LLPS-Mam-1368
APOE
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Apolipoprotein E |
| Gene Name: | APOE |
| Ensembl Gene: | ENSMMUG00000014305.3 |
| Ensembl Protein: | ENSMMUP00000018786.3 |
| Organism: | Macaca mulatta |
| Taxa ID: | 9544 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMMUT00000020072.3 | ENSMMUP00000018786.3 |
| Ensembl | ENSMMUT00000058138.1 | ENSMMUP00000048554.1 |
| Ensembl | ENSMMUT00000067524.1 | ENSMMUP00000059142.1 |
| UniProt | I2CYL7, I2CYL7_MACMU | |
| GeneBank | JV667389, JSUE03021868 | , AFJ72052.1 |
| RefSeq | XM_015124241.1 | XP_014979727.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKVLWAALLV TFLAGCQAKV EQPVEPETEP ELRQQAEGQS GQPWELALGR FWDYLRWVQT 60 61 LSEQVQEELL SPQVTQELTT LMDETMKELK AYKSELEEQL SPVAEETRAR LSKELQAAQA 120 121 RLGADMEDVR SRLVQYRSEV QAMLGQSTEE LRARLASHLR KLRKRLLRDA DDLQKRLAVY 180 181 QAGAREGAER GVSAIRERLG PLVEQGRVRA ATVGSLASQP LQERAQALGE RLRARMEEMG 240 241 SRTRDRLDEV KEQVAEVRAK LEEQAQQISL QAEAFQARLK SWFEPLVEDM QRQWAGLVEK 300 301 VQAAVGASTA PVPSDNH 317 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGCTCAG GGCCCTGGCC TCCAGACTGG CCAATCACAG GCAGGAAGAT GAAGGTTCTG 60 61 TGGGCTGCGT TGCTGGTCAC ATTCCTGGCA GGATGCCAGG CCAAGGTGGA GCAACCGGTG 120 121 GAGCCAGAGA CGGAACCCGA GCTTCGCCAG CAGGCTGAGG GGCAGAGCGG CCAGCCCTGG 180 181 GAGCTGGCAC TGGGTCGCTT TTGGGATTAC CTGCGCTGGG TGCAGACACT GTCTGAGCAG 240 241 GTGCAGGAGG AGCTGCTCAG CCCCCAGGTC ACCCAGGAAC TGACGACGCT GATGGATGAG 300 301 ACCATGAAGG AGTTGAAGGC CTACAAATCG GAACTGGAGG AACAGCTGAG CCCGGTGGCG 360 361 GAGGAGACGC GGGCACGGCT GTCCAAGGAG CTACAGGCGG CGCAGGCCCG GCTGGGTGCC 420 421 GACATGGAGG ACGTGCGCAG CCGCCTGGTG CAGTACCGCA GCGAGGTGCA GGCCATGCTG 480 481 GGCCAGAGTA CCGAGGAGCT GCGGGCGCGC CTCGCCTCCC ACCTGCGCAA GCTGCGCAAG 540 541 CGGCTCCTCC GCGATGCTGA TGACCTGCAG AAGCGCCTGG CAGTGTATCA GGCCGGGGCC 600 601 CGCGAGGGCG CCGAGCGTGG GGTCAGCGCC ATCCGCGAGC GCCTGGGACC CCTGGTGGAG 660 661 CAGGGCCGCG TGCGGGCCGC CACTGTGGGC TCCCTGGCCA GCCAGCCGCT TCAGGAGCGG 720 721 GCCCAGGCCT TGGGTGAGCG GCTTCGCGCA CGGATGGAGG AGATGGGCAG CCGGACC 777 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Man-3991 | Macaca nemestrina | 100.0 | 0.0 | 527 |
| LLPS-Maf-1827 | Macaca fascicularis | 100.0 | 0.0 | 527 |
| LLPS-Paa-3152 | Papio anubis | 99.68 | 0.0 | 523 |
| LLPS-Chs-0229 | Chlorocebus sabaeus | 99.05 | 0.0 | 518 |
| LLPS-Cea-2931 | Cercocebus atys | 98.42 | 0.0 | 516 |
