LLPS-Loa-a045
FUT8
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Alpha-(1,6)-fucosyltransferase |
| Gene Name: | FUT8 |
| Ensembl Gene: | ENSLAFG00000014315.2 |
| Ensembl Protein: | ENSLAFP00000011992.2 |
| Organism: | Loxodonta africana |
| Taxa ID: | 9785 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLAFT00000014318.2 | ENSLAFP00000011992.2 |
| UniProt | G3TD08, G3TD08_LOXAF | |
| RefSeq | XM_003408717.2, XM_010588693.1, XM_010588694.1, XM_010588695.1 | XP_003408765.1, XP_010586995.1, XP_010586996.1, XP_010586997.1 |
| Entrez | 100657054 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MRPWTGSWRW IMLILFAWGT LLFYIGGHLV RDNDHPDHSS RELSKILAKL ERLKQQNEDL 60 61 RRMAESLRIP EGPIDQGPAA GRVRALEEQL IKAKEQIENY KKQTRNGLGK DHEILRRRIE 120 121 NGAKELWFYL QSELKKLKNL EGSELQRHVD EFLSDLGHHE RSIMTDLYYL SQTDGAGDWR 180 181 EKEAKDLTEL VQRRITYLQN PKDCSKAKKL VCNINKGCGY GCQLHHVVYC FMIAYGTQRT 240 241 LILESQNWRY ATGGWETVFR PVSETCTDRS GISTGHWSGE VKDKNVQVVE LPIVDSLHPR 300 301 PPYLPLAVPE DLADRLVRVH GDPAVWWVSQ FVKYLIRPQP WLEKEIEEAT KKLGFQHPVV 360 361 GVHVRRTDKV GTEAAFHPIE EYMVHVEEHF QLLARRMQVD KKRVYLATDD PSLLKEAKTK 420 421 YPNYEFISDN SISWSAGLHN RYTENSLRGV ILDIHFLSQA DFLVCTFSSQ VCRVAYEIMQ 480 481 TLHPDASANF HSLDDIYYFG GQNAHNQIAI YPHQPRTADE IPMEPGDIIG VAGNHWDGYS 540 541 KGVNRKLGRT GLYPSYKVQE KIETVKYPTY PEADK 575 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCGGCCAT GGACTGGTTC CTGGCGTTGG ATTATGCTCA TTCTCTTTGC CTGGGGGACC 60 61 TTGCTGTTTT ATATAGGTGG TCACTTGGTA CGAGATAATG ACCACCCTGA TCACTCTAGC 120 121 CGAGAACTGT CCAAGATTCT GGCAAAGCTT GAACGCTTAA AACAGCAGAA TGAAGACTTG 180 181 AGGCGAATGG CTGAGTCTCT TCGGATTCCA GAAGGCCCCA TTGATCAGGG GCCGGCTGCA 240 241 GGAAGAGTCC GTGCTTTAGA AGAGCAGCTT ATAAAGGCCA AAGAACAGAT TGAAAATTAC 300 301 AAGAAACAAA CCAGAAATGG TCTGGGGAAG GATCATGAAA TCCTGAGGAG GAGGATTGAA 360 361 AATGGAGCTA AAGAGCTCTG GTTTTATCTA CAGAGTGAAT TGAAGAAATT AAAGAATTTA 420 421 GAAGGAAGTG AACTCCAAAG ACATGTAGAT GAATTTCTGT CAGATTTGGG ACATCATGAA 480 481 AGGTCTATAA TGACGGATCT ATACTACCTC AGTCAAACAG ATGGAGCAGG TGATTGGCGG 540 541 GAAAAAGAGG CCAAAGATCT GACAGAGCTG GTCCAGAGAA GAATAACGTA TCTTCAGAAT 600 601 CCCAAGGACT GCAGCAAAGC CAAGAAGCTA GTGTGTAATA TCAATAAAGG CTGTGGCTAT 660 661 GGCTGTCAAC TCCATCATGT GGTCTACTGC TTCATGATTG CATATGGCAC CCAGAGAACA 720 721 CTCATCTTGG AATCTCAGAA TTGGCGCTAT GCAACTGGTG GATGGGAGAC TGTGTTTAGA 780 781 CCTGTAAGTG AGACATGCAC AGATAGATCT GGCATCTCCA CTGGACACTG GTCAGGTGAA 840 841 GTGAAAGACA AAAATGTTCA GGTGGTTGAG CTCCCCATCG TAGACAGTCT TCATCCCCGA 900 901 CCTCCGTATT TACCCCTGGC TGTACCAGAA GACCTTGCAG ATCGACTCGT TCGAGTCCAT 960 961 GGTGATCCTG CAGTGTGGTG GGTGTCCCAG TTTGTCAAAT ACTTGATCCG CCCACAACCT 1020 1021 TGGCTGGAAA AGGAAATAGA AGAGGCCACC AAGAAGCTTG GCTTCCAACA TCCAGTTGTT 1080 1081 GGAGTCCATG TCAGACGTAC AGACAAAGTG GGAACAGAAG CAGCCTTCCA TCCCATCGAG 1140 1141 GAGTACATGG TGCATGTTGA AGAACATTTT CAGCTTCTCG CACGCAGGAT GCAGGTGGAC 1200 1201 AAAAAAAGAG TATATTTGGC CACAGATGAC CCCTCTTTAT TAAAGGAGGC AAAAACAAAG 1260 1261 TACCCCAATT ATGAATTTAT TAGTGACAAC TCTATCTCTT GGTCAGCTGG ACTGCACAAC 1320 1321 CGATATACAG AAAATTCACT TCGGGGTGTA ATCCTGGATA TACACTTTCT CTCCCAGGCA 1380 1381 GACTTCCTAG TGTGTACTTT TTCATCCCAG GTCTGTCGAG TTGCTTATGA AATCATGCAA 1440 1441 ACATTGCATC CCGATGCCTC TGCAAACTTC CATTCTTTGG ATGACATCTA CTATTTTGGA 1500 1501 GGCCAGAATG CCCACAACCA GATTGCCATT TATCCTCACC AACCTCGAAC TGCAGATGAA 1560 1561 ATCCCCATGG AGCCTGGAGA TATTATTGGT GTGGCTGGAA ATCATTGGGA TGGCTATTCT 1620 1621 AAAGGTGTCA ACAGAAAACT GGGAAGGACG GGCCTATATC CCTCCTACAA AGTTCAAGAG 1680 1681 AAGATAGAAA CAGTCAAGTA CCCCACATAT CCTGAGGCTG ATAAATAA 1728 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Golgi cisterna membrane | |
Cellular Component | Integral component of membrane | |
Molecular Function | Glycoprotein 6-alpha-L-fucosyltransferase activity | |
Biological Process | Cell migration | |
Biological Process | GDP-L-fucose metabolic process | |
Biological Process | Integrin-mediated signaling pathway | |
Biological Process | N-glycan processing | |
Biological Process | Protein glycosylation in Golgi | |
Biological Process | Protein N-linked glycosylation via asparagine | |
Biological Process | Receptor metabolic process | |
Biological Process | Regulation of cellular response to oxidative stress | |
Biological Process | Regulation of gene expression | |
Biological Process | Respiratory gaseous exchange | |
Biological Process | Transforming growth factor beta receptor signaling pathway |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a044 | Homo sapiens | 0.0 | 1182 | undefined |
| LLPS-Mum-a046 | Mus musculus | 0.0 | 1157 | undefined |