• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Maf-4585
EGM_19488

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pyruvate kinase
Gene Name: EGM_19488
Ensembl Gene: ENSMFAG00000034196.1
Ensembl Protein: ENSMFAP00000037893.1
Organism: Macaca fascicularis
Taxa ID: 9541
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSIQENIPSP  RRWSWVSKSQ  RDLAKSILIG  APGGPAGYLR  RASVAQLTQE  LGTAFFQQQQ  60
61    LPAAMADTFL  EHLCLLDIDS  EPVAARSTSI  IATIGPASRS  VERLKEMIKA  GMNIARLNFS  120
121   HGSHEYHAES  IANVREAVES  FAASPLSYRP  VAIALDTKGP  EIRTGILQGG  PESEVELVKG  180
181   SQVLVTVDPA  FRTRGNANTV  WVDYPNIVGV  VPVGGRIYID  DGLISLVVQK  IGPEGLVTQV  240
241   ENGGVLASRK  GVNLPGAQVD  LPGLSEQDVR  DLRFGVEHGV  DIVFASFVRK  ASDVAAVRAA  300
301   LGPEGQGIKI  ISKIENHEGV  KRFDEILEVS  DGIMVARGDL  GIEIPAEKVF  LAQKMMIGRC  360
361   NLAGKPVVCA  TQMLESMITK  PRPTRAETSD  VANAVLDGAD  CIMLSGETAK  GNFPVEAVKM  420
421   QHAIAREAEA  AVYHRQLFEE  LRRAAPLSRD  PTEVIAIGAV  EAAFKCCAAA  IIVLTTTGRS  480
481   AQLLSQYRPR  AAVIAVTRSA  QAARQVHLCR  GVFPLLYREP  PEAIWADDVD  RRVQFGIESG  540
541   KLRGFLRVGD  LVIVVTGWRP  GSGYTNIMRV  LSIS  574
Nucleotide CDS Sequence (FASTA)
1     ATGTCGATCC  AGGAGAACAT  ACCATCCCCG  CGGCGCTGGT  CATGGGTCTC  TAAGTCCCAA  60
61    AGAGACTTAG  CGAAGTCCAT  CCTGATTGGG  GCTCCAGGAG  GGCCAGCGGG  GTATCTTCGG  120
121   CGGGCTAGTG  TGGCCCAACT  GACCCAGGAG  CTGGGCACTG  CCTTCTTCCA  GCAGCAGCAG  180
181   CTGCCAGCTG  CTATGGCAGA  CACCTTCCTG  GAGCACCTCT  GCCTACTGGA  CATTGACTCC  240
241   GAGCCCGTGG  CTGCTCGCAG  TACCAGCATC  ATTGCCACCA  TCGGGCCGGC  ATCTCGCTCC  300
301   GTGGAGCGCC  TCAAGGAGAT  GATCAAGGCC  GGGATGAACA  TTGCGCGACT  CAATTTCTCC  360
361   CACGGCTCCC  ACGAGTACCA  CGCTGAGTCC  ATCGCCAACG  TCCGGGAGGC  GGTGGAGAGC  420
421   TTTGCAGCTT  CCCCGCTCAG  CTACCGGCCC  GTGGCCATCG  CCCTGGACAC  CAAGGGACCG  480
481   GAGATCCGCA  CTGGGATCCT  GCAGGGGGGT  CCGGAGTCGG  AAGTGGAGCT  GGTGAAGGGC  540
541   TCCCAGGTGC  TGGTGACTGT  GGACCCCGCG  TTTCGGACGC  GGGGGAACGC  GAACACCGTG  600
601   TGGGTGGACT  ACCCCAATAT  TGTCGGGGTC  GTGCCTGTGG  GGGGCCGCAT  CTACATTGAC  660
661   GACGGGCTCA  TCTCCCTAGT  GGTCCAGAAA  ATCGGCCCAG  AGGGACTGGT  GACCCAAGTG  720
721   GAGAACGGTG  GCGTCCTGGC  CAGCCGTAAG  GGCGTGAACT  TGCCGGGGGC  CCAGGTGGAC  780
781   TTGCCCGGGC  TGTCCGAGCA  GGACGTCCGG  GACCTGCGCT  TCGGGGTGGA  GCATGGAGTG  840
841   GACATCGTGT  TTGCCTCCTT  TGTGCGGAAA  GCCAGCGATG  TGGCTGCTGT  CAGGGCTGCT  900
901   CTGGGGCCGG  AAGGACAGGG  CATCAAGATC  ATCAGCAAAA  TTGAGAACCA  CGAAGGCGTG  960
961   AAGAGGTTTG  ATGAAATCCT  GGAGGTGAGC  GACGGTATCA  TGGTGGCACG  GGGGGACCTA  1020
1021  GGCATCGAGA  TTCCAGCAGA  GAAGGTTTTC  CTGGCTCAGA  AGATGATGAT  TGGGCGCTGC  1080
1081  AACTTGGCGG  GCAAGCCTGT  TGTCTGTGCT  ACACAGATGC  TGGAGAGCAT  GATTACCAAG  1140