| LLPS-Rhb-0795 | Rhinopithecus bieti | 97.48 | 0.0 | 511 |
| LLPS-Poa-4468 | Pongo abelii | 94.32 | 1e-173 | 491 |
| LLPS-Pap-2285 | Pan paniscus | 94.32 | 3e-174 | 493 |
| LLPS-Pat-1114 | Pan troglodytes | 94.32 | 3e-174 | 493 |
| LLPS-Hos-0967 | Homo sapiens | 93.69 | 2e-172 | 488 |
| LLPS-Caj-2708 | Callithrix jacchus | 90.62 | 2e-168 | 478 |
| LLPS-Nol-0037 | Nomascus leucogenys | 87.07 | 9e-149 | 428 |
| LLPS-Otg-4113 | Otolemur garnettii | 81.45 | 7e-145 | 418 |
| LLPS-Bot-1420 | Bos taurus | 75.0 | 4e-122 | 361 |
| LLPS-Ran-4859 | Rattus norvegicus | 74.04 | 4e-123 | 364 |
| LLPS-Fec-3304 | Felis catus | 73.85 | 3e-106 | 319 |
| LLPS-Mup-0859 | Mustela putorius furo | 73.67 | 5e-129 | 378 |
| LLPS-Tut-1541 | Tursiops truncatus | 73.5 | 5e-131 | 383 |
| LLPS-Sus-2619 | Sus scrofa | 73.18 | 1e-124 | 367 |
| LLPS-Mea-1347 | Mesocricetus auratus | 72.93 | 2e-132 | 387 |
| LLPS-Aon-1141 | Aotus nancymaae | 72.31 | 1e-130 | 380 |
| LLPS-Cap-0067 | Cavia porcellus | 72.29 | 8e-125 | 366 |
| LLPS-Eqc-1143 | Equus caballus | 72.24 | 4e-127 | 373 |
| LLPS-Ova-4225 | Ovis aries | 70.98 | 2e-124 | 366 |
| LLPS-Mum-3610 | Mus musculus | 70.13 | 8e-131 | 382 |
| LLPS-Loa-3477 | Loxodonta africana | 70.03 | 1e-125 | 369 |
| LLPS-Caf-1692 | Canis familiaris | 69.91 | 3e-122 | 361 |
| LLPS-Fud-4360 | Fukomys damarensis | 68.0 | 3e-58 | 193 |
| LLPS-Aim-0812 | Ailuropoda melanoleuca | 66.78 | 3e-105 | 317 |
| LLPS-Myl-2614 | Myotis lucifugus | 64.89 | 6e-111 | 332 |
| LLPS-Dio-3677 | Dipodomys ordii | 64.47 | 6e-107 | 320 |
| LLPS-Mod-2122 | Monodelphis domestica | 48.74 | 3e-59 | 198 |
| LLPS-Sah-3036 | Sarcophilus harrisii | 45.76 | 2e-40 | 147 |
| LLPS-Ora-3487 | Ornithorhynchus anatinus | 41.44 | 8e-51 | 176 |
| LLPS-Leo-2501 | Lepisosteus oculatus | 32.71 | 2e-13 | 71.2 |
| LLPS-Dar-3412 | Danio rerio | 29.14 | 3e-21 | 95.5 |
| LLPS-Orn-2719 | Oreochromis niloticus | 29.11 | 6e-24 | 103 |
| LLPS-Gaa-0219 | Gasterosteus aculeatus | 28.27 | 2e-20 | 93.2 |
| LLPS-Tar-2210 | Takifugu rubripes | 27.71 | 2e-18 | 87.0 |
| LLPS-Lac-3372 | Latimeria chalumnae | 27.51 | 6e-27 | 112 |
| LLPS-Scm-0225 | Scophthalmus maximus | 27.04 | 2e-21 | 95.9 |
| LLPS-Scf-1952 | Scleropages formosus | 26.64 | 5e-24 | 103 |
| LLPS-Asm-2917 | Astyanax mexicanus | 26.49 | 1e-21 | 96.7 |
| LLPS-Icp-2604 | Ictalurus punctatus | 26.03 | 1e-20 | 94.0 |
| LLPS-Xet-2377 | Xenopus tropicalis | 24.71 | 1e-18 | 87.8 |