LLPS-Man-0430
STAT3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Signal transducer and activator of transcription |
| Gene Name: | STAT3 |
| Ensembl Gene: | ENSMNEG00000033376.1 |
| Ensembl Protein: | ENSMNEP00000019009.1 |
| Organism: | Macaca nemestrina |
| Taxa ID: | 9545 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Chromatin, Nuclear pore complex, Nuclear speckle, PML nuclear body, Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMNET00000043249.1 | ENSMNEP00000019009.1 |
| UniProt | A0A2K6C5T8, A0A2K6C5T8_MACNE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAASKE SHATLVFHNL 60 61 LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME IARIVARCLW EESRLLQTAA 120 121 TAAQQGGQAN HPTAAVVTEK QQMLEQHLQD VRKRVQITSL AESQLQTRQQ IKKLEELQQK 180 181 VSYKGDPIVQ HRPMLEERIV ELFRNLMKSA FVVERQPCMP MHPDRPLVIK TGVQFTTKVR 240 241 LLVKFPELNY QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN NGSLSAEFKH 300 301 LTLREQRCGN GGRANCDASL IVTEELHLIT FETEVYHQGL KIDLETHSLP VVVISNICQM 360 361 PNAWASILWY NMLTNNPKNV NFFTKPPIGT WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE 420 421 KLLGPGVNYS GCQITWAKFC KENMAGKGFS FWVWLDNIID LVKKYILALW NEGYIMGFIS 480 481 KERERAILST KPPGTFLLRF SESSKEGGVT FTWVEKDISG KTQIQSVEPY TKQQLNNMSF 540 541 AEIIMGYKIM DATNILVSPL VYLYPDIPKE EAFGKYCRPE SQEHPEADPG SAAPYLKTKF 600 601 ICVTPTTCSN TIDLPMSPRT LDSLMQFGNN GEGAEPSAGG QFESLTFDME LTSECATSPM 660 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCCAAT GGAATCAGCT ACAGCAGCTT GACACACGGT ACCTGGAGCA GCTCCATCAG 60 61 CTCTACAGTG ACAGCTTCCC AATGGAGTTG CGGCAGTTTC TGGCCCCTTG GATTGAGAGT 120 121 CAAGATTGGG CATATGCGGC CAGCAAAGAA TCACATGCCA CTTTGGTGTT TCATAATCTC 180 181 CTGGGCGAGA TTGACCAGCA GTATAGCCGC TTCCTGCAAG AGTCGAATGT TCTCTATCAG 240 241 CACAATCTAC GAAGAATCAA GCAGTTTCTT CAGAGCAGGT ATCTTGAGAA GCCAATGGAG 300 301 ATTGCCCGGA TTGTGGCCCG GTGCCTGTGG GAAGAGTCAC GCCTCCTACA GACTGCAGCC 360 361 ACTGCGGCCC AGCAAGGGGG CCAGGCCAAC CACCCCACAG CAGCTGTGGT GACGGAGAAG 420 421 CAGCAGATGC TGGAGCAGCA CCTTCAGGAT GTCCGGAAGA GAGTACAGAT AACGTCATTA 480 481 GCAGAATCTC AACTTCAGAC CCGTCAACAA ATTAAGAAAC TGGAGGAGTT GCAGCAAAAA 540 541 GTGTCCTACA AAGGGGACCC CATTGTACAA CACCGGCCGA TGCTGGAGGA GAGAATCGTG 600 601 GAGCTGTTCA GAAACTTAAT GAAAAGTGCC TTTGTGGTGG AGCGGCAGCC CTGCATGCCC 660 661 ATGCATCCCG ACCGGCCCCT TGTCATCAAG ACCGGCGTCC AGTTCACTAC CAAAGTCAGG 720 721 TTGCTGGTCA AATTCCCTGA GTTAAATTAT CAACTTAAAA TTAAAGTGTG CATTGACAAA 780 781 GACTCCGGGG ATGTTGCAGC TCTCAGAGGA TCCCGGAAAT TTAACATTCT GGGCACAAAC 840 841 ACCAAAGTGA TGAACATGGA AGAGTCCAAC AACGGCAGCC TCTCTGCAGA ATTCAAACAC 900 901 