• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Kop-1145
PAS_chr2-1_0246

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: V-type proton ATPase subunit C
Gene Name: PAS_chr2-1_0246
Ensembl Gene: PAS_chr2-1_0246
Ensembl Protein: CAY68858
Organism: Komagataella pastoris
Taxa ID: 644223
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION


Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblCAY68858CAY68858
UniProtC4R034, C4R034_KOMPG
GeneBankFN392320CAY68858.1
RefSeqXM_002491093.1XP_002491138.1

▼ SEQUENCE


Protein Sequence (FASTA)
1     MAEPLGSYLL  ISLPKTQNLL  HDETQDWLET  NVNGGKVSVT  NVDVPEFKIG  TLDTLMQQTE  60
61    EISKLDNQLN  QAVNKVLEII  QTVFDKNPAF  VEQAKQVEGR  SVIDYLENFK  WNTSKYRTDR  120
121   SIRQLIDTIS  LDGLNLDNDV  KATFQNYNSA  KSNLAAAERK  RTGDLTVKSL  HDIVDETDFV  180
181   LDSDHLQTIL  LVIPKNLVQS  FLNTYETVVP  FVVPRSAKRI  TADSEFVLYS  VILFKKYVPE  240
241   FLAAARENKW  ITREFNYDEE  SIKLLRNEYN  DASTQEHSLR  NDLIRLVKAA  YADIVSSWLH  300
301   IKILRTFIES  VLRYGIPPDF  SYFLLKLPHK  AIEKGKSQLV  EKFGYLGGAA  VGVDRRGKIV  360
361   KDSLHEYASL  VDTDYQPFVL  YELEIN  386
Nucleotide CDS Sequence (FASTA)
1     ATGGCAGAAC  CATTGGGCAG  TTATTTGCTG  ATCTCTCTGC  CGAAAACGCA  AAACCTACTC  60
61    CACGATGAGA  CGCAGGATTG  GCTGGAGACT  AACGTGAATG  GAGGAAAAGT  TTCAGTCACC  120
121   AACGTTGACG  TTCCTGAGTT  CAAGATTGGC  ACCCTAGACA  CCTTGATGCA  ACAGACGGAG  180
181   GAAATCTCCA  AGTTGGACAA  TCAGTTGAAC  CAGGCTGTTA  ACAAGGTGTT  AGAAATCATA  240
241   CAGACTGTCT  TTGACAAAAA  CCCAGCGTTT  GTGGAACAGG  CTAAACAAGT  AGAGGGTCGT  300
301   TCTGTCATTG  ACTATCTTGA  AAATTTCAAA  TGGAACACAT  CAAAGTATAG  AACCGACCGT  360
361   TCAATTCGCC  AGTTAATTGA  CACCATATCT  TTGGATGGAT  TGAATCTAGA  CAATGACGTG  420
421   AAAGCTACAT  TTCAAAACTA  TAACTCTGCA  AAGTCCAACT  TGGCCGCTGC  AGAGCGCAAA  480
481   CGAACTGGAG  ATTTGACGGT  AAAGTCGTTG  CATGATATTG  TTGATGAGAC  TGATTTTGTT  540
541   CTAGACTCTG  ATCATTTGCA  GACAATTCTG  TTAGTCATTC  CAAAGAATTT  GGTGCAGTCT  600
601   TTCCTCAATA  CCTACGAGAC  TGTGGTACCA  TTTGTGGTTC  CCAGAAGTGC  TAAAAGAATT  660
661   ACTGCTGATT  CAGAGTTTGT  GCTGTATAGT  GTCATCTTAT  TCAAGAAGTA  CGTGCCCGAA  720
721   TTCTTGGCTG  CAGCTAGAGA  GAACAAGTGG  ATTACTCGTG  AGTTTAACTA  TGATGAGGAG  780
781   TCAATTAAAC  TGCTGAGAAA  TGAGTACAAC  GATGCCAGCA  CACAGGAGCA  TTCATTGAGG  840
841   AACGATCTGA  TAAGATTGGT  TAAGGCTGCT  TATGCGGATA  TAGTCAGTTC  GTGGTTACAC  900
901   ATCAAAATAT  TGAGAACTTT  CATCGAGTCA  GTTTTGCGTT  ACGGAATCCC  TCCAGATTTT  960
961   TCATATTTCC  TGTTAAAATT  ACCCCACAAA  GCCATTGAGA  AAGGTAAATC  CCAGTTGGTA  1020
1021  GAGAAGTTTG  GTTATTTGGG  AGGGGCTGCC  GTCGGGGTTG  ACCGTCGTGG  TAAAATTGTC  1080
1081  AAAGATTCTC  TACATGAATA  TGCCAGTCTG  GTGGATACCG  ACTATCAACC  ATTTGTGCTA  1140
1141  TATGAGCTGG  AGATTAACTA  G  1161