1141  CCCCGGCCAA  CGAGGGCAGA  AACAAGCGAT  GTGGCCAATG  CTGTGCTAGA  TGGGGCCGAC  1200
1201  TGCATCATGC  TGTCAGGGGA  GACTGCCAAA  GGCAACTTCC  CTGTGGAAGC  CGTGAAGATG  1260
1261  CAGCATGCGA  TTGCCCGGGA  GGCAGAGGCT  GCAGTGTACC  ACCGGCAGCT  GTTTGAGGAG  1320
1321  CTACGTCGGG  CAGCGCCACT  GAGCCGTGAT  CCCACTGAGG  TCATCGCCAT  TGGCGCCGTG  1380
1381  GAGGCTGCCT  TCAAGTGCTG  TGCTGCTGCC  ATCATCGTAC  TGACCACAAC  TGGCCGCTCA  1440
1441  GCCCAGCTTC  TGTCTCAGTA  CCGACCTCGG  GCAGCAGTCA  TTGCTGTCAC  CCGCTCTGCC  1500
1501  CAAGCTGCCC  GCCAGGTCCA  CTTATGCCGA  GGAGTCTTCC  CCTTGCTTTA  CCGTGAACCT  1560
1561  CCAGAAGCCA  TCTGGGCAGA  TGACGTAGAT  CGCCGGGTGC  AATTTGGCAT  TGAAAGTGGA  1620
1621  AAGCTCCGTG  GCTTCCTCCG  TGTTGGAGAC  CTGGTGATTG  TGGTGACAGG  CTGGCGACCT  1680
1681  GGCTCCGGCT  ACACCAACAT  CATGCGGGTG  CTGAGCATAT  CCTGA  1725

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mam-3518Macaca mulatta100.00.01059
LLPS-Man-2235Macaca nemestrina99.820.01058
LLPS-Paa-2046Papio anubis99.480.01122
LLPS-Cea-4739Cercocebus atys99.480.01122
LLPS-Chs-4469Chlorocebus sabaeus99.170.0 931
LLPS-Rhb-0788Rhinopithecus bieti98.610.01092
LLPS-Gog-1278Gorilla gorilla98.260.01103
LLPS-Hos-1756Homo sapiens98.080.01101
LLPS-Pap-4355Pan paniscus97.910.01100
LLPS-Pat-0093Pan troglodytes97.740.01098
LLPS-Poa-4096Pongo abelii97.640.0 718
LLPS-Caj-4121Callithrix jacchus97.040.01096
LLPS-Loa-2052Loxodonta africana94.080.01072
LLPS-Ict-3889Ictidomys tridecemlineatus93.940.01040
LLPS-Orc-0670Oryctolagus cuniculus93.410.01063
LLPS-Cap-4512Cavia porcellus93.350.01003
LLPS-Sus-1016Sus scrofa93.310.0 930
LLPS-Fud-3445Fukomys damarensis92.240.0 990
LLPS-Myl-0321Myotis lucifugus92.190.01033
LLPS-Aon-4502Aotus nancymaae92.150.01019
LLPS-Caf-1866Canis familiaris91.990.01036
LLPS-Eqc-4453Equus caballus91.990.01021
LLPS-Bot-3828Bos taurus91.890.0 941
LLPS-Mea-0647Mesocricetus auratus91.80.01040
LLPS-Dio-3688Dipodomys ordii91.580.01008
LLPS-Aim-1322Ailuropoda melanoleuca91.460.01031
LLPS-Mum-3304Mus musculus91.110.01033
LLPS-Tut-2353Tursiops truncatus91.090.01057
LLPS-Ran-3620Rattus norvegicus90.770.01032
LLPS-Mup-1271Mustela putorius furo90.770.01027
LLPS-Otg-3549Otolemur garnettii90.420.01020
LLPS-Sah-0626Sarcophilus harrisii90.00.01001
LLPS-Mal-2030Mandrillus leucophaeus87.870.0 946
LLPS-Fec-0144Felis catus87.80.0 974
LLPS-Ova-0929Ovis aries86.850.01008
LLPS-Nol-3932Nomascus leucogenys85.420.0 880
LLPS-Mod-3101Monodelphis domestica84.550.0 921
LLPS-Lac-4092Latimeria chalumnae76.330.0 797
LLPS-Xet-0727Xenopus tropicalis75.470.0 791
LLPS-Ora-0940Ornithorhynchus anatinus74.66e-122 367
LLPS-Leo-1579Lepisosteus oculatus73.140.0 790
LLPS-Tag-0182Taeniopygia guttata71.810.0 749
LLPS-Anp-1067Anas platyrhynchos71.050.0 742
LLPS-Icp-0476Ictalurus punctatus70.990.0 759