TTGACCCTGA GGGAGCAGAG ATGTGGGAAT GGGGGCCGAG CCAATTGTGA TGCTTCCCTG 960 961 ATTGTGACTG AGGAGCTGCA CCTGATCACC TTTGAGACAG AGGTATATCA CCAAGGCCTC 1020 1021 AAGATTGACC TAGAGACCCA CTCCTTGCCA GTTGTGGTGA TCTCCAACAT CTGTCAGATG 1080 1081 CCAAATGCCT GGGCGTCCAT CCTGTGGTAC AACATGCTGA CCAACAACCC CAAGAACGTA 1140 1141 AACTTTTTTA CCAAGCCCCC AATCGGAACC TGGGATCAAG TGGCCGAGGT CCTGAGCTGG 1200 1201 CAGTTCTCCT CCACCACCAA GCGAGGACTG AGCATCGAGC AGCTGACTAC ACTGGCGGAG 1260 1261 AAACTCTTGG GACCTGGCGT GAATTATTCA GGGTGTCAGA TCACATGGGC TAAATTTTGC 1320 1321 AAAGAAAACA TGGCTGGCAA GGGCTTCTCC TTCTGGGTCT GGCTGGACAA TATCATTGAC 1380 1381 CTTGTGAAAA AGTACATCCT GGCCCTTTGG AATGAAGGGT ACATCATGGG CTTTATCAGT 1440 1441 AAGGAGCGGG AGCGGGCCAT CTTGAGCACC AAGCCTCCAG GCACCTTTCT GCTAAGATTC 1500 1501 AGTGAAAGCA GCAAAGAAGG CGGCGTCACT TTCACTTGGG TGGAGAAGGA CATCAGTGGT 1560 1561 AAGACCCAGA TCCAGTCCGT GGAACCATAC ACCAAGCAGC AGTTGAACAA CATGTCATTT 1620 1621 GCTGAAATCA TCATGGGATA TAAGATCATG GATGCTACCA ATATTCTGGT GTCTCCGCTG 1680 1681 GTCTATCTCT ACCCTGACAT TCCCAAGGAG GAGGCATTCG GAAAGTATTG TCGGCCAGAG 1740 1741 AGCCAGGAGC ATCCTGAAGC TGACCCAGGT AGCGCCGCCC CATACCTGAA GACCAAGTTT 1800 1801 ATCTGTGTGA CACCAACGAC CTGCAGCAAT ACCATTGACC TGCCGATGTC CCCCCGCACT 1860 1861 TTAGATTCAT TGATGCAGTT TGGAAATAAT GGTGAAGGTG CTGAACCCTC AGCAGGAGGG 1920 1921 CAGTTTGAGT CCCTCACCTT TGACATGGAG TTGACCTCGG AGTGTGCTAC CTCCCCCATG 1980 1981 TGA 1983 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Gog-0352 | Gorilla gorilla | 100.0 | 2e-87 | 296 |
| LLPS-Fud-2849 | Fukomys damarensis | 100.0 | 1e-87 | 296 |
| LLPS-Caj-3055 | Callithrix jacchus | 100.0 | 1e-87 | 296 |
| LLPS-Mum-2071 | Mus musculus | 100.0 | 1e-87 | 296 |
| LLPS-Maf-0552 | Macaca fascicularis | 100.0 | 4e-87 | 296 |
| LLPS-Mea-2711 | Mesocricetus auratus | 100.0 | 1e-54 | 204 |
| LLPS-Chs-2888 | Chlorocebus sabaeus | 100.0 | 0.0 | 1034 |
| LLPS-Sus-0271 | Sus scrofa | 100.0 | 1e-87 | 296 |
| LLPS-Aon-2411 | Aotus nancymaae | 100.0 | 3e-87 | 296 |
| LLPS-Sah-0614 | Sarcophilus harrisii | 100.0 | 1e-87 | 296 |
| LLPS-Cea-1181 | Cercocebus atys | 100.0 | 0.0 | 1033 |
| LLPS-Ran-2567 | Rattus norvegicus | 100.0 | 1e-87 | 296 |
| LLPS-Paa-2240 | Papio anubis | 100.0 | 1e-87 | 296 |
| LLPS-Myl-2630 | Myotis lucifugus | 100.0 | 1e-87 | 296 |
| LLPS-Ova-3472 | Ovis aries | 100.0 | 2e-87 | 297 |
| LLPS-Aim-3816 | Ailuropoda melanoleuca | 100.0 | 1e-87 | 296 |
| LLPS-Mup-1659 | Mustela putorius furo | 100.0 | 0.0 | 1035 |
| LLPS-Bot-3316 | Bos taurus | 100.0 | 1e-87 | 296 |
| LLPS-Orc-1151 | Oryctolagus cuniculus | 100.0 | 1e-87 | 296 |
