• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Miv-0591
MVLG_01128

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: AP-2 complex subunit alpha
Gene Name: MVLG_01128
Ensembl Gene: MVLG_01128
Ensembl Protein: MVLG_01128T0
Organism: Microbotryum violaceum
Taxa ID: 683840
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblMVLG_01128T0MVLG_01128T0
UniProtU5H166, U5H166_USTV1
GeneBankGL541648, AEIJ01000097, KDE08669.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLRVPNMNKD  EMRGLTQYIA  DLRACRVREL  EEKRINKEMA  HIRQKFKEGN  LDGRQKKKYI  60
61    SKIIFTSILG  YPVDVGHMEA  VNLISSTKYS  EKQIGYLALT  LLMHENSDLV  RLIVNSIRKD  120
121   LDGLDETVNC  LALHAIANIG  GAEMAEALAS  DVHRLLISPT  SRSFVKKKAA  LTLLRLYRKH  180
181   PGVIPSAEWA  SRIVSIMDDQ  DLGVALAVAS  LVLTLAQDNL  SAYTVAYQKA  VERLAKIVLE  240
241   NEYPSDYLYY  KVPIPWLQVK  LLRLLQYYPP  SEDANLRLTL  HKVLERTLKN  SQDTPKNPQH  300
301   NNALNAVLFE  AINLAIHLDT  ESSIVHSAAL  LLGRFISAKE  TNVRYLGLDT  MTHLAARSES  360
361   LDAIKVHQNV  IIQSLRDKDI  SVRRRGLDLL  YSMCDTSNSK  VIVSELLKYL  PIADYTLREE  420
421   MVLKIAILTE  KFAVEYEWYV  DTILKLMSTA  GDHVGDEVWY  RIVQIVTNTE  ELQEYAAQKV  480
481   CHHLSLPNCH  ENILKVGAYI  LGEYGHLIAD  EEGGSPIEQF  QLVTSRANFA  SASTKALLLT  540
541   TYFKWLNLFP  EIYEQIVNLF  ERYSRVLDAE  LQQRACEYLV  IAKQPDDELL  QVVADEMPPY  600
601   PERESALVSR  LLKKHGDTGD  KRTWHIGGKD  VNRGQDAERY  KGFGRRKMNS  TADATGAAPI  660
661   DATTVGRSKV  IPEVDTTDVM  SSLAGLDLSS  STVERGESSL  APSPLAPALS  PAAGEASLPL  720
721   LGAATSSTAT  TPTTSRKTSL  PLTHGSEKWL  ARLLYNPDGV  LYEDTQLQIG  VKTEYHGHQG  780
781   RIAIFFGNKL  SVALESLTAT  FDVEDEDALE  IKLPSIVPSH  LSASTQVQQL  VLVEGKSIFS  840
841   TPPLLRISYL  AGSHQELVLR  LPAFLTKFIE  PVQLSSDAFF  ERWKQIGGAP  REQQKIFPIV  900
901   ILEGGRVDVA  KQRKVVGGIR  MGLLNGVDPN  PNNLVAAGVL  HMSSVGKVGC  LLRVEPNPER  960
961   KLCRLTVRST  NEQVSTEMLR  LLVGALAAK  989
Nucleotide CDS Sequence (FASTA)
1     ATGTTACGAG  TACCCAACAT  GAACAAGGAT  GAGATGAGGG  GCCTGACCCA  GTACATCGCC  60
61    GACCTCAGGG  CATGTCGCGT  CCGGGAACTC  GAGGAGAAGC  GCATCAACAA  GGAGATGGCC  120
121   CATATTCGTC  AAAAGTTCAA  GGAGGGCAAC  TTGGATGGAA  GGCAAAAGAA  AAAGTACATC  180
181   AGCAAGATCA  TCTTCACCTC  CATCCTCGGT  TACCCCGTCG  ATGTCGGCCA  CATGGAAGCT  240
241   GTAAACCTCA  TCTCGTCGAC  CAAGTACTCG  GAAAAGCAGA  TCGGGTACCT  CGCTCTGACC  300
