• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mal-0661
DHODH

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Dihydroorotate dehydrogenase (quinone), mitochondrial
Gene Name: DHODH
Ensembl Gene: ENSMLEG00000031692.1
Ensembl Protein: ENSMLEP00000015056.1
Organism: Mandrillus leucophaeus
Taxa ID: 9568
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAWRHLKKRA  QDAVVILGGG  GLLFASYLMA  TGDERFYAEH  LMPALQGLLD  PESAHRLAVR  60
61    FTSLGLLPRA  RFQDSDMLEV  RVLGHKFRNP  VGIAAGFDKH  GEAVDGLYKM  GFGFVEIGSV  120
121   TPKPQEGNPR  PRVFRLPEDQ  AVINRYGFNS  HGLSVVEHRL  RARQQKQAKL  TEDGLPLGVN  180
181   LGKNKTSVDA  AEDYAEGVRV  LGPLADYLVV  NVSSPNTAGL  RSLQGKAELR  RLLTKVLQER  240
241   DGLQGAHRPA  VLVKIAPDLT  AQDKEDIASV  VKELGIDGLI  VTNTTVSRPA  GLQGALRSET  300
301   GGLSGKPLRD  LSTQTIREMY  ALTQGRVPII  GVGGVSSGQD  ALEKIRAGAS  LVQLYTALTF  360
361   WGPPVVGRVK  RELEALLKEQ  GFGRVTDAIG  ADHRR  395
Nucleotide CDS Sequence (FASTA)
1     ATGGCGTGGA  GACACCTGAA  AAAGCGGGCC  CAGGATGCTG  TGGTCATCCT  GGGGGGCGGA  60
61    GGACTTCTCT  TCGCCTCCTA  CCTGATGGCC  ACGGGAGATG  AGCGTTTCTA  TGCTGAACAC  120
121   CTGATGCCAG  CTCTGCAGGG  GCTGCTGGAT  CCGGAGTCAG  CCCACAGACT  GGCCGTTCGC  180
181   TTCACCTCCC  TGGGGCTCCT  TCCACGGGCC  AGATTTCAAG  ACTCTGACAT  GCTGGAAGTG  240
241   AGAGTTCTGG  GCCATAAATT  CCGAAATCCA  GTAGGAATTG  CTGCAGGATT  TGACAAGCAT  300
301   GGGGAAGCCG  TGGACGGACT  TTATAAGATG  GGCTTTGGTT  TTGTTGAGAT  AGGAAGTGTG  360
361   ACTCCAAAAC  CTCAGGAAGG  AAACCCCAGA  CCCAGAGTCT  TCCGTCTCCC  CGAGGACCAA  420
421   GCTGTCATTA  ACAGGTATGG  GTTTAACAGT  CACGGGCTTT  CGGTGGTGGA  ACACAGGTTA  480
481   CGCGCCAGAC  AGCAGAAGCA  GGCCAAGCTC  ACAGAAGATG  GACTGCCGCT  GGGGGTCAAC  540
541   TTGGGGAAGA  ACAAGACCTC  AGTGGACGCC  GCGGAGGACT  ACGCAGAAGG  GGTGCGCGTG  600
601   CTGGGCCCGC  TGGCCGACTA  CCTGGTGGTC  AATGTGTCCA  GCCCCAACAC  GGCCGGGCTG  660
661   CGGAGCCTTC  AAGGAAAGGC  TGAGCTGCGC  CGCCTGCTGA  CCAAGGTGCT  GCAGGAGAGG  720
721   GACGGCTTAC  AGGGAGCGCA  CAGGCCGGCA  GTGCTGGTGA  AGATCGCTCC  TGACCTCACC  780
781   GCCCAGGACA  AGGAGGACAT  TGCCAGTGTG  GTCAAAGAGT  TGGGCATTGA  TGGGCTGATT  840
841   GTTACGAACA  CCACCGTGAG  TCGCCCTGCT  GGCCTCCAGG  GTGCCCTGCG  CTCTGAAACA  900
901   GGAGGGCTGA  GTGGGAAGCC  CCTCCGGGAT  TTATCAACTC  AAACCATTCG  GGAGATGTAT  960
961   GCACTCACCC  AAGGCCGAGT  TCCCATAATT  GGGGTTGGTG  GCGTGAGCAG  CGGGCAGGAC  1020
1021  GCGCTGGAGA  AGATCCGGGC  AGGGGCCTCC  CTGGTGCAGC  TGTACACGGC  CCTCACCTTC  1080
1081  TGGGGACCAC  CCGTTGTGGG  CAGAGTTAAG  CGGGAGCTGG  AGGCCCTTCT  GAAAGAGCAG  1140
1141  GGCTTTGGCA  GAGTCACAGA  TGCCATTGGA  GCAGATCATC  GGAGGTGA  1188

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mam-1597Macaca mulatta100.00.0 768
LLPS-Cea-4118Cercocebus atys100.00.0 768
LLPS-Man-3025Macaca nemestrina99.750.0 766
LLPS-Maf-3684Macaca fascicularis99.490.0 763
LLPS-Paa-3267Papio anubis99.490.0 764
LLPS-Chs-3215Chlorocebus sabaeus99.240.0 764
LLPS-Rhb-1858Rhinopithecus bieti99.180.0 707
LLPS-Pap-4156Pan paniscus98.230.0 756
LLPS-Hos-3455Homo sapiens97.970.0 753
LLPS-Pat-2619Pan troglodytes97.970.0 756