| LLPS-Hos-2566 | Homo sapiens | 100.0 | 0.0 | 1034 |
| LLPS-Pap-2559 | Pan paniscus | 100.0 | 2e-87 | 296 |
| LLPS-Urm-1504 | Ursus maritimus | 100.0 | 0.0 | 1030 |
| LLPS-Pat-0992 | Pan troglodytes | 100.0 | 2e-87 | 296 |
| LLPS-Mod-0940 | Monodelphis domestica | 100.0 | 4e-87 | 296 |
| LLPS-Fec-3339 | Felis catus | 100.0 | 0.0 | 1034 |
| LLPS-Loa-0314 | Loxodonta africana | 100.0 | 1e-87 | 296 |
| LLPS-Cas-0450 | Carlito syrichta | 100.0 | 3e-91 | 297 |
| LLPS-Nol-2118 | Nomascus leucogenys | 100.0 | 0.0 | 1034 |
| LLPS-Poa-0801 | Pongo abelii | 100.0 | 1e-87 | 296 |
| LLPS-Cap-3478 | Cavia porcellus | 100.0 | 1e-87 | 296 |
| LLPS-Eqc-3915 | Equus caballus | 100.0 | 0.0 | 1027 |
| LLPS-Dio-1489 | Dipodomys ordii | 99.8 | 0.0 | 1031 |
| LLPS-Ict-0585 | Ictidomys tridecemlineatus | 99.8 | 0.0 | 1025 |
| LLPS-Otg-4687 | Otolemur garnettii | 99.6 | 0.0 | 1031 |
| LLPS-Caf-0169 | Canis familiaris | 99.6 | 0.0 | 1031 |
| LLPS-Fia-0261 | Ficedula albicollis | 99.36 | 6e-87 | 295 |
| LLPS-Anc-2043 | Anolis carolinensis | 99.36 | 4e-87 | 295 |
| LLPS-Tag-0564 | Taeniopygia guttata | 99.36 | 4e-87 | 295 |
| LLPS-Meg-1678 | Meleagris gallopavo | 98.72 | 2e-86 | 293 |
| LLPS-Gaga-1090 | Gallus gallus | 98.72 | 2e-86 | 293 |
| LLPS-Mam-0418 | Macaca mulatta | 98.7 | 5e-83 | 284 |
| LLPS-Xet-1123 | Xenopus tropicalis | 96.15 | 2e-82 | 288 |
| LLPS-Anp-2332 | Anas platyrhynchos | 92.31 | 3e-76 | 264 |
| LLPS-Lac-0641 | Latimeria chalumnae | 91.56 | 0.0 | 879 |
| LLPS-Scf-2220 | Scleropages formosus | 89.1 | 9e-77 | 267 |
| LLPS-Rhb-0210 | Rhinopithecus bieti | 87.33 | 0.0 | 866 |
| LLPS-Leo-2471 | Lepisosteus oculatus | 87.29 | 0.0 | 905 |
| LLPS-Asm-2444 | Astyanax mexicanus | 87.18 | 1e-75 | 265 |
| LLPS-Tar-2090 | Takifugu rubripes | 87.18 | 4e-75 | 263 |
| LLPS-Dar-1615 | Danio rerio | 87.18 | 1e-75 | 265 |
| LLPS-Gaa-0547 | Gasterosteus aculeatus | 86.54 | 2e-75 | 264 |
| LLPS-Scm-0099 | Scophthalmus maximus | 86.54 | 2e-75 | 264 |
| LLPS-Orl-0386 | Oryzias latipes | 85.9 | 5e-76 | 265 |
| LLPS-Xim-1442 | Xiphophorus maculatus | 85.9 | 6e-76 | 265 |
| LLPS-Orn-0517 | Oreochromis niloticus | 85.9 | 1e-75 | 264 |
| LLPS-Pof-1300 | Poecilia formosa | 85.9 | 6e-76 | 265 |
| LLPS-Icp-2361 | Ictalurus punctatus | 85.47 | 0.0 | 885 |
| LLPS-Mal-3330 | Mandrillus leucophaeus | 74.55 | 0.0 | 1029 |
| LLPS-Ten-0724 | Tetraodon nigroviridis | 56.69 | 9e-172 | 516 |
| LLPS-Pes-3622 | Pelodiscus sinensis | 47.56 | 2e-124 | 405 |
| LLPS-Tut-2315 | Tursiops truncatus | 34.17 | 6e-10 | 66.6 |
| LLPS-Ora-1916 | Ornithorhynchus anatinus | 32.04 | 2e-44 | 171 |