301   TTGCTCATGC  ACGAAAACTC  GGACCTCGTA  CGGCTGATCG  TCAACTCGAT  CCGGAAAGAC  360
361   CTCGATGGCT  TGGACGAGAC  CGTCAACTGT  CTCGCACTTC  ACGCCATCGC  CAACATTGGT  420
421   GGTGCAGAAA  TGGCCGAGGC  TTTGGCGAGC  GACGTACACC  GTCTCTTGAT  CTCGCCAACA  480
481   TCACGAAGCT  TTGTCAAGAA  AAAGGCAGCG  CTGACCTTGC  TACGACTGTA  CCGCAAGCAC  540
541   CCTGGAGTGA  TCCCTTCCGC  CGAATGGGCC  TCCCGCATCG  TTTCCATCAT  GGACGATCAA  600
601   GACCTGGGCG  TTGCACTCGC  TGTGGCTTCG  CTCGTCCTGA  CCCTGGCTCA  AGACAACCTC  660
661   AGTGCCTACA  CAGTCGCATA  CCAAAAAGCC  GTTGAACGGC  TAGCCAAGAT  CGTTTTGGAG  720
721   AACGAGTACC  CCTCCGACTA  CCTCTACTAC  AAGGTGCCCA  TCCCGTGGCT  TCAAGTCAAG  780
781   CTCCTCCGAC  TGCTCCAGTA  TTACCCCCCA  TCCGAAGACG  CCAATCTCCG  CCTGACTTTG  840
841   CACAAGGTCC  TCGAGCGCAC  TCTCAAGAAC  TCCCAAGACA  CGCCCAAGAA  CCCCCAGCAT  900
901   AACAACGCGC  TCAATGCCGT  TCTCTTCGAG  GCCATCAACC  TCGCCATTCA  TCTGGACACC  960
961   GAATCCTCCA  TCGTGCACTC  GGCCGCACTC  TTGCTGGGCC  GATTCATCTC  GGCCAAGGAG  1020
1021  ACGAATGTGA  GGTACTTGGG  ACTGGACACG  ATGACCCATT  TGGCTGCACG  TTCCGAATCC  1080
1081  TTGGACGCAA  TCAAGGTCCA  CCAAAACGTC  ATCATTCAAT  CGCTTCGAGA  CAAGGACATC  1140
1141  TCGGTCCGTA  GGCGAGGCCT  CGACCTCCTC  TACTCGATGT  GCGACACCTC  CAATTCGAAA  1200
1201  GTCATCGTCA  GCGAGCTGTT  GAAATACCTC  CCCATCGCGG  ACTACACCTT  GAGGGAAGAG  1260
1261  ATGGTGCTCA  AGATCGCCAT  CTTGACCGAA  AAGTTCGCGG  TCGAGTACGA  GTGGTACGTC  1320
1321  GATACGATCC  TCAAGTTGAT  GAGCACCGCC  GGCGACCATG  TCGGCGACGA  GGTTTGGTAC  1380
1381  CGGATCGTGC  AAATCGTCAC  CAACACCGAG  GAGCTGCAAG  AGTATGCCGC  CCAAAAAGTG  1440
1441  TGCCATCACC  TGAGCCTGCC  CAATTGCCAC  GAAAACATCC  TCAAGGTCGG  CGCATACATC  1500
1501  CTTGGAGAAT  ATGGGCATCT  CATCGCGGAT  GAAGAGGGTG  GTTCCCCGAT  CGAGCAATTC  1560
1561  CAACTCGTCA  CCTCGCGCGC  CAACTTCGCC  TCGGCATCGA  CCAAAGCTCT  TCTCTTGACG  1620
1621  ACCTACTTCA  AATGGCTCAA  CCTGTTCCCC  GAGATCTATG  AGCAGATCGT  GAACCTGTTT  1680
1681  GAACGGTATT  CGCGTGTCCT  CGACGCCGAG  TTGCAGCAGC  GCGCTTGCGA  GTATCTCGTC  1740
1741  ATTGCGAAAC  AGCCGGATGA  TGAATTGTTG  CAGGTCGTGG  CTGATGAGAT  GCCGCCTTAT  1800
1801  CCTGAGCGGG  AAAGTGCGCT  GGTGAGTCGA  TTACTGAAGA  AGCACGGCGA  TACCGGCGAC  1860
1861  AAGCGCACAT  GGCACATCGG  CGGCAAGGAC  GTCAACCGAG  GCCAGGATGC  CGAGCGATAC  1920
1921  AAGGGTTTTG  GGCGACGGAA  GATGAATTCC  ACCGCGGACG  CGACGGGCGC  AGCACCCATC  1980