LLPS-Poa-4394Pongo abelii97.820.0 699
LLPS-Gog-1592Gorilla gorilla97.720.0 757
LLPS-Nol-3259Nomascus leucogenys97.470.0 753
LLPS-Aon-1247Aotus nancymaae97.220.0 749
LLPS-Caj-1181Callithrix jacchus96.390.0 726
LLPS-Eqc-0481Equus caballus93.830.0 713
LLPS-Tut-1747Tursiops truncatus93.420.0 719
LLPS-Otg-4249Otolemur garnettii92.910.0 703
LLPS-Sus-4219Sus scrofa92.910.0 717
LLPS-Fec-4448Felis catus92.660.0 710
LLPS-Urm-1649Ursus maritimus92.410.0 706
LLPS-Bot-1435Bos taurus92.410.0 709
LLPS-Mup-4288Mustela putorius furo92.150.0 707
LLPS-Aim-3739Ailuropoda melanoleuca92.050.0 691
LLPS-Myl-2424Myotis lucifugus91.90.0 691
LLPS-Orc-0236Oryctolagus cuniculus91.650.0 717
LLPS-Caf-1300Canis familiaris91.280.0 689
LLPS-Ict-1948Ictidomys tridecemlineatus90.890.0 698
LLPS-Dio-4037Dipodomys ordii90.610.0 702
LLPS-Ova-3605Ovis aries90.380.0 686
LLPS-Cas-0422Carlito syrichta89.242e-126 371
LLPS-Mea-2645Mesocricetus auratus89.110.0 689
LLPS-Ran-4005Rattus norvegicus89.110.0 686
LLPS-Loa-0486Loxodonta africana88.660.0 689
LLPS-Mum-4641Mus musculus88.350.0 687
LLPS-Cap-1538Cavia porcellus87.850.0 654
LLPS-Ora-0295Ornithorhynchus anatinus86.383e-179 509
LLPS-Fud-4070Fukomys damarensis86.330.0 639
LLPS-Mod-1526Monodelphis domestica81.280.0 638
LLPS-Anp-2324Anas platyrhynchos79.571e-143 417
LLPS-Sah-2485Sarcophilus harrisii79.240.0 627
LLPS-Meg-0437Meleagris gallopavo78.233e-169 483
LLPS-Anc-0615Anolis carolinensis76.131e-102 310
LLPS-Gaga-1017Gallus gallus75.142e-173 497
LLPS-Fia-2252Ficedula albicollis74.078e-174 498
LLPS-Leo-3767Lepisosteus oculatus72.340.0 554
LLPS-Orl-1197Oryzias latipes70.770.0 551
LLPS-Gaa-3431Gasterosteus aculeatus70.590.0 542
LLPS-Pof-2999Poecilia formosa70.560.0 548
LLPS-Xim-2381Xiphophorus maculatus70.560.0 548
LLPS-Icp-0485Ictalurus punctatus70.510.0 539
LLPS-Scm-3048Scophthalmus maximus70.260.0 545
LLPS-Tar-0425Takifugu rubripes70.260.0 547
LLPS-Ten-1659Tetraodon nigroviridis69.740.0 547
LLPS-Scf-1571Scleropages formosus69.540.0 541
LLPS-Asm-0702Astyanax mexicanus68.460.0 528
LLPS-Dar-1219Danio rerio68.020.0 530
LLPS-Xet-1745Xenopus tropicalis68.020.0 516
LLPS-Mel-0098Melampsora laricipopulina56.411e-35 142
LLPS-Osl-0503Ostreococcus lucimarinus53.421e-112 342
LLPS-Cii-0884Ciona intestinalis53.48e-132 391
LLPS-Chr-0392Chlamydomonas reinhardtii53.122e-109 334
LLPS-Cis-0581Ciona savignyi51.724e-133 395
LLPS-Cae-1982Caenorhabditis elegans50.777e-121 363
LLPS-Gas-0530Galdieria sulphuraria49.627e-112 340
LLPS-Drm-1716Drosophila melanogaster49.215e-111 338
LLPS-Scp-0511Schizosaccharomyces pombe47.232e-96 302
LLPS-Asg-1354Ashbya gossypii45.791e-86 277
LLPS-Cym-0869Cyanidioschyzon merolae45.772e-97 304
LLPS-Usm-0266Ustilago maydis45.573e-93 300
LLPS-Yal-1490Yarrowia lipolytica45.01e-91 290
LLPS-Scc-0750Schizosaccharomyces cryophilus44.742e-89 284
LLPS-Spr-0911Sporisorium reilianum43.872e-93 301
LLPS-Miv-0843Microbotryum violaceum43.321e-95 312
LLPS-Scj-1496Schizosaccharomyces japonicus41.456e-80 259
LLPS-Abg-1505Absidia glauca28.343e-1065.1