTCCAC  AGGTCGGGAT  CGTCAGACCA  ACCACTGCTA  CATCGCCATC  960
961   CTCAACATCA  TCCAGGGAGA  GGTAGACCCC  ACCCAGGTCC  ACAAGAGCCT  GCAGAGGATC  1020
1021  CGGGAAAGGA  AACTGGCCAA  CTTCATTCCC  TGGGGCCCAG  CCAGCATCCA  GGTGGCCCTG  1080
1081  TCAAGGAAGT  CTCCCTACCT  GCCCTCAGCC  CACCGGGTCA  GCGGGCTCAT  GATGGCCAAC  1140
1141  CACACCAGTA  TCTCCTCGCT  TTTTGAAAGT  TCCTGCCAGC  AGTATGACAA  ACTGTGGAAG  1200
1201  CGGGGGGCCT  TCCTGGAACA  GTTTCGCAAG  GAGGACATCT  TCAAGGACAA  CTTTGAGGAG  1260
1261  ATGCACAGAT  CGAGGGAGGT  GGTGCAGGAA  CTCATTGACG  AGTACCACGC  GGCCACCCGG  1320
1321  CCGGACTACA  TCTCCTGGGG  TACCCAGGAG  CAGTGA  1356

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Cytoskeleton
GTP-binding
Microtubule
Nucleotide-binding
Phosphoprotein
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Centrosome
Cellular Component
Cytoplasm
Cellular Component
Cytoplasmic microtubule
Cellular Component
Gamma-tubulin complex
Cellular Component
Microtubule
Cellular Component
Nucleus
Cellular Component
Pericentriolar material
Cellular Component
Spindle
Cellular Component
Spindle microtubule
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Structural constituent of cytoskeleton
Biological Process
Cytoplasmic microtubule organization
Biological Process
Meiotic spindle organization
Biological Process
Microtubule cytoskeleton organization
Biological Process
Microtubule nucleation
Biological Process
Microtubule-based process
Biological Process
Mitotic cell cycle
Biological Process
Mitotic sister chromatid segregation
Biological Process
Mitotic spindle organization

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ora-0381Ornithorhynchus anatinus99.523e-143 420
LLPS-Mea-0857Mesocricetus auratus99.143e-144 421
LLPS-Eqc-0915Equus caballus98.970.0 738
LLPS-Orc-1141Oryctolagus cuniculus98.670.0 871
LLPS-Gaga-0347Gallus gallus98.450.0 730
LLPS-Cap-1070Cavia porcellus98.450.0 866
LLPS-Bot-1065Bos taurus98.230.0 863
LLPS-Scf-1156Scleropages formosus98.20.0 621
LLPS-Myl-0231Myotis lucifugus98.00.0 861
LLPS-Sus-0085Sus scrofa98.00.0 861
LLPS-Ova-0913Ovis aries97.930.0 827
LLPS-Loa-0276Loxodonta africana97.780.0 858
LLPS-Mup-0393Mustela putorius furo97.780.0 858
LLPS-Poa-2281Pongo abelii97.560.0 856
LLPS-Man-0700Macaca nemestrina97.560.0 857
LLPS-Fec-0029Felis catus97.560.0 857
LLPS-Hos-2536Homo sapiens97.560.0 857
LLPS-Urm-0893Ursus maritimus97.560.0 857
LLPS-Aim-1133Ailuropoda melanoleuca97.560.0 857
LLPS-Mal-2588Mandrillus leucophaeus97.560.0 857
LLPS-Chs-0617Chlorocebus sabaeus97.560.0 857
LLPS-Maf-0987Macaca fascicularis97.560.0 857
LLPS-Otg-1161Otolemur garnettii96.90.0 853
LLPS-Pat-0067Pan troglodytes96.90.0 853
LLPS-Paa-0651Papio anubis96.90.0 853
LLPS-Cea-1755Cercocebus atys96.90.0 853
LLPS-Ict-0551Ictidomys tridecemlineatus96.670.0 852
LLPS-Caf-1424Canis familiaris96.670.0 850
LLPS-Ran-0496Rattus norvegicus96.670.0 852
LLPS-Dio-0051Dipodomys ordii96.670.0 852
LLPS-Tut-0954Tursiops truncatus96.670.0 851
