LLPS-Mal-4709
PYGM
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Alpha-1,4 glucan phosphorylase |
| Gene Name: | PYGM |
| Ensembl Gene: | ENSMLEG00000033335.1 |
| Ensembl Protein: | ENSMLEP00000018812.1 |
| Organism: | Mandrillus leucophaeus |
| Taxa ID: | 9568 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSMLET00000042299.1 | ENSMLEP00000018812.1 |
| Ensembl | ENSMLET00000042329.1 | ENSMLEP00000018842.1 |
| Ensembl | ENSMLET00000042334.1 | ENSMLEP00000018847.1 |
| Ensembl | ENSMLET00000042304.1 | ENSMLEP00000018817.1 |
| UniProt | A0A2K5YTB5, A0A2K5YTB5_MANLE | |
| RefSeq | XM_011993507.1 | XP_011848897.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSRPLSDQEK RKQISVRGLA GVENVTELKK NFNRHLHFTL VKDRNVATPR DYYFALAHTV 60 61 RDHLVGRWIR TQQHYYEKDP KRIYYLSLEF YMGRTLQNTM VNLALENACD EATYQLGLDM 120 121 EELEEIEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEFGIFNQK ISGGWQMEEA 180 181 DDWLRYGNPW EKARPEFTLP VHFYGHVEHT SQGAKWVDTQ VVLAMPYDTP VPGYRNNIVN 240 241 TMRLWSAKAP NDFNLKDFNV GGYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV 300 301 VAATLQDIIR RFKSSKFGCR DPVRTNFDAF PDKVAIQLND THPSLAIPEL MRILVDLERM 360 361 DWDKAWDVTV RTCAYTNHTV LPEALERWPV HLLETLLPRH LQIIYEINQR FLNRVAATFP 420 421 GDVDRLRRMS LVEEGAVKRI NMAHLCIAGS HAVNGVARIH SEILKKTIFK DFYELEPHKF 480 481 QNKTNGITPR RWLVLCNPGL AEVIAERIGE DFISDLDQLR KLLSFVDDEA FIRDVAKVKQ 540 541 ENKLKFAAYL EREYKVHINP NSLFDIQVKR IHEYKRQLLN CLHVITLYNR IKREPNKFFV 600 601 PRTVMIGGKA APGYHMAKMI IRLITAIGDV VNHDPTVGDR LRVIFLENYR VSLAEKVIPA 660 661 ADLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM AEEAGEENFF IFGMRVEDVD 720 721 KLDQRGYNAQ EYYDRIPELR QVIEQLSSGF FSPKQPDLFK DIVNMLMHHD RFKVFADYED 780 781 YIKCQEKVSA LYKNPREWTR MVIRNIATSG KFSSDRTIAQ YAREIWGVEP SRQRLPAPDE 840 841 AI 842 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCCCGGC CCCTGTCAGA CCAGGAGAAA AGAAAGCAAA TCAGTGTGCG TGGCCTGGCC 60 61 GGCGTGGAGA ATGTGACTGA GCTGAAAAAG AACTTCAACC GGCACCTGCA TTTCACACTC 120 121 GTAAAGGACC GCAATGTGGC CACCCCACGA GACTACTACT TTGCACTGGC CCATACCGTG 180 181 CGCGACCACC TCGTGGGGCG CTGGATCCGC ACGCAGCAAC ACTACTACGA GAAGGACCCC 240 241 AAGGTGCTGC TGGGGACACC TGGGGTGGGG ATGGAGGAGG CTGATGACTG GCTTCGCTAC 300 301 GGCAACCCCT GGGAGAAGGC CCGCCCCGAG TTCACACTAC CTGTGCACTT CTACGGCCAT 360 361 