• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gaa-3168

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Alpha-1,4 glucan phosphorylase
Ensembl Gene: ENSGACG00000000827.1
Ensembl Protein: ENSGACP00000001085.1
Organism: Gasterosteus aculeatus
Taxa ID: 69293
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSGACT00000001085.1ENSGACP00000001085.1
UniProtG3N710, G3N710_GASAC

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAKPLTDQDR  RKQISVRGLA  GVENVSDLKT  NFNRHLHFTL  VKDRNVATKR  DYYFALANTV  60
61    RDHLVGRWIR  TQQHYYEKDP  KRVYYLSLEF  YMGRTLQNTM  VNLALENACD  EATYQLGLDM  120
121   EELQDIEEDA  GLGNGGLGRL  AACFLDSMAS  LGLAAYGYGI  RYEFGIFNQK  IVEGWQVEEA  180
181   DDWLRYGNPW  EKARPEYMRP  VHFYGRVEHT  EEGVKWVDTQ  VVLALPYDTP  VPGYRNNIVN  240
241   TMRLWSAKAP  CDFNLKDFNV  GGYIQAVLDR  NLAENISRVL  YPNDNFFEGK  ELRLKQEYFV  300
301   VAATLQDIIR  RFKASKFGST  EFVRLDLASL  PDKVAIQLND  THPAMAIPEL  MRILVDVEKL  360
361   TWVKAWDIVV  RTCAYTNHTV  LPEALERWPV  DLFQNLLPRH  LEIIYEINRR  HLERIATLYP  420
421   GDLDRMRRMS  LIEEGDVKKI  NMAHLCIVGS  HAVNGVARIH  SEIIKDTVFK  DFYEADPEKF  480
481   QNKTNGITPR  RWLVMCNPGL  AEVIAERIGE  DYIRDLDQLK  NLLDFVDDDS  FIRDVAKVKQ  540
541   ENKMKFAAHL  EETYKVKINP  NSMFDVHVKR  IHEYKRQLLN  CLHIITLYNR  IKKEPNKSWT  600
601   PRTVMIGGKA  APGYHTAKMI  IKLITSIGDV  VNNDPMVGDR  LKVIYLENYR  VTLAEKVIPA  660
661   SDLSEQISTA  GTEASGTGNM  KFMLNGALTI  GTMDGANVEM  AEEAGEENLF  IFGMRVPDVK  720
721   AMDIKGYDAM  SYYNRIPELK  QAMDQISGGL  FSPSQPDLFK  DLVSMLMQHD  RFKVFADYEE  780
781   YIKCQERVSE  LYKDPKEWTK  MVIHNIAGCG  KFSSDRTISQ  YAREIWGMEP  SLEKIAAPDD  840
841   PR  842
Nucleotide CDS Sequence (FASTA)
1     ATGGCCAAGC  CTCTGACGGA  CCAGGACAGG  AGGAAGCAGA  TCTCGGTTAG  GGGTCTGGCC  60
61    GGGGTGGAAA  ACGTCTCGGA  CCTGAAAACC  AATTTCAACC  GGCACCTCCA  CTTCACCCTG  120
121   GTCAAAGACC  GAAATGTGGC  CACCAAACGG  GACTACTACT  TCGCCCTAGC  CAACACGGTC  180
181   CGGGACCACC  TGGTGGGACG  TTGGATCCGG  ACACAGCAGC  ACTATTATGA  AAAAGACCCC  240
241   AAACGTGTCT  ACTACCTCTC  CCTGGAGTTC  TACATGGGTC  GCACTCTGCA  GAACACCATG  300
301   GTCAACCTGG  CCCTGGAGAA  CGCCTGCGAT  GAGGCCACAT  ACCAGCTGGG  CCTGGACATG  360
361   GAGGAGCTGC  AGGACATTGA  GGAAGATGCC  GGTCTGGGCA  ACGGTGGTCT  GGGTCGCCTG  420
421   GCTGCTTGCT  TCCTGGACTC  CATGGCCTCT  CTGGGCCTGG  CTGCTTATGG  ATACGGCATC  480
481   CGCTACGAGT  TTGGCATCTT  CAATCAGAAA  ATAGTTGAGG  GCTGGCAGGT  GGAGGAAGCT  540
