LLPS-Lac-0703
GRB2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Growth factor receptor bound protein 2 |
| Gene Name: | GRB2 |
| Ensembl Gene: | ENSLACG00000000591.1 |
| Ensembl Protein: | ENSLACP00000000662.1 |
| Organism: | Latimeria chalumnae |
| Taxa ID: | 7897 |
| LLPS Type: | Scaffold |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Droplet, Centrosome/Spindle pole body, Stress granule, Receptor cluster | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLACT00000000668.1 | ENSLACP00000000662.1 |
| UniProt | H2ZTE1, H2ZTE1_LATCH | |
| GeneBank | AFYH01091772, AFYH01091770, AFYH01091773, AFYH01091771 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MQCTSFHNGK TKKSSILYLP PFYIFQLLKV LNEECDQNWY KAEISGKDGF IPKNYIEMKP 60 61 HPWFFGKIPR AKAEEMLGKQ RQDGAFLIRE SESAPGDFSL SVKFGNDVQH FKVLRDGAGK 120 121 YFLWVVKFNS LNELVDYHRS TSVSRNQQIF LRDIEQVPQK LHDCFHNNQI SLTGHVKNLE 180 181 TGRVYSLLTI FLQKRHCPFG SFFFGGGELH LMSSNTTKRS HFLKFENKPL QQPTYVQALF 240 241 DFDPQEDGEL GFRRGDFIQV LDNSDPNWWK GACHGQTGMF PRNYVTPVNR NI 292 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCAGTGTA CCTCATTTCA CAATGGTAAA ACAAAAAAAA GCTCAATTTT GTATCTACCA 60 61 CCTTTTTACA TTTTTCAACT GCTTAAAGTA TTAAATGAAG AATGTGATCA AAACTGGTAT 120 121 AAAGCAGAAA TCAGTGGAAA AGATGGCTTC ATTCCTAAAA ATTATATTGA AATGAAACCA 180 181 CATCCTTGGT TTTTTGGTAA AATACCCAGG GCAAAGGCAG AAGAAATGCT TGGTAAACAG 240 241 AGACAAGATG GTGCTTTTCT TATAAGAGAA AGCGAAAGTG CACCTGGGGA TTTCTCACTT 300 301 TCTGTCAAAT TTGGAAATGA TGTACAGCAT TTTAAAGTTC TTCGTGATGG TGCTGGGAAG 360 361 TATTTTCTCT GGGTGGTAAA GTTTAACTCT CTGAATGAAC TGGTGGATTA TCACAGATCT 420 421 ACCTCAGTTT CCCGAAACCA GCAAATATTT CTTCGTGACA TAGAACAGGT TCCACAGAAA 480 481 TTACATGACT GTTTTCACAA TAATCAGATT TCATTAACAG GTCATGTTAA GAATCTTGAA 540 541 ACTGGCAGAG TTTATTCATT GTTGACCATT TTCTTACAAA AGAGGCACTG TCCTTTTGGT 600 601 AGTTTTTTTT TTGGGGGGGG GGAATTGCAC CTCATGTCAT CCAACACCAC TAAGCGTTCT 660 661 CATTTTCTAA AATTTGAAAA TAAACCTCTA CAGCAACCAA CATACGTACA AGCCCTGTTT 720 721 GATTTCGATC CTCAGGAGGA TGGAGAGTTG GGATTCCGTC GTGGCGATTT TATCCAGGTT 780 781 CTTGATAACT CAGATCCGAA TTGGTGGAAA GGAGCTTGCC ATGGGCAGAC AGGCATGTTC 840 841 CCTCGAAACT ACGTGACCCC TGTAAATCGA AACATTTAA 879 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Xet-3767 | Xenopus tropicalis | 96.99 | 7e-89 | 271 |
| LLPS-Anp-0508 | Anas platyrhynchos | 96.95 | 4e-87 | 266 |
| LLPS-Fia-3669 | Ficedula albicollis | 96.27 | 8e-89 | 271 |
| LLPS-Meg-1203 | Meleagris gallopavo | 96.27 | 8e-89 | 271 |
| LLPS-Mod-1313 | Monodelphis domestica | 96.27 | 8e-89 | 271 |
| LLPS-Anc-3657 | Anolis carolinensis | 96.27 | 7e-89 | 271 |
| LLPS-Tag-1741 | Taeniopygia guttata | 96.27 | 8e-89 | 271 |
| LLPS-Gaga-3593 | Gallus gallus | 96.27 | 8e-89 | 271 |
| LLPS-Ova-0545 | Ovis aries | 96.24 | 4e-88 | 269 |
| LLPS-Fud-4366 | Fukomys damarensis | 95.52 | 5e-88 | 269 |
| LLPS-Caj-2802 | Callithrix jacchus | 95.52 | 5e-88 | 269 |
| LLPS-Gog-0055 | Gorilla gorilla | 95.52 | 5e-88 | 269 |
| LLPS-Aon-1471 | Aotus nancymaae | 95.52 | 5e-88 | 269 |
| LLPS-Cea-0827 | Cercocebus atys | 95.52 | 5e-88 | 269 |