1981  GATGCGACTA  CAGTTGGGAG  GTCGAAGGTC  ATTCCCGAAG  TCGACACAAC  CGATGTCATG  2040
2041  TCCTCACTTG  CTGGGCTGGA  CCTCTCGTCA  TCGACAGTGG  AGAGGGGCGA  AAGTTCATTG  2100
2101  GCCCCTTCTC  CTCTCGCACC  TGCACTTTCA  CCTGCGGCCG  GCGAAGCTTC  ACTCCCCTTG  2160
2161  CTCGGTGCCG  CTACAAGTAG  TACAGCCACC  ACACCGACAA  CATCTCGCAA  GACGTCCCTG  2220
2221  CCGCTCACGC  ACGGGTCCGA  GAAATGGCTA  GCTCGATTGC  TCTACAACCC  CGACGGCGTC  2280
2281  TTGTACGAGG  ATACGCAGCT  GCAGATCGGC  GTCAAGACCG  AGTACCATGG  TCATCAAGGT  2340
2341  CGCATCGCCA  TCTTCTTTGG  CAACAAGCTT  TCGGTCGCGC  TCGAGTCCTT  GACGGCCACC  2400
2401  TTTGACGTCG  AGGACGAAGA  TGCCCTCGAG  ATCAAGCTCC  CTTCGATCGT  ACCATCCCAT  2460
2461  CTTTCCGCCT  CAACCCAAGT  CCAACAACTC  GTCCTAGTCG  AAGGTAAAAG  CATCTTTTCC  2520
2521  ACACCTCCCC  TTTTGCGCAT  CTCCTATCTA  GCAGGCTCGC  ACCAAGAACT  CGTCCTGCGT  2580
2581  CTACCCGCGT  TCCTCACCAA  ATTCATCGAA  CCCGTCCAAC  TCTCCTCGGA  CGCCTTCTTC  2640
2641  GAACGTTGGA  AGCAGATCGG  TGGCGCACCG  AGGGAACAAC  AAAAAATCTT  TCCGATCGTA  2700
2701  ATCCTCGAAG  GGGGCCGAGT  GGACGTGGCT  AAGCAGCGAA  AGGTCGTGGG  TGGGATTCGG  2760
2761  ATGGGTCTCT  TGAATGGCGT  CGATCCGAAC  CCGAATAACC  TGGTTGCGGC  GGGGGTGTTG  2820
2821  CATATGTCGT  CGGTGGGTAA  GGTCGGGTGC  TTGTTGAGGG  TCGAACCTAA  TCCGGAACGA  2880
2881  AAATTGTGCC  GCTTGACCGT  CAGGAGCACG  AATGAGCAAG  TCTCGACCGA  GATGCTTCGG  2940
2941  TTGCTCGTCG  GTGCTCTCGC  CGCCAAA  2967

▼ KEYWORD

ID
Family
Coated pit
Complete proteome
Endocytosis
Membrane
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
AP-2 adaptor complex
Molecular Function
Clathrin adaptor activity
Biological Process
Clathrin-dependent endocytosis
Biological Process
Intracellular protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Crn-1275Cryptococcus neoformans62.340.0 904
LLPS-Cogr-0406Colletotrichum graminicola61.920.0 790
LLPS-Ved-0481Verticillium dahliae61.880.0 623
LLPS-Dos-0930Dothistroma septosporum58.60.0 783
LLPS-Trr-0659Trichoderma reesei52.680.0 984
LLPS-Fuo-0739Fusarium oxysporum51.760.0 971
LLPS-Beb-0372Beauveria bassiana51.640.0 934
LLPS-Drm-0054Drosophila melanogaster51.340.0 593
LLPS-Xim-1759Xiphophorus maculatus51.310.0 601
LLPS-Zyt-0671Zymoseptoria tritici51.280.0 940
LLPS-Lem-0421Leptosphaeria maculans50.960.0 962
LLPS-Anp-1600Anas platyrhynchos50.670.0 590
LLPS-Meg-2316Meleagris gallopavo50.670.0 590
LLPS-Ova-0082Ovis aries50.570.0 617
