• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mod-2336

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Lysozyme
Ensembl Gene: ENSMODG00000025143.2
Ensembl Protein: ENSMODP00000025484.2
Organism: Monodelphis domestica
Taxa ID: 13616
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, P-bodyPredicted from orthologs(View)

▼ FUNCTION

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSMODT00000025935.2ENSMODP00000025484.2
UniProtF7F6F0, F7F6F0_MONDO

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRFQRNILHS  SFLSSGGGAF  QQQEELKREV  KYWSSAQAQE  LDCFDFSGIM  KVLILLGLVF  60
61    LPMLAHGKVY  ERCELARILK  QNGMDGYRGI  SLANWVCLAK  WESNYNTRVT  NYNSRDRSTD  120
121   YGIFQINSRY  WCNDGKTPRA  VNACGISCRD  LLTDNISKAI  TCAKRVVRDP  SGIRAWVAWR  180
181   NRCQGKNLSS  YIQGCRL  197
Nucleotide CDS Sequence (FASTA)
1     ATGAGATTTC  AGAGAAACAT  TCTTCACTCT  TCCTTTCTCA  GTTCAGGAGG  TGGAGCCTTC  60
61    CAACAGCAGG  AAGAACTTAA  GAGAGAAGTT  AAATACTGGA  GCTCAGCTCA  GGCTCAGGAG  120
121   TTAGACTGCT  TTGACTTCTC  AGGCATCATG  AAGGTCCTGA  TTCTTTTGGG  TCTTGTCTTC  180
181   CTCCCCATGC  TAGCTCATGG  CAAGGTCTAC  GAAAGATGTG  AATTGGCAAG  AATCCTGAAG  240
241   CAAAATGGGA  TGGATGGCTA  CAGAGGTATC  AGCCTGGCCA  ACTGGGTGTG  CTTGGCAAAA  300
301   TGGGAAAGCA  ATTATAACAC  ACGAGTCACA  AACTACAACT  CTAGAGATCG  AAGCACAGAT  360
361   TATGGAATAT  TTCAGATCAA  CAGTCGCTAC  TGGTGCAATG  ATGGGAAGAC  CCCTAGAGCT  420
421   GTGAATGCGT  GTGGCATCTC  ATGTAGAGAT  CTTTTAACAG  ATAATATCAG  CAAAGCTATA  480
481   ACCTGTGCAA  AGAGGGTTGT  CCGTGATCCC  AGTGGCATTC  GGGCATGGGT  GGCATGGAGA  540
541   AACCGTTGCC  AAGGAAAGAA  TCTTTCCTCT  TATATCCAAG  GTTGCCGTCT  TTAG  594

▼ KEYWORD

ID
Family
Antimicrobial
Bacteriolytic enzyme
Complete proteome
Disulfide bond
Glycosidase
Hydrolase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Lysozyme activity
Biological Process
Cytolysis
Biological Process
Defense response to Gram-negative bacterium
Biological Process
Defense response to Gram-positive bacterium
Biological Process
Metabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Loa-1808Loxodonta africana78.463e-73 225
LLPS-Nol-0807Nomascus leucogenys77.43e-79 240
LLPS-Pap-0434Pan paniscus76.035e-79 239
LLPS-Pat-1836Pan troglodytes76.035e-79 239
LLPS-Hos-0111Homo sapiens76.035e-79 239
LLPS-Otg-2633Otolemur garnettii76.032e-72 223
LLPS-Man-0275Macaca nemestrina76.02e-51 168
LLPS-Poa-0211Pongo abelii75.347e-78 236
LLPS-Ict-3525Ictidomys tridecemlineatus75.343e-73 224
LLPS-Gog-0589Gorilla gorilla75.347e-79 239
LLPS-Ora-1578Ornithorhynchus anatinus73.973e-78 237
LLPS-Ten-3435Tetraodon nigroviridis73.853e-63 200
LLPS-Cap-2564Cavia porcellus73.291e-72 223
LLPS-Mam-1901Macaca mulatta73.296e-77 234
LLPS-Chs-0824Chlorocebus sabaeus73.298e-77 234
LLPS-Mum-3821Mus musculus73.294e-70 216
LLPS-Maf-2614Macaca fascicularis73.296e-77 234
LLPS-Fud-3180Fukomys damarensis73.119e-64 200
LLPS-Paa-1025Papio anubis72.62e-76 233
LLPS-Mal-0328Mandrillus leucophaeus72.62e-76 233
LLPS-Aon-4398Aotus nancymaae72.61e-76 233
LLPS-Cea-0211Cercocebus atys72.62e-76 233
LLPS-Orc-3976Oryctolagus cuniculus71.923e-72 222
LLPS-Myl-1402Myotis lucifugus71.927e-70 216
LLPS-Caj-1787Callithrix jacchus71.922e-68 213
LLPS-Dio-2946Dipodomys ordii71.621e-76 233
LLPS-Sus-0797Sus scrofa71.214e-66 206
LLPS-Eqc-1535Equus caballus70.958e-71 219
LLPS-Ova-1860Ovis aries70.781e-79 242
LLPS-Ran-2999Rattus norvegicus70.778e-64 201
LLPS-Tut-0992Tursiops truncatus70.556e-70 216
LLPS-Rhb-2121Rhinopithecus bieti69.181e-73 226
LLPS-Aim-3134Ailuropoda melanoleuca69.181e-66 208
LLPS-Urm-2187Ursus maritimus68.676e-67 210
LLPS-Mup-1770Mustela putorius furo68.677e-68 212
LLPS-Caf-3730Canis familiaris68.494e-67 209
LLPS-Bot-4160Bos taurus68.492e-67 210
LLPS-Scf-1311Scleropages formosus67.196e-54 175
LLPS-Cas-0031Carlito syrichta67.128e-65 203
LLPS-Xim-1813Xiphophorus maculatus65.913e-55 179
LLPS-Fec-4248Felis catus65.755e-66 206
LLPS-Tar-0246Takifugu rubripes65.153e-55 179
LLPS-Pof-0938Poecilia formosa64.869e-60 190
LLPS-Mea-2800Mesocricetus auratus64.389e-61 193
LLPS-Orn-0834Oreochromis niloticus64.292e-56 181
LLPS-Pes-2828Pelodiscus sinensis64.196e-61 193
LLPS-Sah-1437Sarcophilus harrisii64.196e-70 216
LLPS-Icp-0001Ictalurus punctatus62.61e-49 164
LLPS-Gaa-3546Gasterosteus aculeatus61.743e-60 192
LLPS-Asm-1202Astyanax mexicanus60.165e-46 155
LLPS-Anp-2294Anas platyrhynchos60.143e-59 189
LLPS-Gaga-0000Gallus gallus57.437e-58 186
LLPS-Meg-0574Meleagris gallopavo56.765e-56 181
LLPS-Orl-2754Oryzias latipes56.42e-57 185
LLPS-Xet-3425Xenopus tropicalis54.052e-50 166
LLPS-Anc-3811Anolis carolinensis53.472e-43 149
LLPS-Lac-0870Latimeria chalumnae53.03e-33 120
LLPS-Fia-1407Ficedula albicollis52.673e-46 155
LLPS-Ere-0001Erinaceus europaeus42.958e-37 131
LLPS-Dar-3757Danio rerio39.315e-32 119
LLPS-Drm-1113Drosophila melanogaster38.282e-2088.6