LLPS-Fia-0161Ficedula albicollis96.230.0 848
LLPS-Dar-1612Danio rerio96.010.0 846
LLPS-Icp-0759Ictalurus punctatus96.010.0 843
LLPS-Pes-0676Pelodiscus sinensis95.860.0 813
LLPS-Rhb-1017Rhinopithecus bieti95.650.0 849
LLPS-Caj-0526Callithrix jacchus95.650.0 849
LLPS-Lac-2287Latimeria chalumnae95.570.0 844
LLPS-Leo-2832Lepisosteus oculatus95.570.0 842
LLPS-Anp-1399Anas platyrhynchos95.480.0 731
LLPS-Tag-0643Taeniopygia guttata95.470.0 730
LLPS-Cas-1786Carlito syrichta95.220.0 845
LLPS-Asm-0993Astyanax mexicanus95.184e-169 491
LLPS-Gaa-1065Gasterosteus aculeatus94.90.0 834
LLPS-Orl-0832Oryzias latipes94.90.0 836
LLPS-Scm-2656Scophthalmus maximus94.680.0 833
LLPS-Xim-1680Xiphophorus maculatus94.680.0 833
LLPS-Pap-0259Pan paniscus94.420.0 847
LLPS-Gog-0270Gorilla gorilla94.420.0 847
LLPS-Nol-1586Nomascus leucogenys94.210.0 845
LLPS-Mam-0431Macaca mulatta94.180.0 844
LLPS-Mod-0311Monodelphis domestica94.180.0 843
LLPS-Tar-2008Takifugu rubripes94.010.0 826
LLPS-Sah-0982Sarcophilus harrisii93.980.0 843
LLPS-Ten-0091Tetraodon nigroviridis93.350.0 817
LLPS-Anc-0461Anolis carolinensis92.90.0 815
LLPS-Pof-0468Poecilia formosa92.790.0 817
LLPS-Aon-0731Aotus nancymaae92.460.0 827
LLPS-Orn-3626Oreochromis niloticus91.630.0 824
LLPS-Xet-0488Xenopus tropicalis88.960.0 768
LLPS-Cii-0525Ciona intestinalis81.210.0 735
LLPS-Cis-0841Ciona savignyi80.710.0 735
LLPS-Drm-0146Drosophila melanogaster77.970.0 702
LLPS-Sem-0023Selaginella moellendorffii75.550.0 662
LLPS-Php-0956Physcomitrella patens75.330.0 661
LLPS-Amt-0123Amborella trichopoda74.830.0 658
LLPS-Thc-0023Theobroma cacao74.450.0 647
LLPS-Mae-0092Manihot esculenta74.170.0 650
LLPS-Gor-2337Gossypium raimondii74.170.0 652
LLPS-Viv-0719Vitis vinifera74.170.0 650
LLPS-Orbr-0545Oryza brachyantha73.950.0 652
LLPS-Pot-2099Populus trichocarpa73.950.0 650
LLPS-Cus-0741Cucumis sativus73.950.0 649
LLPS-Glm-2540Glycine max73.950.0 650
LLPS-Prp-0253Prunus persica73.890.0 639
LLPS-Orb-1340Oryza barthii73.890.0 649
LLPS-Org-0740Oryza glaberrima73.730.0 651
LLPS-Coc-1258Corchorus capsularis73.730.0 647
LLPS-Orm-0449Oryza meridionalis73.730.0 652
LLPS-Orr-0092Oryza rufipogon73.730.0 652
LLPS-Ors-0312Oryza sativa73.730.0 651
LLPS-Arl-2592Arabidopsis lyrata73.730.0 647
LLPS-Brd-1944Brachypodium distachyon73.730.0 649
LLPS-Met-0533Medicago truncatula73.730.0 649
LLPS-Lep-1121Leersia perrieri73.730.0 651
LLPS-Orgl-0228Oryza glumaepatula73.730.0 652
LLPS-Orni-1292Oryza nivara73.730.0 652
LLPS-Ori-2013Oryza indica73.730.0 651
LLPS-Phv-1014Phaseolus vulgaris73.510.0 648
LLPS-Art-2760Arabidopsis thaliana73.510.0 647
LLPS-Tra-0098Triticum aestivum73.510.0 650
LLPS-Hov-1223Hordeum vulgare73.510.0 650
LLPS-Sot-0919Solanum tuberosum73.510.0 646
LLPS-Via-1858Vigna angularis73.510.0 647
LLPS-Sol-1650Solanum lycopersicum73.510.0 646
LLPS-Nia-1073Nicotiana attenuata73.290.0 646
LLPS-Zem-0717Zea mays73.070.0 643
LLPS-Abg-0022Absidia glauca73.070.0 652