GTGGAGCACA CCAGCCAGGG TGCCAAGTGG GTGGACACAC AGGTGGTACT GGCCATGCCC 420 421 TACGATACGC CCGTGCCCGG CTATCGCAAC AACATCGTCA ACACCATGCG CCTCTGGTCT 480 481 GCCAAGGCTC CCAATGACTT CAACCTCAAG GACTTCAACG TCGGTGGCTA CATCCAGGCT 540 541 GTGTTGGACC GAAACCTGGC AGAGAACATC TCTCGTGTCT TGTACCCCAA TGATAATTTC 600 601 TTCGAAGGGA AGGAGCTGCG GCTGAAGCAG GAGTATTTCG TGGTGGCCGC CACCCTCCAG 660 661 GACATCATCC GTCGCTTCAA GTCCTCCAAG TTCGGCTGCC GCGATCCCGT GCGCACGAAC 720 721 TTCGATGCCT TCCCAGACAA GGTAGCCATC CAGCTCAATG ACACCCACCC CTCCCTGGCC 780 781 ATCCCCGAAC TGATGAGGAT CCTGGTGGAC CTGGAGCGGA TGGACTGGGA TAAGGCATGG 840 841 GATGTGACAG TGAGGACCTG TGCCTACACC AACCACACGG TGCTGCCTGA GGCCCTGGAG 900 901 CGCTGGCCGG TACACCTCTT GGAGACGCTG CTGCCGCGGC ACCTCCAGAT CATCTACGAG 960 961 ATCAACCAGC GCTTCCTCAA CCGGGTGGCA GCCACATTCC CAGGGGACGT AGACAGGCTG 1020 1021 CGGCGCATGT CGCTGGTGGA GGAGGGCGCA GTGAAGCGCA TCAACATGGC ACACCTGTGC 1080 1081 ATCGCGGGTT CGCACGCTGT CAACGGTGTG GCGCGCATCC ACTCCGAGAT CCTCAAGAAG 1140 1141 ACCATCTTCA AAGACTTCTA TGAGCTGGAG CCTCATAAGT TCCAGAATAA GACCAACGGC 1200 1201 ATCACCCCTC GGCGCTGGCT GGTTCTGTGT AACCCCGGGC TGGCAGAGGT CATTGCTGAG 1260 1261 CGCATTGGGG AGGACTTCAT CTCCGACCTG GACCAGCTGC GCAAATTGCT CTCCTTTGTG 1320 1321 GATGATGAAG CTTTCATTCG GGATGTGGCC AAAGTGAAGC AGGAAAACAA GTTGAAGTTT 1380 1381 GCTGCCTACC TAGAGAGGGA ATACAAAGTC CACATCAACC CCAACTCACT CTTCGACATC 1440 1441 CAGGTGAAGC GGATTCACGA ATATAAACGA CAGCTCCTCA ACTGCCTCCA TGTCATCACC 1500 1501 CTGTATAATC GCATCAAGAG GGAGCCCAAT AAGTTTTTTG TGCCTCGGAC TGTGATGATT 1560 1561 GGAGGGAAGG CTGCACCTGG GTACCACATG GCCAAGATGA TCATCAGACT CATCACAGCC 1620 1621 ATTGGGGATG TGGTCAACCA TGACCCGACA GTGGGTGACC GCCTCCGTGT CATCTTCCTG 1680 1681 GAGAACTACC GAGTCTCACT GGCCGAGAAA GTGATCCCAG CTGCAGACCT CTCTGAGCAG 1740 1741 ATCTCCACTG CGGGCACTGA GGCCTCAGGC ACCGGCAACA TGAAGTTCAT GCTCAACGGG 1800 1801 GCTCTGACCA TTGGCACCAT GGACGGGGCC AATGTGGAGA TGGCAGAAGA GGCTGGAGAG 1860 1861 GAAAACTTCT TCATCTTTGG CATGCGGGTG GAGGATGTGG ATAAGCTTGA CCAAAGAGGG 1920 1921 TACAATGCCC AGGAGTACTA TGACCGCATT CCTGAGCTTC GGCAGGTCAT TGAGCAGCTG 1980 1981 AGCAGTGGCT TCTTCTCCCC CAAACAGCCC GACCTGTTCA AGGACATTGT CAATATGCTT 2040 2041 ATGCACCATG ACCGGTTTAA AGTCTTCGCA GATTATGAAG ACTACATTAA ATGCCAGGAG 2100 2101 AAAGTCAGTG CCTTGTACAA GAACCCAAGA GAGTGGACGC GGATGGTGAT CCGGAACATA 2160 2161 GCCACCTCTG GCAAGTTCTC CAGTGACCGC ACCATTGCCC AGTATGCCCG GGAGATCTGG 2220 2221 GGTGTGGAGC CTTCCCGCCA GCGCCTGCCA GCCCCGGATG AGGCCATCTG A 2271 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | Glycogen phosphorylase activity | |
