• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Tag-0643
TUBG1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Tubulin gamma chain
Gene Name: TUBG1
Ensembl Gene: ENSTGUG00000002727.1
Ensembl Protein: ENSTGUP00000002807.1
Organism: Taeniopygia guttata
Taxa ID: 59729
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, OthersPredicted from orthologs(View)

▼ FUNCTION

Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSTGUT00000002836.1ENSTGUP00000002807.1
UniProtH0YWY3, H0YWY3_TAEGU
GeneBankABQF01052756

▼ SEQUENCE

Protein Sequence (FASTA)
1     ADDEHYIPRA  VLLDLEPRVI  HSILNSPYAN  LYNPENIYLS  EHGGGAGNNW  ASGFSQGEKI  60
61    HEDIFDIIDR  EADGSDSLEG  FVLCHSIAGG  TGSGLGSYLL  EKLNDRYPKK  LVETYSVFPN  120
121   QDEMSDVVVQ  PYNSLLTLKR  LTQNADCVVV  LDNTALNRIA  TDRLHIQNPS  FSQINQLVST  180
181   IMSASTTTLR  YPGYMNNDLI  GLIASLIPTP  RLHFLMTGYT  PLTTDQSVAS  VRKTTVLDVM  240
241   RRLLQPKNVM  VSTGRDRQTN  HCYIAILNII  QGEVDPTQVH  KSLQRIRERK  LANFIPWGPA  300
301   SIQVALSRKS  PYLPSAHRVS  GLMMANHTNI  SSLFERTCRQ  YDKLRKREAF  LEQFRKEDIF  360
361   KDNFDELDNS  REIVQQLIDE  YHAATRPDYI  SWGTQEQ  397
Nucleotide CDS Sequence (FASTA)
1     GCGGATGATG  AGCACTACAT  CCCCCGGGCC  GTGCTGCTGG  ACCTGGAGCC  CCGTGTCATC  60
61    CACTCCATCC  TCAACTCCCC  TTACGCCAAC  CTTTACAACC  CAGAAAACAT  CTACCTGTCC  120
121   GAGCATGGAG  GGGGAGCTGG  CAACAACTGG  GCCAGTGGCT  TCTCGCAGGG  AGAAAAGATC  180
181   CATGAAGATA  TTTTTGACAT  AATAGACAGA  GAGGCTGATG  GGAGTGACAG  TTTGGAAGGG  240
241   TTTGTGCTCT  GCCACTCCAT  CGCTGGTGGA  ACAGGCTCTG  GGCTGGGCTC  GTACCTGCTG  300
301   GAGAAGCTGA  ATGACAGGTA  TCCCAAGAAA  CTGGTGGAGA  CCTACTCAGT  GTTCCCAAAC  360
361   CAGGATGAGA  TGAGCGATGT  TGTAGTCCAG  CCGTACAACT  CTCTGCTGAC  TCTGAAGAGG  420
421   CTGACCCAGA  ATGCTGACTG  TGTGGTGGTT  CTGGACAACA  CAGCCTTGAA  TCGGATCGCG  480
481   ACAGACCGGC  TGCACATCCA  GAACCCGTCA  TTCTCACAGA  TCAACCAGCT  GGTGTCCACC  540
541   ATCATGTCTG  CCAGCACCAC  CACGCTCAGG  TATCCCGGCT  ACATGAACAA  TGACCTGATC  600
601   GGGCTGATCG  CCTCGCTGAT  CCCCACGCCC  CGGCTGCACT  TCCTGATGAC  GGGCTACACA  660
661   CCACTCACCA  CCGACCAGTC  GGTGGCCAGT  GTGAGGAAAA  CCACAGTCCT  GGATGTGATG  720
721   AGAAGGTTGC  TGCAGCCTAA  AAACGTGATG  GTGTCCACAG  GGCGAGACAG  GCAGACCAAC  780
781   CACTGCTACA  TTGCCATCCT  CAACATCATC  CAGGGGGAGG  TGGATCCTAC  ACAGGTTCAC  840
841   AAGAGTCTGC  AGCGGATCCG  GGAGAGGAAG  TTGGCCAACT  TCATCCCCTG  GGGCCCTGCC  900
901   AGCATCCAGG  TGGCTTTGTC  CCGCAAGTCC  CCTTACCTGC  CGTCCGCTCA  CCGCGTCAGC  960
961   GGGCTCATGA  TGGCAAACCA  CACCAACATC  TCCTCGCTGT  TTGAGCGGAC  GTGCCGGCAG  1020
1021  TACGACAAGC  TGCGCAAGCG  AGAGGCCTTC  CTGGAGCAGT  TCCGCAAGGA  GGACATTTTC  1080
1081  AAGGACAACT  TCGATGAGCT  GGACAACTCC  CGTGAGATCG  TGCAGCAGCT  GATCGACGAG  1140