LLPS-Sah-2822Sarcophilus harrisii50.50.0 590
LLPS-Fud-4299Fukomys damarensis50.50.0 585
LLPS-Aim-1871Ailuropoda melanoleuca50.50.0 590
LLPS-Tag-3052Taeniopygia guttata50.490.0 606
LLPS-Xet-3095Xenopus tropicalis50.480.0 607
LLPS-Cii-2188Ciona intestinalis50.410.0 594
LLPS-Man-4446Macaca nemestrina50.40.0 615
LLPS-Hos-3191Homo sapiens50.40.0 615
LLPS-Pap-3307Pan paniscus50.40.0 615
LLPS-Pat-3632Pan troglodytes50.40.0 615
LLPS-Otg-1098Otolemur garnettii50.40.0 616
LLPS-Cap-3664Cavia porcellus50.40.0 605
LLPS-Eqc-0394Equus caballus50.40.0 616
LLPS-Ten-3489Tetraodon nigroviridis50.40.0 607
LLPS-Cas-0906Carlito syrichta50.40.0 615
LLPS-Aon-2261Aotus nancymaae50.40.0 616
LLPS-Maf-4658Macaca fascicularis50.40.0 615
LLPS-Caj-3017Callithrix jacchus50.40.0 615
LLPS-Bot-2534Bos taurus50.40.0 616
LLPS-Mup-2789Mustela putorius furo50.40.0 616
LLPS-Paa-0524Papio anubis50.40.0 615
LLPS-Ran-3293Rattus norvegicus50.40.0 611
LLPS-Sus-3142Sus scrofa50.320.0 611
LLPS-Loa-2693Loxodonta africana50.250.0 584
LLPS-Nol-1526Nomascus leucogenys50.240.0 608
LLPS-Mum-3278Mus musculus50.240.0 605
LLPS-Mea-4405Mesocricetus auratus50.240.0 605
LLPS-Dio-3082Dipodomys ordii50.240.0 613
LLPS-Fec-1693Felis catus50.170.0 587
LLPS-Urm-3829Ursus maritimus50.170.0 560
LLPS-Orc-1248Oryctolagus cuniculus50.170.0 590
LLPS-Gaa-2844Gasterosteus aculeatus50.160.0 613
LLPS-Anc-1023Anolis carolinensis50.080.0 620
LLPS-Tut-0022Tursiops truncatus50.080.0 610
LLPS-Asc-0174Aspergillus clavatus50.050.0 951
LLPS-Lac-2525Latimeria chalumnae49.920.0 613
LLPS-Dar-2452Danio rerio49.920.0 610
LLPS-Tar-1888Takifugu rubripes49.920.0 610
LLPS-Ict-3205Ictidomys tridecemlineatus49.60.0 583
LLPS-Mal-3651Mandrillus leucophaeus49.60.0 592
LLPS-Chs-4609Chlorocebus sabaeus49.564e-138 441
LLPS-Cea-2938Cercocebus atys49.450.0 609
LLPS-Cis-1716Ciona savignyi49.420.0 584
LLPS-Caf-1989Canis familiaris49.30.0 615
LLPS-Poa-0079Pongo abelii49.30.0 599
LLPS-Cae-1642Caenorhabditis elegans49.270.0 580
LLPS-Myl-3116Myotis lucifugus49.20.0 583
LLPS-Orl-3513Oryzias latipes49.150.0 610
LLPS-Mod-0200Monodelphis domestica48.960.0 585
LLPS-Ast-0246Aspergillus terreus48.910.0 896
LLPS-Icp-3337Ictalurus punctatus48.90.0 615
LLPS-Gog-1434Gorilla gorilla48.880.0 576
LLPS-Pof-0250Poecilia formosa48.840.0 612
LLPS-Yal-0843Yarrowia lipolytica48.680.0 587