Molecular Function | Linear malto-oligosaccharide phosphorylase activity | |
Molecular Function | Pyridoxal phosphate binding | |
Molecular Function | SHG alpha-glucan phosphorylase activity | |
Biological Process | Glycogen catabolic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Paa-3577 | Papio anubis | 99.88 | 0.0 | 1706 |
| LLPS-Cea-3027 | Cercocebus atys | 99.88 | 0.0 | 1706 |
| LLPS-Maf-3548 | Macaca fascicularis | 99.88 | 0.0 | 1706 |
| LLPS-Mam-2687 | Macaca mulatta | 99.88 | 0.0 | 1706 |
| LLPS-Man-4055 | Macaca nemestrina | 99.88 | 0.0 | 1706 |
| LLPS-Rhb-3619 | Rhinopithecus bieti | 99.76 | 0.0 | 1704 |
| LLPS-Hos-4966 | Homo sapiens | 99.52 | 0.0 | 1702 |
| LLPS-Pap-3858 | Pan paniscus | 99.52 | 0.0 | 1702 |
| LLPS-Pat-2921 | Pan troglodytes | 99.41 | 0.0 | 1700 |
| LLPS-Poa-3167 | Pongo abelii | 99.17 | 0.0 | 1697 |
| LLPS-Caj-1868 | Callithrix jacchus | 98.93 | 0.0 | 1696 |
| LLPS-Aon-2870 | Aotus nancymaae | 98.81 | 0.0 | 1695 |
| LLPS-Gog-4002 | Gorilla gorilla | 97.98 | 0.0 | 1692 |
| LLPS-Aim-1024 | Ailuropoda melanoleuca | 97.62 | 0.0 | 1669 |
| LLPS-Ict-2498 | Ictidomys tridecemlineatus | 97.62 | 0.0 | 1677 |
| LLPS-Caf-0336 | Canis familiaris | 97.62 | 0.0 | 1676 |
| LLPS-Mup-3137 | Mustela putorius furo | 97.51 | 0.0 | 1675 |
| LLPS-Fec-0488 | Felis catus | 97.51 | 0.0 | 1675 |
| LLPS-Cap-0935 | Cavia porcellus | 97.39 | 0.0 | 1676 |
| LLPS-Orc-3834 | Oryctolagus cuniculus | 97.27 | 0.0 | 1675 |
| LLPS-Otg-2499 | Otolemur garnettii | 97.14 | 0.0 | 1662 |
| LLPS-Dio-3494 | Dipodomys ordii | 97.03 | 0.0 | 1670 |
| LLPS-Fud-2770 | Fukomys damarensis | 96.79 | 0.0 | 1668 |
| LLPS-Mum-4530 | Mus musculus | 96.79 | 0.0 | 1669 |
| LLPS-Eqc-1387 | Equus caballus | 96.79 | 0.0 | 1667 |
| LLPS-Ran-2211 | Rattus norvegicus | 96.56 | 0.0 | 1668 |
| LLPS-Loa-3923 | Loxodonta africana | 96.55 | 0.0 | 1665 |
| LLPS-Myl-3998 | Myotis lucifugus | 95.96 | 0.0 | 1654 |
| LLPS-Ova-0928 | Ovis aries | 95.72 | 0.0 | 1655 |
| LLPS-Sus-3405 | Sus scrofa | 95.72 | 0.0 | 1642 |