LLPS-Anc-0061Anolis carolinensis70.770.0 756
LLPS-Pes-2692Pelodiscus sinensis70.770.0 740
LLPS-Cas-2320Carlito syrichta70.620.0 754
LLPS-Asm-1232Astyanax mexicanus70.550.0 738
LLPS-Scf-1515Scleropages formosus70.420.0 764
LLPS-Tar-0743Takifugu rubripes70.320.0 765
LLPS-Orl-1831Oryzias latipes70.040.0 766
LLPS-Scm-0244Scophthalmus maximus69.920.0 761
LLPS-Gaga-2684Gallus gallus69.90.0 755
LLPS-Pof-1429Poecilia formosa69.890.0 767
LLPS-Xim-0138Xiphophorus maculatus69.890.0 764
LLPS-Meg-0347Meleagris gallopavo69.710.0 754
LLPS-Dar-1153Danio rerio69.330.0 760
LLPS-Gaa-3189Gasterosteus aculeatus69.330.0 763
LLPS-Urm-1530Ursus maritimus69.270.0 721
LLPS-Orn-2744Oreochromis niloticus68.980.0 762
LLPS-Fia-2080Ficedula albicollis68.960.0 764
LLPS-Ten-3004Tetraodon nigroviridis68.610.0 755
LLPS-Cii-0258Ciona intestinalis65.350.0 692
LLPS-Cis-1169Ciona savignyi64.110.0 696
LLPS-Drm-0086Drosophila melanogaster59.530.0 603
LLPS-Put-0765Puccinia triticina56.362e-129 390
LLPS-Cae-0858Caenorhabditis elegans55.580.0 592
LLPS-Crn-1265Cryptococcus neoformans55.197e-177 520
LLPS-Asfu-0299Aspergillus fumigatus54.184e-175 513
LLPS-Scc-0718Schizosaccharomyces cryophilus53.867e-171 502
LLPS-Scj-0721Schizosaccharomyces japonicus53.472e-171 504
LLPS-Asc-0750Aspergillus clavatus53.163e-173 509
LLPS-Nef-0570Neosartorya fischeri53.158e-175 513
LLPS-Miv-1002Microbotryum violaceum53.147e-171 503
LLPS-Asn-0064Aspergillus nidulans52.953e-172 506
LLPS-Asf-1349Aspergillus flavus52.758e-173 508
LLPS-Aso-1442Aspergillus oryzae52.758e-173 508
LLPS-Scp-1444Schizosaccharomyces pombe52.62e-169 498
LLPS-Asni-0078Aspergillus niger52.555e-172 506
LLPS-Pug-1290Puccinia graminis52.541e-168 498
LLPS-Usm-0900Ustilago maydis52.446e-171 503
LLPS-Spr-0346Sporisorium reilianum52.449e-171 503
LLPS-Yal-1059Yarrowia lipolytica52.262e-176 516
LLPS-Trv-0874Trichoderma virens52.145e-161 478
LLPS-Gas-0532Galdieria sulphuraria51.91e-145 437
LLPS-Dos-0593Dothistroma septosporum51.727e-170 500
LLPS-Ast-0020Aspergillus terreus51.633e-173 509
LLPS-Abg-0614Absidia glauca51.618e-167 492
LLPS-Zyt-0601Zymoseptoria tritici51.522e-167 494
LLPS-Phn-1023Phaeosphaeria nodorum51.373e-171 504
LLPS-Scs-0235Sclerotinia sclerotiorum51.228e-156 464
LLPS-Mel-0328Melampsora laricipopulina51.219e-164 484
LLPS-Pytr-0392Pyrenophora triticirepentis50.985e-168 495
LLPS-Pyt-0104Pyrenophora teres50.981e-167 494
LLPS-Asg-1230Ashbya gossypii50.511e-160 476
LLPS-Fus-0477Fusarium solani50.411e-155 464
LLPS-Lem-1431Leptosphaeria maculans50.395e-167 494
LLPS-Kop-1219Komagataella pastoris50.33e-165 488
LLPS-Tum-0618Tuber melanosporum50.12e-164 485
LLPS-Sac-1298Saccharomyces cerevisiae50.02e-161 478
LLPS-Beb-0422Beauveria bassiana49.97e-158 470
LLPS-Chc-0234Chondrus crispus49.93e-142 428