▼ KEYWORD


ID
Family
Coiled coil
Complete proteome
Hydrogen ion transport
Ion transport
Reference proteome
Transport

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Proton-transporting V-type ATPase, V1 domain
Molecular Function
Proton transmembrane transporter activity
Biological Process
ATP hydrolysis coupled proton transport

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sac-1242Saccharomyces cerevisiae49.68e-127 378
LLPS-Yal-1345Yarrowia lipolytica43.081e-100 310
LLPS-Asc-1126Aspergillus clavatus40.261e-92 290
LLPS-Asf-1174Aspergillus flavus39.84e-92 289
LLPS-Aso-1029Aspergillus oryzae39.84e-92 289
LLPS-Asg-1126Ashbya gossypii39.796e-85 270
LLPS-Scj-0689Schizosaccharomyces japonicus39.417e-77 249
LLPS-Lem-0346Leptosphaeria maculans39.283e-88 279
LLPS-Asn-0323Aspergillus nidulans39.273e-91 286
LLPS-Coo-0392Colletotrichum orbiculare39.269e-83 265
LLPS-Asni-1117Aspergillus niger39.017e-92 288
LLPS-Tum-0366Tuber melanosporum38.965e-87 275
LLPS-Nef-1279Neosartorya fischeri38.441e-92 290
LLPS-Asfu-0342Aspergillus fumigatus38.441e-91 287
LLPS-Cog-0253Colletotrichum gloeosporioides38.382e-84 269
LLPS-Phn-0760Phaeosphaeria nodorum37.822e-81 261
LLPS-Trr-0065Trichoderma reesei37.61e-85 272
LLPS-Scs-0660Sclerotinia sclerotiorum37.51e-73 240
LLPS-Mao-1588Magnaporthe oryzae37.43e-86 273
LLPS-Blg-0439Blumeria graminis37.341e-87 277
LLPS-Cogr-0796Colletotrichum graminicola37.256e-83 265
LLPS-Pytr-1007Pyrenophora triticirepentis37.215e-87 276
LLPS-Trv-0558Trichoderma virens37.112e-84 269
LLPS-Gaa-1847Gasterosteus aculeatus37.061e-62 212
LLPS-Map-0889Magnaporthe poae36.952e-85 271
LLPS-Gag-0887Gaeumannomyces graminis36.951e-85 272
LLPS-Pyt-1545Pyrenophora teres36.951e-85 272
LLPS-Fuv-0635Fusarium verticillioides36.861e-85 272
LLPS-Fuo-1043Fusarium oxysporum36.864e-86 273
LLPS-Dos-0885Dothistroma septosporum36.363e-82 263
LLPS-Ast-1320Aspergillus terreus36.312e-27 113
LLPS-Beb-1175Beauveria bassiana36.154e-82 263
LLPS-Zyt-1514Zymoseptoria tritici36.134e-87 276
LLPS-Ved-0472Verticillium dahliae35.98e-82 262
LLPS-Tar-3873Takifugu rubripes35.281e-64 217
LLPS-Xim-3446Xiphophorus maculatus35.284e-65 219
LLPS-Pof-3104Poecilia formosa35.288e-66 220
LLPS-Usm-0959Ustilago maydis35.16e-69 229
LLPS-Nec-0193Neurospora crassa34.871e-78 254
LLPS-Drm-1488Drosophila melanogaster34.861e-51 189
LLPS-Ora-2618Ornithorhynchus anatinus34.787e-63 213
LLPS-Scf-4002Scleropages formosus34.468e-69 229
LLPS-Fus-1454Fusarium solani34.283e-70 232
LLPS-Spr-1406Sporisorium reilianum34.261e-65 220
LLPS-Abg-1756Absidia glauca34.113e-73 240
LLPS-Leo-1320Lepisosteus oculatus33.945e-67 224