1141  TACCACGCAG  CCACACGCCC  TGACTACATC  TCCTGGGGCA  CGCAGGAGCA  G  1191

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Microtubule
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Apical part of cell
Cellular Component
Cell leading edge
Cellular Component
Centriole
Cellular Component
Ciliary basal body
Cellular Component
Condensed nuclear chromosome
Cellular Component
Cytoplasmic microtubule
Cellular Component
Gamma-tubulin complex
Cellular Component
Non-motile cilium
Cellular Component
Pericentriolar material
Cellular Component
Polar microtubule
Cellular Component
Recycling endosome
Molecular Function
GTP binding
Molecular Function
GTPase activity
Molecular Function
Identical protein binding
Biological Process
Cytoplasmic microtubule organization
Biological Process
Meiotic spindle organization
Biological Process
Microtubule nucleation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ora-0381Ornithorhynchus anatinus100.07e-31 125
LLPS-Anp-1399Anas platyrhynchos99.750.0 789
LLPS-Fia-0161Ficedula albicollis99.750.0 789
LLPS-Gaga-0347Gallus gallus99.70.0 648
LLPS-Scf-1156Scleropages formosus99.640.0 540
LLPS-Pes-0676Pelodiscus sinensis99.240.0 786
LLPS-Xet-0488Xenopus tropicalis98.990.0 787
LLPS-Lac-2287Latimeria chalumnae98.740.0 784
LLPS-Eqc-0915Equus caballus98.50.0 646
LLPS-Sus-2740Sus scrofa98.490.0 781
LLPS-Bot-0846Bos taurus98.490.0 780
LLPS-Tut-0954Tursiops truncatus98.490.0 780
LLPS-Asm-0993Astyanax mexicanus98.390.0 522
LLPS-Cea-1755Cercocebus atys98.240.0 780
LLPS-Chs-0849Chlorocebus sabaeus98.240.0 780
LLPS-Paa-0651Papio anubis98.240.0 780
LLPS-Mal-0556Mandrillus leucophaeus98.240.0 780
LLPS-Myl-2128Myotis lucifugus98.240.0 773
LLPS-Man-0538Macaca nemestrina98.240.0 780
LLPS-Hos-1511Homo sapiens98.240.0 780
LLPS-Pat-0067Pan troglodytes98.240.0 780
LLPS-Otg-1161Otolemur garnettii98.240.0 780
LLPS-Leo-2832Lepisosteus oculatus97.980.0 778
LLPS-Icp-0759Ictalurus punctatus97.980.0 778
LLPS-Dar-1612Danio rerio97.980.0 779
LLPS-Fec-0962Felis catus97.980.0 778
LLPS-Caf-1424Canis familiaris97.980.0 778
LLPS-Aim-2104Ailuropoda melanoleuca97.490.0 773
LLPS-Mum-1852Mus musculus97.480.0 774
LLPS-Dio-0051Dipodomys ordii97.480.0 774
LLPS-Ova-0913Ovis aries97.480.0 775
LLPS-Ran-0496Rattus norvegicus97.480.0 774
LLPS-Orc-0078Oryctolagus cuniculus97.480.0 776
LLPS-Ict-0551Ictidomys tridecemlineatus97.480.0 774
LLPS-Orl-0832Oryzias latipes97.230.0 771
LLPS-Gaa-1065Gasterosteus aculeatus97.230.0 770
LLPS-Mup-0393Mustela putorius furo97.230.0 773
LLPS-Loa-0276Loxodonta africana97.230.0 773
LLPS-Cap-1771Cavia porcellus97.230.0 771
LLPS-Urm-0893Ursus maritimus96.980.0 772
LLPS-Scm-2656Scophthalmus maximus96.730.0 768