| LLPS-Bot-2636 | Bos taurus | 95.61 | 0.0 | 1655 |
| LLPS-Mod-3766 | Monodelphis domestica | 95.49 | 0.0 | 1644 |
| LLPS-Tut-1208 | Tursiops truncatus | 94.66 | 0.0 | 1639 |
| LLPS-Cas-2685 | Carlito syrichta | 92.52 | 0.0 | 1619 |
| LLPS-Pes-3556 | Pelodiscus sinensis | 89.52 | 0.0 | 1556 |
| LLPS-Pof-0814 | Poecilia formosa | 84.76 | 0.0 | 1487 |
| LLPS-Xim-2042 | Xiphophorus maculatus | 84.29 | 0.0 | 1481 |
| LLPS-Tar-3858 | Takifugu rubripes | 84.05 | 0.0 | 1475 |
| LLPS-Ten-0197 | Tetraodon nigroviridis | 84.05 | 0.0 | 1463 |
| LLPS-Asm-3284 | Astyanax mexicanus | 83.81 | 0.0 | 1471 |
| LLPS-Sah-4019 | Sarcophilus harrisii | 83.79 | 0.0 | 1322 |
| LLPS-Gaga-3452 | Gallus gallus | 83.67 | 0.0 | 1458 |
| LLPS-Mea-3046 | Mesocricetus auratus | 83.55 | 0.0 | 1439 |
| LLPS-Scm-0671 | Scophthalmus maximus | 83.49 | 0.0 | 1454 |
| LLPS-Gaa-3168 | Gasterosteus aculeatus | 83.45 | 0.0 | 1464 |
| LLPS-Dar-2720 | Danio rerio | 83.12 | 0.0 | 1461 |
| LLPS-Orl-1223 | Oryzias latipes | 83.1 | 0.0 | 1463 |
| LLPS-Orn-3545 | Oreochromis niloticus | 82.86 | 0.0 | 1464 |
| LLPS-Scf-2519 | Scleropages formosus | 82.38 | 0.0 | 1439 |
| LLPS-Anc-0627 | Anolis carolinensis | 82.21 | 0.0 | 1246 |
| LLPS-Icp-2521 | Ictalurus punctatus | 82.14 | 0.0 | 1447 |
| LLPS-Fia-0558 | Ficedula albicollis | 82.14 | 0.0 | 1439 |
| LLPS-Meg-1751 | Meleagris gallopavo | 81.68 | 0.0 | 1278 |
| LLPS-Tag-2613 | Taeniopygia guttata | 81.64 | 0.0 | 1233 |
| LLPS-Ora-1577 | Ornithorhynchus anatinus | 80.24 | 0.0 | 1248 |
| LLPS-Leo-3425 | Lepisosteus oculatus | 79.64 | 0.0 | 1408 |
| LLPS-Cis-0213 | Ciona savignyi | 73.99 | 0.0 | 804 |
| LLPS-Drm-1549 | Drosophila melanogaster | 73.57 | 0.0 | 1275 |
| LLPS-Cii-0545 | Ciona intestinalis | 72.18 | 0.0 | 1289 |
| LLPS-Cae-1828 | Caenorhabditis elegans | 69.45 | 0.0 | 1220 |
| LLPS-Fuo-0282 | Fusarium oxysporum | 50.81 | 0.0 | 595 |
| LLPS-Cog-1016 | Colletotrichum gloeosporioides | 50.43 | 0.0 | 745 |
| LLPS-Beb-1644 | Beauveria bassiana | 50.25 | 0.0 | 735 |
| LLPS-Coo-0848 | Colletotrichum orbiculare | 50.24 | 0.0 | 727 |
| LLPS-Cogr-1286 | Colletotrichum graminicola | 50.18 | 0.0 | 741 |
| LLPS-Mao-0005 | Magnaporthe oryzae | 50.06 | 0.0 | 750 |
| LLPS-Zyt-1305 | Zymoseptoria tritici | 49.94 | 0.0 | 736 |