LLPS-Dar-1146Danio rerio33.855e-65 218
LLPS-Ten-3420Tetraodon nigroviridis33.853e-64 216
LLPS-Mua-0726Musa acuminata33.822e-31 125
LLPS-Xet-1872Xenopus tropicalis33.822e-62 211
LLPS-Orn-2474Oreochromis niloticus33.773e-67 224
LLPS-Cae-1882Caenorhabditis elegans33.681e-64 217
LLPS-Loa-0654Loxodonta africana33.591e-65 220
LLPS-Icp-0161Ictalurus punctatus33.514e-67 224
LLPS-Asm-1282Astyanax mexicanus33.512e-67 224
LLPS-Ran-3977Rattus norvegicus33.422e-65 219
LLPS-Scp-0778Schizosaccharomyces pombe33.338e-74 241
LLPS-Gog-2668Gorilla gorilla33.164e-65 218
LLPS-Chs-3879Chlorocebus sabaeus33.164e-65 218
LLPS-Maf-2095Macaca fascicularis33.164e-65 218
LLPS-Mum-3218Mus musculus33.162e-64 217
LLPS-Aon-3824Aotus nancymaae33.166e-65 218
LLPS-Cea-4702Cercocebus atys33.164e-65 218
LLPS-Orl-0987Oryzias latipes33.164e-65 218
LLPS-Mup-1310Mustela putorius furo33.164e-65 218
LLPS-Ova-2472Ovis aries33.163e-64 218
LLPS-Paa-3482Papio anubis33.164e-65 218
LLPS-Mal-3177Mandrillus leucophaeus33.164e-65 218
LLPS-Tut-1293Tursiops truncatus33.169e-62 209
LLPS-Bot-1577Bos taurus33.164e-65 218
LLPS-Dio-0645Dipodomys ordii33.164e-65 218
LLPS-Otg-1354Otolemur garnettii33.168e-65 218
LLPS-Rhb-0058Rhinopithecus bieti33.164e-65 218
LLPS-Orc-2428Oryctolagus cuniculus33.165e-65 218
LLPS-Fec-0332Felis catus33.169e-65 218
LLPS-Pat-3847Pan troglodytes33.164e-65 218
LLPS-Pap-2295Pan paniscus33.164e-65 218
LLPS-Urm-1846Ursus maritimus33.163e-65 219
LLPS-Hos-4579Homo sapiens33.164e-65 218
LLPS-Man-4571Macaca nemestrina33.164e-65 218
LLPS-Cas-1110Carlito syrichta33.165e-65 218
LLPS-Ict-4185Ictidomys tridecemlineatus33.166e-65 218
LLPS-Nol-1484Nomascus leucogenys33.164e-65 218
LLPS-Eqc-4167Equus caballus33.161e-64 218
LLPS-Caf-3992Canis familiaris33.164e-65 219
LLPS-Mam-0584Macaca mulatta33.164e-65 218
LLPS-Gor-1139Gossypium raimondii33.116e-46 167
LLPS-Zem-0989Zea mays33.07e-50 178
LLPS-Prp-1489Prunus persica33.08e-48 172
LLPS-Caj-1361Callithrix jacchus32.99e-64 215
LLPS-Aim-3325Ailuropoda melanoleuca32.91e-64 217
LLPS-Anc-3134Anolis carolinensis32.92e-65 219
LLPS-Sah-3456Sarcophilus harrisii32.822e-63 214
LLPS-Sus-4663Sus scrofa32.821e-64 218
LLPS-Pug-1272Puccinia graminis32.77e-57 199
LLPS-Cus-1779Cucumis sativus32.664e-46 168
LLPS-Mod-3864Monodelphis domestica32.661e-57 199
LLPS-Pes-3521Pelodiscus sinensis32.649e-64 215
LLPS-Meg-3324Meleagris gallopavo32.642e-63 214
LLPS-Gaga-3678Gallus gallus32.642e-63 214
LLPS-Fud-3877Fukomys damarensis32.561e-64 217
LLPS-Orp-2201Oryza punctata32.471e-49 186
LLPS-Scm-1548Scophthalmus maximus32.461e-63 214