LLPS-Mea-0857Mesocricetus auratus96.632e-107 325
LLPS-Xim-1680Xiphophorus maculatus96.470.0 765
LLPS-Maf-0987Macaca fascicularis95.970.0 764
LLPS-Tar-2008Takifugu rubripes95.970.0 762
LLPS-Poa-2281Pongo abelii95.970.0 764
LLPS-Ten-0091Tetraodon nigroviridis95.720.0 760
LLPS-Mod-0311Monodelphis domestica95.610.0 773
LLPS-Fud-0383Fukomys damarensis95.33e-85 266
LLPS-Mam-0431Macaca mulatta95.120.0 770
LLPS-Nol-1299Nomascus leucogenys95.120.0 771
LLPS-Cas-0803Carlito syrichta94.870.0 764
LLPS-Sah-0982Sarcophilus harrisii94.650.0 765
LLPS-Anc-0461Anolis carolinensis94.460.0 747
LLPS-Pof-0468Poecilia formosa94.310.0 751
LLPS-Caj-0526Callithrix jacchus93.840.0 757
LLPS-Rhb-1017Rhinopithecus bieti93.840.0 757
LLPS-Aon-0731Aotus nancymaae93.170.0 754
LLPS-Orn-3626Oreochromis niloticus92.960.0 758
LLPS-Gog-0270Gorilla gorilla92.480.0 755
LLPS-Pap-0259Pan paniscus92.480.0 755
LLPS-Cis-0841Ciona savignyi82.870.0 682
LLPS-Cii-0525Ciona intestinalis82.530.0 673
LLPS-Drm-0146Drosophila melanogaster77.750.0 629
LLPS-Sem-0023Selaginella moellendorffii75.750.0 600
LLPS-Php-0481Physcomitrella patens75.250.0 599
LLPS-Amt-0123Amborella trichopoda74.690.0 595
LLPS-Orbr-0545Oryza brachyantha74.440.0 593
LLPS-Orb-1340Oryza barthii74.370.0 590
LLPS-Ori-2013Oryza indica74.190.0 591
LLPS-Orni-1292Oryza nivara74.190.0 591
LLPS-Lep-1121Leersia perrieri74.190.0 590
LLPS-Orgl-0228Oryza glumaepatula74.190.0 591
LLPS-Brd-1944Brachypodium distachyon74.190.0 590
LLPS-Ors-0312Oryza sativa74.190.0 591
LLPS-Orm-0449Oryza meridionalis74.190.0 592
LLPS-Orr-0092Oryza rufipogon74.190.0 591
LLPS-Org-0740Oryza glaberrima74.190.0 591
LLPS-Thc-0023Theobroma cacao74.00.0 583
LLPS-Hov-1223Hordeum vulgare73.930.0 590
LLPS-Tra-0098Triticum aestivum73.930.0 590
LLPS-Tru-1043Triticum urartu73.930.0 591
LLPS-Glm-2540Glycine max73.680.0 585
LLPS-Arl-2592Arabidopsis lyrata73.680.0 586
LLPS-Cus-0741Cucumis sativus73.680.0 586
LLPS-Pot-2099Populus trichocarpa73.680.0 587
LLPS-Viv-0719Vitis vinifera73.680.0 586
LLPS-Gor-2337Gossypium raimondii73.680.0 587
LLPS-Mae-0092Manihot esculenta73.680.0 585
LLPS-Mua-0215Musa acuminata73.50.0 590
LLPS-Via-1858Vigna angularis73.430.0 585
LLPS-Met-0533Medicago truncatula73.430.0 584
LLPS-Art-2760Arabidopsis thaliana73.430.0 585
LLPS-Phv-1014Phaseolus vulgaris73.430.0 586
LLPS-Coc-1258Corchorus capsularis73.430.0 584
LLPS-Zem-0717Zea mays73.430.0 584
LLPS-Prp-0253Prunus persica73.370.0 576
LLPS-Sei-0505Setaria italica73.180.0 584
LLPS-Sob-0458Sorghum bicolor73.180.0 584
LLPS-Sol-1650Solanum lycopersicum72.680.0 581
LLPS-Hea-0419Helianthus annuus72.680.0 573
LLPS-Abg-0022Absidia glauca72.680.0 589
LLPS-Sot-0919Solanum tuberosum72.680.0 581
