LLPS-Mum-3335
Cstb
▼ OVERVIEW
Status: | Unreviewed |
Protein Name: | Cystatin-B; Stefin-B |
Gene Name: | Cstb, Cst6, Stfb |
Ensembl Gene: | ENSMUSG00000005054.7 |
Ensembl Protein: | ENSMUSP00000005185.6 |
Organism: | Mus musculus |
Taxa ID: | 10090 |
LLPS Type: | Others |
▼ Classification
Condensates:
Condensate | Evidence | Orthologs |
---|---|---|
Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
This is an intracellular thiol proteinase inhibitor. |
▼ CROSS REFERENCE
Database | Nucleotide ID | Protein ID |
---|---|---|
Ensembl | ENSMUST00000005185.7 | ENSMUSP00000005185.6 |
UniProt | Q62426, CYTB_MOUSE, Q3UAW2 | |
GeneBank | BC056170, AK151205, U59807, AK002403 | BAE30202.1, AAC52851.1, BAB22074.1, AAH56170.1 |
RefSeq | NM_007793.3 | NP_031819.1 |
Entrez | 13014 |
▼ SEQUENCE
Protein Sequence (FASTA) |
---|
1 MMCGAPSATM PATAETQEVA DQVKSQLESK ENQKFDVFKA ISFKRQIVAG TNLFIKVDVG 60 61 GDKCVHLRVF QPLPHENKPL TLSSYQTNKE RHDELSYF 98 |
Nucleotide CDS Sequence (FASTA) |
1 ATGATGTGTG GCGCGCCATC TGCCACAATG CCAGCCACGG CCGAGACGCA GGAGGTCGCC 60 61 GACCAGGTGA AGTCCCAGCT TGAATCGAAA GAAAATCAGA AGTTTGATGT CTTTAAAGCC 120 121 ATATCCTTCA AGAGACAGAT AGTGGCTGGC ACCAACCTCT TCATCAAGGT TGATGTTGGT 180 181 GGAGATAAAT GCGTGCACTT GAGGGTGTTT CAACCCCTCC CCCATGAAAA CAAGCCTTTG 240 241 ACCCTGTCTT CCTATCAGAC CAACAAAGAA AGGCACGATG AGCTCTCCTA CTTCTGA 297 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Collagen-containing extracellular matrix | |
Cellular Component | Cytoplasm | |
Cellular Component | Cytosol | |
Cellular Component | Extracellular space | |
Cellular Component | Nucleolus | |
Cellular Component | Nucleus | |
Molecular Function | Cysteine-type endopeptidase inhibitor activity | |
Molecular Function | Endopeptidase inhibitor activity | |
Molecular Function | Protease binding | |
Biological Process | Adult locomotory behavior | |
Biological Process | Negative regulation of peptidase activity | |
Biological Process | Negative regulation of proteolysis |
▼ ANNOTATION
Mutation | ||||
CGAP |
Physicochemical | ||||
Compute pI/Mw | AAindex |
Function | ||||
CGDB | CellMarker |
Localization | ||||
COMPARTMENTS |
Expression | ||||
ArrayExpress | GXD | TISSUES |
Element | ||||
miRWalk | RAID | microRNA.org |
▼ ORTHOLOGY
DrLLPS ID | Organism | Identity | E-value | Score |
---|---|---|---|---|
LLPS-Ran-4824 | Rattus norvegicus | 85.71 | 4e-60 | 185 |
LLPS-Mea-0638 | Mesocricetus auratus | 79.38 | 1e-52 | 166 |
LLPS-Pat-4316 | Pan troglodytes | 78.57 | 1e-52 | 166 |
LLPS-Hos-0857 | Homo sapiens | 78.57 | 3e-52 | 165 |
LLPS-Poa-1546 | Pongo abelii | 78.57 | 3e-52 | 165 |
LLPS-Aon-3455 | Aotus nancymaae | 78.57 | 3e-52 | 166 |
LLPS-Rhb-2596 | Rhinopithecus bieti | 77.55 | 3e-51 | 163 |
LLPS-Mam-1050 | Macaca mulatta | 77.55 | 3e-51 | 163 |
LLPS-Maf-3638 | Macaca fascicularis | 77.55 | 3e-51 | 163 |
LLPS-Paa-2553 | Papio anubis | 77.55 | 3e-51 | 163 |