| LLPS-Trv-1432 | Trichoderma virens | 49.88 | 0.0 | 742 |
| LLPS-Chr-1001 | Chlamydomonas reinhardtii | 49.82 | 0.0 | 777 |
| LLPS-Pytr-0671 | Pyrenophora triticirepentis | 49.82 | 0.0 | 739 |
| LLPS-Asfu-1288 | Aspergillus fumigatus | 49.76 | 0.0 | 743 |
| LLPS-Pyt-1196 | Pyrenophora teres | 49.7 | 0.0 | 739 |
| LLPS-Lem-0938 | Leptosphaeria maculans | 49.51 | 0.0 | 736 |
| LLPS-Trr-1532 | Trichoderma reesei | 49.45 | 0.0 | 736 |
| LLPS-Sem-1557 | Selaginella moellendorffii | 49.43 | 0.0 | 716 |
| LLPS-Phn-1392 | Phaeosphaeria nodorum | 49.4 | 0.0 | 741 |
| LLPS-Ved-1345 | Verticillium dahliae | 49.39 | 0.0 | 727 |
| LLPS-Hov-1736 | Hordeum vulgare | 49.37 | 2e-148 | 454 |
| LLPS-Asni-0991 | Aspergillus niger | 49.33 | 0.0 | 727 |
| LLPS-Nef-0016 | Neosartorya fischeri | 49.33 | 0.0 | 740 |
| LLPS-Lep-1365 | Leersia perrieri | 49.25 | 0.0 | 716 |
| LLPS-Map-0538 | Magnaporthe poae | 49.16 | 0.0 | 744 |
| LLPS-Gas-0320 | Galdieria sulphuraria | 49.14 | 0.0 | 730 |
| LLPS-Aso-0081 | Aspergillus oryzae | 49.13 | 0.0 | 730 |
| LLPS-Blg-0981 | Blumeria graminis | 49.11 | 0.0 | 728 |
| LLPS-Nec-0242 | Neurospora crassa | 49.1 | 0.0 | 745 |
| LLPS-Asc-1418 | Aspergillus clavatus | 48.98 | 0.0 | 738 |
| LLPS-Yal-1281 | Yarrowia lipolytica | 48.87 | 0.0 | 738 |
| LLPS-Orp-1442 | Oryza punctata | 48.87 | 0.0 | 710 |
| LLPS-Gor-1209 | Gossypium raimondii | 48.84 | 0.0 | 721 |
| LLPS-Vir-0533 | Vigna radiata | 48.74 | 0.0 | 697 |
| LLPS-Orgl-1065 | Oryza glumaepatula | 48.74 | 0.0 | 707 |
| LLPS-Orni-2399 | Oryza nivara | 48.74 | 0.0 | 707 |
| LLPS-Ori-2361 | Oryza indica | 48.74 | 0.0 | 707 |
| LLPS-Org-1746 | Oryza glaberrima | 48.74 | 0.0 | 707 |
| LLPS-Orr-1997 | Oryza rufipogon | 48.74 | 0.0 | 707 |
| LLPS-Ors-2132 | Oryza sativa | 48.74 | 0.0 | 707 |
| LLPS-Asf-0127 | Aspergillus flavus | 48.66 | 0.0 | 734 |
| LLPS-Orb-1764 | Oryza barthii | 48.61 | 0.0 | 707 |
| LLPS-Phv-2582 | Phaseolus vulgaris | 48.61 | 0.0 | 694 |
| LLPS-Tum-1293 | Tuber melanosporum | 48.58 | 0.0 | 732 |
| LLPS-Amt-1748 | Amborella trichopoda | 48.57 | 0.0 | 721 |
| LLPS-Miv-0318 | Microbotryum violaceum | 48.57 | 0.0 | 705 |
| LLPS-Dac-1103 | Daucus carota | 48.51 | 0.0 | 653 |
| LLPS-Fus-1483 | Fusarium solani | 48.51 | 0.0 | 728 |