LLPS-Thc-1202Theobroma cacao48.340.0 572
LLPS-Pes-3101Pelodiscus sinensis48.310.0 593
LLPS-Sem-0989Selaginella moellendorffii48.20.0 574
LLPS-Nia-0864Nicotiana attenuata48.130.0 575
LLPS-Sob-0725Sorghum bicolor48.130.0 574
LLPS-Mua-0400Musa acuminata48.060.0 578
LLPS-Phv-1686Phaseolus vulgaris47.980.0 573
LLPS-Sei-1375Setaria italica47.970.0 574
LLPS-Zem-0005Zea mays47.80.0 570
LLPS-Sol-1799Solanum lycopersicum47.80.0 574
LLPS-Asm-1646Astyanax mexicanus47.760.0 611
LLPS-Rhb-4054Rhinopithecus bieti47.696e-171 530
LLPS-Ors-0800Oryza sativa47.674e-115 366
LLPS-Gor-2066Gossypium raimondii47.640.0 572
LLPS-Viv-0539Vitis vinifera47.640.0 573
LLPS-Mae-0708Manihot esculenta47.640.0 575
LLPS-Brr-1667Brassica rapa47.520.0 560
LLPS-Bro-2600Brassica oleracea47.520.0 561
LLPS-Amt-0489Amborella trichopoda47.480.0 575
LLPS-Brd-1987Brachypodium distachyon47.480.0 566
LLPS-Cus-1266Cucumis sativus47.480.0 570
LLPS-Glm-1214Glycine max47.330.0 573
LLPS-Orp-0164Oryza punctata47.320.0 568
LLPS-Prp-0803Prunus persica47.320.0 571
LLPS-Org-0426Oryza glaberrima47.320.0 568
LLPS-Lep-0588Leersia perrieri47.320.0 567
LLPS-Orgl-0690Oryza glumaepatula47.320.0 567
LLPS-Mam-1612Macaca mulatta47.280.0 563
LLPS-Scm-3508Scophthalmus maximus47.250.0 614
LLPS-Orn-1052Oreochromis niloticus47.250.0 617
LLPS-Ora-1673Ornithorhynchus anatinus47.23e-39 149
LLPS-Pot-1462Populus trichocarpa47.150.0 568
LLPS-Orbr-1750Oryza brachyantha47.150.0 567
LLPS-Coc-0697Corchorus capsularis47.150.0 568
LLPS-Php-0214Physcomitrella patens47.070.0 568
LLPS-Hea-1904Helianthus annuus46.910.0 569
LLPS-Tra-0733Triticum aestivum46.830.0 560
LLPS-Via-1403Vigna angularis46.633e-169 526
LLPS-Vir-1220Vigna radiata46.380.0 573
LLPS-Orr-2102Oryza rufipogon45.52e-170 536
LLPS-Orni-1499Oryza nivara45.52e-171 535
LLPS-Ori-1338Oryza indica45.41e-149 472
LLPS-Hov-0089Hordeum vulgare45.14e-177 551
LLPS-Tru-0097Triticum urartu44.951e-176 548
LLPS-Met-1855Medicago truncatula44.630.0 568
LLPS-Scj-0129Schizosaccharomyces japonicus43.867e-176 542
LLPS-Orb-0192Oryza barthii43.77e-160 503
LLPS-Dac-2331Daucus carota42.833e-159 501
LLPS-Fia-0339Ficedula albicollis41.780.0 744
LLPS-Gaga-2998Gallus gallus41.780.0 744
LLPS-Chr-0396Chlamydomonas reinhardtii41.754e-149 480
LLPS-Kop-1329Komagataella pastoris31.21e-78 281
LLPS-Leo-2321Lepisosteus oculatus25.114e-30 133