541   GATGACTGGC  TGCGCTACGG  CAACCCCTGG  GAGAAGGCTC  GCCCCGAGTA  CATGCGTCCG  600
601   GTCCACTTCT  ACGGACGAGT  GGAGCACACA  GAGGAAGGAG  TGAAGTGGGT  TGACACACAA  660
661   GTGGTTCTGG  CTCTTCCTTA  TGACACCCCA  GTTCCCGGTT  ACAGAAACAA  CATTGTCAAC  720
721   ACCATGAGAC  TGTGGTCTGC  TAAGGCCCCC  TGTGACTTTA  ACCTCAAGGA  CTTTAATGTT  780
781   GGGGGCTACA  TTCAAGCCGT  GCTGGACAGA  AACCTGGCTG  AGAACATCTC  CAGGGTCCTC  840
841   TACCCTAACG  ACAATTTCTT  TGAAGGGAAG  GAGCTGCGTC  TGAAGCAGGA  GTACTTTGTC  900
901   GTAGCAGCGA  CTCTTCAGGA  CATCATCCGC  CGATTCAAAG  CCTCCAAGTT  TGGCTCCACT  960
961   GAGTTTGTGC  GACTGGACCT  TGCTTCGCTG  CCGGACAAGG  TGGCCATCCA  GCTGAACGAC  1020
1021  ACCCATCCTG  CTATGGCCAT  CCCCGAGCTG  ATGAGAATCC  TGGTGGACGT  TGAGAAACTC  1080
1081  ACGTGGGTGA  AGGCCTGGGA  CATCGTGGTT  CGTACCTGTG  CCTACACCAA  CCACACCGTC  1140
1141  CTGCCCGAAG  CCCTGGAGCG  TTGGCCCGTC  GACCTCTTCC  AAAACCTGCT  GCCCCGTCAC  1200
1201  CTGGAGATAA  TCTACGAGAT  AAACCGCCGG  CATCTGGAGC  GCATCGCCAC  GCTTTACCCT  1260
1261  GGAGATCTTG  ACCGCATGCG  CCGAATGTCC  CTGATCGAGG  AAGGGGACGT  CAAGAAAATC  1320
1321  AACATGGCCC  ACCTGTGCAT  TGTGGGGTCT  CATGCTGTTA  ACGGAGTGGC  CCGCATCCAC  1380
1381  TCAGAGATCA  TCAAAGACAC  CGTGTTCAAG  GATTTCTACG  AAGCAGACCC  GGAAAAGTTT  1440
1441  CAGAATAAGA  CCAACGGCAT  CACACCCAGG  CGCTGGCTGG  TCATGTGCAA  CCCTGGCCTG  1500
1501  GCTGAGGTCA  TCGCAGAGAG  GATTGGTGAG  GACTACATCC  GTGACCTTGA  CCAGCTGAAG  1560
1561  AACCTTCTGG  ACTTTGTGGA  CGATGACTCC  TTCATTCGGG  ATGTTGCCAA  AGTCAAACAA  1620
1621  GAGAACAAGA  TGAAGTTTGC  TGCCCACCTT  GAGGAGACCT  ACAAGGTGAA  GATCAACCCC  1680
1681  AACTCCATGT  TTGATGTCCA  CGTGAAGAGG  ATCCACGAGT  ACAAAAGGCA  GCTGCTCAAC  1740
1741  TGCCTGCACA  TCATCACGCT  GTACAACCGA  ATCAAGAAGG  AACCGAACAA  GTCATGGACC  1800
1801  CCCAGGACCG  TCATGATTGG  AGGAAAGGCG  GCTCCCGGAT  ACCACACTGC  CAAGATGATC  1860
1861  ATCAAGCTGA  TCACATCGAT  TGGCGACGTC  GTAAATAATG  ACCCCATGGT  GGGAGATCGC  1920
1921  CTCAAAGTCA  TCTACCTGGA  GAACTACCGG  GTCACTCTGG  CTGAAAAGGT  TATTCCTGCA  1980
1981  TCTGACCTGT  CGGAGCAGAT  CTCCACAGCA  GGCACTGAGG  CCTCTGGCAC  CGGGAACATG  2040
2041  AAGTTCATGC  TGAATGGAGC  CCTGACCATC  GGCACAATGG  ATGGAGCCAA  CGTGGAAATG  2100
2101  GCAGAGGAAG  CTGGAGAGGA  GAACCTGTTC  ATCTTCGGCA  TGAGGGTGCC  CGATGTGAAG  2160
2161  GCGATGGACA  TTAAGGGCTA  TGACGCCATG  TCGTACTACA  ACCGTATCCC  AGAGCTGAAG  2220
2221  CAGGCAATGG  ATCAGATATC  TGGAGGCCTC  TTCAGCCCCA  GCCAGCCTGA  CCTCTTCAAA  2280