LLPS-Eqc-2079 | Equus caballus | 76.53 | 3e-51 | 163 |
LLPS-Chs-3447 | Chlorocebus sabaeus | 76.53 | 8e-51 | 162 |
LLPS-Cea-3404 | Cercocebus atys | 76.53 | 7e-51 | 162 |
LLPS-Sus-4704 | Sus scrofa | 76.53 | 9e-50 | 159 |
LLPS-Caj-3239 | Callithrix jacchus | 76.53 | 3e-51 | 162 |
LLPS-Man-2593 | Macaca nemestrina | 75.51 | 1e-49 | 159 |
LLPS-Loa-2472 | Loxodonta africana | 75.51 | 4e-50 | 160 |
LLPS-Otg-3441 | Otolemur garnettii | 75.51 | 9e-50 | 159 |
LLPS-Ict-0735 | Ictidomys tridecemlineatus | 75.0 | 1e-36 | 125 |
LLPS-Mal-0034 | Mandrillus leucophaeus | 74.49 | 3e-49 | 158 |
LLPS-Cas-1500 | Carlito syrichta | 73.47 | 5e-48 | 154 |
LLPS-Orc-2412 | Oryctolagus cuniculus | 72.73 | 1e-35 | 122 |
LLPS-Bot-1979 | Bos taurus | 71.43 | 4e-45 | 149 |
LLPS-Cap-2487 | Cavia porcellus | 70.41 | 3e-48 | 155 |
LLPS-Fec-2201 | Felis catus | 70.33 | 1e-40 | 137 |
LLPS-Sah-3921 | Sarcophilus harrisii | 69.39 | 8e-46 | 149 |
LLPS-Caf-4022 | Canis familiaris | 68.83 | 2e-33 | 117 |
LLPS-Aim-0136 | Ailuropoda melanoleuca | 68.83 | 2e-33 | 117 |
LLPS-Dio-2264 | Dipodomys ordii | 68.42 | 3e-33 | 116 |
LLPS-Mup-3651 | Mustela putorius furo | 67.53 | 9e-33 | 115 |
LLPS-Mod-4316 | Monodelphis domestica | 67.35 | 8e-42 | 140 |
LLPS-Tut-0339 | Tursiops truncatus | 66.33 | 2e-41 | 138 |
LLPS-Nol-3205 | Nomascus leucogenys | 65.98 | 3e-37 | 127 |
LLPS-Ora-3526 | Ornithorhynchus anatinus | 65.59 | 4e-35 | 127 |
LLPS-Pap-4561 | Pan paniscus | 64.95 | 4e-37 | 127 |
LLPS-Fia-0385 | Ficedula albicollis | 64.47 | 3e-29 | 107 |
LLPS-Myl-4467 | Myotis lucifugus | 64.29 | 1e-40 | 136 |
LLPS-Gog-2917 | Gorilla gorilla | 63.92 | 2e-36 | 125 |
LLPS-Ova-3546 | Ovis aries | 63.27 | 8e-40 | 134 |
LLPS-Tag-2223 | Taeniopygia guttata | 63.04 | 5e-37 | 126 |
LLPS-Meg-1980 | Meleagris gallopavo | 62.24 | 3e-41 | 137 |
LLPS-Gaga-3792 | Gallus gallus | 62.24 | 5e-41 | 137 |
LLPS-Fud-4273 | Fukomys damarensis | 61.84 | 2e-27 | 101 |
LLPS-Pes-3494 | Pelodiscus sinensis | 60.2 | 3e-39 | 132 |
LLPS-Anc-2234 | Anolis carolinensis | 59.18 | 1e-37 | 129 |
LLPS-Leo-2095 | Lepisosteus oculatus | 53.06 | 3e-32 | 114 |
LLPS-Dar-0419 | Danio rerio | 50.0 | 2e-28 | 104 |
LLPS-Icp-2039 | Ictalurus punctatus | 50.0 | 8e-28 | 104 |
LLPS-Asm-2864 | Astyanax mexicanus | 46.94 | 2e-27 | 102 |
LLPS-Scf-0432 | Scleropages formosus | 46.84 | 4e-18 | 79.7 |
LLPS-Orl-1897 | Oryzias latipes | 45.36 | 7e-23 | 90.5 |
LLPS-Gaa-2164 | Gasterosteus aculeatus | 44.33 | 8e-22 | 87.8 |
LLPS-Pof-3622 | Poecilia formosa | 43.88 | 7e-25 | 95.5 |
LLPS-Xim-0505 | Xiphophorus maculatus | 43.43 | 2e-22 | 89.7 |
LLPS-Orn-3594 | Oreochromis niloticus | 41.24 | 2e-19 | 81.6 |
LLPS-Ten-1468 | Tetraodon nigroviridis | 40.82 | 5e-19 | 80.5 |
LLPS-Tar-2795 | Takifugu rubripes | 40.21 | 1e-20 | 84.7 |
LLPS-Scm-2839 | Scophthalmus maximus | 39.18 | 8e-18 | 78.2 |
LLPS-Xet-2527 | Xenopus tropicalis | 36.08 | 5e-15 | 70.1 |