| LLPS-Sus-0356 | Sus scrofa | 95.52 | 5e-88 | 269 |
| LLPS-Mea-0768 | Mesocricetus auratus | 95.52 | 4e-88 | 269 |
| LLPS-Maf-3331 | Macaca fascicularis | 95.52 | 5e-88 | 269 |
| LLPS-Chs-3262 | Chlorocebus sabaeus | 95.52 | 5e-88 | 269 |
| LLPS-Mal-0689 | Mandrillus leucophaeus | 95.52 | 4e-88 | 269 |
| LLPS-Paa-2270 | Papio anubis | 95.52 | 5e-88 | 269 |
| LLPS-Mup-0708 | Mustela putorius furo | 95.52 | 5e-88 | 269 |
| LLPS-Myl-4356 | Myotis lucifugus | 95.52 | 5e-88 | 269 |
| LLPS-Ran-2028 | Rattus norvegicus | 95.52 | 5e-88 | 269 |
| LLPS-Dio-4311 | Dipodomys ordii | 95.52 | 5e-88 | 269 |
| LLPS-Bot-3287 | Bos taurus | 95.52 | 5e-88 | 269 |
| LLPS-Orc-3409 | Oryctolagus cuniculus | 95.52 | 5e-88 | 269 |
| LLPS-Rhb-1950 | Rhinopithecus bieti | 95.52 | 5e-88 | 269 |
| LLPS-Otg-2488 | Otolemur garnettii | 95.52 | 5e-88 | 269 |
| LLPS-Pes-2879 | Pelodiscus sinensis | 95.52 | 4e-88 | 269 |
| LLPS-Man-2683 | Macaca nemestrina | 95.52 | 5e-88 | 269 |
| LLPS-Pat-1955 | Pan troglodytes | 95.52 | 5e-88 | 269 |
| LLPS-Pap-2127 | Pan paniscus | 95.52 | 5e-88 | 269 |
| LLPS-Urm-3048 | Ursus maritimus | 95.52 | 5e-88 | 269 |
| LLPS-Hos-1126 | Homo sapiens | 95.52 | 5e-88 | 269 |
| LLPS-Fec-4440 | Felis catus | 95.52 | 5e-88 | 269 |
| LLPS-Ict-2782 | Ictidomys tridecemlineatus | 95.52 | 5e-88 | 269 |
| LLPS-Nol-1797 | Nomascus leucogenys | 95.52 | 5e-88 | 269 |
| LLPS-Cas-3293 | Carlito syrichta | 95.52 | 5e-88 | 269 |
| LLPS-Mam-2993 | Macaca mulatta | 95.52 | 5e-88 | 269 |
| LLPS-Poa-0227 | Pongo abelii | 95.52 | 5e-88 | 269 |
| LLPS-Caf-2348 | Canis familiaris | 95.52 | 5e-88 | 269 |
| LLPS-Eqc-3391 | Equus caballus | 95.52 | 5e-88 | 269 |
| LLPS-Cap-3753 | Cavia porcellus | 95.52 | 5e-88 | 269 |
| LLPS-Leo-2654 | Lepisosteus oculatus | 95.49 | 6e-87 | 266 |
| LLPS-Aim-3644 | Ailuropoda melanoleuca | 95.45 | 2e-86 | 264 |
| LLPS-Mum-4436 | Mus musculus | 94.78 | 1e-87 | 268 |
| LLPS-Gaa-3259 | Gasterosteus aculeatus | 94.78 | 5e-87 | 266 |
| LLPS-Scf-1099 | Scleropages formosus | 94.03 | 3e-86 | 264 |
| LLPS-Loa-0716 | Loxodonta africana | 94.03 | 2e-86 | 265 |
| LLPS-Orl-1653 | Oryzias latipes | 93.33 | 2e-86 | 265 |
| LLPS-Icp-1162 | Ictalurus punctatus | 92.54 | 7e-86 | 263 |
| LLPS-Xim-0975 | Xiphophorus maculatus | 92.54 | 3e-85 | 262 |
| LLPS-Pof-1785 | Poecilia formosa | 92.54 | 3e-85 | 262 |
| LLPS-Asm-3107 | Astyanax mexicanus | 91.79 | 9e-85 | 260 |
| LLPS-Dar-3113 | Danio rerio | 91.79 | 3e-85 | 262 |
| LLPS-Scm-0763 | Scophthalmus maximus | 91.43 | 4e-88 | 269 |
| LLPS-Orn-4004 | Oreochromis niloticus | 90.98 | 2e-82 | 254 |
| LLPS-Ten-2338 | Tetraodon nigroviridis | 90.72 | 1e-57 | 188 |
| LLPS-Tar-3979 | Takifugu rubripes | 87.05 | 1e-81 | 253 |
| LLPS-Cis-1256 | Ciona savignyi | 71.43 | 2e-55 | 187 |
| LLPS-Cii-2332 | Ciona intestinalis | 60.32 | 8e-43 | 150 |
| LLPS-Ora-0049 | Ornithorhynchus anatinus | 57.14 | 5e-15 | 77.8 |
| LLPS-Scc-0314 | Schizosaccharomyces cryophilus | 55.77 | 2e-13 | 73.9 |
| LLPS-Sah-1051 | Sarcophilus harrisii | 44.44 | 5e-06 | 51.6 |
| LLPS-Ere-0346 | Erinaceus europaeus | 36.43 | 1e-13 | 73.9 |