2281  GACCTCGTCA  GCATGCTGAT  GCAGCACGAT  AGATTTAAGG  TGTTTGCAGA  CTATGAGGAA  2340
2341  TACATCAAAT  GTCAAGAGAG  AGTCAGCGAA  CTCTACAAGG  ACCCTAAAGA  GTGGACCAAG  2400
2401  ATGGTGATTC  ACAACATCGC  CGGCTGTGGC  AAATTCTCCA  GTGACCGCAC  CATCTCCCAG  2460
2461  TATGCCAGGG  AGATCTGGGG  CATGGAGCCC  AGCCTGGAGA  AGATCGCTGC  TCCTGACGAT  2520
2521  CCTCGCTAA  2529

▼ KEYWORD

ID
Family
Carbohydrate metabolism
Complete proteome
Glycosyltransferase
Pyridoxal phosphate
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Glycogen phosphorylase activity
Molecular Function
Linear malto-oligosaccharide phosphorylase activity
Molecular Function
Pyridoxal phosphate binding
Molecular Function
SHG alpha-glucan phosphorylase activity
Biological Process
Carbohydrate metabolic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orn-3545Oreochromis niloticus93.230.01632
LLPS-Orl-1223Oryzias latipes92.870.01624
LLPS-Tar-3858Takifugu rubripes92.50.01609
LLPS-Dar-2720Danio rerio92.040.01605
LLPS-Asm-3284Astyanax mexicanus91.450.01597
LLPS-Pof-0814Poecilia formosa87.50.01542
LLPS-Scf-2519Scleropages formosus86.920.01526
LLPS-Xim-2042Xiphophorus maculatus86.90.01536
LLPS-Ten-0197Tetraodon nigroviridis86.550.01503
LLPS-Scm-0671Scophthalmus maximus86.430.01504
LLPS-Mod-3766Monodelphis domestica84.290.01470
LLPS-Caf-0336Canis familiaris84.170.01471
LLPS-Mup-3137Mustela putorius furo84.050.01468
LLPS-Myl-3998Myotis lucifugus84.050.01469
LLPS-Mum-4530Mus musculus83.930.01470
LLPS-Fud-2770Fukomys damarensis83.810.01464
LLPS-Sus-3405Sus scrofa83.810.01454
LLPS-Ran-2211Rattus norvegicus83.690.01466
LLPS-Fec-0488Felis catus83.690.01463
LLPS-Ova-0928Ovis aries83.570.01466
LLPS-Bot-2636Bos taurus83.570.01467
LLPS-Otg-2499Otolemur garnettii83.530.01473
LLPS-Mal-4709Mandrillus leucophaeus83.450.01464
LLPS-Dio-3494Dipodomys ordii83.450.01466
LLPS-Caj-1868Callithrix jacchus83.450.01464
LLPS-Ict-2498Ictidomys tridecemlineatus83.450.01465
LLPS-Eqc-1387Equus caballus83.450.01461
LLPS-Cap-0935Cavia porcellus83.450.01461
LLPS-Orc-3834Oryctolagus cuniculus83.450.01463
LLPS-Paa-3577Papio anubis83.330.01464
LLPS-Maf-3548Macaca fascicularis83.330.01464
LLPS-Cea-3027Cercocebus atys83.330.01464
LLPS-Poa-3167Pongo abelii83.330.01466
LLPS-Mam-2687Macaca mulatta83.330.01464
LLPS-Man-4055Macaca nemestrina83.330.01464
LLPS-Aim-1024Ailuropoda melanoleuca83.210.01457
