• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-0868
Aurka

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: aurora kinase A
Gene Name: Aurka
Ensembl Gene: ENSMAUG00000008679.1
Ensembl Protein: ENSMAUP00000006862.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, Nucleolus, PML nuclear body, Centrosome/Spindle pole body, OthersPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     SSRPVRITYT  LKVKPREMNS  PFGPKRVLVT  EQIPSQNLGL  ASSGQAQRVL  CPSNSSHRVP  60
61    SQAQKVVSGQ  KPVPKQLPPP  SVPRPEPQLS  NPQKSEQPPP  ADSGNNSESD  RASKQKTEDS  120
121   KKRQWTLQDF  DIGRPLGKGK  FGNVYLAREK  QSKFILALKV  LFKTQLEKAG  VEHQLRREVE  180
181   IQSHLRHPNI  LRLYGYFHDA  TRVYLILEYA  PLGTVYRELQ  KLSKFDEQRT  ATYITELANA  240
241   LSYCHSKRVI  HRDIKPENLL  LGPNRELKIA  DFGWSVHAPS  SRRTTLCGTL  DYLPPEMIEG  300
301   RMHDEKVDLW  SLGVLCYEFL  VGMPPFEAHT  HQETYRRISR  VEFTFPDFVT  EGARDLISRL  360
361   LKHNSSQRLT  LAEVLEHPWV  TAHSSKPSTC  QKTKELTSKS  S  401
Nucleotide CDS Sequence (FASTA)
1     ATGGACAGGT  GTAAAGAAAA  CTGTGTCTCC  AGGCCTGTTA  AGACTACAGG  TCCCTTCGGT  60
61    CCAAAACGAG  TCTTGGTGAC  AGAGCAGATT  CCTTCTCAGA  ACCTAGGATT  GGCTAGCAGT  120
121   GGCCAGGCCC  AGCGGGTCTT  GTGTCCTTCC  AACTCCTCCC  ATCGTGTCCC  TTCACAAGCA  180
181   CAGAAAGTTG  TCTCAGGTCA  GAAGCCAGTG  CCAAAGCAGT  TGCCACCTCC  CAGCGTTCCT  240
241   CGGCCCGAGC  CCCAGCTTAG  TAACCCCCAG  AAGAGTGAAC  AGCCACCCCC  TGCAGACTCT  300
301   GGAAATAATT  CTGAAAGTGA  TCGGGCATCA  AAGCAGAAAA  CTGAAGACTC  AAAAAAAAGG  360
361   CAGTGGACTC  TGCAAGACTT  TGACATTGGC  CGCCCGCTGG  GTAAAGGAAA  GTTTGGAAAT  420
421   GTCTACTTGG  CAAGGGAGAA  GCAAAGCAAG  TTCATCCTGG  CCCTGAAGGT  GCTGTTTAAG  480
481   ACACAGCTGG  AGAAGGCCGG  CGTGGAGCAC  CAGCTTCGGA  GGGAAGTGGA  GATCCAGTCC  540
541   CACCTGCGGC  ACCCCAACAT  CCTCAGGCTG  TATGGATATT  TCCATGATGC  CACCAGAGTT  600
601   TATCTAATTC  TAGAATACGC  GCCCCTTGGG  ACCGTCTACA  GAGAGCTCCA  GAAACTCTCC  660
661   AAGTTTGACG  AGCAGAGGAC  GGCTACATAC  ATCACGGAGT  TGGCAAACGC  TCTATCTTAC  720
721   TGTCACTCAA  AGAGAGTCAT  CCACAGAGAC  ATTAAGCCAG  AGAACCTGCT  TCTTGGGCCA  780
781   AATAGAGAGC  TGAAGATCGC  AGACTTTGGA  TGGTCTGTGC  ACGCTCCATC  TTCCAGGAGG  840
841   ACCACACTAT  GTGGCACCCT  GGACTACCTG  CCCCCTGAGA  TGATTGAAGG  CCGGATGCAC  900
901   GATGAGAAGG  TGGACCTCTG  GAGCCTGGGT  GTCCTCTGCT  ATGAGTTCCT  AGTTGGGATG  960
961   CCTCCTTTCG  AGGCACACAC  CCACCAGGAG  ACCTACAGGA  GGATATCACG  GGTTGAATTC  1020
1021  ACATTCCCTG  ACTTTGTGAC  TGAGGGAGCC  AGGGACCTCA  TTTCAAGACT  ACTAAAGCAC  1080
1081  AACTCAAGTC  AGAGGCTAAC  ACTAGCAGAG  GTCCTTGAGC  ACCCCTGGGT  CACAGCTCAC  1140
1141  TCTTCAAAAC  CTTCAACTTG  CCAAAAAACC  AAAGAGTTAA  CAAGCAAATC  ATCTTAG  1197

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ran-0231Rattus norvegicus89.180.0 676