LLPS-Bro-0545Brassica oleracea73.010.0 647
LLPS-Brr-0087Brassica rapa73.010.0 647
LLPS-Brn-1155Brassica napus73.010.0 647
LLPS-Fud-0800Fukomys damarensis73.00.0 591
LLPS-Sob-0458Sorghum bicolor72.850.0 644
LLPS-Sei-0505Setaria italica72.850.0 644
LLPS-Hea-0419Helianthus annuus72.850.0 635
LLPS-Dac-1429Daucus carota72.410.0 633
LLPS-Vir-0337Vigna radiata72.20.0 637
LLPS-Mua-0215Musa acuminata72.140.0 643
LLPS-Scj-0610Schizosaccharomyces japonicus72.040.0 616
LLPS-Gas-0037Galdieria sulphuraria71.680.0 641
LLPS-Tru-1043Triticum urartu71.610.0 642
LLPS-Scc-0980Schizosaccharomyces cryophilus71.360.0 613
LLPS-Chc-0372Chondrus crispus70.820.0 607
LLPS-Spr-0759Sporisorium reilianum70.440.0 614
LLPS-Scp-0221Schizosaccharomyces pombe70.250.0 608
LLPS-Usm-0861Ustilago maydis70.220.0 613
LLPS-Crn-0677Cryptococcus neoformans70.20.0 600
LLPS-Mel-0033Melampsora laricipopulina69.330.0 614
LLPS-Pytr-0249Pyrenophora triticirepentis69.210.0 598
LLPS-Lem-0404Leptosphaeria maculans69.140.0 581
LLPS-Pyt-0122Pyrenophora teres69.060.0 595
LLPS-Phn-0454Phaeosphaeria nodorum68.680.0 602
LLPS-Asfu-0003Aspergillus fumigatus68.390.0 597
LLPS-Asn-0024Aspergillus nidulans68.160.0 596
LLPS-Nef-0605Neosartorya fischeri68.040.0 540
LLPS-Ved-0904Verticillium dahliae68.010.0 596
LLPS-Tum-0903Tuber melanosporum68.010.0 594
LLPS-Blg-0089Blumeria graminis68.010.0 593
LLPS-Gag-0256Gaeumannomyces graminis68.010.0 594
LLPS-Aso-0378Aspergillus oryzae67.940.0 595
LLPS-Asni-0471Aspergillus niger67.940.0 592
LLPS-Asf-0197Aspergillus flavus67.790.0 589
LLPS-Map-0256Magnaporthe poae67.790.0 591
LLPS-Scs-0066Sclerotinia sclerotiorum67.60.0 566
LLPS-Ast-0167Aspergillus terreus67.184e-174 503
LLPS-Cogr-0457Colletotrichum graminicola67.110.0 597
LLPS-Trv-0551Trichoderma virens67.110.0 594
LLPS-Miv-0202Microbotryum violaceum67.110.0 590
LLPS-Trr-1136Trichoderma reesei67.110.0 593
LLPS-Cog-0247Colletotrichum gloeosporioides67.110.0 596
LLPS-Nec-0642Neurospora crassa67.110.0 572
LLPS-Coo-0853Colletotrichum orbiculare67.110.0 595
LLPS-Mao-0694Magnaporthe oryzae66.890.0 590
LLPS-Chr-0762Chlamydomonas reinhardtii66.670.0 577
LLPS-Beb-0718Beauveria bassiana66.590.0 591
LLPS-Put-0969Puccinia triticina66.520.0 594
LLPS-Fuo-1302Fusarium oxysporum66.450.0 590
LLPS-Pug-0804Puccinia graminis66.450.0 597
LLPS-Fuv-1489Fusarium verticillioides66.450.0 590
LLPS-Fus-0384Fusarium solani66.440.0 587
LLPS-Zyt-0693Zymoseptoria tritici66.370.0 574
LLPS-Orp-0710Oryza punctata65.810.0 574
LLPS-Osl-0049Ostreococcus lucimarinus64.550.0 532
LLPS-Asc-0057Aspergillus clavatus64.290.0 545
LLPS-Yal-1473Yarrowia lipolytica61.568e-176 508
LLPS-Dos-0965Dothistroma septosporum61.240.0 555
LLPS-Cym-0985Cyanidioschyzon merolae48.921e-147 438
LLPS-Kop-0240Komagataella pastoris43.787e-102 318
LLPS-Asg-0667Ashbya gossypii43.469e-107 332
LLPS-Cae-0130Caenorhabditis elegans42.863e-103 322
LLPS-Sac-0112Saccharomyces cerevisiae39.872e-92 295