LLPS-Aon-2870Aotus nancymaae83.210.01461
LLPS-Rhb-3619Rhinopithecus bieti83.210.01463
LLPS-Pap-3858Pan paniscus83.210.01464
LLPS-Hos-4966Homo sapiens83.210.01464
LLPS-Pat-2921Pan troglodytes83.10.01462
LLPS-Tut-1208Tursiops truncatus82.980.01449
LLPS-Pes-3556Pelodiscus sinensis82.880.01456
LLPS-Loa-3923Loxodonta africana82.620.01455
LLPS-Gog-4002Gorilla gorilla82.140.01459
LLPS-Sah-4019Sarcophilus harrisii81.230.01278
LLPS-Fia-0558Ficedula albicollis80.880.01409
LLPS-Anc-0627Anolis carolinensis80.860.01221
LLPS-Mea-3046Mesocricetus auratus80.760.01388
LLPS-Gaga-3452Gallus gallus80.760.01415
LLPS-Meg-1751Meleagris gallopavo80.440.01263
LLPS-Cas-2685Carlito syrichta80.00.01420
LLPS-Icp-2521Ictalurus punctatus79.930.01422
LLPS-Tag-2613Taeniopygia guttata79.710.01200
LLPS-Leo-3425Lepisosteus oculatus79.550.01400
LLPS-Ora-1577Ornithorhynchus anatinus79.360.01229
LLPS-Drm-1549Drosophila melanogaster72.740.01275
LLPS-Cii-0545Ciona intestinalis71.330.01257
LLPS-Cis-0213Ciona savignyi69.430.0 775
LLPS-Cae-1828Caenorhabditis elegans67.780.01205
LLPS-Pytr-0671Pyrenophora triticirepentis50.610.0 743
LLPS-Pyt-1196Pyrenophora teres50.370.0 740
LLPS-Beb-1644Beauveria bassiana50.310.0 741
LLPS-Fuo-0282Fusarium oxysporum50.080.0 583
LLPS-Lem-0938Leptosphaeria maculans49.810.0 734
LLPS-Mao-0005Magnaporthe oryzae49.570.0 743
LLPS-Cog-1016Colletotrichum gloeosporioides49.570.0 735
LLPS-Blg-0981Blumeria graminis49.390.0 731
LLPS-Coo-0848Colletotrichum orbiculare49.390.0 713
LLPS-Yal-1281Yarrowia lipolytica49.330.0 739
LLPS-Trv-1432Trichoderma virens49.270.0 737
LLPS-Gas-0320Galdieria sulphuraria49.260.0 741
LLPS-Zyt-1305Zymoseptoria tritici49.070.0 728
LLPS-Cogr-1286Colletotrichum graminicola49.070.0 725
LLPS-Ved-1345Verticillium dahliae49.030.0 726
LLPS-Chr-1001Chlamydomonas reinhardtii49.020.0 751
LLPS-Fuv-1531Fusarium verticillioides48.950.0 715
LLPS-Phn-1392Phaeosphaeria nodorum48.850.0 737
LLPS-Fus-1483Fusarium solani48.830.0 719
LLPS-Gag-1475Gaeumannomyces graminis48.780.0 726
LLPS-Nef-0016Neosartorya fischeri48.780.0 735
LLPS-Tum-1293Tuber melanosporum48.770.0 726
LLPS-Nec-0242Neurospora crassa48.740.0 748
LLPS-Lep-1365Leersia perrieri48.680.0 710
LLPS-Asfu-1288Aspergillus fumigatus48.660.0 734
LLPS-Asc-1418Aspergillus clavatus48.560.0 737
LLPS-Orp-1442Oryza punctata48.550.0 707
LLPS-Asn-0993Aspergillus nidulans48.540.0 728
LLPS-Map-0538Magnaporthe poae48.50.0 739