LLPS-Mum-0427Mus musculus88.140.0 666
LLPS-Ora-0821Ornithorhynchus anatinus86.410.0 520
LLPS-Dio-1397Dipodomys ordii85.260.0 641
LLPS-Fud-3321Fukomys damarensis84.320.0 618
LLPS-Aon-1662Aotus nancymaae83.770.0 631
LLPS-Cas-1922Carlito syrichta82.980.0 629
LLPS-Mam-1921Macaca mulatta82.890.0 617
LLPS-Rhb-0371Rhinopithecus bieti82.80.0 566
LLPS-Aim-0753Ailuropoda melanoleuca82.790.0 610
LLPS-Cea-0958Cercocebus atys82.550.0 624
LLPS-Chs-3639Chlorocebus sabaeus82.550.0 624
LLPS-Paa-0614Papio anubis82.550.0 623
LLPS-Myl-1799Myotis lucifugus82.510.0 608
LLPS-Man-0266Macaca nemestrina82.290.0 622
LLPS-Pap-0394Pan paniscus82.290.0 626
LLPS-Pat-0269Pan troglodytes82.290.0 626
LLPS-Maf-2786Macaca fascicularis82.290.0 622
LLPS-Bot-1417Bos taurus82.290.0 618
LLPS-Ova-0278Ovis aries82.290.0 617
LLPS-Orc-1617Oryctolagus cuniculus82.20.0 621
LLPS-Fec-0403Felis catus82.030.0 629
LLPS-Hos-0651Homo sapiens82.030.0 625
LLPS-Caj-0149Callithrix jacchus81.840.0 622
LLPS-Gog-1941Gorilla gorilla81.770.0 625
LLPS-Cap-0539Cavia porcellus81.680.0 605
LLPS-Sus-2126Sus scrofa81.680.0 616
LLPS-Urm-1992Ursus maritimus81.510.0 629
LLPS-Nol-1379Nomascus leucogenys81.510.0 620
LLPS-Caf-0453Canis familiaris80.990.0 631
LLPS-Poa-0098Pongo abelii80.960.0 621
LLPS-Mup-0241Mustela putorius furo80.870.0 597
LLPS-Eqc-2662Equus caballus80.752e-139 412
LLPS-Otg-0306Otolemur garnettii80.470.0 614
LLPS-Ict-2231Ictidomys tridecemlineatus79.890.0 576
LLPS-Loa-0807Loxodonta africana79.690.0 598
LLPS-Mal-0254Mandrillus leucophaeus79.690.0 592
LLPS-Icp-1248Ictalurus punctatus77.616e-155 451
LLPS-Sah-1436Sarcophilus harrisii76.30.0 567
LLPS-Mod-0263Monodelphis domestica75.540.0 549
LLPS-Asm-0318Astyanax mexicanus75.545e-154 449
LLPS-Tag-0143Taeniopygia guttata73.586e-180 513
LLPS-Lac-2389Latimeria chalumnae73.485e-149 431
LLPS-Pes-0017Pelodiscus sinensis73.390.0 538
LLPS-Gaga-1598Gallus gallus71.990.0 517
LLPS-Cym-0237Cyanidioschyzon merolae71.971e-140 416
LLPS-Ere-0509Erinaceus europaeus71.481e-138 407
LLPS-Xet-0174Xenopus tropicalis71.321e-144 419
LLPS-Dar-0431Danio rerio70.339e-143 416
LLPS-Scf-1934Scleropages formosus69.512e-155 451
LLPS-Leo-0042Lepisosteus oculatus69.453e-143 419
LLPS-Pof-1359Poecilia formosa68.983e-141 411
LLPS-Osl-0960Ostreococcus lucimarinus68.822e-134 395
LLPS-Cii-1318Ciona intestinalis68.797e-143 416
LLPS-Anp-1760Anas platyrhynchos68.410.0 524
LLPS-Tar-1644Takifugu rubripes68.252e-137 405
LLPS-Org-0901Oryza glaberrima67.829e-126 372
LLPS-Gas-0604Galdieria sulphuraria67.69e-139 411
LLPS-Amt-0593Amborella trichopoda67.271e-131 387
LLPS-Viv-0559Vitis vinifera67.046e-129 380
LLPS-Sem-1439Selaginella moellendorffii67.043e-130 383