LLPS-Brn-1155Brassica napus72.610.0 583
LLPS-Brr-0087Brassica rapa72.610.0 583
LLPS-Bro-0545Brassica oleracea72.610.0 583
LLPS-Nia-1073Nicotiana attenuata72.430.0 581
LLPS-Scj-0610Schizosaccharomyces japonicus72.260.0 556
LLPS-Dac-1429Daucus carota72.180.0 570
LLPS-Vir-0337Vigna radiata71.950.0 575
LLPS-Gas-0037Galdieria sulphuraria71.860.0 585
LLPS-Scc-0980Schizosaccharomyces cryophilus71.760.0 555
LLPS-Mel-0033Melampsora laricipopulina71.460.0 571
LLPS-Spr-0759Sporisorium reilianum71.320.0 564
LLPS-Usm-0861Ustilago maydis71.070.0 564
LLPS-Crn-0677Cryptococcus neoformans70.280.0 551
LLPS-Put-0969Puccinia triticina69.80.0 560
LLPS-Chc-0372Chondrus crispus69.70.0 548
LLPS-Pug-0804Puccinia graminis69.70.0 561
LLPS-Scp-0221Schizosaccharomyces pombe69.470.0 544
LLPS-Pyt-0122Pyrenophora teres68.960.0 544
LLPS-Pytr-0249Pyrenophora triticirepentis68.960.0 546
LLPS-Lem-0404Leptosphaeria maculans68.950.0 529
LLPS-Tum-0903Tuber melanosporum68.70.0 548
LLPS-Phn-0454Phaeosphaeria nodorum67.940.0 541
LLPS-Miv-0202Microbotryum violaceum67.930.0 545
LLPS-Asni-0471Aspergillus niger67.350.0 536
LLPS-Map-0256Magnaporthe poae67.180.0 532
LLPS-Blg-0089Blumeria graminis67.180.0 533
LLPS-Ved-0904Verticillium dahliae67.180.0 536
LLPS-Asn-0024Aspergillus nidulans67.090.0 535
LLPS-Nef-0605Neosartorya fischeri67.090.0 536
LLPS-Asfu-0003Aspergillus fumigatus67.090.0 535
LLPS-Gag-0256Gaeumannomyces graminis66.920.0 530
LLPS-Coo-0853Colletotrichum orbiculare66.920.0 538
LLPS-Cog-0247Colletotrichum gloeosporioides66.920.0 540
LLPS-Cogr-0457Colletotrichum graminicola66.920.0 541
LLPS-Scs-0066Sclerotinia sclerotiorum66.670.0 535
LLPS-Mao-0694Magnaporthe oryzae66.670.0 533
LLPS-Aso-0378Aspergillus oryzae66.580.0 533
LLPS-Asf-0197Aspergillus flavus66.580.0 533
LLPS-Ast-0167Aspergillus terreus66.580.0 531
LLPS-Fuv-1489Fusarium verticillioides66.410.0 532
LLPS-Trr-1136Trichoderma reesei66.410.0 534
LLPS-Trv-0551Trichoderma virens66.410.0 533
LLPS-Fuo-1302Fusarium oxysporum66.410.0 532
LLPS-Zyt-0693Zymoseptoria tritici66.330.0 521
LLPS-Nec-0642Neurospora crassa66.164e-178 512
LLPS-Fus-0384Fusarium solani66.160.0 530
LLPS-Chr-0762Chlamydomonas reinhardtii65.60.0 519
LLPS-Beb-0718Beauveria bassiana65.580.0 530
LLPS-Orp-0710Oryza punctata65.221e-176 508
LLPS-Osl-0049Ostreococcus lucimarinus64.495e-168 486
LLPS-Asc-0057Aspergillus clavatus63.160.0 527
LLPS-Yal-1473Yarrowia lipolytica61.581e-154 451
LLPS-Dos-0965Dothistroma septosporum60.321e-172 499
LLPS-Cym-0985Cyanidioschyzon merolae48.347e-129 388
LLPS-Cae-0130Caenorhabditis elegans43.728e-101 313
LLPS-Kop-0240Komagataella pastoris43.432e-90 286
LLPS-Asg-0667Ashbya gossypii42.751e-93 296
LLPS-Sac-0112Saccharomyces cerevisiae39.695e-82 266