LLPS-Ved-0369Verticillium dahliae49.86e-151 452
LLPS-Coo-1281Colletotrichum orbiculare49.83e-152 455
LLPS-Mao-1105Magnaporthe oryzae49.692e-153 458
LLPS-Cogr-1124Colletotrichum graminicola49.66e-153 457
LLPS-Blg-0746Blumeria graminis49.511e-152 456
LLPS-Fuo-0350Fusarium oxysporum49.394e-155 462
LLPS-Fuv-0200Fusarium verticillioides49.397e-155 462
LLPS-Map-0615Magnaporthe poae49.212e-153 458
LLPS-Gag-1300Gaeumannomyces graminis49.218e-155 462
LLPS-Trr-0453Trichoderma reesei49.065e-157 468
LLPS-Nec-0013Neurospora crassa47.324e-152 454
LLPS-Chr-0577Chlamydomonas reinhardtii47.115e-132 402
LLPS-Cym-0263Cyanidioschyzon merolae46.764e-137 416
LLPS-Brn-0625Brassica napus46.713e-128 392
LLPS-Orbr-0544Oryza brachyantha46.493e-127 390
LLPS-Cog-0124Colletotrichum gloeosporioides46.158e-135 409
LLPS-Org-0923Oryza glaberrima46.072e-127 390
LLPS-Orm-1168Oryza meridionalis46.072e-127 390
LLPS-Ors-0201Oryza sativa46.072e-127 390
LLPS-Orgl-2045Oryza glumaepatula46.072e-127 390
LLPS-Hea-1225Helianthus annuus46.076e-129 394
LLPS-Orni-1501Oryza nivara46.072e-127 390
LLPS-Orb-0574Oryza barthii46.072e-127 390
LLPS-Ori-0265Oryza indica46.072e-127 390
LLPS-Orr-0940Oryza rufipogon45.667e-127 390
LLPS-Brd-0367Brachypodium distachyon45.662e-126 388
LLPS-Bro-2128Brassica oleracea45.456e-126 387
LLPS-Coc-1481Corchorus capsularis45.454e-129 395
LLPS-Brr-2113Brassica rapa45.452e-124 383
LLPS-Cus-1872Cucumis sativus45.452e-129 396
LLPS-Tra-3058Triticum aestivum45.455e-128 392
LLPS-Zem-1513Zea mays45.253e-126 391
LLPS-Gor-0926Gossypium raimondii45.253e-125 385
LLPS-Met-0327Medicago truncatula45.252e-127 390
LLPS-Sei-2029Setaria italica45.251e-125 386
LLPS-Arl-1133Arabidopsis lyrata45.251e-128 394
LLPS-Dac-1406Daucus carota45.251e-129 396
LLPS-Sob-0214Sorghum bicolor45.097e-127 389
LLPS-Lep-1500Leersia perrieri45.072e-125 385
LLPS-Amt-0957Amborella trichopoda45.046e-126 387
LLPS-Art-2542Arabidopsis thaliana45.045e-128 392
LLPS-Thc-0692Theobroma cacao45.042e-127 391
LLPS-Pot-1588Populus trichocarpa44.978e-130 397
LLPS-Orp-1430Oryza punctata44.876e-128 392
LLPS-Prp-0157Prunus persica44.835e-127 390
LLPS-Nia-1028Nicotiana attenuata44.837e-127 389
LLPS-Vir-1424Vigna radiata44.639e-126 386
LLPS-Via-1067Vigna angularis44.631e-125 386
LLPS-Sot-1500Solanum tuberosum44.632e-124 383
LLPS-Phv-0505Phaseolus vulgaris44.422e-125 385
LLPS-Glm-1524Glycine max44.427e-126 387
LLPS-Sol-0446Solanum lycopersicum44.422e-124 383
LLPS-Tru-1578Triticum urartu44.053e-122 377
LLPS-Viv-1106Vitis vinifera44.019e-122 376
LLPS-Mua-1633Musa acuminata43.743e-125 385
LLPS-Sem-1277Selaginella moellendorffii43.451e-125 386
LLPS-Mae-2279Manihot esculenta43.432e-124 382
LLPS-Hov-0157Hordeum vulgare43.392e-121 375
LLPS-Php-2443Physcomitrella patens43.258e-125 384