LLPS-Anc-3351Anolis carolinensis66.932e-169 489
LLPS-Orbr-0354Oryza brachyantha66.922e-125 371
LLPS-Cis-1210Ciona savignyi66.674e-141 412
LLPS-Ten-0906Tetraodon nigroviridis66.34e-135 395
LLPS-Fia-0465Ficedula albicollis66.175e-180 516
LLPS-Cus-0053Cucumis sativus66.121e-114 343
LLPS-Mua-0602Musa acuminata66.073e-129 381
LLPS-Bro-0803Brassica oleracea66.045e-126 374
LLPS-Gor-0973Gossypium raimondii65.941e-129 382
LLPS-Chr-0161Chlamydomonas reinhardtii65.832e-132 389
LLPS-Brn-2903Brassica napus65.794e-126 373
LLPS-Mae-0322Manihot esculenta65.684e-128 378
LLPS-Vir-1007Vigna radiata65.684e-127 375
LLPS-Phv-1445Phaseolus vulgaris65.583e-128 378
LLPS-Dac-0042Daucus carota65.583e-127 377
LLPS-Brr-0053Brassica rapa65.412e-125 371
LLPS-Art-0438Arabidopsis thaliana65.411e-126 374
LLPS-Glm-2276Glycine max65.221e-128 379
LLPS-Arl-0022Arabidopsis lyrata65.24e-129 380
LLPS-Lep-0151Leersia perrieri65.115e-128 378
LLPS-Ors-0006Oryza sativa64.875e-127 375
LLPS-Orr-0517Oryza rufipogon64.875e-127 375
LLPS-Thc-1505Theobroma cacao64.875e-128 378
LLPS-Sei-1392Setaria italica64.622e-126 374
LLPS-Php-0030Physcomitrella patens64.545e-131 385
LLPS-Chc-0164Chondrus crispus64.262e-127 376
LLPS-Tra-0508Triticum aestivum64.031e-125 372
LLPS-Orp-0380Oryza punctata63.964e-127 375
LLPS-Ori-0419Oryza indica63.968e-127 375
LLPS-Orni-0287Oryza nivara63.968e-127 375
LLPS-Orgl-0338Oryza glumaepatula63.962e-126 374
LLPS-Sob-1500Sorghum bicolor63.937e-127 375
LLPS-Tru-0796Triticum urartu63.83e-125 370
LLPS-Prp-0381Prunus persica63.793e-130 384
LLPS-Hea-0080Helianthus annuus63.671e-129 382
LLPS-Sot-1738Solanum tuberosum63.675e-130 383
LLPS-Coc-1508Corchorus capsularis63.647e-130 382
LLPS-Brd-0258Brachypodium distachyon63.484e-127 375
LLPS-Nia-0805Nicotiana attenuata63.259e-128 377
LLPS-Via-0913Vigna angularis63.253e-127 376
LLPS-Pot-1957Populus trichocarpa63.075e-129 380
LLPS-Scm-1017Scophthalmus maximus62.752e-140 411
LLPS-Sol-0010Solanum lycopersicum62.547e-131 385
LLPS-Orn-0681Oreochromis niloticus62.349e-136 399
LLPS-Xim-1814Xiphophorus maculatus62.096e-139 408
LLPS-Mel-0704Melampsora laricipopulina61.783e-114 348
LLPS-Met-0370Medicago truncatula61.547e-129 380
LLPS-Gaa-0192Gasterosteus aculeatus61.442e-136 400
LLPS-Orl-1796Oryzias latipes61.291e-137 404
LLPS-Hov-0048Hordeum vulgare61.288e-127 375
LLPS-Meg-0376Meleagris gallopavo60.751e-139 411
LLPS-Scp-0044Schizosaccharomyces pombe60.222e-119 358
LLPS-Pug-0774Puccinia graminis59.933e-118 357
LLPS-Scj-0231Schizosaccharomyces japonicus59.852e-116 350
LLPS-Scc-0017Schizosaccharomyces cryophilus58.897e-117 352
LLPS-Cae-0311Caenorhabditis elegans57.655e-118 353
LLPS-Zem-0384Zea mays57.376e-119 356
LLPS-Drm-0012Drosophila melanogaster56.952e-120 363