LLPS-Mae-1154Manihot esculenta48.480.0 697
LLPS-Aso-0081Aspergillus oryzae48.450.0 729
LLPS-Orgl-1065Oryza glumaepatula48.420.0 704
LLPS-Asni-0991Aspergillus niger48.420.0 723
LLPS-Orni-2399Oryza nivara48.420.0 705
LLPS-Ori-2361Oryza indica48.420.0 705
LLPS-Org-1746Oryza glaberrima48.420.0 705
LLPS-Orr-1997Oryza rufipogon48.420.0 704
LLPS-Ors-2132Oryza sativa48.420.0 704
LLPS-Dos-1619Dothistroma septosporum48.40.0 725
LLPS-Chc-0705Chondrus crispus48.320.0 732
LLPS-Orb-1764Oryza barthii48.30.0 705
LLPS-Sac-1302Saccharomyces cerevisiae48.230.0 726
LLPS-Amt-1748Amborella trichopoda48.170.0 716
LLPS-Dac-1103Daucus carota48.10.0 634
LLPS-Orbr-1894Oryza brachyantha48.050.0 703
LLPS-Coc-0394Corchorus capsularis47.980.0 712
LLPS-Trr-1532Trichoderma reesei47.980.0 733
LLPS-Miv-0318Microbotryum violaceum47.950.0 702
LLPS-Asf-0127Aspergillus flavus47.870.0 732
LLPS-Gor-1209Gossypium raimondii47.740.0 713
LLPS-Brd-2152Brachypodium distachyon47.470.0 702
LLPS-Brr-0863Brassica rapa47.460.0 691
LLPS-Vir-0533Vigna radiata47.40.0 689
LLPS-Bro-3048Brassica oleracea47.40.0 688
LLPS-Thc-2166Theobroma cacao47.370.0 711
LLPS-Arl-1608Arabidopsis lyrata47.340.0 684
LLPS-Sem-1557Selaginella moellendorffii47.340.0 692
LLPS-Brn-0680Brassica napus47.340.0 687
LLPS-Tru-1842Triticum urartu47.340.0 692
LLPS-Viv-1287Vitis vinifera47.310.0 704
LLPS-Orm-0799Oryza meridionalis47.290.0 678
LLPS-Glm-1231Glycine max47.270.0 683
LLPS-Hov-1736Hordeum vulgare47.262e-142 438
LLPS-Sol-0972Solanum lycopersicum47.250.0 704
LLPS-Pot-1721Populus trichocarpa47.210.0 699
LLPS-Met-2615Medicago truncatula47.140.0 686
LLPS-Sot-0292Solanum tuberosum47.040.0 723
LLPS-Crn-1506Cryptococcus neoformans47.020.0 677
LLPS-Asg-1071Ashbya gossypii46.640.0 711
LLPS-Nia-1509Nicotiana attenuata46.580.0 694
LLPS-Mua-2260Musa acuminata46.540.0 697
LLPS-Cym-0548Cyanidioschyzon merolae46.530.0 717
LLPS-Sob-0621Sorghum bicolor46.530.0 702
LLPS-Hea-0837Helianthus annuus46.50.0 700
LLPS-Cus-1559Cucumis sativus46.470.0 694
LLPS-Sei-2324Setaria italica46.350.0 701
LLPS-Via-0682Vigna angularis46.330.0 692
LLPS-Tra-3066Triticum aestivum46.080.0 694
LLPS-Phv-2582Phaseolus vulgaris45.970.0 686
LLPS-Ast-0109Aspergillus terreus45.750.0 687
LLPS-Prp-0047Prunus persica45.70.0 711
LLPS-Art-0303Arabidopsis thaliana45.440.0 684
LLPS-Zem-1559Zea mays45.277e-155 484
LLPS-Abg-1105Absidia glauca44.150.0 647