LLPS-Amt-2023Amborella trichopoda32.451e-52 185
LLPS-Fia-1998Ficedula albicollis32.381e-62 212
LLPS-Cap-2864Cavia porcellus32.34e-63 213
LLPS-Tra-2647Triticum aestivum32.253e-46 169
LLPS-Scc-1522Schizosaccharomyces cryophilus32.27e-72 236
LLPS-Lac-3779Latimeria chalumnae32.21e-59 204
LLPS-Orm-0360Oryza meridionalis32.182e-51 186
LLPS-Ori-2473Oryza indica32.165e-53 186
LLPS-Orgl-1765Oryza glumaepatula32.169e-51 186
LLPS-Ors-1247Oryza sativa32.165e-53 186
LLPS-Org-0315Oryza glaberrima32.165e-53 186
LLPS-Orr-2220Oryza rufipogon32.165e-53 186
LLPS-Hov-2079Hordeum vulgare32.133e-45 166
LLPS-Poa-3076Pongo abelii32.119e-62 209
LLPS-Put-1071Puccinia triticina32.077e-56 195
LLPS-Mel-0158Melampsora laricipopulina32.033e-56 196
LLPS-Glm-2205Glycine max31.992e-44 163
LLPS-Viv-1568Vitis vinifera31.992e-46 169
LLPS-Brd-1655Brachypodium distachyon31.929e-48 172
LLPS-Orbr-2255Oryza brachyantha31.871e-52 185
LLPS-Orni-1735Oryza nivara31.799e-51 181
LLPS-Php-0894Physcomitrella patens31.788e-52 183
LLPS-Sob-1366Sorghum bicolor31.495e-51 181
LLPS-Met-0343Medicago truncatula31.457e-46 167
LLPS-Orb-0669Oryza barthii31.352e-49 177
LLPS-Phv-1275Phaseolus vulgaris31.317e-44 162
LLPS-Tru-1028Triticum urartu31.15e-43 159
LLPS-Anp-1143Anas platyrhynchos31.041e-57 199
LLPS-Art-0728Arabidopsis thaliana30.841e-48 174
LLPS-Sei-2269Setaria italica30.795e-51 181
LLPS-Lep-1943Leersia perrieri30.791e-49 177
LLPS-Chc-0321Chondrus crispus30.72e-50 179
LLPS-Sem-2358Selaginella moellendorffii30.615e-49 176
LLPS-Chr-1121Chlamydomonas reinhardtii30.596e-49 175
LLPS-Dac-0854Daucus carota30.546e-45 165
LLPS-Thc-2002Theobroma cacao30.541e-47 172
LLPS-Hea-0927Helianthus annuus30.521e-46 169
LLPS-Vir-1545Vigna radiata30.381e-47 172
LLPS-Cym-0112Cyanidioschyzon merolae30.316e-38 145
LLPS-Cis-1356Ciona savignyi30.312e-49 177
LLPS-Myl-3962Myotis lucifugus30.32e-58 202
LLPS-Brn-0178Brassica napus30.244e-48 173
LLPS-Brr-0605Brassica rapa30.244e-48 173
LLPS-Pot-0617Populus trichocarpa29.975e-42 157
LLPS-Sol-2499Solanum lycopersicum29.942e-48 174
LLPS-Arl-1253Arabidopsis lyrata29.941e-47 172
LLPS-Mae-1364Manihot esculenta29.947e-46 167
LLPS-Bro-2767Brassica oleracea29.944e-48 173
LLPS-Crn-1444Cryptococcus neoformans29.866e-54 189
LLPS-Tag-2730Taeniopygia guttata29.72e-51 183
LLPS-Coc-1435Corchorus capsularis29.644e-46 168
LLPS-Via-2419Vigna angularis29.572e-46 169
LLPS-Mea-3624Mesocricetus auratus29.045e-47 171
LLPS-Miv-1087Microbotryum violaceum28.418e-54 190
LLPS-Gas-0700Galdieria sulphuraria28.294e-43 159
LLPS-Nia-1192Nicotiana attenuata28.281e-33 132
LLPS-Osl-1083Ostreococcus lucimarinus27.961e-43 161