| LLPS-Gag-1475 | Gaeumannomyces graminis | 48.5 | 0.0 | 725 |
| LLPS-Glm-1231 | Glycine max | 48.48 | 0.0 | 691 |
| LLPS-Coc-0394 | Corchorus capsularis | 48.36 | 0.0 | 716 |
| LLPS-Cus-1559 | Cucumis sativus | 48.27 | 0.0 | 702 |
| LLPS-Met-2615 | Medicago truncatula | 48.23 | 0.0 | 692 |
| LLPS-Dos-1619 | Dothistroma septosporum | 48.22 | 0.0 | 734 |
| LLPS-Asn-0993 | Aspergillus nidulans | 48.2 | 0.0 | 717 |
| LLPS-Asg-1071 | Ashbya gossypii | 48.16 | 0.0 | 729 |
| LLPS-Fuv-1531 | Fusarium verticillioides | 48.04 | 0.0 | 722 |
| LLPS-Cym-0548 | Cyanidioschyzon merolae | 47.96 | 0.0 | 722 |
| LLPS-Pot-1721 | Populus trichocarpa | 47.88 | 0.0 | 714 |
| LLPS-Sac-1302 | Saccharomyces cerevisiae | 47.82 | 0.0 | 731 |
| LLPS-Mae-1154 | Manihot esculenta | 47.81 | 0.0 | 706 |
| LLPS-Thc-2166 | Theobroma cacao | 47.8 | 0.0 | 709 |
| LLPS-Hea-0837 | Helianthus annuus | 47.73 | 0.0 | 711 |
| LLPS-Orm-0799 | Oryza meridionalis | 47.73 | 0.0 | 680 |
| LLPS-Orbr-1894 | Oryza brachyantha | 47.69 | 0.0 | 708 |
| LLPS-Via-0682 | Vigna angularis | 47.63 | 0.0 | 702 |
| LLPS-Ast-0109 | Aspergillus terreus | 47.6 | 0.0 | 699 |
| LLPS-Sob-0621 | Sorghum bicolor | 47.57 | 0.0 | 708 |
| LLPS-Viv-1287 | Vitis vinifera | 47.43 | 0.0 | 706 |
| LLPS-Arl-1608 | Arabidopsis lyrata | 47.24 | 0.0 | 695 |
| LLPS-Brr-0863 | Brassica rapa | 47.18 | 0.0 | 699 |
| LLPS-Sot-0292 | Solanum tuberosum | 47.17 | 0.0 | 739 |
| LLPS-Mua-2260 | Musa acuminata | 47.14 | 0.0 | 704 |
| LLPS-Nia-1509 | Nicotiana attenuata | 47.14 | 0.0 | 697 |
| LLPS-Brn-0680 | Brassica napus | 47.12 | 0.0 | 699 |
| LLPS-Bro-3048 | Brassica oleracea | 47.12 | 0.0 | 696 |
| LLPS-Art-0303 | Arabidopsis thaliana | 47.12 | 0.0 | 697 |
| LLPS-Brd-2152 | Brachypodium distachyon | 46.96 | 0.0 | 701 |
| LLPS-Sei-2324 | Setaria italica | 46.72 | 0.0 | 705 |
| LLPS-Tru-1842 | Triticum urartu | 46.55 | 0.0 | 694 |
| LLPS-Sol-0972 | Solanum lycopersicum | 46.54 | 0.0 | 699 |
| LLPS-Tra-3066 | Triticum aestivum | 46.45 | 0.0 | 695 |
| LLPS-Prp-0047 | Prunus persica | 46.43 | 0.0 | 710 |
| LLPS-Crn-1506 | Cryptococcus neoformans | 46.36 | 0.0 | 681 |
| LLPS-Chc-0705 | Chondrus crispus | 46.16 | 0.0 | 715 |
| LLPS-Zem-1559 | Zea mays | 45.61 | 5e-156 | 488 |
| LLPS-Abg-1105 | Absidia glauca | 45.24 | 0.0 | 654 |